Gene Page: BTG2

Summary ?
GeneID7832
SymbolBTG2
SynonymsPC3|TIS21
DescriptionBTG family member 2
ReferenceMIM:601597|HGNC:HGNC:1131|Ensembl:ENSG00000159388|HPRD:03357|Vega:OTTHUMG00000035834
Gene typeprotein-coding
Map location1q32
Sherlock p-value0.484
Fetal beta-0.259
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophreniasClick to show details

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs697455chr1202512075BTG278320.18cis
rs12059674chr157630277BTG278320trans
rs17100274chr177774412BTG278320.13trans
rs1796829chr1239661818BTG278320.15trans
rs12034521chr1239717679BTG278320trans
snp_a-19903540BTG278322.022E-4trans
rs17038084chr285192280BTG278320.02trans
rs17498115chr285249294BTG278320.18trans
rs6707117chr2136855504BTG278320trans
snp_a-21983630BTG278320.04trans
rs2875492chr386006209BTG278320.01trans
rs9288980chr3112964991BTG278320.08trans
rs3995908chr3112998529BTG278320.08trans
rs7652801chr3113008605BTG278320.08trans
rs4631023chr48101794BTG278320.2trans
rs10040715chr557594207BTG278320trans
rs16894149chr561013724BTG278320trans
snp_a-42173000BTG278323.675E-4trans
rs2141482chr5136760477BTG278320.14trans
rs2189803chr5137684661BTG278328.295E-8trans
rs2237175chr616573534BTG278320.14trans
rs10945911chr6164047509BTG278320.03trans
rs1419793chr734697630BTG278320.07trans
rs2199402chr89201002BTG278320.1trans
rs1381350chr89217194BTG278320.04trans
rs7841407chr89243427BTG278320.11trans
rs1733950chr890062516BTG278320.03trans
rs318307chr890185459BTG278320.06trans
rs9298651chr910076275BTG278320.02trans
rs16931013chr910076859BTG278320.02trans
rs16931018chr910077048BTG278320.02trans
rs6537944chr9137312827BTG278320.09trans
rs4149623chr126450577BTG278320.1trans
rs2856339chr1211906818BTG278320.09trans
rs8490chr1251453904BTG278320.08trans
rs4905035chr1493489262BTG278325.32E-4trans
rs941539chr1493561214BTG278320.04trans
rs17128893chr1493615606BTG278320.2trans
rs1885073chr14104357181BTG278326.448E-4trans
rs8047151chr1617209696BTG278320.1trans
rs5768165chr2248318197BTG278320.02trans
rs5768168chr2248319334BTG278320.02trans
rs5768173chr2248321475BTG278320.02trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
PID P53 DOWNSTREAM PATHWAY 13794All SZGR 2.0 genes in this pathway
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS UP 579346All SZGR 2.0 genes in this pathway
GARY CD5 TARGETS UP 473314All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE LIVE UP 485293All SZGR 2.0 genes in this pathway
HUTTMANN B CLL POOR SURVIVAL UP 276187All SZGR 2.0 genes in this pathway
DIAZ CHRONIC MEYLOGENOUS LEUKEMIA DN 11679All SZGR 2.0 genes in this pathway
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP 233161All SZGR 2.0 genes in this pathway
LOPEZ MESOTELIOMA SURVIVAL TIME DN 77All SZGR 2.0 genes in this pathway
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION MONOCYTE DN 5438All SZGR 2.0 genes in this pathway
SENESE HDAC3 TARGETS UP 501327All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE FIMA UP 544308All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE LPS UP 431237All SZGR 2.0 genes in this pathway
HAHTOLA MYCOSIS FUNGOIDES CD4 UP 6446All SZGR 2.0 genes in this pathway
KOKKINAKIS METHIONINE DEPRIVATION 48HR UP 12895All SZGR 2.0 genes in this pathway
KOKKINAKIS METHIONINE DEPRIVATION 96HR UP 11784All SZGR 2.0 genes in this pathway
GESERICK TERT TARGETS DN 2116All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN UP 1142669All SZGR 2.0 genes in this pathway
GRAESSMANN RESPONSE TO MC AND DOXORUBICIN UP 612367All SZGR 2.0 genes in this pathway
GAUSSMANN MLL AF4 FUSION TARGETS F UP 185119All SZGR 2.0 genes in this pathway
KERLEY RESPONSE TO CISPLATIN UP 4430All SZGR 2.0 genes in this pathway
PEREZ TP53 TARGETS 1174695All SZGR 2.0 genes in this pathway
RASHI RESPONSE TO IONIZING RADIATION 2 12792All SZGR 2.0 genes in this pathway
RASHI NFKB1 TARGETS 1918All SZGR 2.0 genes in this pathway
FARMER BREAST CANCER APOCRINE VS LUMINAL 326213All SZGR 2.0 genes in this pathway
LUI THYROID CANCER CLUSTER 1 5133All SZGR 2.0 genes in this pathway
DIRMEIER LMP1 RESPONSE EARLY 6648All SZGR 2.0 genes in this pathway
AMUNDSON DNA DAMAGE RESPONSE TP53 169All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 UP 309199All SZGR 2.0 genes in this pathway
MARTORIATI MDM4 TARGETS FETAL LIVER UP 227137All SZGR 2.0 genes in this pathway
BORLAK LIVER CANCER EGF UP 5741All SZGR 2.0 genes in this pathway
TSAI RESPONSE TO IONIZING RADIATION 149101All SZGR 2.0 genes in this pathway
SHETH LIVER CANCER VS TXNIP LOSS PAM2 153102All SZGR 2.0 genes in this pathway
SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN DN 584395All SZGR 2.0 genes in this pathway
KHETCHOUMIAN TRIM24 TARGETS UP 4738All SZGR 2.0 genes in this pathway
FALVELLA SMOKERS WITH LUNG CANCER 8052All SZGR 2.0 genes in this pathway
AMIT DELAYED EARLY GENES 1815All SZGR 2.0 genes in this pathway
PASQUALUCCI LYMPHOMA BY GC STAGE UP 283177All SZGR 2.0 genes in this pathway
BENPORATH SUZ12 TARGETS 1038678All SZGR 2.0 genes in this pathway
BENPORATH EED TARGETS 1062725All SZGR 2.0 genes in this pathway
BENPORATH ES WITH H3K27ME3 1118744All SZGR 2.0 genes in this pathway
BENPORATH PRC2 TARGETS 652441All SZGR 2.0 genes in this pathway
AMIT EGF RESPONSE 20 HELA 118All SZGR 2.0 genes in this pathway
AMIT EGF RESPONSE 40 HELA 4229All SZGR 2.0 genes in this pathway
WANG PROSTATE CANCER ANDROGEN INDEPENDENT 6637All SZGR 2.0 genes in this pathway
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP 223140All SZGR 2.0 genes in this pathway
MORI PRE BI LYMPHOCYTE DN 7749All SZGR 2.0 genes in this pathway
MORI SMALL PRE BII LYMPHOCYTE UP 8657All SZGR 2.0 genes in this pathway
ONDER CDH1 TARGETS 1 UP 14085All SZGR 2.0 genes in this pathway
ROZANOV MMP14 TARGETS UP 266171All SZGR 2.0 genes in this pathway
SHEPARD CRUSH AND BURN MUTANT UP 197110All SZGR 2.0 genes in this pathway
PENG LEUCINE DEPRIVATION UP 14293All SZGR 2.0 genes in this pathway
KANNAN TP53 TARGETS UP 5840All SZGR 2.0 genes in this pathway
LEE LIVER CANCER MYC TGFA UP 6140All SZGR 2.0 genes in this pathway
KLEIN PRIMARY EFFUSION LYMPHOMA DN 5842All SZGR 2.0 genes in this pathway
TARTE PLASMA CELL VS PLASMABLAST UP 398262All SZGR 2.0 genes in this pathway
PEART HDAC PROLIFERATION CLUSTER UP 5735All SZGR 2.0 genes in this pathway
JECHLINGER EPITHELIAL TO MESENCHYMAL TRANSITION DN 6647All SZGR 2.0 genes in this pathway
VANTVEER BREAST CANCER METASTASIS UP 5631All SZGR 2.0 genes in this pathway
PENG RAPAMYCIN RESPONSE UP 203130All SZGR 2.0 genes in this pathway
HESS TARGETS OF HOXA9 AND MEIS1 DN 7748All SZGR 2.0 genes in this pathway
LENAOUR DENDRITIC CELL MATURATION DN 12890All SZGR 2.0 genes in this pathway
HADDAD B LYMPHOCYTE PROGENITOR 293193All SZGR 2.0 genes in this pathway
GERY CEBP TARGETS 12690All SZGR 2.0 genes in this pathway
BASSO CD40 SIGNALING DN 6844All SZGR 2.0 genes in this pathway
PETROVA ENDOTHELIUM LYMPHATIC VS BLOOD DN 162102All SZGR 2.0 genes in this pathway
AFFAR YY1 TARGETS UP 214133All SZGR 2.0 genes in this pathway
TAVOR CEBPA TARGETS UP 4836All SZGR 2.0 genes in this pathway
BRACHAT RESPONSE TO CISPLATIN 2211All SZGR 2.0 genes in this pathway
GENTILE UV LOW DOSE UP 2719All SZGR 2.0 genes in this pathway
MCDOWELL ACUTE LUNG INJURY UP 4529All SZGR 2.0 genes in this pathway
ZHANG RESPONSE TO CANTHARIDIN UP 1912All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE UP 16911088All SZGR 2.0 genes in this pathway
CHEN LVAD SUPPORT OF FAILING HEART UP 10369All SZGR 2.0 genes in this pathway
BRACHAT RESPONSE TO METHOTREXATE UP 2616All SZGR 2.0 genes in this pathway
EHRLICH ICF SYNDROM DN 1513All SZGR 2.0 genes in this pathway
BRACHAT RESPONSE TO CAMPTOTHECIN UP 2818All SZGR 2.0 genes in this pathway
BURTON ADIPOGENESIS PEAK AT 2HR 5136All SZGR 2.0 genes in this pathway
VARELA ZMPSTE24 TARGETS UP 4030All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 1 528324All SZGR 2.0 genes in this pathway
GAVIN FOXP3 TARGETS CLUSTER T4 9469All SZGR 2.0 genes in this pathway
RIGGI EWING SARCOMA PROGENITOR UP 430288All SZGR 2.0 genes in this pathway
SMID BREAST CANCER LUMINAL A UP 8452All SZGR 2.0 genes in this pathway
SMID BREAST CANCER BASAL DN 701446All SZGR 2.0 genes in this pathway
KUMAMOTO RESPONSE TO NUTLIN 3A UP 95All SZGR 2.0 genes in this pathway
BONCI TARGETS OF MIR15A AND MIR16 1 9175All SZGR 2.0 genes in this pathway
BOQUEST STEM CELL CULTURED VS FRESH UP 425298All SZGR 2.0 genes in this pathway
WEST ADRENOCORTICAL TUMOR DN 546362All SZGR 2.0 genes in this pathway
WANG TUMOR INVASIVENESS DN 210128All SZGR 2.0 genes in this pathway
CHAUHAN RESPONSE TO METHOXYESTRADIOL DN 10265All SZGR 2.0 genes in this pathway
ICHIBA GRAFT VERSUS HOST DISEASE 35D UP 13179All SZGR 2.0 genes in this pathway
LEE DIFFERENTIATING T LYMPHOCYTE 200115All SZGR 2.0 genes in this pathway
ZHANG TLX TARGETS 36HR UP 221150All SZGR 2.0 genes in this pathway
ZHANG TLX TARGETS 60HR UP 293203All SZGR 2.0 genes in this pathway
ZHANG TLX TARGETS UP 10878All SZGR 2.0 genes in this pathway
SHEDDEN LUNG CANCER GOOD SURVIVAL A12 317177All SZGR 2.0 genes in this pathway
HSIAO HOUSEKEEPING GENES 389245All SZGR 2.0 genes in this pathway
MILI PSEUDOPODIA HAPTOTAXIS DN 668419All SZGR 2.0 genes in this pathway
KYNG WERNER SYNDROM AND NORMAL AGING UP 9362All SZGR 2.0 genes in this pathway
WONG ADULT TISSUE STEM MODULE 721492All SZGR 2.0 genes in this pathway
CHANDRAN METASTASIS DN 306191All SZGR 2.0 genes in this pathway
MARTENS TRETINOIN RESPONSE UP 857456All SZGR 2.0 genes in this pathway
DUTERTRE ESTRADIOL RESPONSE 24HR DN 505328All SZGR 2.0 genes in this pathway
WIERENGA STAT5A TARGETS UP 217131All SZGR 2.0 genes in this pathway
WIERENGA STAT5A TARGETS GROUP2 6038All SZGR 2.0 genes in this pathway
BHAT ESR1 TARGETS NOT VIA AKT1 DN 8861All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE VIA TP53 GROUP B 549316All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE MIDDLE 9856All SZGR 2.0 genes in this pathway
PASINI SUZ12 TARGETS DN 315215All SZGR 2.0 genes in this pathway
FEVR CTNNB1 TARGETS UP 682433All SZGR 2.0 genes in this pathway
KOINUMA TARGETS OF SMAD2 OR SMAD3 824528All SZGR 2.0 genes in this pathway
JUBAN TARGETS OF SPI1 AND FLI1 UP 11573All SZGR 2.0 genes in this pathway
SMIRNOV RESPONSE TO IR 6HR UP 16697All SZGR 2.0 genes in this pathway
WARTERS RESPONSE TO IR SKIN 8344All SZGR 2.0 genes in this pathway
WARTERS IR RESPONSE 5GY 4723All SZGR 2.0 genes in this pathway
ZWANG DOWN BY 2ND EGF PULSE 293119All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY 1839928All SZGR 2.0 genes in this pathway