DegronMD

Uniprot ID: Q8NI35

Source protein: InaD-like protein

Source gene: PATJ

Class: DEG_APCC_KENBOX_2

Location: 179:183

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9898

ASA_SCORE: 71.16

COIL: 0.8734

CONS_SCORE: 0.6464

DSS_SCORE: 0.4096

HELIX: 0.0058

FCONS_SCORE: 1.0472

RIG_SCORE: 0.7905

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P192S	SIDM01782	Oral Cavity Carcinoma	GDSC	LKEND	DEG_APCC_KENBOX_2	0.0833

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O15344	E3 ubiquitin-protein ligase Midline-1	DEG_APCC_KENBOX_2	320:324	LKEND	APC,CDC20,FZR1	0.7656	More...
P29374	AT-rich interactive domain-containing protein 4A	DEG_APCC_KENBOX_2	744:748	LKEND	APC,CDC20,FZR1	0.5299	More...
P46013	Proliferation marker protein Ki-67	DEG_APCC_KENBOX_2	938:942	LKEND	APC,CDC20,FZR1	0.9316	More...
Q12923	Tyrosine-protein phosphatase non-receptor type 13	DEG_APCC_KENBOX_2	1071:1075	LKEND	APC,CDC20,FZR1	0.9955	More...
Q14739	Delta	DEG_APCC_KENBOX_2	49:53	LKEND	APC,CDC20,FZR1	0.9324	More...
Q8NI35	InaD-like protein	DEG_APCC_KENBOX_2	179:183	LKEND	APC,CDC20,FZR1	0.9898	More...
Q92743	Serine protease HTRA1	DEG_APCC_KENBOX_2	428:432	LKEND	APC,CDC20,FZR1	0.9566	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons