DegronMD - P49790(NUP153)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G1025S	TCGA-06-2564	GBM	TCGA	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation rewiring degron network	0.1667
p.G1025S	DO13378	GBM	ICGC	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation rewiring degron network	0.1667
p.G1025S	DO230998	LUSC	ICGC	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation rewiring degron network	0.1667
p.G1025S	DO224576	LUSC	ICGC	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation rewiring degron network	0.1667
p.E1012D	TCGA-06-5416	GBM	TCGA	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation rewiring degron network	0.25
p.E1012D	DO10880	GBM	ICGC	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation rewiring degron network	0.25
p.V1117D	TCGA-13-2057	OV	TCGA	PVTST	DEG_SPOP_SBC_1	1110:1114	Mutation rewiring degron network	0.25
p.V1117D	DO31320	OV	ICGC	PVTST	DEG_SPOP_SBC_1	1110:1114	Mutation rewiring degron network	0.25
p.L387M	TCGA-18-3411	LUSC	TCGA	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation altering degron motif	0.5999
p.L387M	DO26758	LUSC	ICGC	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation altering degron motif	0.5999
p.R310Q	TCGA-19-1787	GBM	TCGA	ARRILQSLE	DEG_APCC_DBOX_1	308:316	Mutation altering degron motif	0.6218
p.R310Q	DO13522	GBM	ICGC	ARRILQSLE	DEG_APCC_DBOX_1	308:316	Mutation altering degron motif	0.6218
p.Q1256E	TCGA-55-8208	LUAD	TCGA	AESST	DEG_SPOP_SBC_1	1244:1248	Mutation rewiring degron network	0.1111
p.Q1256E	TCGA-55-8208	LUAD	TCGA	ATTSS	DEG_SPOP_SBC_1	1261:1265	Mutation rewiring degron network	0.1944
p.Q1256E	DO51192	LUAD	ICGC	AESST	DEG_SPOP_SBC_1	1244:1248	Mutation rewiring degron network	0.1111
p.Q1256E	DO51192	LUAD	ICGC	ATTSS	DEG_SPOP_SBC_1	1261:1265	Mutation rewiring degron network	0.1944
p.S1457C	TCGA-56-7822	LUSC	TCGA	VFSSS	DEG_SPOP_SBC_1	1454:1458	Mutation altering degron motif	0.8652
p.S1457C	DO26638	LUSC	ICGC	VFSSS	DEG_SPOP_SBC_1	1454:1458	Mutation altering degron motif	0.8652
p.T116A	TCGA-60-2719	LUSC	TCGA	PSTTS	DEG_SPOP_SBC_1	113:117	Mutation altering degron motif	0.7139
p.T116A	DO27453	LUSC	ICGC	PSTTS	DEG_SPOP_SBC_1	113:117	Mutation altering degron motif	0.7139
p.T695S	TCGA-61-1998	OV	TCGA	IETPNKS	DEG_SCF_FBW7_1	697:703	Mutation rewiring degron network	0.2778
p.T695S	DO28813	OV	ICGC	IETPNKS	DEG_SCF_FBW7_1	697:703	Mutation rewiring degron network	0.2778
p.V835L	TCGA-78-7220	LUAD	TCGA	PASSS	DEG_SPOP_SBC_1	826:830	Mutation rewiring degron network	0.1944
p.V835L	DO24409	LUAD	ICGC	PASSS	DEG_SPOP_SBC_1	826:830	Mutation rewiring degron network	0.1944
p.L387V	TCGA-85-A50Z	LUSC	TCGA	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation altering degron motif	0.5654
p.L387V	DO45462	LUSC	ICGC	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation altering degron motif	0.5654
p.T713P	TCGA-A5-A0G2	UCEC	TCGA	IETPNKS	DEG_SCF_FBW7_1	697:703	Mutation rewiring degron network	0.0556
p.T713P	DO41235	UCEC	ICGC	IETPNKS	DEG_SCF_FBW7_1	697:703	Mutation rewiring degron network	0.0556
p.A1382V	TCGA-A5-A1OF	UCEC	TCGA	PNSSS	DEG_SPOP_SBC_1	1389:1393	Mutation rewiring degron network	0.1389
p.A1382V	DO42568	UCEC	ICGC	PNSSS	DEG_SPOP_SBC_1	1389:1393	Mutation rewiring degron network	0.1389
p.A1020E	TCGA-AA-3821	COAD	TCGA	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation rewiring degron network	0.3056
p.A1020E	DO9314	COAD	ICGC	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation rewiring degron network	0.3056
p.S1433L	TCGA-AA-A010	COAD	TCGA	ANSST	DEG_SPOP_SBC_1	1419:1423	Mutation rewiring degron network	0.0556
p.S891Y	TCGA-AJ-A3EK	UCEC	TCGA	AASSS	DEG_SPOP_SBC_1	898:902	Mutation blocking phosphorylation signal	0.5833
p.S891Y	DO229038	LICA	ICGC	AASSS	DEG_SPOP_SBC_1	898:902	Mutation blocking phosphorylation signal	0.5833
p.S891Y	DO41584	UCEC	ICGC	AASSS	DEG_SPOP_SBC_1	898:902	Mutation blocking phosphorylation signal	0.5833
p.S764L	TCGA-AN-A046	BRCA	TCGA	ASSSS	DEG_SPOP_SBC_1	772:776	Mutation rewiring degron network	0.1111
p.S764L	TCGA-EE-A2MJ	SKCM	TCGA	ASSSS	DEG_SPOP_SBC_1	772:776	Mutation rewiring degron network	0.1111
p.S764L	DO1285	BRCA	ICGC	ASSSS	DEG_SPOP_SBC_1	772:776	Mutation rewiring degron network	0.1111
p.S764L	DO220885	MELA	ICGC	ASSSS	DEG_SPOP_SBC_1	772:776	Mutation rewiring degron network	0.1111
p.S764L	DO38099	SKCM	ICGC	ASSSS	DEG_SPOP_SBC_1	772:776	Mutation rewiring degron network	0.1111
p.A1167T	TCGA-AP-A059	UCEC	TCGA	AQTST	DEG_SPOP_SBC_1	1175:1179	Mutation rewiring degron network	0.1111
p.A1167T	DO41361	UCEC	ICGC	AQTST	DEG_SPOP_SBC_1	1175:1179	Mutation rewiring degron network	0.1111
p.S386Y	TCGA-AP-A059	UCEC	TCGA	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation altering degron motif	0.712
p.S386Y	DO41361	UCEC	ICGC	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation altering degron motif	0.712
p.F1462L	TCGA-AP-A0LM	UCEC	TCGA	VFSSS	DEG_SPOP_SBC_1	1454:1458	Mutation rewiring degron network	0.2222
p.F1462L	DO1101	BRCA	ICGC	VFSSS	DEG_SPOP_SBC_1	1454:1458	Mutation rewiring degron network	0.2222
p.F1462L	DO43306	UCEC	ICGC	VFSSS	DEG_SPOP_SBC_1	1454:1458	Mutation rewiring degron network	0.2222
p.G302S	TCGA-AP-A0LM	UCEC	TCGA	ARRILQSLE	DEG_APCC_DBOX_1	308:316	Mutation rewiring degron network	0.1667
p.G302S	TCGA-AP-A0LM	UCEC	TCGA	VTSST	DEG_SPOP_SBC_1	303:307	Mutation rewiring degron network	0.3056
p.G302S	DO43306	UCEC	ICGC	ARRILQSLE	DEG_APCC_DBOX_1	308:316	Mutation rewiring degron network	0.1667
p.G302S	DO43306	UCEC	ICGC	VTSST	DEG_SPOP_SBC_1	303:307	Mutation rewiring degron network	0.3056
p.A1122D	TCGA-AR-A1AO	BRCA	TCGA	PVTST	DEG_SPOP_SBC_1	1110:1114	Mutation rewiring degron network	0.1111
p.A1122D	DO4443	BRCA	ICGC	PVTST	DEG_SPOP_SBC_1	1110:1114	Mutation rewiring degron network	0.1111
p.R379Q	TCGA-AX-A05Z	UCEC	TCGA	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation rewiring degron network	0.1667
p.R379Q	TCGA-EO-A22X	UCEC	TCGA	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation rewiring degron network	0.1667
p.R379Q	DO222762	COCA	ICGC	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation rewiring degron network	0.1667
p.R379Q	DO40884	UCEC	ICGC	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation rewiring degron network	0.1667
p.R379Q	DO43907	UCEC	ICGC	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation rewiring degron network	0.1667
p.E819D	TCGA-AX-A1CE	UCEC	TCGA	PASSS	DEG_SPOP_SBC_1	826:830	Mutation rewiring degron network	0.1389
p.E819D	DO42280	UCEC	ICGC	PASSS	DEG_SPOP_SBC_1	826:830	Mutation rewiring degron network	0.1389
p.S1391P	TCGA-AX-A2HC	UCEC	TCGA	PNSSS	DEG_SPOP_SBC_1	1389:1393	Mutation altering degron motif	0.6752
p.S1391P	DO41572	UCEC	ICGC	PNSSS	DEG_SPOP_SBC_1	1389:1393	Mutation altering degron motif	0.6752
p.G1027D	TCGA-B5-A3FA	UCEC	TCGA	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation rewiring degron network	0.1111
p.G1027D	DO52402	UCEC	ICGC	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation rewiring degron network	0.1111
p.I311L	TCGA-B5-A3FC	UCEC	TCGA	ARRILQSLE	DEG_APCC_DBOX_1	308:316	Mutation altering degron motif	0.6063
p.I311L	DO41871	UCEC	ICGC	ARRILQSLE	DEG_APCC_DBOX_1	308:316	Mutation altering degron motif	0.6063
p.S1237N	TCGA-B5-A5OC	UCEC	TCGA	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation altering degron motif	0.7069
p.S1237N	DO52405	UCEC	ICGC	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation altering degron motif	0.7069
p.S1237N	ACH-000647	Esophageal Cancer	CCLE	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation altering degron motif	0.7069
p.S1237N	TE-1	oesophagus	COSMIC	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation altering degron motif	0.7069
p.T1401I	TCGA-BG-A3EW	UCEC	TCGA	PNSSS	DEG_SPOP_SBC_1	1389:1393	Mutation rewiring degron network	0.1111
p.T1401I	DO48172	UCEC	ICGC	PNSSS	DEG_SPOP_SBC_1	1389:1393	Mutation rewiring degron network	0.1111
p.E768Q	TCGA-BH-A0DZ	BRCA	TCGA	ASSSS	DEG_SPOP_SBC_1	772:776	Mutation rewiring degron network	0.2222
p.E768Q	DO2919	BRCA	ICGC	ASSSS	DEG_SPOP_SBC_1	772:776	Mutation rewiring degron network	0.2222
p.F786V	TCGA-BR-6452	STAD	TCGA	ASSSS	DEG_SPOP_SBC_1	772:776	Mutation rewiring degron network	0.0556
p.F786V	DO38404	STAD	ICGC	ASSSS	DEG_SPOP_SBC_1	772:776	Mutation rewiring degron network	0.0556
p.T771S	TCGA-BR-6452	STAD	TCGA	ASSSS	DEG_SPOP_SBC_1	772:776	Mutation rewiring degron network	0.3056
p.T771S	DO38404	STAD	ICGC	ASSSS	DEG_SPOP_SBC_1	772:776	Mutation rewiring degron network	0.3056
p.A1169V	TCGA-CG-5721	STAD	TCGA	AQTST	DEG_SPOP_SBC_1	1175:1179	Mutation rewiring degron network	0.1667
p.A1169V	DO233261	GACA	ICGC	AQTST	DEG_SPOP_SBC_1	1175:1179	Mutation rewiring degron network	0.1667
p.A1169V	DO38192	STAD	ICGC	AQTST	DEG_SPOP_SBC_1	1175:1179	Mutation rewiring degron network	0.1667
p.S1236G	TCGA-CJ-6028	KIRC	TCGA	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation altering degron motif	0.6993
p.S1236G	DO16803	KIRC	ICGC	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation altering degron motif	0.6993
p.P492S	TCGA-CV-5439	HNSC	TCGA	PITSS	DEG_SPOP_SBC_1	478:482	Mutation rewiring degron network	0.0556
p.P492S	DO14200	HNSC	ICGC	PITSS	DEG_SPOP_SBC_1	478:482	Mutation rewiring degron network	0.0556
p.S380I	TCGA-D1-A103	UCEC	TCGA	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation blocking phosphorylation signal	0.6389
p.S380I	DO42312	UCEC	ICGC	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation blocking phosphorylation signal	0.6389
p.E1104K	TCGA-D8-A1JA	BRCA	TCGA	PVTST	DEG_SPOP_SBC_1	1110:1114	Mutation rewiring degron network	0.1667
p.E1104K	DO2819	BRCA	ICGC	PVTST	DEG_SPOP_SBC_1	1110:1114	Mutation rewiring degron network	0.1667
p.F1395L	TCGA-D8-A27G	BRCA	TCGA	PNSSS	DEG_SPOP_SBC_1	1389:1393	Mutation rewiring degron network	0.2778
p.F1395L	DO5465	BRCA	ICGC	PNSSS	DEG_SPOP_SBC_1	1389:1393	Mutation rewiring degron network	0.2778
p.Q295R	TCGA-DF-A2KU	UCEC	TCGA	VTSST	DEG_SPOP_SBC_1	303:307	Mutation rewiring degron network	0.1111
p.Q295R	DO223286	UCEC	ICGC	VTSST	DEG_SPOP_SBC_1	303:307	Mutation rewiring degron network	0.1111
p.A119T	TCGA-DK-A2I4	BLCA	TCGA	PSTTS	DEG_SPOP_SBC_1	113:117	Mutation rewiring degron network	0.2778
p.A119T	DO465	BLCA	ICGC	PSTTS	DEG_SPOP_SBC_1	113:117	Mutation rewiring degron network	0.2778
p.E1105D	TCGA-DK-A6AW	BLCA	TCGA	PVTST	DEG_SPOP_SBC_1	1110:1114	Mutation rewiring degron network	0.1944
p.E1105D	DO48566	BLCA	ICGC	PVTST	DEG_SPOP_SBC_1	1110:1114	Mutation rewiring degron network	0.1944
p.E111K	TCGA-DU-6392	LGG	TCGA	PSTTS	DEG_SPOP_SBC_1	113:117	Mutation rewiring degron network	0.2778
p.E111K	DO22237	LGG	ICGC	PSTTS	DEG_SPOP_SBC_1	113:117	Mutation rewiring degron network	0.2778
p.K1010Q	TCGA-E6-A1LX	UCEC	TCGA	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation blocking ubiquitination signal	0.6389
p.K1010Q	DO41020	UCEC	ICGC	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation blocking ubiquitination signal	0.6389
p.A155T	TCGA-E6-A1M0	UCEC	TCGA	PSTSS	DEG_SPOP_SBC_1	150:154	Mutation rewiring degron network	0.3056
p.A155T	DO43682	UCEC	ICGC	PSTSS	DEG_SPOP_SBC_1	150:154	Mutation rewiring degron network	0.3056
p.P838S	TCGA-EE-A20F	SKCM	TCGA	PASSS	DEG_SPOP_SBC_1	826:830	Mutation rewiring degron network	0.1111
p.P838S	DO37961	SKCM	ICGC	PASSS	DEG_SPOP_SBC_1	826:830	Mutation rewiring degron network	0.1111
p.R394M	TCGA-EE-A2GM	SKCM	TCGA	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation rewiring degron network	0.2778
p.R394M	DO37555	SKCM	ICGC	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation rewiring degron network	0.2778
p.S161L	TCGA-EO-A22U	UCEC	TCGA	PSTSS	DEG_SPOP_SBC_1	150:154	Mutation rewiring degron network	0.1389
p.S161L	DO43755	UCEC	ICGC	PSTSS	DEG_SPOP_SBC_1	150:154	Mutation rewiring degron network	0.1389
p.G1413E	TCGA-EO-A22X	UCEC	TCGA	ANSST	DEG_SPOP_SBC_1	1419:1423	Mutation rewiring degron network	0.1667
p.G1413E	DO43907	UCEC	ICGC	ANSST	DEG_SPOP_SBC_1	1419:1423	Mutation rewiring degron network	0.1667
p.S491F	TCGA-ER-A19P	SKCM	TCGA	PITSS	DEG_SPOP_SBC_1	478:482	Mutation rewiring degron network	0.0833
p.S491F	DO47623	SKCM	ICGC	PITSS	DEG_SPOP_SBC_1	478:482	Mutation rewiring degron network	0.0833
p.S1299A	TCGA-F4-6703	COAD	TCGA	ATTTS	DEG_SPOP_SBC_1	1293:1297	Mutation rewiring degron network	0.2778
p.S1299A	DO9908	COAD	ICGC	ATTTS	DEG_SPOP_SBC_1	1293:1297	Mutation rewiring degron network	0.2778
p.S164F	TCGA-F5-6814	READ	TCGA	PSTSS	DEG_SPOP_SBC_1	150:154	Mutation rewiring degron network	0.0556
p.S164F	DO36556	READ	ICGC	PSTSS	DEG_SPOP_SBC_1	150:154	Mutation rewiring degron network	0.0556
p.P914L	TCGA-FW-A3R5	SKCM	TCGA	VSSSS	DEG_SPOP_SBC_1	907:911	Mutation rewiring degron network	0.25
p.P914L	DO37406	SKCM	ICGC	VSSSS	DEG_SPOP_SBC_1	907:911	Mutation rewiring degron network	0.25
p.E316Q	TCGA-JW-A5VL	CESC	TCGA	ARRILQSLE	DEG_APCC_DBOX_1	308:316	Mutation altering degron motif	0.5633
p.E316Q	DO49976	CESC	ICGC	ARRILQSLE	DEG_APCC_DBOX_1	308:316	Mutation altering degron motif	0.5633
p.S1412L	TCGA-KQ-A41P	BLCA	TCGA	ANSST	DEG_SPOP_SBC_1	1419:1423	Mutation rewiring degron network	0.1389
p.S1412L	DO223590	BLCA	ICGC	ANSST	DEG_SPOP_SBC_1	1419:1423	Mutation rewiring degron network	0.1389
p.S1299C	TCGA-LP-A5U2	CESC	TCGA	ATTTS	DEG_SPOP_SBC_1	1293:1297	Mutation rewiring degron network	0.2778
p.S1299C	DO51610	CESC	ICGC	ATTTS	DEG_SPOP_SBC_1	1293:1297	Mutation rewiring degron network	0.2778
p.K474N	TCGA-NK-A5D1	LUSC	TCGA	PITSS	DEG_SPOP_SBC_1	478:482	Mutation substituting flanking lysine	0.3333
p.K474N	DO219213	LUSC	ICGC	PITSS	DEG_SPOP_SBC_1	478:482	Mutation substituting flanking lysine	0.3333
p.N701S	TCGA-RP-A695	SKCM	TCGA	IETPNKS	DEG_SCF_FBW7_1	697:703	Mutation altering degron motif	0.5958
p.N701S	DO51270	SKCM	ICGC	IETPNKS	DEG_SCF_FBW7_1	697:703	Mutation altering degron motif	0.5958
p.A1419E	TCGA-UF-A7JO	HNSC	TCGA	ANSST	DEG_SPOP_SBC_1	1419:1423	Mutation altering degron motif	0.7701
p.A1419E	DO219088	HNSC	ICGC	ANSST	DEG_SPOP_SBC_1	1419:1423	Mutation altering degron motif	0.7701
p.L475R	DO44097	BLCA	ICGC	PITSS	DEG_SPOP_SBC_1	478:482	Mutation rewiring degron network	0.25
p.A1239V	DO225042	BRCA	ICGC	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation rewiring degron network	0.3056
p.A1239V	DO225042	BRCA	ICGC	AESST	DEG_SPOP_SBC_1	1244:1248	Mutation rewiring degron network	0.1944
p.C816W	DO224741	BRCA	ICGC	PASSS	DEG_SPOP_SBC_1	826:830	Mutation rewiring degron network	0.0556
p.C816W	DO52542	BRCA	ICGC	PASSS	DEG_SPOP_SBC_1	826:830	Mutation rewiring degron network	0.0556
p.A827T	DO229013	COCA	ICGC	PASSS	DEG_SPOP_SBC_1	826:830	Mutation altering degron motif	0.6028
p.A827T	DO229016	COCA	ICGC	PASSS	DEG_SPOP_SBC_1	826:830	Mutation altering degron motif	0.6028
p.A827T	DO229003	COCA	ICGC	PASSS	DEG_SPOP_SBC_1	826:830	Mutation altering degron motif	0.6028
p.A827T	DO229005	COCA	ICGC	PASSS	DEG_SPOP_SBC_1	826:830	Mutation altering degron motif	0.6028
p.N402K	DO229016	COCA	ICGC	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation rewiring degron network	0.0556
p.N402K	DO230659	LAML	ICGC	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation rewiring degron network	0.0556
p.N402K	DO228947	LICA	ICGC	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation rewiring degron network	0.0556
p.N402K	DO52365	LUSC	ICGC	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation rewiring degron network	0.0556
p.S1287F	DO50354	ESAD	ICGC	ATTTS	DEG_SPOP_SBC_1	1293:1297	Mutation rewiring degron network	0.1667
p.P1272Q	DO233693	GACA	ICGC	ATTSS	DEG_SPOP_SBC_1	1261:1265	Mutation rewiring degron network	0.1389
p.P489S	DO233746	GACA	ICGC	PITSS	DEG_SPOP_SBC_1	478:482	Mutation rewiring degron network	0.1389
p.A1394T	DO233804	GACA	ICGC	PNSSS	DEG_SPOP_SBC_1	1389:1393	Mutation rewiring degron network	0.3056
p.T118N	DO228900	LICA	ICGC	PSTTS	DEG_SPOP_SBC_1	113:117	Mutation rewiring degron network	0.3056
p.T118N	DO228976	LICA	ICGC	PSTTS	DEG_SPOP_SBC_1	113:117	Mutation rewiring degron network	0.3056
p.A1181D	DO228974	LICA	ICGC	AQTST	DEG_SPOP_SBC_1	1175:1179	Mutation rewiring degron network	0.2778
p.A1181D	DO229038	LICA	ICGC	AQTST	DEG_SPOP_SBC_1	1175:1179	Mutation rewiring degron network	0.2778
p.P123Q	DO228976	LICA	ICGC	PSTTS	DEG_SPOP_SBC_1	113:117	Mutation rewiring degron network	0.1667
p.P385Q	DO228971	LICA	ICGC	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation altering degron motif	0.7035
p.T919K	DO229028	LICA	ICGC	VSSSS	DEG_SPOP_SBC_1	907:911	Mutation rewiring degron network	0.1111
p.P1411Q	DO229025	LICA	ICGC	ANSST	DEG_SPOP_SBC_1	1419:1423	Mutation rewiring degron network	0.1111
p.Q1165K	DO229032	LICA	ICGC	AQTST	DEG_SPOP_SBC_1	1175:1179	Mutation rewiring degron network	0.0556
p.A293D	DO229032	LICA	ICGC	VTSST	DEG_SPOP_SBC_1	303:307	Mutation rewiring degron network	0.0556
p.S300Y	DO229036	LICA	ICGC	ARRILQSLE	DEG_APCC_DBOX_1	308:316	Mutation rewiring degron network	0.1111
p.S300Y	DO229036	LICA	ICGC	VTSST	DEG_SPOP_SBC_1	303:307	Mutation rewiring degron network	0.25
p.T307K	DO229036	LICA	ICGC	VTSST	DEG_SPOP_SBC_1	303:307	Mutation altering degron motif	0.7306
p.A767D	DO229041	LICA	ICGC	ASSSS	DEG_SPOP_SBC_1	772:776	Mutation rewiring degron network	0.1944
p.Q295K	DO229045	LICA	ICGC	VTSST	DEG_SPOP_SBC_1	303:307	Mutation rewiring degron network	0.1111
p.P105T	DO229045	LICA	ICGC	PSTTS	DEG_SPOP_SBC_1	113:117	Mutation rewiring degron network	0.1111
p.P826T	DO229056	LICA	ICGC	PASSS	DEG_SPOP_SBC_1	826:830	Mutation altering degron motif	0.7031
p.P478T	DO229009	LICA	ICGC	PITSS	DEG_SPOP_SBC_1	478:482	Mutation altering degron motif	0.7031
p.F903L	DO229008	LICA	ICGC	AASSS	DEG_SPOP_SBC_1	898:902	Mutation rewiring degron network	0.3056
p.F903L	DO229008	LICA	ICGC	VSSSS	DEG_SPOP_SBC_1	907:911	Mutation rewiring degron network	0.2222
p.G468A	DO45265	LIRI	ICGC	PITSS	DEG_SPOP_SBC_1	478:482	Mutation rewiring degron network	0.0556
p.S160N	DO229177	LMS	ICGC	PSTSS	DEG_SPOP_SBC_1	150:154	Mutation rewiring degron network	0.1667
p.P486S	DO220856	MELA	ICGC	PITSS	DEG_SPOP_SBC_1	478:482	Mutation rewiring degron network	0.2222
p.F903V	DO46546	OV	ICGC	AASSS	DEG_SPOP_SBC_1	898:902	Mutation rewiring degron network	0.3056
p.F903V	DO46546	OV	ICGC	VSSSS	DEG_SPOP_SBC_1	907:911	Mutation rewiring degron network	0.2222
p.F1171I	DO221547	PACA	ICGC	AQTST	DEG_SPOP_SBC_1	1175:1179	Mutation rewiring degron network	0.2222
p.A481T	DO48915	PBCA	ICGC	PITSS	DEG_SPOP_SBC_1	478:482	Mutation altering degron motif	0.7139
p.S901L	DO51047	PRAD	ICGC	AASSS	DEG_SPOP_SBC_1	898:902	Mutation altering degron motif	0.8778
p.A1172V	DO229117	PRAD	ICGC	AQTST	DEG_SPOP_SBC_1	1175:1179	Mutation rewiring degron network	0.25
p.A1172S	DO229117	PRAD	ICGC	AQTST	DEG_SPOP_SBC_1	1175:1179	Mutation rewiring degron network	0.25
p.S1265C	DO47140	RECA	ICGC	ATTSS	DEG_SPOP_SBC_1	1261:1265	Mutation altering degron motif	0.7541
p.V1305L	DO229208	THCA	ICGC	ATTTS	DEG_SPOP_SBC_1	1293:1297	Mutation rewiring degron network	0.1111
p.S154L	DO230449	UTCA	ICGC	PSTSS	DEG_SPOP_SBC_1	150:154	Mutation altering degron motif	0.7667
p.K317R	SIDM02063	Colorectal Carcinoma	GDSC	ARRILQSLE	DEG_APCC_DBOX_1	308:316	Mutation blocking ubiquitination signal	0.75
p.K317R	SIDM02063	Colorectal Carcinoma	GDSC	VTSST	DEG_SPOP_SBC_1	303:307	Mutation blocking ubiquitination signal	0.5
p.G162E	SIDM01141	Ovarian Carcinoma	GDSC	PSTSS	DEG_SPOP_SBC_1	150:154	Mutation rewiring degron network	0.1111
p.G162E	ACH-000291	Ovarian Cancer	CCLE	PSTSS	DEG_SPOP_SBC_1	150:154	Mutation rewiring degron network	0.1111
p.G162E	OV-90	ovary	COSMIC	PSTSS	DEG_SPOP_SBC_1	150:154	Mutation rewiring degron network	0.1111
p.S1245N	SIDM00773	Non-Cancerous	GDSC	AESST	DEG_SPOP_SBC_1	1244:1248	Mutation altering degron motif	0.7069
p.S1245N	SIDM01126	Small Cell Lung Carcinoma	GDSC	AESST	DEG_SPOP_SBC_1	1244:1248	Mutation altering degron motif	0.7069
p.S1245N	SIDM00210	Ovarian Carcinoma	GDSC	AESST	DEG_SPOP_SBC_1	1244:1248	Mutation altering degron motif	0.7069
p.S1245N	SIDM00793	Burkitt's Lymphoma	GDSC	AESST	DEG_SPOP_SBC_1	1244:1248	Mutation altering degron motif	0.7069
p.S1245N	SIDM00774	Breast Carcinoma	GDSC	AESST	DEG_SPOP_SBC_1	1244:1248	Mutation altering degron motif	0.7069
p.S1245N	SIDM00720	Mesothelioma	GDSC	AESST	DEG_SPOP_SBC_1	1244:1248	Mutation altering degron motif	0.7069
p.S1245N	SIDM01318	Hepatocellular Carcinoma	GDSC	AESST	DEG_SPOP_SBC_1	1244:1248	Mutation altering degron motif	0.7069
p.T1233A	SIDM00773	Non-Cancerous	GDSC	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation rewiring degron network	0.3056
p.T1233A	SIDM00845	Burkitt's Lymphoma	GDSC	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation rewiring degron network	0.3056
p.T1233A	SIDM01126	Small Cell Lung Carcinoma	GDSC	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation rewiring degron network	0.3056
p.T1233A	SIDM00210	Ovarian Carcinoma	GDSC	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation rewiring degron network	0.3056
p.T1233A	SIDM00793	Burkitt's Lymphoma	GDSC	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation rewiring degron network	0.3056
p.T1233A	SIDM00774	Breast Carcinoma	GDSC	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation rewiring degron network	0.3056
p.T1233A	SIDM00720	Mesothelioma	GDSC	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation rewiring degron network	0.3056
p.T1233A	SIDM01318	Hepatocellular Carcinoma	GDSC	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation rewiring degron network	0.3056
p.N1226S	SIDM00845	Burkitt's Lymphoma	GDSC	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation rewiring degron network	0.1111
p.T1419A	SIDM00967	Ovarian Carcinoma	GDSC	ANSST	DEG_SPOP_SBC_1	1419:1423	Mutation altering degron motif	0.7139
p.T1419A	SIDM00971	Breast Carcinoma	GDSC	ANSST	DEG_SPOP_SBC_1	1419:1423	Mutation altering degron motif	0.7139
p.T1419A	SIDM00844	Burkitt's Lymphoma	GDSC	ANSST	DEG_SPOP_SBC_1	1419:1423	Mutation altering degron motif	0.7139
p.T1419A	SIDM00032	Bladder Carcinoma	GDSC	ANSST	DEG_SPOP_SBC_1	1419:1423	Mutation altering degron motif	0.7139
p.T1419A	SIDM01147	Gastric Carcinoma	GDSC	ANSST	DEG_SPOP_SBC_1	1419:1423	Mutation altering degron motif	0.7139
p.G1466C	SIDM01219	Non-Small Cell Lung Carcinoma	GDSC	VFSSS	DEG_SPOP_SBC_1	1454:1458	Mutation substituting flanking lysine	0.2222
p.G1466C	SIDM00607	Glioblastoma	GDSC	VFSSS	DEG_SPOP_SBC_1	1454:1458	Mutation substituting flanking lysine	0.2222
p.G1466C	SIDM00251	Gastric Carcinoma	GDSC	VFSSS	DEG_SPOP_SBC_1	1454:1458	Mutation substituting flanking lysine	0.2222
p.G1466C	SIDM00564	Ovarian Carcinoma	GDSC	VFSSS	DEG_SPOP_SBC_1	1454:1458	Mutation substituting flanking lysine	0.2222
p.G1466C	SIDM01575	Plasma Cell Myeloma	GDSC	VFSSS	DEG_SPOP_SBC_1	1454:1458	Mutation substituting flanking lysine	0.2222
p.G1466C	SIDM00162	Biliary Tract Carcinoma	GDSC	VFSSS	DEG_SPOP_SBC_1	1454:1458	Mutation substituting flanking lysine	0.2222
p.G1466C	TGBC11TKB	stomach	COSMIC	VFSSS	DEG_SPOP_SBC_1	1454:1458	Mutation substituting flanking lysine	0.2222
p.G1466C	LU-99A	lung	COSMIC	VFSSS	DEG_SPOP_SBC_1	1454:1458	Mutation substituting flanking lysine	0.2222
p.G1466C	KNS-42	central nervous system	COSMIC	VFSSS	DEG_SPOP_SBC_1	1454:1458	Mutation substituting flanking lysine	0.2222
p.G1466C	OVISE	ovary	COSMIC	VFSSS	DEG_SPOP_SBC_1	1454:1458	Mutation substituting flanking lysine	0.2222
p.A323V	SIDM00789	Colorectal Carcinoma	GDSC	ARRILQSLE	DEG_APCC_DBOX_1	308:316	Mutation rewiring degron network	0.1389
p.A323V	HCT-15	large intestine	COSMIC	ARRILQSLE	DEG_APCC_DBOX_1	308:316	Mutation rewiring degron network	0.1389
p.S1268N	SIDM00369	Esophageal Squamous Cell Carcinoma	GDSC	ATTSS	DEG_SPOP_SBC_1	1261:1265	Mutation rewiring degron network	0.25
p.S1268N	TE-1	oesophagus	COSMIC	ATTSS	DEG_SPOP_SBC_1	1261:1265	Mutation rewiring degron network	0.25
p.V1258E	SIDM00654	Small Cell Lung Carcinoma	GDSC	AESST	DEG_SPOP_SBC_1	1244:1248	Mutation rewiring degron network	0.0556
p.V1258E	SIDM00654	Small Cell Lung Carcinoma	GDSC	ATTSS	DEG_SPOP_SBC_1	1261:1265	Mutation rewiring degron network	0.25
p.V1258E	NCI-H1048	lung	COSMIC	AESST	DEG_SPOP_SBC_1	1244:1248	Mutation rewiring degron network	0.0556
p.V1258E	NCI-H1048	lung	COSMIC	ATTSS	DEG_SPOP_SBC_1	1261:1265	Mutation rewiring degron network	0.25
p.G911D	SIDM00193	Colorectal Carcinoma	GDSC	VSSSS	DEG_SPOP_SBC_1	907:911	Mutation altering degron motif	0.7198
p.G911D	SNU-81	large intestine	COSMIC	VSSSS	DEG_SPOP_SBC_1	907:911	Mutation altering degron motif	0.7198
p.K317N	SIDM00193	Colorectal Carcinoma	GDSC	ARRILQSLE	DEG_APCC_DBOX_1	308:316	Mutation blocking ubiquitination signal	0.75
p.K317N	SIDM00193	Colorectal Carcinoma	GDSC	VTSST	DEG_SPOP_SBC_1	303:307	Mutation blocking ubiquitination signal	0.5
p.K317N	ACH-000991	Colon/Colorectal Cancer	CCLE	ARRILQSLE	DEG_APCC_DBOX_1	308:316	Mutation blocking ubiquitination signal	0.75
p.K317N	ACH-000991	Colon/Colorectal Cancer	CCLE	VTSST	DEG_SPOP_SBC_1	303:307	Mutation blocking ubiquitination signal	0.5
p.K317N	SNU-81	large intestine	COSMIC	ARRILQSLE	DEG_APCC_DBOX_1	308:316	Mutation blocking ubiquitination signal	0.75
p.K317N	SNU-81	large intestine	COSMIC	VTSST	DEG_SPOP_SBC_1	303:307	Mutation blocking ubiquitination signal	0.5
p.V785M	SIDM01144	Gastric Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	772:776	Mutation rewiring degron network	0.0833
p.V785M	NCI-SNU-5	stomach	COSMIC	ASSSS	DEG_SPOP_SBC_1	772:776	Mutation rewiring degron network	0.0833
p.L1291P	SIDM00716	Squamous Cell Lung Carcinoma	GDSC	ATTTS	DEG_SPOP_SBC_1	1293:1297	Mutation rewiring degron network	0.2778
p.L1291P	NCI-H2170	lung	COSMIC	ATTTS	DEG_SPOP_SBC_1	1293:1297	Mutation rewiring degron network	0.2778
p.S161W	SIDM00350	Head and Neck Carcinoma	GDSC	PSTSS	DEG_SPOP_SBC_1	150:154	Mutation rewiring degron network	0.1389
p.S161W	ACH-001641	Head and Neck Cancer	CCLE	PSTSS	DEG_SPOP_SBC_1	150:154	Mutation rewiring degron network	0.1389
p.S161W	SAT	upper aerodigestive tract	COSMIC	PSTSS	DEG_SPOP_SBC_1	150:154	Mutation rewiring degron network	0.1389
p.S1462L	SIDM00895	B-Cell Non-Hodgkin's Lymphoma	GDSC	VFSSS	DEG_SPOP_SBC_1	1454:1458	Mutation rewiring degron network	0.2222
p.S1462L	BC-3	haematopoietic and lymphoid tissue	COSMIC	VFSSS	DEG_SPOP_SBC_1	1454:1458	Mutation rewiring degron network	0.2222
p.A839T	SIDM00650	Small Cell Lung Carcinoma	GDSC	PASSS	DEG_SPOP_SBC_1	826:830	Mutation rewiring degron network	0.0833
p.A839T	NCI-H128	lung	COSMIC	PASSS	DEG_SPOP_SBC_1	826:830	Mutation rewiring degron network	0.0833
p.F821L	SIDM00708	Non-Small Cell Lung Carcinoma	GDSC	PASSS	DEG_SPOP_SBC_1	826:830	Mutation rewiring degron network	0.1944
p.F821L	NCI-H2087	lung	COSMIC	PASSS	DEG_SPOP_SBC_1	826:830	Mutation rewiring degron network	0.1944
p.S1025C	SIDM00265	Ewing's Sarcoma	GDSC	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation rewiring degron network	0.1667
p.S1025C	ES3	bone	COSMIC	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation rewiring degron network	0.1667
p.S1374F	SIDM00278	Esophageal Squamous Cell Carcinoma	GDSC	VSSSS	DEG_SPOP_SBC_1	1365:1369	Mutation rewiring degron network	0.1944
p.S1374F	EC-GI-10	oesophagus	COSMIC	VSSSS	DEG_SPOP_SBC_1	1365:1369	Mutation rewiring degron network	0.1944
p.M318I	SIDM00651	Non-Small Cell Lung Carcinoma	GDSC	ARRILQSLE	DEG_APCC_DBOX_1	308:316	Mutation rewiring degron network	0.2778
p.M318I	ACH-000980	Lung Cancer	CCLE	ARRILQSLE	DEG_APCC_DBOX_1	308:316	Mutation rewiring degron network	0.2778
p.M318I	NCI-H1155	lung	COSMIC	ARRILQSLE	DEG_APCC_DBOX_1	308:316	Mutation rewiring degron network	0.2778
p.A711T	SIDM00217	Colorectal Carcinoma	GDSC	IETPNKS	DEG_SCF_FBW7_1	697:703	Mutation blocking phosphorylation signal	0.5556
p.A711T	SNU-1040	large intestine	COSMIC	IETPNKS	DEG_SCF_FBW7_1	697:703	Mutation blocking phosphorylation signal	0.5556
p.A106T	SIDM00217	Colorectal Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	113:117	Mutation rewiring degron network	0.1389
p.A106T	ACH-000999	Colon/Colorectal Cancer	CCLE	PSTTS	DEG_SPOP_SBC_1	113:117	Mutation rewiring degron network	0.1389
p.A106T	SNU-1040	large intestine	COSMIC	PSTTS	DEG_SPOP_SBC_1	113:117	Mutation rewiring degron network	0.1389
p.K703N	SIDM00118	Colorectal Carcinoma	GDSC	IETPNKS	DEG_SCF_FBW7_1	697:703	Mutation altering degron motif	0.6918
p.K703N	HCC2998	large intestine	COSMIC	IETPNKS	DEG_SCF_FBW7_1	697:703	Mutation altering degron motif	0.6918
p.T1392I	SIDM00867	Glioblastoma	GDSC	PNSSS	DEG_SPOP_SBC_1	1389:1393	Mutation altering degron motif	0.7078
p.T1392I	DBTRG-05MG	central nervous system	COSMIC	PNSSS	DEG_SPOP_SBC_1	1389:1393	Mutation altering degron motif	0.7078
p.I1375L	SIDM00225	Melanoma	GDSC	VSSSS	DEG_SPOP_SBC_1	1365:1369	Mutation rewiring degron network	0.1667
p.I1375L	IST-MEL1	skin	COSMIC	VSSSS	DEG_SPOP_SBC_1	1365:1369	Mutation rewiring degron network	0.1667
p.F1113L	SIDM01608	Endometrial Carcinoma	GDSC	PVTST	DEG_SPOP_SBC_1	1110:1114	Mutation altering degron motif	0.6981
p.V1118M	SIDM01612	Endometrial Carcinoma	GDSC	PVTST	DEG_SPOP_SBC_1	1110:1114	Mutation rewiring degron network	0.2222
p.V1118M	SIDM01450	Gastric Carcinoma	GDSC	PVTST	DEG_SPOP_SBC_1	1110:1114	Mutation rewiring degron network	0.2222
p.P1356L	SIDM01781	Gastric Carcinoma	GDSC	VSSSS	DEG_SPOP_SBC_1	1365:1369	Mutation rewiring degron network	0.0833
p.S1423T	SIDM01689	B-Lymphoblastic Leukemia	GDSC	ANSST	DEG_SPOP_SBC_1	1419:1423	Mutation altering degron motif	0.7116
p.I375V	SIDM00173	Head and Neck Carcinoma	GDSC	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation rewiring degron network	0.0556
p.I375V	ACH-000618	Head and Neck Cancer	CCLE	PSLTPSGE	DEG_SCF_FBW7_2	385:392	Mutation rewiring degron network	0.0556
p.A1270S	SIDM01574	Plasma Cell Myeloma	GDSC	ATTSS	DEG_SPOP_SBC_1	1261:1265	Mutation rewiring degron network	0.1944
p.C902Y	SIDM01756	Chronic Myelogenous Leukemia	GDSC	AASSS	DEG_SPOP_SBC_1	898:902	Mutation altering degron motif	0.7087
p.K913N	SIDM01619	Endometrial Carcinoma	GDSC	VSSSS	DEG_SPOP_SBC_1	907:911	Mutation rewiring degron network	0.2778
p.L1260P	ACH-000481	Lung Cancer	CCLE	ATTSS	DEG_SPOP_SBC_1	1261:1265	Mutation rewiring degron network	0.3056
p.L1260P	NCI-H2170	lung	COSMIC	ATTSS	DEG_SPOP_SBC_1	1261:1265	Mutation rewiring degron network	0.3056
p.S703R	ACH-000507	Gastric Cancer	CCLE	IETPNKS	DEG_SCF_FBW7_1	697:703	Mutation altering degron motif	0.7427
p.A1239S	ACH-000588	Myeloma	CCLE	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation rewiring degron network	0.3056
p.A1239S	ACH-000588	Myeloma	CCLE	AESST	DEG_SPOP_SBC_1	1244:1248	Mutation rewiring degron network	0.1944
p.S1019F	ACH-000672	Lung Cancer	CCLE	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation altering degron motif	0.7982
p.S1019F	IA-LM	lung	COSMIC	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation altering degron motif	0.7982
p.E1012Q	ACH-000706	Lung Cancer	CCLE	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation rewiring degron network	0.25
p.E1012Q	EKVX	lung	COSMIC	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation rewiring degron network	0.25
p.V762L	ACH-000746	Gastric Cancer	CCLE	ASSSS	DEG_SPOP_SBC_1	772:776	Mutation rewiring degron network	0.0556
p.T1361I	ACH-000863	Brain Cancer	CCLE	VSSSS	DEG_SPOP_SBC_1	1365:1369	Mutation rewiring degron network	0.2222
p.T1361I	DBTRG-05MG	central nervous system	COSMIC	VSSSS	DEG_SPOP_SBC_1	1365:1369	Mutation rewiring degron network	0.2222
p.V1227E	ACH-000866	Lung Cancer	CCLE	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation rewiring degron network	0.1389
p.V1227E	NCI-H1048	lung	COSMIC	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation rewiring degron network	0.1389
p.S828L	ACH-000896	Bladder Cancer	CCLE	PASSS	DEG_SPOP_SBC_1	826:830	Mutation altering degron motif	0.7667
p.G712R	ACH-000931	Skin Cancer	CCLE	IETPNKS	DEG_SCF_FBW7_1	697:703	Mutation rewiring degron network	0.0833
p.G712R	ACH-001024	Skin Cancer	CCLE	IETPNKS	DEG_SCF_FBW7_1	697:703	Mutation rewiring degron network	0.0833
p.G712R	CHL-1	skin	COSMIC	IETPNKS	DEG_SCF_FBW7_1	697:703	Mutation rewiring degron network	0.0833
p.V1454M	ACH-000980	Lung Cancer	CCLE	VFSSS	DEG_SPOP_SBC_1	1454:1458	Mutation altering degron motif	0.7208
p.V1454M	NCI-H1155	lung	COSMIC	VFSSS	DEG_SPOP_SBC_1	1454:1458	Mutation altering degron motif	0.7208
p.G1413R	ACH-000985	Colon/Colorectal Cancer	CCLE	ANSST	DEG_SPOP_SBC_1	1419:1423	Mutation rewiring degron network	0.1667
p.S1023G	ACH-000990	Endometrial/Uterine Cancer	CCLE	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation rewiring degron network	0.2222
p.G1184C	ACH-000997	Colon/Colorectal Cancer	CCLE	AQTST	DEG_SPOP_SBC_1	1175:1179	Mutation rewiring degron network	0.1944
p.G1184C	ACH-001061	Colon/Colorectal Cancer	CCLE	AQTST	DEG_SPOP_SBC_1	1175:1179	Mutation rewiring degron network	0.1944
p.G1184C	ACH-001091	Colon/Colorectal Cancer	CCLE	AQTST	DEG_SPOP_SBC_1	1175:1179	Mutation rewiring degron network	0.1944
p.G1184C	HCT-15	large intestine	COSMIC	AQTST	DEG_SPOP_SBC_1	1175:1179	Mutation rewiring degron network	0.1944
p.A1293V	ACH-001518	Endometrial/Uterine Cancer	CCLE	ATTTS	DEG_SPOP_SBC_1	1293:1297	Mutation altering degron motif	0.5825
p.K474E	ACH-001610	Brain Cancer	CCLE	PITSS	DEG_SPOP_SBC_1	478:482	Mutation substituting flanking lysine	0.3333
p.S1431L	ACH-002215	Lymphoma	CCLE	ANSST	DEG_SPOP_SBC_1	1419:1423	Mutation rewiring degron network	0.1111
p.S1431L	BC-3	haematopoietic and lymphoid tissue	COSMIC	ANSST	DEG_SPOP_SBC_1	1419:1423	Mutation rewiring degron network	0.1111
p.S1301F	EC-GI-10	oesophagus	COSMIC	ATTTS	DEG_SPOP_SBC_1	1293:1297	Mutation rewiring degron network	0.2222
p.S1026P	NCI-H1299	lung	COSMIC	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation rewiring degron network	0.1389
p.I901V	CP67-MEL	skin	COSMIC	AASSS	DEG_SPOP_SBC_1	898:902	Mutation altering degron motif	0.7076
p.P485L	NCI-H1573	lung	COSMIC	PITSS	DEG_SPOP_SBC_1	478:482	Mutation rewiring degron network	0.25
p.C773Y	RPMI-2650	upper aerodigestive tract	COSMIC	ASSSS	DEG_SPOP_SBC_1	772:776	Mutation altering degron motif	0.7087
p.G838D	SNU-81	large intestine	COSMIC	PASSS	DEG_SPOP_SBC_1	826:830	Mutation rewiring degron network	0.1111
p.V712M	NCI-SNU-5	stomach	COSMIC	IETPNKS	DEG_SCF_FBW7_1	697:703	Mutation rewiring degron network	0.0833
p.I1302L	IST-MEL1	skin	COSMIC	ATTTS	DEG_SPOP_SBC_1	1293:1297	Mutation rewiring degron network	0.1944
p.T1242I	SISO	cervix	COSMIC	PVSSS	DEG_SPOP_SBC_1	1234:1238	Mutation rewiring degron network	0.2222
p.T1242I	SISO	cervix	COSMIC	AESST	DEG_SPOP_SBC_1	1244:1248	Mutation rewiring degron network	0.2778
p.S481N	MHH-ES-1	bone	COSMIC	PITSS	DEG_SPOP_SBC_1	478:482	Mutation altering degron motif	0.7069
p.G1393C	KNS-42	central nervous system	COSMIC	PNSSS	DEG_SPOP_SBC_1	1389:1393	Mutation altering degron motif	0.76
p.G1393C	TGBC11TKB	stomach	COSMIC	PNSSS	DEG_SPOP_SBC_1	1389:1393	Mutation altering degron motif	0.76
p.G1393C	OVISE	ovary	COSMIC	PNSSS	DEG_SPOP_SBC_1	1389:1393	Mutation altering degron motif	0.76
p.G1393C	LU-99A	lung	COSMIC	PNSSS	DEG_SPOP_SBC_1	1389:1393	Mutation altering degron motif	0.76
p.T1284I	SISO	cervix	COSMIC	ATTTS	DEG_SPOP_SBC_1	1293:1297	Mutation rewiring degron network	0.0833
p.V1412M	NCI-H1155	lung	COSMIC	ANSST	DEG_SPOP_SBC_1	1419:1423	Mutation rewiring degron network	0.1389
p.V1018L	KYSE-520	oesophagus	COSMIC	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation altering degron motif	0.6765
p.V1018L	KCL-22	haematopoietic and lymphoid tissue	COSMIC	PKSSS	DEG_SPOP_SBC_1	1015:1019	Mutation altering degron motif	0.6765
p.A766T	NCI-H128	lung	COSMIC	ASSSS	DEG_SPOP_SBC_1	772:776	Mutation rewiring degron network	0.1667
p.F1362I	PCI-30	upper aerodigestive tract	COSMIC	VSSSS	DEG_SPOP_SBC_1	1365:1369	Mutation rewiring degron network	0.25
p.V921I	NCI-H1693	lung	COSMIC	VSSSS	DEG_SPOP_SBC_1	907:911	Mutation rewiring degron network	0.0556
p.S1389L	BC-3	haematopoietic and lymphoid tissue	COSMIC	PNSSS	DEG_SPOP_SBC_1	1389:1393	Mutation altering degron motif	0.7667
p.C700Y	RPMI-2650	upper aerodigestive tract	COSMIC	IETPNKS	DEG_SCF_FBW7_1	697:703	Mutation altering degron motif	0.7087
p.V1185E	NCI-H1048	lung	COSMIC	AQTST	DEG_SPOP_SBC_1	1175:1179	Mutation rewiring degron network	0.1667

DegronMD: protein-targeted degradation, mutation and drug response to degrons

NUP153

UniProt ID: P49790

Entrez ID: 9972

Protein name: Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for NUP153 in