Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase

Found 463 literature records

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Entrez IDDescription
9940"Molecular cloning of a candidate tumor suppressor gene, DLC1, from chromosome 3p21.3."
7157"Alterations of oncogenes, tumor suppressor genes and growth factors in hepatocellular carcinoma: with relation to tumor size and invasiveness."
11108"PFM1 (PRDM4), a new member of the PR-domain family, maps to a tumor suppressor locus on human chromosome 12q23-q24.1. These results suggest a role for PFM1 in cell differentiation and tumor suppression, remarkably consistent with the known functions of the PR-domain family."
29998A transcript map of the chromosome 19q-arm glioma tumor suppressor region.
7428The von Hippel-Lindau tumor suppressor targets to mitochondria.
23136"Loss of DAL-1, a protein 4.1-related tumor suppressor, is an important early event in the pathogenesis of meningiomas."
1029Tumor suppressor INK4: refinement of p16INK4A structure and determination of p15INK4B structure by comparative modeling and NMR data.
1030Tumor suppressor INK4: refinement of p16INK4A structure and determination of p15INK4B structure by comparative modeling and NMR data.
324Crystal structure of the amino-terminal coiled-coil domain of the APC tumor suppressor.
634"C-CAM1, a candidate tumor suppressor gene, is abnormally expressed in primary lung cancers."
324Genomic rearrangements of the APC tumor-suppressor gene in familial adenomatous polyposis.
53353"Genomic organization of a new candidate tumor suppressor gene, LRP1B."
10641The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium.
11186The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium.
11334The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium.
51364The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium.
7869The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium.
324Apical membrane localization of the adenomatous polyposis coli tumor suppressor protein and subcellular distribution of the beta-catenin destruction complex in polarized epithelial cells.
7428Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor.
23705TSLC1 is a tumor-suppressor gene in human non-small-cell lung cancer.
9077Genomic structure and promoter characterization of an imprinted tumor suppressor gene ARHI.
199731"Isolation of the TSLL1 and TSLL2 genes, members of the tumor suppressor TSLC1 gene family encoding transmembrane proteins."
11334Overexpression of candidate tumor suppressor geneFUS1 isolated from the 3p21.3 homozygous deletionregion leads to G1 arrest and growth inhibition oflung cancer cells.
27086The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p.
1050may function as a tumor suppressor that is mutated during tumorigenesis. Abnormalties in C/EBPalpha function contribute to the development of malignancies in a variety of tisues.
22806"Short isoforms of Aiolos were detected at low levels in bone marrow of normal volunters, but were not overexpressed in a patient with acute T-cell leukemia. Data for unaltered Aiolos indicates tumor suppressor function."
22807Novel short isoforms of Helios are overexpressed in a patient with T-cell acute lymphoblastic leukemia and may contribute to the development of T-cell malignancies. Data for unaltered Helios indicates tumor suppressor function.
324The coiled coil region (amino acids 129-250) of the tumor suppressor protein adenomatous polyposis coli (APC). Its structure and its interaction with chromosome maintenance region 1 (Crm-1).
1029A major functional difference between the mouse and human ARF tumor suppressor proteins.
841CASP8 may function as a tumor suppressor gene in neuroendocrine lung tumors.
84700"MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer"
23136"TSLC1 and DAL-1, two distinct tumor suppressor proteins, directly associate in lung cancer."
23705"Identification of the Tslc1 gene, a mouse orthologue of the human tumor suppressor TSLC1 gene."
9353"SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers."
8125regulatory roles of oncoprotein ProT and tumor suppressor PHAP in apoptosis
6595This report provides supportive evidence that BRG1 and BRM act as tumor suppressor proteins and implicates a role for their loss in the development of non-small cell lung cancers.
6597This report provides supportive evidence that BRG1 and BRM act as tumor suppressor proteins and implicates a role for their loss in the development of non-small cell lung cancers.
4089Activation of transforming growth factor-beta signaling by SUMO-1 modification of tumor suppressor Smad4/DPC4.
2120"Small ubiquitin-like modifier conjugation regulates nuclear export of TEL, a putative tumor suppressor."
688Gene deletion and loss of expression and cell growth suppression indicate that KLF5 may be tumor suppressor gene at 13q21 in prostate cancer. Mutation and promoter methylation do not commonly inactivate KLF5 in prostate cancer.
4771NF2 tumor suppressor gene: a comprehensive and efficient detection of somatic mutations by denaturing HPLC and microarray-CGH.
4763Complete physical map and gene content of the human NF1 tumor suppressor region in human and mouse.
8930"Finally, we have analyzed mice mutant for Mbd4 and show that this gene functions in vivo as a tumor suppressor."
7157Analyzing tumor suppressor activities in the murine small intestine.
4221Genetic ablation of the tumor suppressor menin causes lethality at mid-gestation with defects in multiple organs.
10395"DNA variants of DLC-1, a candidate tumor suppressor gene in human hepatocellular carcinoma."
11186RASSF1 is a putative tumor suppressor in non-small cell lung cancer
4089SUMO-1/Ubc9 promotes nuclear accumulation and metabolic stability of tumor suppressor Smad4.
2719These findings suggest that GPC3 is a candidate lung tumor suppressor gene whose expression may be regulated by exposure to cigarette smoke and functions to modulate cellular response to exogenous damage.
4221Multiple tumor suppressor pathways negatively regulate telomerase.


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