Found 476 literature records

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Entrez ID	Description
3659	Data suggest that the dual effect of retinoids in increasing interferon regulatory factor-1 mRNA and nuclear protein may be essential for its tumor suppressor activity and immunosurveillance functions in breast epithelial cells.
2066	"results suggest that ErbB4 is not a potent, highly penetrant tumor suppressor, nor is it a factor in Neu-mediated tumorigenesis in this model"
1029	Tumor suppressor p16INK4A regulates polycomb-mediated DNA hypermethylation in human mammary epithelial cells.
10395	DLC1 appears to be a major tumor suppressor genes implicated in the pathogenesis of these tumors
8678	"Evolutionarily conserved domain of Beclin 1 is essential for Vps34 interaction, autophagy function, and tumor suppressor function."
57509	"Structural organization and expression of human MTUS1, a candidate 8p22 tumor suppressor gene encoding a family of angiotensin II AT2 receptor-interacting proteins, ATIP."
1474	Epigenetic silencing of the tumor suppressor cystatin M occurs during breast cancer progression.
672	"Role for BRCA1 in modulating estrogen biosynthesis in Adipose stem cells, contributing to its tissue-specific tumor suppressor function."
672	BRCA1 is a tumor suppressor gene and is known to be responsible for breast cancer and breast-ovarian cancers running in families.
2064	Introduction of p27(Kip1) is haploinsufficient for ErbB2 mammary tumor suppression in vivo and functions to repress collaborative oncogenic signals.
863	"ZNF652, a novel zinc finger protein, interacts with the putative breast tumor suppressor CBFA2T3 to repress transcription."
672	distinct single nucleotide changes in the BRCT domain of BRCA1 affect binding of this protein to the tumor suppressor p53
7157	distinct single nucleotide changes in the BRCT domain of BRCA1 affect binding of this protein to the tumor suppressor p53
10395	Expression profile of the tumor suppressor genes DLC-1 and DLC-2 in solid tumors.
90627	Expression profile of the tumor suppressor genes DLC-1 and DLC-2 in solid tumors.
253738	Expression of EBF3 resulted in cell cycle arrest and apoptosis. EBF3 regulates a transcriptional program underlying a putative tumor suppression pathway.
91608	RasL10B is a new member of Ras superfamily with tumor suppressor potential
3486	"Results showed that IGFBP-3 methylation played an important role in the silencing of its expression, suggesting that IGFBP-3 may act as a tumor suppressor gene in several human cancers examined."
1474	Cystatin M may encode a novel epigenetically inactivated candidate tumor suppressor gene.
5728	"[Contiguous gene deletion within chromosome arm 10q is associated with juvenile polyposis of infancy, reflecting cooperation between the BMPR1A and PTEN tumor-suppressor genes]."
2066	These data suggest that ErbB4 behaves as a mammary tumor suppressor and that loss of ErbB4 coupling to growth arrest may be an important event in mammary tumorigenesis.
7490	Isoforms of Wilms' tumor suppressor gene (WT1) have distinct effects on mammary epithelial cells.
5925	The retinoblastoma tumor suppressor modifies the therapeutic response of breast cancer.
57509	Copy number variant in the candidate tumor suppressor gene MTUS1 and familial breast cancer risk.
27330	"RT-PCR data show high expression of putative tumor suppressor genes Rsk4 and RbAp46 in 47% and 79% of breast carcinoma cases, respectively, whereas Cldn2 was down-regulated in 52% of breast cancer cases compared with normal adjacent tissues."
5931	"RT-PCR data show high expression of putative tumor suppressor genes Rsk4 and RbAp46 in 47% and 79% of breast carcinoma cases, respectively, whereas Cldn2 was down-regulated in 52% of breast cancer cases compared with normal adjacent tissues."
1003	"inactivation of Cdh1 and Cdh5 is likely to cooperate with the loss of p53, suggesting a possible tumor suppressive function of these genes in mammary carcinogenesis"
54756	Inhibitory effect of hSef on cell proliferation combined with consistent downregulation in human carcinoma indicates a tumor suppressor-like role for Sef.
5728	Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity.
8289	Genomic and functional evidence for an ARID1A tumor suppressor role.
55749	"CARP-1 is a suppressor of breast cancer growth, and its expression is diminished in tumors, in part, by methylation-dependent silencing"
1958	reveal a novel role for protein phosphatase 1 inhibitor in the regulation of the tumor suppressor gene EGR1 via activation of the MEK-ERK MAPK pathway
23221	Cyclin D1 down-regulation is essential for DBC2's tumor suppressor function.
7703	"Mel-18 and Bmi-1 may regulate the Akt pathway in breast cancer cells, and that Mel-18 functions as a tumor suppressor by repressing the expression of Bmi-1 and consequently down-regulating Akt activity."
164656	"Matriptase-2 suppresses breast tumor development in vivo, displays prognostic value for breast cancer patients, inhibits both breast cancer cell invasion and motility in vitro, and may play a contrasting role to matriptase-1 in breast cancer"
55743	CHFR has a role as a tumor suppressor in breast cancer
23582	P0 overexpression may cause tumorigenesis in breast and liver tissues at least in part by inhibiting GCIP-mediated tumor suppression.
7049	These data indicate that TbetaRIII acts as a tumor suppressor in nontumorigenic mammary epithelial cells at least in part by inhibiting NFkappaB-mediated repression of E-cadherin.
51741	Wwox hypomorphs had an increased incidence of B-cell lymphomas supports a role of Wwox as a tumor suppressor
580	Structural requirements for the BARD1 tumor suppressor in chromosomal stability and homology-directed DNA repair.
116173	"CMTM5 exhibits tumor suppressor activities, but with frequent epigenetic inactivation in carcinoma cell lines"
7490	The Wilms' tumor suppressor WT1 is associated with melanoma proliferation.
5728	[Inhibitory effects of tumor suppressor gene PTEN on proliferation and metastasis of breast cancer ZR-75-1 cells].
5728	"Cell cycle progression from the G(1) to the S phase is arrested in cells expressing wild-type PTEN, suggesting a role for PTEN as a tumor suppressor gene."
9538	Loss of putative tumor suppressor EI24/PIG8 confers resistance to etoposide.
5371	Degradation of the tumor suppressor PML by Pin1 contributes to the cancer phenotype of breast cancer MDA-MB-231 cells.
5728	Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair.
860	Runx2 functions as a tumor suppressor in primary diploid osteoblasts; subnuclear targeting contributes to Runx2-mediated tumor suppression.
675	Molecular genetic analysis of the BRCA2 tumor suppressor gene region in cutaneous squamous cell carcinomas.
22943	DKK-1 mediated tumor suppressor effect is independent of beta-catenin dependent transcription and a CamKII pathway contributes to DKK-1 signaling

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