DegronMD

Uniprot ID: Q7Z5P9

Source protein: Mucin-19

Source gene: MUC19

Class: DEG_SPOP_SBC_1

Location: 6335:6339

E3 ligase: SPOP

DEGRON score: 0.5654

ASA_SCORE: 86.82

COIL: 0.7276

CONS_SCORE: 0

DSS_SCORE: 0.6705

HELIX: 0.041

FCONS_SCORE: 0

RIG_SCORE: 0.6926

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Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
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Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
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Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q99504	Eyes absent homolog 3	DEG_SPOP_SBC_1	227:231	AESTT	SPOP	0.9997	More...
Q9BYW2	Histone-lysine N-methyltransferase SETD2	DEG_SPOP_SBC_1	178:182	AESTT	SPOP	0.9262	More...
Q99698	Lysosomal-trafficking regulator	DEG_SPOP_SBC_1	1487:1491	AESTT	SPOP	0.7185	More...
Q9UKN1	Mucin-12	DEG_SPOP_SBC_1	4852:4856	AESTT	SPOP	0.6629	More...
Q7Z5P9	Mucin-19	DEG_SPOP_SBC_1	6335:6339	AESTT	SPOP	0.5654	More...
O14594	Neurocan core protein	DEG_SPOP_SBC_1	854:858	AESTT	SPOP	0.7876	More...
Q9C093	Sperm flagellar protein 2	DEG_SPOP_SBC_1	548:552	AESTT	SPOP	0.8268	More...

Showing 1 to 7 of 7 entries

DegronMD: protein-targeted degradation, mutation and drug response to degrons