Found 484 literature records

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Entrez ID	Description
6925	This data support the notion that the ITF2 gene on chromosome 18q is a tumor suppressor gene.
2309	Tumor suppressor FOXO3 participates in the regulation of intestinal inflammation.
1473	Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells.
10395	"Results confirm the role of DLC1 gene as a tumor suppressor, which may be manifested by regulation of p21 and cyclinDl."
5371	Germline variants of the promyelocytic leukemia tumor suppressor gene in patients with familial cancer.
23365	LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer
2984	GUCY2C is a tumor suppressor that controls proliferation and metabolism of intestinal epithelial cells by inactivating AKT signaling
2050	The receptor tyrosine kinase EPHB4 has tumor suppressor activities in intestinal tumorigenesis.
324	The receptor tyrosine kinase EPHB4 has tumor suppressor activities in intestinal tumorigenesis.
2272	Helicobacter pylori infection and family history of gastric cancer decrease expression of FHIT tumor suppressor gene in gastric mucosa of dyspeptic patients.
112399	"PHD3 appears to be a tumor suppressor in colorectal cancer cells that inhibits IKKbeta/NF-kappaB signaling, independent of its hydroxylase activity."
406881	Let-7a microRNA functions as a potential tumor suppressor in human laryngeal cancer.
5080	Tumor suppressor PAX6 functions as androgen receptor co-repressor to inhibit prostate cancer growth.
3685	This study shows that alpha(v)beta(3)-integrin expression on tumor cells actually slows tumor progression and acts as a tumor suppressor.
3690	This study shows that alpha(v)beta(3)-integrin expression on tumor cells actually slows tumor progression and acts as a tumor suppressor.
26038	CHD5 is a tumor suppressor gene epigenetically down-regulated in gastric cancer
11197	the WIF-1 is downregulated by promoter methylation and functions as a tumor suppressor gene by inducing apoptosis in human renal cell carcinoma cells.
857	Caveolin-1 acts as a tumor suppressor by down-regulating epidermal growth factor receptor-mitogen-activated protein kinase signaling pathway in pancreatic carcinoma cell lines.
23541	Fndings raise the possibility that TAP/Sec14L2 may serve as a tumor suppressor in breast carcinogenesis.
8991	SBP1 has tumor suppressor functions that are inhibited in colorectal cancer through epigenetic silencing
5925	Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer.
23513	Tumor suppressor scribble regulates assembly of tight junctions in the intestinal epithelium.
857	"a novel function of caveolin-1 in controlling COX-2 expression, which may regulate physiological functions and have tumor suppression effects."
9368	EBP50 exerts tumor suppressor activity by promoting cell apoptosis and retarding extracellular signal-regulated kinase activity.
57447	NDRG2 is a candidate tumor-suppressor for oral squamous-cell carcinoma.
54790	It has been suggested that TET2 is a tumor suppressor gene and mutations in TET2 precede the acquisition of JAK2-V617F
7157	p53 acts as a tumor suppressor and its potential role in the outcome of antimitotic chemotherapy.
53353	Aberrant methylation impairs low density lipoprotein receptor-related protein 1B tumor suppressor function in gastric cancer.
11080	"HLJ1 switches the role of NPM1, which can act as tumor suppressor or oncogene, by modulating the oligomerization of NPM1 via HLJ1-NPM1 heterodimer formation and recruiting AP-2alpha to the MMP-2 promoter."
55384	"Therefore, these data are consistent with the hypothesis that MEG3, which encodes a noncoding RNA, may be a tumor suppressor gene at chromosome 14q32 involved in meningioma progression via a novel mechanism."
55384	MEG3 inhibits colony formation in meningioma cells. MEG3 stimulates p53-mediated transactivation in these cell lines. Data are consistent with the hypothesis that MEG3 may be a tumor suppressor gene at chromosome 14q32 involved in meningioma progression.
26136	TES gene functions as a tumor suppressor gene and is frequently silenced by hypermethylation and loss of heterozygosity in ovarian cancers.
57111	Rab25 may function as a tumor suppressor in intestinal epithelial cells through regulation of protein trafficking to the cell surface.
10395	"Synergistic antineoplastic effect of DLC1 tumor suppressor protein and histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), on prostate and liver cancer cells: perspectives for therapeutics."
6422	The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma.
6898	tumor suppressive mechanism of TAT was associated with its proapoptotic role in a mitochondrial-dependent manner by promoting cytochrome-c release and activating caspase-9 and PARP.
1473	"activation of the RhoA-ROCK-p38MAPK-MSK signaling pathway is essential for the regulation of the phenotype and of the CST5/cystatin D candidate tumor suppressor and other target genes by 1,25(OH)2D3 in colon cancer cells"
150094	"activation of the RhoA-ROCK-p38MAPK-MSK signaling pathway is essential for the regulation of the phenotype and of the CST5/cystatin D candidate tumor suppressor and other target genes by 1,25(OH)2D3 in colon cancer cells"
387	"activation of the RhoA-ROCK-p38MAPK-MSK signaling pathway is essential for the regulation of the phenotype and of the CST5/cystatin D candidate tumor suppressor and other target genes by 1,25(OH)2D3 in colon cancer cells"
84879	MFSD2A is a novel lung cancer tumor suppressor gene that regulates cell cycle progression and matrix attachment.
10181	p53 transactivation is involved in the antiproliferative activity of the putative tumor suppressor RBM5.
7157	p53 transactivation is involved in the antiproliferative activity of the putative tumor suppressor RBM5.
324	Recql5 has a tumor suppressor role in the gastrointestinal tract of Apc(min) mice.
78986	DUSP26 may function as a tumour suppressor in particular cancers.
27165	"as a unique p53 target gene, GLS2 is a mediator of p53's role in energy metabolism and antioxidant defense, which can contribute to its role in tumor suppression"
6794	"Adiponectin treatment increases the expression of tumor suppressor gene, LKB1 in breast cancer cells."
10481	"identifies several important tumor suppressors and transcription factors as direct DNMT3B targets in colon cancer and as potential biomarkers for this cancer. Further, methylation at an upstream CGI of HOXB13 is unique to colon cancer"
23582	It is proposed for the first time that Rad may promote carcinogenesis at least in part by inhibiting GCIP-mediated tumor suppression.
5728	"Microarray data revealed that 153 genes were upregulated in DNMT3A knockdown cells; 13 of them including PTEN, a crucial tumor suppressor gene in HCC, are genes involved in cell cycle and cell proliferation."
80012	PHC3 is a tumor suppressor in osteosarcoma cells abd its suppression may be caused by modification of polycomb repressive complex 1 in cancer cells.

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