Found 484 literature records

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Entrez ID	Description
3622	"Cloning of a novel gene (ING1L) homologous to ING1, a candidate tumor suppressor."
1801	"Expression of OVCA1, a candidate tumor suppressor, is reduced in tumors and inhibits growth of ovarian cancer cells."
4763	Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo.
324	Crystal structure of the amino-terminal coiled-coil domain of the APC tumor suppressor.
324	"Asef, a link between the tumor suppressor APC and G-protein signaling."
6477	Lack of somatic mutation in the coding sequence of SIAH1 in tumors hemizygous for this candidate tumor suppressor gene.
5920	"The carboxy-terminal hydrophobic domain of TIG3, a class II tumor suppressor protein, is required for appropriate cellular localization and optimal biological activity."
324	Apical membrane localization of the adenomatous polyposis coli tumor suppressor protein and subcellular distribution of the beta-catenin destruction complex in polarized epithelial cells.
8915	These data suggest that wild-type BCL10 may act as a tumor suppressor.
4763	"Neurofibromin, a tumor suppressor in the nervous system."
857	"Down-regulation of caveolin-1, a candidate tumor suppressor gene, in sarcomas."
1029	"The human tumor suppressor arf interacts with spinophilin/neurabin II, a type 1 protein-phosphatase-binding protein."
7982	Mutational and functional analyses reveal that ST7 is a highly conserved tumor-suppressor gene on human chromosome 7q31.
310	"ANX7, a candidate tumor suppressor gene for prostate cancer."
5325	Alternative splicing of the imprinted candidate tumor suppressor gene ZAC regulates its antiproliferative and DNA binding activities.
11186	"The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis."
11178	Functional identification of LZTS1 as a candidate prostate tumor suppressor gene on human chromosome 8p22.
2131	The link between heparan sulfate and hereditary bone disease: finding a function for the EXT family of putative tumor suppressor proteins.
11334	Overexpression of candidate tumor suppressor geneFUS1 isolated from the 3p21.3 homozygous deletionregion leads to G1 arrest and growth inhibition oflung cancer cells.
7869	Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B.
7799	"Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily."
27086	The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p.
1050	may function as a tumor suppressor that is mutated during tumorigenesis. Abnormalties in C/EBPalpha function contribute to the development of malignancies in a variety of tisues.
5728	Motif analysis of the tumor suppressor gene MMAC/PTEN identifies tyrosines critical for tumor suppression and lipid phosphatase activity.
8838	"WISP3 acts as a tumor suppressor gene in the breast. Loss of WISP3 expression contributes to the phenotype of IBC by regulating tumor cell growth, invasion and angiogenesis."
863	CBFA2T3 (MTG16) is a putative breast tumor suppressor gene from the breast cancer loss of heterozygosity region at 16q24.3.
7020	Results indicate that the tumor suppressor activity of AP2alpha is mediated through a direct interaction with p53.
688	A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer.
9353	"SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers."
3728	function as an inhibitor of beta-catenin/TCF-dependent gene transcription and role as a potentially novel tumor suppressor protein in a subset of human NSCLC cancers
4507	"Methylthioadenosine phosphorylase, a gene frequently codeleted with p16(cdkN2a/ARF), acts as a tumor suppressor in a breast cancer cell line."
7490	Role of the WT1 tumor suppressor in normal hematopoiesis in embryo and adult cell lineages.
1500	roles of p120 as a tumor suppressor or metastasis promoter are discussed (review)
10395	"Genomic deletion of DLC-1 was observed in 40% of breast tumors, whereas reduced levels of DLC-1 mRNA were seen in 70% of breast, 70% of colon, 50% of prostate tumor cell lines.DLC-1 gene plays a role in breast cancer by acting as a tumor suppressor gene"
6598	INI1 is a tumor suppressor gene gone awry in malignant rhabdoid tumor cells
3661	"hIRF3 inhibited cell growth, blocked DNA synthesis, and induced apoptosis, while a dominant negative mutant transformed 3T3 cells, implying that IRF3 may function as a tumor suppressor and its dominant negative mutant may have a role in tumorigenesis."
665	"Analysis of the candidate 8p21 tumour suppressor, BNIP3L, in breast and ovarian cancer."
9353	SLIT2 is an excellent candidate tumor suppressor gene for colorectal cancer.
2120	"Small ubiquitin-like modifier conjugation regulates nuclear export of TEL, a putative tumor suppressor."
7157	"EGR1 as a major regulator of cell senescence and previously undescribed upstream ""gatekeeper"" of the p53 tumor suppressor pathway."
10395	"Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers."
688	Gene deletion and loss of expression and cell growth suppression indicate that KLF5 may be tumor suppressor gene at 13q21 in prostate cancer. Mutation and promoter methylation do not commonly inactivate KLF5 in prostate cancer.
8406	"down-regulation of drs mRNA is closely correlated with carcinomas which arise from adenomatous polyps in the course of the adenoma-carcinoma sequence, but most carcinomas arising de novo are independent of the tumor suppressor function of the drs gene"
137075	"characterization of CLDN23 gene, a candidate tumor suppressor gene implicated in intestinal-type gastric cancer"
10395	"DNA variants of DLC-1, a candidate tumor suppressor gene in human hepatocellular carcinoma."
160728	"SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers."
5920	"Induction of TIG3, a putative class II tumor suppressor gene, by retinoic acid in head and neck and lung carcinoma cells and its association with suppression of the transformed phenotype."
2120	"TEL, a putative tumor suppressor, induces apoptosis and represses transcription of Bcl-XL."
27113	"PUMA suppresses tumor cell growth in head/neck cancer, but it does not appear to be a direct target of inactivation in head and neck tumorigenesis."
4763	Evaluation of NF2 and NF1 tumor suppressor genes in distinctive gastrointestinal nerve sheath tumors traditionally diagnosed as benign schwannomas: s study of 20 cases.

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