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Found 41 literature records

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Entrez ID	Description
23136	"Loss of DAL-1, a protein 4.1-related tumor suppressor, is an important early event in the pathogenesis of meningiomas."
4771	Neurofibromatosis 2 (NF2) tumor suppressor schwannomin and its interacting protein HRS regulate STAT signaling.
8577	This protein may behave as a tumor suppressor gene in brain cancers.
2189	"Finally, five novel minimally deleted regions were identified in a subset of tumors, containing putative candidate tumor suppressor genes (TOPORS, FANCG, RAD51, TP53BP1, and BIK) that could have a role in gliomagenesis."
4763	A conditional allele of the NF1 tumor suppressor that negatively regulates Ras signaling together with inactivation of p53 induce malignant astrocytoma.
7157	Inactivation of p53 and a conditional allele of the NF1 tumor suppressor that negatively regulates Ras signaling induce malignant astrocytoma.
23136	The tumor suppressor DAL-1/4.1B and protein methylation cooperate in inducing apoptosis in MCF-7 breast cancer cells.
1031	The CDK inhibitor p18Ink4c is a tumor suppressor in medulloblastoma.
5727	The CDK inhibitor p18Ink4c is a tumor suppressor in medulloblastoma.
7157	The CDK inhibitor p18Ink4c is a tumor suppressor in medulloblastoma.
253738	Expression of EBF3 resulted in cell cycle arrest and apoptosis. EBF3 regulates a transcriptional program underlying a putative tumor suppression pathway.
4601	Identification and analysis of tumor suppressor loci at chromosome 10q23.3-10q25.3 in medulloblastoma.
5925	Altered structure and deregulated expression of the tumor suppressor gene retinoblastoma (RB1) in human brain tumors.
22943	Dickkopf-1 is an epigenetically silenced candidate tumor suppressor gene in medulloblastoma.
7832	PC3 / BTG2 acts as a tumor suppressor of medulloblastoma by its antiproliferative and prodifferentiative effect on cerebellar progenitors. This antagonizes Shh and appears physiologic since endogenous PC3 / BTG2 decreases in human medulloblastomas.
7832	PC3/Tis21/BTG2 is a tumor suppressor of medulloblastoma
8313	"The pathway is negatively controlled by the tumor suppressor AXIN2 (Conductin), a scaffold protein of this signaling complex."
1316	Functional inactivation of the KLF6 tumor suppressor gene by loss of heterozygosity and increased alternative splicing in glioblastoma.
7157	the human glutathione S-transferase P1 gene is a novel transcriptional target of the p53 tumor suppressor gene
10653	data support the role of SPINT2 as a putative tumor suppressor gene in medulloblastoma and further implicate dysregulation of the HGF/MET signaling pathway in the pathogenesis of medulloblastoma
51684	human tumor suppressor SUFU has a role in Hedgehog signaling [review]
4763	Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model.
5728	Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model.
7157	Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model.
1029	Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis.
5728	Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis.
10612	Loss of heterozygosity of chromosome segment 11p15.5 in malignant gliomas suggests TRIM3 as a candidate brain tumor suppressor gene.
3417	"IDH1 appears to function as a tumor suppressor that, when mutationally inactivated, contributes to tumorigenesis in part through induction of the HIF-1 pathway"
310	Haploinsufficiency of the tumor suppressor ANXA7 due to monosomy of chromosome 10 provides a clinically relevant mechanism to augment EGFR signaling in glioblastomas beyond that resulting from amplification of the EGFR gene.
406983	miR-200a appears to act as a multifunctional tumor suppressor miRNA in meningiomas through effects on the E-cadherin and Wnt/beta-catenin signaling pathways.
9314	Data show that that KLF4 is inactivated by either genetic or epigenetic mechanisms in a large subset of medulloblastomas and that it likely functions as a tumor suppressor gene in the pathogenesis of medulloblastoma.
10472	Findings indicate that ZNF238 is a novel brain tumor suppressor and its reactivation in tumors could open a novel anticancer strategy.
407040	miR-34a is a tumor suppressor.
6422	The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma.
7157	nuclear Bcl2L12 physically and functionally interacts with the p53 tumor suppressor
407010	"CREB promotes gliomagenesis and acts as a modulator of oncogenic mir-23a, which represses the tumor suppressor PTEN."
406901	"p53-induced miR-107 suppresses brain tumor cell growth and down-regulates CDK6 and Notch-2 expression, supporting its tumor suppressor role and utility as a target for glioma therapy."
406924	MiR-134 could play an important role as a tumor suppressor relying on its direct translational attenuation of Nanog
5522	PPP2R2C is a potential tumor suppressor gene in human brain cancers.
406924	Results identify miR-134 as a novel RTK-regulated tumor-suppressive hub that mediates RTK and RTK-inhibitor effects on GBM malignancy by controlling KRAS and STAT5B.
406943	miR-152 mediates the tumor-suppressive effects that knockdown of XIST exerts in glioblastoma stem cells.