Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase

Found 139 literature records

Page :1 2 3
Entrez IDDescription
26524Identification of a tumor suppressor relay between the FOXP3 and the Hippo pathways in breast and prostate cancers.
50943Identification of a tumor suppressor relay between the FOXP3 and the Hippo pathways in breast and prostate cancers.
23671the tumor suppressor activity of TMEFF2 requires the cytoplasmic/transmembrane portion of the protein and correlates with its ability to bind to SARDH and to modulate the level of sarcosine.
5728Activation of tumor suppressor protein PTEN and induction of apoptosis are involved in cAMP-mediated inhibition of cell number in B92 glial cells.
406941miR-149 may play a role as tumor suppressor by targeting RAP1B
5101Our results suggest that PCDH9 might function as a tumor suppressor during cancer development and progression
55384MEG3 noncoding RNA: a tumor suppressor.
55384MEG3 noncoding RNA: a tumor suppressor. These lines of evidence strongly suggest that MEG3 functions as a novel lncRNA tumor suppressor.
619552miR-483-5p can serve as a tumor suppressor in gliomas
104"Findings demonstrate that post-transcriptional A-to-I RNA editing might be crucial for glioblastoma pathogenesis, identify ADAR2-editing enzyme as a candidate tumor suppressor gene and provide proof that ADAR2 may represent a suitable target."
4089"In vitro induction of TIAF1 self-association upregulated the expression of tumor suppressors Smad4 and WW domain-containing oxidoreductase (WOX1 or WWOX), and WOX1 in turn increased the TIAF1 expression."
407010"CREB promotes gliomagenesis and acts as a modulator of oncogenic mir-23a, which represses the tumor suppressor PTEN."
406901"p53-induced miR-107 suppresses brain tumor cell growth and down-regulates CDK6 and Notch-2 expression, supporting its tumor suppressor role and utility as a target for glioma therapy."
442900"results suggest that miR-326 is an important candidate tumor suppressor, and its down-regulated expression may contribute to glioma progression."
406924MiR-134 could play an important role as a tumor suppressor relying on its direct translational attenuation of Nanog
79648"in addition to its role in brain development, MCPH1 also functions as a tumor suppressor gene and is regulated by miR-27a"
4486"the function of RON in tumors may be multidimensional, not just as a tumor suppressor or oncogene."
5522PPP2R2C is a potential tumor suppressor gene in human brain cancers.
30845demonstrate Ehd3 growth inhibitory functions in glioma cells in vivo. We suggest that Ehd3 functions as a tumor suppressor gene and loss of its expression is a very common event in gliomas
574506miR-503 is a tumor suppressor for glioblastoma and a favorable factor against glioma progression through targeting IGF-1R.
406951Validation of the important role of miR-16 as a tumor suppressor gene in glioma growth and invasiveness.
406924Results identify miR-134 as a novel RTK-regulated tumor-suppressive hub that mediates RTK and RTK-inhibitor effects on GBM malignancy by controlling KRAS and STAT5B.
7982The tumor suppressor ST7 is a key gene silenced by PRMT5.
51548SIRT6 inhibits glioma cell proliferation and colony formation in vitro and glioma cell growth in vivo in a PCBP2 dependent manner. SIRT6 inhibits PCBP2 expression through deacetylating H3K9ac and SIRT6 acts as a tumor suppressor in glioma.
407043These data suggest that miR-7-5p functions as a tumor suppressor gene to regulate glioblastoma microvascular endothelial cell proliferation potentially by targeting the RAF1 oncogene
407044These data suggest that miR-7-5p functions as a tumor suppressor gene to regulate glioblastoma microvascular endothelial cell proliferation potentially by targeting the RAF1 oncogene
407045These data suggest that miR-7-5p functions as a tumor suppressor gene to regulate glioblastoma microvascular endothelial cell proliferation potentially by targeting the RAF1 oncogene
84446BRSK1 is a novel tumor suppressor in breast cancer which inversely correlated with Jab1 expression.
494332"In summary, this study suggested that miR-383 plays the role of tumor suppressor by targeting CCND1 in glioma cells, and may be useful for developing a new therapeutic strategy for gliomas."
406943miR-152 mediates the tumor-suppressive effects that knockdown of XIST exerts in glioblastoma stem cells.
1028"p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene."
1739"Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein."
7428"Expression of the Von Hippel-Lindau tumor suppressor gene, VHL, in human fetal kidney and during mouse embryogenesis."
1801"Identification of two candidate tumor suppressor genes on chromosome 17p13.3. Using allelic loss mapping and positional cloning methods, we have recently identified two novel genes, which we refer to as OVCA1 and OVCA2, that map to 17p13.3."
4897Fluorescence in situ hybridization maps the gene for human Bravo/Nr-CAM to human chromosome 7q31.1-q31.2. This chromosomal locus has been previously identified as containing a tumor suppressor candidate gene commonly deleted in certain human cancer tissues.
7428Improved detection of germline mutations in the von Hippel-Lindau disease tumor suppressor gene.
999The tumor-suppressor function of E-cadherin.
672cDNA sequence and chromosomal localization of mouse Dlgh3 gene adjacent to the BRCA1 tumor suppressor locus.
4763Region-specific astrogliosis in brains of mice heterozygous for mutations in the neurofibromatosis type 1 (Nf1) tumor suppressor.


')