Found 84 literature records

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Entrez ID	Description
5920	"Expression of a retinoid-inducible tumor suppressor, Tazarotene-inducible gene-3, is decreased in psoriasis and skin cancer."
324	Upstream stimulating factor-1 (USF1) and USF2 bind to and activate the promoter of the adenomatous polyposis coli (APC) tumor suppressor gene.
9077	Genomic structure and promoter characterization of an imprinted tumor suppressor gene ARHI.
7249	Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM).
4763	NF1 tumor suppressor may function in the regulation of epidermal histogenesis via controlling the organization of the keratin cytoskeleton during the assembly of desmosomes and hemidesmosomes.
2810	Stratifin was first identified as an epithelial cell antigen exclusively expressed in epithelia. the functional role of sfn in cell proliferation and apoptosis could be relevant to the regulation of growth and differentiation as a tumor suppressor gene
4851	Notch1 functions as a tumor suppressor in mouse skin.
1452	"2 proteins reported to function in Wingless(Wg) signaling identified as Hh pathway components: Dally-like protein required for Hh signal reception, and casein kinase 1alpha, a candidate tumor suppressor that regulates activities of both Hh and Wg pathways"
7249	Up-regulation of hypoxia-inducible factor 2alpha in renal cell carcinoma is associated with loss of Tsc-2 tumor suppressor gene.
857	Results provide the first genetic evidence that caveolin-1 indeed functions as a tumor suppressor gene in vivo.
5920	A novel tumor suppressor protein promotes keratinocyte terminal differentiation via activation of type I transglutaminase.
5727	Developmental defects in Gorlin syndrome related to a putative tumor suppressor gene on chromosome 9.
4771	"Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1."
5727	Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site.
3659	Functional role for IRF-1 in the growth suppression of breast cancer cells and strongly implicate IRF-1 as a tumor suppressor gene in breast cancer that act to control apoptosis.
5728	The soy isoflavone genistein promotes apoptosis in mammary epithelial cells by inducing the tumor suppressor PTEN.
27075	NET-6 may represent a novel breast cancer suppressor gene.
5325	The candidate tumor suppressor gene ZAC is involved in keratinocyte differentiation and its expression is lost in basal cell carcinomas.
5925	data show that E2F1 has potential binding activity to the retinoblastoma control element and a different transcriptional regulation pathway which cooperates with the retinoblastoma tumor suppressor protein
23513	These results suggest that Scrib stabilizes the coupling between E-cadherin and the catenins and are consistent with the idea that mammalian Scrib could behave as a tumor suppressor by regulating epithelial cell adhesion and migration.
25833	"POU2F3 in cervical cancer cells may be CC-related tumor suppressor genes, which are disrupted by both epigenetic and genetic mechanisms."
324	The adenomatous polyposis coli tumor suppressor gene regulates expression of cyclooxygenase-2 by a mechanism that involves retinoic acid.
27316	hnRNP G is a tumor suppressor against HOSCC but its mechanisms of action remain to be further investigated
301	"Annexin I may have tumor suppressor functions in prostate cancer. The pro-apoptotic effect of ANX I involves the activation of p38 and JNK, which appears to shift the balance of signal transduction away from proliferation and toward apoptosis."
2697	"Cx43 plays a role as a tumor suppressor, however, no definite correlation was found between Cx43 and cell migration and invasion."
23705	Tumor suppressor in lung cancer-1 as a novel ameloblast adhesion molecule and its downregulation in ameloblastoma.
79577	These experiments identify for the first time a proapoptotic activity of endogenous parafibromin likely to be important in its role as a tumor suppressor and show a functional role for the NLS of parafibromin in this activity.
3621	Phosphorylation of the tumor suppressor p33(ING1b) at Ser-126 influences its protein stability and proliferation of melanoma cells.
7157	p53 is a direct transcriptional target gene of hPitx1. This observation is concordant with the recent identification of hPitx1 as a tumor suppressor gene.
2903	NMDAR2A is commonly hypermethylated in primary human colorectal carcinoma and possesses tumor-suppressive activity.
5728	Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair.
1029	A non-tumor suppressor role for basal p19ARF in maintaining nucleolar structure and function.
4851	"in UV-related squamous cell photocarcinogenesis Notch 1 downregulation could mirror a tumor suppressor function of the receptor, in sun-protected squamous cell carcinomas Notch 1 was upregulated"
580	"The remarkable similarities between the mammary carcinomas of Bard1-, Brca1-, and Bard1/Brca1-mutant mice indicate that the tumor suppressor activities of both genes are mediated through the BRCA1/BARD1 heterodimer."
672	"The remarkable similarities between the mammary carcinomas of Bard1-, Brca1-, and Bard1/Brca1-mutant mice indicate that the tumor suppressor activities of both genes are mediated through the BRCA1/BARD1 heterodimer."
3685	alphav integrins play a tumor suppressor-like function.
5728	VHL mutation alone is insufficient for tumor formation; study shows that epididymal cystadenomas from VHL patients frequently also lack expression of the PTEN tumor suppressor and display activation of phosphatidylinositol 3-kinase pathway signaling.
7428	VHL mutation alone is insufficient for tumor formation; study shows that epididymal cystadenomas from VHL patients frequently also lack expression of the PTEN tumor suppressor and display activation of phosphatidylinositol 3-kinase pathway signaling.
7157	"The existence of a functional binding site for the tumor suppressor p53 near the proximal CCAAT box and the fact that the basal expression of annexin A1 in human colon adenocarcinoma cells is driven by p53 at the transcriptional level, is shown."
2137	Exostoses like-3 (EXTL3) is a putative tumour suppressor gene.
5727	Heterozygous mutations in the tumor suppressor gene PATCHED provoke basal cell carcinoma-like features in human organotypic skin cultures.
51147	The ING4 tumor suppressor attenuates NF-kappaB activity at the promoters of target genes.
5727	Tumor suppressor gene co-operativity in compound Patched1 and suppressor of fused heterozygous mutant mice.
7157	"In this immunohistochemical study, 80% of all vulvar intra-epithelial neoplasia were negative for p53 tumor suppressor protein."
8711	Tnk1/Kos1 is a tumor suppressor that functions to down-regulate Ras activity
7832	Estradiol downregulation of the tumor suppressor gene BTG2 requires estrogen receptor-alpha and the REA corepressor
5371	The tumor suppressor Pml regulates cell fate in the developing neocortex.
5925	The tumor suppressor Pml regulates cell fate in the developing neocortex.
4771	Identification of erythrocyte p55/MPP1 as a binding partner of NF2 tumor suppressor protein/Merlin.
1050	In prostate cancer cells C/EBPalpha cannot function as a tumor suppressor

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