SZGR2

Summary ?

GeneID	7704
Symbol	ZBTB16
Synonyms	PLZF\|ZNF145
Description	zinc finger and BTB domain containing 16
Reference	MIM:176797\|HGNC:HGNC:12930\|Ensembl:ENSG00000109906\|HPRD:11762\|Vega:OTTHUMG00000168243
Gene type	protein-coding
Map location	11q23.1
Pascal p-value	0.733
Sherlock p-value	0.64
Fetal beta	-2.017
DMG	1 (# studies)

Gene in Data Sources

Gene set name	Method of gene set	Description	Info
CV:GWASdb	Genome-wide Association Studies	GWASdb records for schizophrenia
CV:PGCnp	Genome-wide Association Study	GWAS
DMG:Jaffe_2016	Genome-wide DNA methylation analysis	This dataset includes 2,104 probes/CpGs associated with SZ patients (n=108) compared to 136 controls at Bonferroni-adjusted P < 0.05.	1
GSMA_I	Genome scan meta-analysis	Psr: 0.006
Expression	Meta-analysis of gene expression	P value: 2.137
GO_Annotation	Mapping neuro-related keywords to Gene Ontology annotations	Hits with neuro-related keywords: 1

Section I. Genetics and epigenetics annotation

Differentially methylated gene

Probe	Chromosome	Position	Nearest gene	P (dis)	Beta (dis)	FDR (dis)	Study
cg07673133	11	113930011	ZBTB16	1.22E-8	-0.015	4.99E-6	DMG:Jaffe_2016

Section II. Transcriptome annotation

General gene expression (GTEx)

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
DDX5	0.96	0.94
ZNF285B	0.95	0.91
UIMC1	0.95	0.88
C1orf26	0.95	0.93
CEP57	0.95	0.93
HSF2	0.94	0.93
ZCCHC7	0.94	0.94
ZNF586	0.94	0.88
WTAP	0.94	0.94
TEX10	0.94	0.91

Top 10 negatively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
HLA-F	-0.71	-0.80
AIFM3	-0.70	-0.79
AF347015.31	-0.69	-0.87
AF347015.27	-0.69	-0.86
MT-CO2	-0.68	-0.87
FBXO2	-0.68	-0.70
PTH1R	-0.68	-0.74
C5orf53	-0.67	-0.72
IFI27	-0.67	-0.86
MT-CYB	-0.67	-0.86

Section III. Gene Ontology annotation

Molecular function	GO term	Evidence	Neuro keywords	PubMed ID
GO:0003677	DNA binding	NAS		9294197
GO:0008270	zinc ion binding	IEA		-
GO:0016566	specific transcriptional repressor activity	IDA		12802276
GO:0042803	protein homodimerization activity	IDA		8622986
GO:0046872	metal ion binding	IEA		-
Biological process	GO term	Evidence	Neuro keywords	PubMed ID
GO:0007417	central nervous system development	ISS	Brain (GO term level: 6)	8541544
GO:0001823	mesonephros development	ISS		8541544
GO:0006350	transcription	IEA		-
GO:0006511	ubiquitin-dependent protein catabolic process	IEA		-
GO:0006915	apoptosis	NAS		9294197
GO:0045638	negative regulation of myeloid cell differentiation	ISS		8541544
GO:0045892	negative regulation of transcription, DNA-dependent	IDA		12802276
Cellular component	GO term	Evidence	Neuro keywords	PubMed ID
GO:0005622	intracellular	IEA		-
GO:0005634	nucleus	IDA		9294197
GO:0005730	nucleolus	IDA		18029348
GO:0016607	nuclear speck	IDA		8541544
GO:0016605	PML body	IDA		9294197
GO:0017053	transcriptional repressor complex	IDA		12802276

Section IV. Protein-protein interaction annotation

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
AGTR1	AG2S \| AGTR1A \| AGTR1B \| AT1 \| AT1B \| AT1R \| AT2R1 \| AT2R1A \| AT2R1B \| HAT1R	angiotensin II receptor, type 1	Reconstituted Complex Two-hybrid	BioGRID	14657020
AGTR2	AT2 \| ATGR2 \| MRX88	angiotensin II receptor, type 2	-	HPRD	14657020
ANAPC5	APC5	anaphase promoting complex subunit 5	Two-hybrid	BioGRID	16169070
BCL6	BCL5 \| BCL6A \| LAZ3 \| ZBTB27 \| ZNF51	B-cell CLL/lymphoma 6	-	HPRD,BioGRID	11175338
BMI1	MGC12685 \| PCGF4 \| RNF51	BMI1 polycomb ring finger oncogene	-	HPRD,BioGRID	12408802
CCDC109B	FLJ20647	coiled-coil domain containing 109B	Two-hybrid	BioGRID	16169070
CCDC130	MGC10471	coiled-coil domain containing 130	Two-hybrid	BioGRID	16169070
CCDC85B	DIPA	coiled-coil domain containing 85B	Two-hybrid	BioGRID	16189514
CD81	S5.7 \| TAPA1 \| TSPAN28	CD81 molecule	Two-hybrid	BioGRID	16169070
CDC2	CDC28A \| CDK1 \| DKFZp686L20222 \| MGC111195	cell division cycle 2, G1 to S and G2 to M	-	HPRD,BioGRID	10497277
CEP70	BITE \| FLJ13036	centrosomal protein 70kDa	Two-hybrid	BioGRID	16189514
CEP72	FLJ10565 \| KIAA1519 \| MGC5307	centrosomal protein 72kDa	Two-hybrid	BioGRID	16189514
CIDEA	CIDE-A	cell death-inducing DFFA-like effector a	Two-hybrid	BioGRID	16169070
COQ6	CGI-10	coenzyme Q6 homolog, monooxygenase (S. cerevisiae)	Two-hybrid	BioGRID	16169070
DLST	DLTS	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)	Two-hybrid	BioGRID	16169070
DPM1	CDGIE \| MPDS	dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit	Two-hybrid	BioGRID	16169070
EIF2S2	DKFZp686L18198 \| EIF2 \| EIF2B \| EIF2beta \| MGC8508	eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa	Two-hybrid	BioGRID	16169070
ENOX1	CNOX \| FLJ10094 \| PIG38 \| bA64J21.1 \| cCNOX	ecto-NOX disulfide-thiol exchanger 1	Two-hybrid	BioGRID	16189514
EPN1	-	epsin 1	-	HPRD	10791968
ESR1	DKFZp686N23123 \| ER \| ESR \| ESRA \| Era \| NR3A1	estrogen receptor 1	-	HPRD,BioGRID	14521715
FAM101B	MGC45871	family with sequence similarity 101, member B	Two-hybrid	BioGRID	16169070
FCHO1	KIAA0290	FCH domain only 1	Two-hybrid	BioGRID	16169070
FHL2	AAG11 \| DRAL \| SLIM3	four and a half LIM domains 2	-	HPRD,BioGRID	12145280
GATA1	ERYF1 \| GF-1 \| GF1 \| NFE1	GATA binding protein 1 (globin transcription factor 1)	-	HPRD,BioGRID	12242665
GATA2	MGC2306 \| NFE1B	GATA binding protein 2	-	HPRD,BioGRID	11964310
GCSH	GCE \| NKH	glycine cleavage system protein H (aminomethyl carrier)	Two-hybrid	BioGRID	16169070
GSTM4	GSTM4-4 \| GTM4 \| MGC131945 \| MGC9247	glutathione S-transferase mu 4	Two-hybrid	BioGRID	16169070
HBEGF	DTR \| DTS \| DTSF \| HEGFL	heparin-binding EGF-like growth factor	-	HPRD,BioGRID	14597771 \|15219838
HBXIP	MGC71071 \| XIP	hepatitis B virus x interacting protein	Two-hybrid	BioGRID	16169070
HDAC1	DKFZp686H12203 \| GON-10 \| HD1 \| RPD3 \| RPD3L1	histone deacetylase 1	-	HPRD	9627120 \|15467736
HDAC1	DKFZp686H12203 \| GON-10 \| HD1 \| RPD3 \| RPD3L1	histone deacetylase 1	Affinity Capture-Western Reconstituted Complex	BioGRID	9627120 \|9765306 \|15467736
HDAC1	DKFZp686H12203 \| GON-10 \| HD1 \| RPD3 \| RPD3L1	histone deacetylase 1	HDAC1 interacts with PLZF. This interaction was modelled on a demonstrated interaction between HDAC1 and PLZF from unspecified species.	BIND	9486654
HDAC2	RPD3 \| YAF1	histone deacetylase 2	Reconstituted Complex	BioGRID	15467736
HDAC3	HD3 \| RPD3 \| RPD3-2	histone deacetylase 3	Reconstituted Complex	BioGRID	15467736
HDAC4	HA6116 \| HD4 \| HDAC-A \| HDACA \| KIAA0288	histone deacetylase 4	-	HPRD,BioGRID	11929873 \|15467736
HDAC5	FLJ90614 \| HD5 \| NY-CO-9	histone deacetylase 5	-	HPRD,BioGRID	11929873 \|15467736
HDAC6	FLJ16239 \| HD6 \| JM21	histone deacetylase 6	-	HPRD,BioGRID	15467736
HDAC7	DKFZp586J0917 \| FLJ99588 \| HD7A \| HDAC7A	histone deacetylase 7	Reconstituted Complex	BioGRID	11929873
HDAC9	DKFZp779K1053 \| HD7 \| HDAC \| HDAC7 \| HDAC7B \| HDAC9B \| HDAC9FL \| HDRP \| KIAA0744 \| MITR	histone deacetylase 9	-	HPRD	12590135
HEATR2	FLJ20397 \| FLJ25564 \| FLJ31671 \| FLJ39381	HEAT repeat containing 2	Two-hybrid	BioGRID	16169070
KRTAP4-12	KAP4.12 \| KRTAP4.12	keratin associated protein 4-12	Two-hybrid	BioGRID	16189514
LDOC1	BCUR1 \| Mar7 \| Mart7	leucine zipper, down-regulated in cancer 1	Two-hybrid	BioGRID	16189514
LMTK3	KIAA1883 \| LMR3 \| TYKLM3	lemur tyrosine kinase 3	Two-hybrid	BioGRID	16169070
LSM2	C6orf28 \| G7b \| YBL026W \| snRNP	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	Two-hybrid	BioGRID	16169070
LYAR	FLJ20425 \| ZLYAR	Ly1 antibody reactive homolog (mouse)	Two-hybrid	BioGRID	16169070
MAGEA11	MAGE-11 \| MAGE11 \| MAGEA-11 \| MGC10511	melanoma antigen family A, 11	Two-hybrid	BioGRID	16189514
MAP3K3	MAPKKK3 \| MEKK3	mitogen-activated protein kinase kinase kinase 3	Two-hybrid	BioGRID	16169070
NCOR1	KIAA1047 \| MGC104216 \| N-CoR \| TRAC1 \| hCIT529I10 \| hN-CoR	nuclear receptor co-repressor 1	-	HPRD,BioGRID	9531570
NCOR2	CTG26 \| SMRT \| SMRTE \| SMRTE-tau \| TNRC14 \| TRAC-1 \| TRAC1	nuclear receptor co-repressor 2	-	HPRD	9256429 \|14982881
NCOR2	CTG26 \| SMRT \| SMRTE \| SMRTE-tau \| TNRC14 \| TRAC-1 \| TRAC1	nuclear receptor co-repressor 2	Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	9256429 \|9765306 \|14982881
NCOR2	CTG26 \| SMRT \| SMRTE \| SMRTE-tau \| TNRC14 \| TRAC-1 \| TRAC1	nuclear receptor co-repressor 2	SMRT interacts with PLZF. This interaction was modelled on a demonstrated interaction between SMRT and PLZF from unspecified species.	BIND	9486654
NR3C1	GCCR \| GCR \| GR \| GRL	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	-	HPRD,BioGRID	14521715
PAFAH1B3	-	platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDa	Two-hybrid	BioGRID	16169070
PGAM5	BXLBv68 \| MGC5352	phosphoglycerate mutase family member 5	Two-hybrid	BioGRID	16169070
PLSCR1	MMTRA1B	phospholipid scramblase 1	Two-hybrid	BioGRID	16189514
PMAIP1	APR \| NOXA	phorbol-12-myristate-13-acetate-induced protein 1	Two-hybrid	BioGRID	16169070
PML	MYL \| PP8675 \| RNF71 \| TRIM19	promyelocytic leukemia	-	HPRD,BioGRID	9294197 \|11175338
PSMD11	MGC3844 \| Rpn6 \| S9 \| p44.5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	Two-hybrid	BioGRID	16169070
PSMD2	MGC14274 \| P97 \| Rpn1 \| S2 \| TRAP2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	Two-hybrid	BioGRID	16169070
QTRT1	FP3235 \| TGT	queuine tRNA-ribosyltransferase 1	Two-hybrid	BioGRID	16169070
RAB27A	GS2 \| HsT18676 \| MGC117246 \| RAB27 \| RAM	RAB27A, member RAS oncogene family	Two-hybrid	BioGRID	16169070
RARA	NR1B1 \| RAR	retinoic acid receptor, alpha	-	HPRD,BioGRID	14521715
RB1	OSRC \| RB \| p105-Rb \| pRb \| pp110	retinoblastoma 1	pRB interacts with PLZF.	BIND	15949438
RUNX1T1	AML1T1 \| CBFA2T1 \| CDR \| ETO \| MGC2796 \| MTG8 \| MTG8b \| ZMYND2	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	-	HPRD,BioGRID	10688654 \|11090081
RXRA	FLJ00280 \| FLJ00318 \| FLJ16020 \| FLJ16733 \| MGC102720 \| NR2B1	retinoid X receptor, alpha	-	HPRD	8622986
SIN3A	DKFZp434K2235 \| FLJ90319 \| KIAA0700	SIN3 homolog A, transcription regulator (yeast)	-	HPRD	9627120 \|11719366
SIN3A	DKFZp434K2235 \| FLJ90319 \| KIAA0700	SIN3 homolog A, transcription regulator (yeast)	Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	9627120 \|9765306 \|11719366
SIN3A	DKFZp434K2235 \| FLJ90319 \| KIAA0700	SIN3 homolog A, transcription regulator (yeast)	Sin3A interacts with PLZF. This interaction was modelled on a demonstrated interaction between mSin3A and PLZF from unspecified species.	BIND	9486654
SIN3B	KIAA0700	SIN3 homolog B, transcription regulator (yeast)	-	HPRD,BioGRID	9627120
SP1	-	Sp1 transcription factor	-	HPRD	12004059
SPOP	TEF2	speckle-type POZ protein	Two-hybrid	BioGRID	16189514
TERF1	FLJ41416 \| PIN2 \| TRBF1 \| TRF \| TRF1 \| hTRF1-AS \| t-TRF1	telomeric repeat binding factor (NIMA-interacting) 1	Two-hybrid	BioGRID	16169070
THNSL2	FLJ10916 \| THS2 \| TSH2	threonine synthase-like 2 (S. cerevisiae)	Two-hybrid	BioGRID	16169070
TOLLIP	FLJ33531 \| IL-1RAcPIP	toll interacting protein	Two-hybrid	BioGRID	16169070
TRAF2	MGC:45012 \| TRAP \| TRAP3	TNF receptor-associated factor 2	Two-hybrid	BioGRID	16189514
TRIM27	RFP \| RNF76	tripartite motif-containing 27	Two-hybrid	BioGRID	16189514
TXNIP	EST01027 \| HHCPA78 \| THIF \| VDUP1	thioredoxin interacting protein	-	HPRD,BioGRID	12821938
VDR	NR1I1	vitamin D (1,25- dihydroxyvitamin D3) receptor	-	HPRD,BioGRID	11719366 \|12460926 \|14521715
VTA1	C6orf55 \| DRG-1 \| DRG1 \| FLJ27228 \| HSPC228 \| LIP5 \| My012 \| SBP1	Vps20-associated 1 homolog (S. cerevisiae)	Two-hybrid	BioGRID	16189514
WDR33	FLJ11294 \| WDC146	WD repeat domain 33	Two-hybrid	BioGRID	16169070
ZBTB16	PLZF \| ZNF145	zinc finger and BTB domain containing 16	-	HPRD,BioGRID	8622986
ZBTB32	FAXF \| FAZF \| Rog \| TZFP \| ZNF538	zinc finger and BTB domain containing 32	-	HPRD,BioGRID	10572087
ZNF24	KOX17 \| RSG-A \| ZNF191 \| ZSCAN3 \| Zfp191	zinc finger protein 24	Two-hybrid	BioGRID	16169070

Section V. Pathway annotation

Pathway name	Pathway size	# SZGR 2.0 genes in pathway	Info
KEGG PATHWAYS IN CANCER	328	259	All SZGR 2.0 genes in this pathway
KEGG ACUTE MYELOID LEUKEMIA	60	47	All SZGR 2.0 genes in this pathway
BIOCARTA EGFR SMRTE PATHWAY	11	11	All SZGR 2.0 genes in this pathway
REACTOME IMMUNE SYSTEM	933	616	All SZGR 2.0 genes in this pathway
REACTOME ADAPTIVE IMMUNE SYSTEM	539	350	All SZGR 2.0 genes in this pathway
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION	251	156	All SZGR 2.0 genes in this pathway
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	212	129	All SZGR 2.0 genes in this pathway
TURASHVILI BREAST DUCTAL CARCINOMA VS LOBULAR NORMAL DN	69	43	All SZGR 2.0 genes in this pathway
CHARAFE BREAST CANCER LUMINAL VS BASAL DN	455	304	All SZGR 2.0 genes in this pathway
DOANE RESPONSE TO ANDROGEN UP	184	125	All SZGR 2.0 genes in this pathway
GRABARCZYK BCL11B TARGETS UP	81	40	All SZGR 2.0 genes in this pathway
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION HSC DN	187	115	All SZGR 2.0 genes in this pathway
HAHTOLA SEZARY SYNDROM DN	42	26	All SZGR 2.0 genes in this pathway
HAHTOLA MYCOSIS FUNGOIDES DN	16	10	All SZGR 2.0 genes in this pathway
ENK UV RESPONSE EPIDERMIS DN	508	354	All SZGR 2.0 genes in this pathway
CHEBOTAEV GR TARGETS UP	77	62	All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY SERUM DEPRIVATION DN	234	147	All SZGR 2.0 genes in this pathway
MARTIN INTERACT WITH HDAC	44	31	All SZGR 2.0 genes in this pathway
MYLLYKANGAS AMPLIFICATION HOT SPOT 23	24	13	All SZGR 2.0 genes in this pathway
FARMER BREAST CANCER APOCRINE VS BASAL	330	217	All SZGR 2.0 genes in this pathway
MARTORIATI MDM4 TARGETS FETAL LIVER UP	227	137	All SZGR 2.0 genes in this pathway
GOUYER TATI TARGETS UP	10	7	All SZGR 2.0 genes in this pathway
BENPORATH SUZ12 TARGETS	1038	678	All SZGR 2.0 genes in this pathway
BENPORATH EED TARGETS	1062	725	All SZGR 2.0 genes in this pathway
BENPORATH ES WITH H3K27ME3	1118	744	All SZGR 2.0 genes in this pathway
BENPORATH PRC2 TARGETS	652	441	All SZGR 2.0 genes in this pathway
ONDER CDH1 TARGETS 2 UP	256	159	All SZGR 2.0 genes in this pathway
ONDER CDH1 TARGETS 1 UP	140	85	All SZGR 2.0 genes in this pathway
ONDER CDH1 TARGETS 3 UP	17	11	All SZGR 2.0 genes in this pathway
CERVERA SDHB TARGETS 1 DN	38	22	All SZGR 2.0 genes in this pathway
LE EGR2 TARGETS DN	108	84	All SZGR 2.0 genes in this pathway
FERRANDO LYL1 NEIGHBORS	15	12	All SZGR 2.0 genes in this pathway
SANSOM APC TARGETS UP	126	84	All SZGR 2.0 genes in this pathway
SANSOM APC TARGETS DN	366	238	All SZGR 2.0 genes in this pathway
WANG IMMORTALIZED BY HOXA9 AND MEIS1 DN	24	15	All SZGR 2.0 genes in this pathway
MATSUDA NATURAL KILLER DIFFERENTIATION	475	313	All SZGR 2.0 genes in this pathway
YAGI AML FAB MARKERS	191	131	All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE UP	1691	1088	All SZGR 2.0 genes in this pathway
CHEN LVAD SUPPORT OF FAILING HEART UP	103	69	All SZGR 2.0 genes in this pathway
BURTON ADIPOGENESIS 4	48	32	All SZGR 2.0 genes in this pathway
LEE CALORIE RESTRICTION NEOCORTEX DN	88	58	All SZGR 2.0 genes in this pathway
VARELA ZMPSTE24 TARGETS UP	40	30	All SZGR 2.0 genes in this pathway
SARTIPY NORMAL AT INSULIN RESISTANCE DN	21	11	All SZGR 2.0 genes in this pathway
SARRIO EPITHELIAL MESENCHYMAL TRANSITION DN	154	101	All SZGR 2.0 genes in this pathway
RIGGI EWING SARCOMA PROGENITOR UP	430	288	All SZGR 2.0 genes in this pathway
SMID BREAST CANCER LUMINAL A UP	84	52	All SZGR 2.0 genes in this pathway
SMID BREAST CANCER BASAL DN	701	446	All SZGR 2.0 genes in this pathway
BONOME OVARIAN CANCER POOR SURVIVAL UP	31	22	All SZGR 2.0 genes in this pathway
BONOME OVARIAN CANCER SURVIVAL SUBOPTIMAL DEBULKING	510	309	All SZGR 2.0 genes in this pathway
MATZUK SPERMATOGONIA	24	17	All SZGR 2.0 genes in this pathway
BOQUEST STEM CELL CULTURED VS FRESH UP	425	298	All SZGR 2.0 genes in this pathway
GRESHOCK CANCER COPY NUMBER UP	323	240	All SZGR 2.0 genes in this pathway
BOYLAN MULTIPLE MYELOMA C D DN	252	155	All SZGR 2.0 genes in this pathway
SWEET LUNG CANCER KRAS DN	435	289	All SZGR 2.0 genes in this pathway
SHEDDEN LUNG CANCER GOOD SURVIVAL A4	196	124	All SZGR 2.0 genes in this pathway
MIKKELSEN MCV6 HCP WITH H3K27ME3	435	318	All SZGR 2.0 genes in this pathway
BOYLAN MULTIPLE MYELOMA PCA1 UP	101	66	All SZGR 2.0 genes in this pathway
HAHTOLA CTCL CUTANEOUS	26	19	All SZGR 2.0 genes in this pathway
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 8	49	36	All SZGR 2.0 genes in this pathway
MARTENS BOUND BY PML RARA FUSION	456	287	All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN	1972	1213	All SZGR 2.0 genes in this pathway
LEE BMP2 TARGETS UP	745	475	All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY	1839	928	All SZGR 2.0 genes in this pathway

Gene Page: ZBTB16