Found 53 literature records

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Entrez ID	Description
10335	"Because other common integration sites in BXH2 leukemias encoding proto-oncogenes contain ecotropic rather than MRV viruses, it has been speculated that MRV viruses may selectively target tumor suppressor genes. "
4763	Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo.
51780	"A novel nuclear protein, 5qNCA is a candidate for the myeloid leukemia tumor suppressor gene on chromosome 5 band q31."
1050	may function as a tumor suppressor that is mutated during tumorigenesis. Abnormalties in C/EBPalpha function contribute to the development of malignancies in a variety of tisues.
5728	Negative feedback regulation of the tumor suppressor PTEN by phosphoinositide-induced serine phosphorylation.
1029	"The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia."
1029	ATM and the ARF-p53 tumor suppressor pathway may cooperate in the pathogenesis of diffuse large B-cell lymphoma
23087	"gene located on chromosome 8p21, a region implicated in leukemias and solid tumors; enforced expression inhibited cell growth, clonogenicity, and tumorigenicity; conceivable HLS5 is one of the tumor suppressor genes thought to reside at the 8p21 locus"
7474	Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue.
1030	review experiments and present examples of new models of myeloid leukemia where retroviruses have collaborated with a transgene [Cbfbeta-MYH111 from Inv(16)] and with loss of a tumor suppressor (Ink4b) mice to induce leukemia.
5371	Loss of the tumor suppressor PML in human cancers of multiple histologic origins.
1030	The interferon regulatory factor ICSBP/IRF-8 in combination with PU.1 up-regulates expression of tumor suppressor p15(Ink4b) in murine myeloid cells.
3400	Global assessment of promoter methylation in a mouse model of cancer identifies ID4 as a putative tumor-suppressor gene in human leukemia.
3394	Retroviral integration site analysis identifies ICSBP as a collaborating tumor suppressor gene in NUP98-TOP1-induced leukemia.
9314	The work identifies KLF4 as a putative tumor suppressor in B-cell malignancies.
1029	p16INK4A tumor suppressor gene expression and CD3epsilon deficiency but not pre-TCR deficiency inhibit TAL1-linked T-lineage leukemogenesis.
55294	"FBW7 is a novel tumor suppressor in T cell leukemia, and its loss may be a potential mechanism of drug resistance in T-ALL"
1029	ARF tumor suppressor has a role in mouse models of acute leukemias [review]
7490	The hDMP1 tumor suppressor is a new WT1 target in myeloid leukemias.
9988	The hDMP1 tumor suppressor is a new WT1 target in myeloid leukemias.
5925	The retinoblastoma tumor suppressor is a critical intrinsic regulator for hematopoietic stem and progenitor cells under stress.
634	Direct interaction of tumor suppressor CEACAM1 with beta catenin: identification of key residues in the long cytoplasmic domain.
139285	Tumor suppressor WTX gene mutation is rare in acute leukemias.
406986	"Expression of miR-203 reduces ABL1 and BCR-ABL1 fusion protein levels and inhibits tumor cell proliferation in an ABL1-dependent manner, suggesting it may function as a tumor suppressor."
23705	"These results suggest that the conspicuous expression of the tumor suppressor genes BEX2, IGSF4 and TIMP3 in MLLmu acute myeloid leukemias cell lines is the consequence of altered epigenetic properties of MLL fusion proteins."
7078	"These results suggest that the conspicuous expression of the tumor suppressor genes BEX2, IGSF4 and TIMP3 in MLLmu acute myeloid leukemias cell lines is the consequence of altered epigenetic properties of MLL fusion proteins."
84707	"These results suggest that the conspicuous expression of the tumor suppressor genes BEX2, IGSF4 and TIMP3 in MLLmu acute myeloid leukemias cell lines is the consequence of altered epigenetic properties of MLL fusion proteins."
5728	PTEN is a tumor suppressor in CML stem cells and BCR-ABL-induced leukemias in mice.
54790	"With diverse genetic methods, TET2 on chromosome 4q24 was identified as candidate tumor suppressor gene."
84295	these results identify PHF6 as a new X-linked tumor suppressor in T-ALL and point to a strong genetic interaction between PHF6 loss and aberrant expression of TLX transcription factors in the pathogenesis of this disease.
442920	Functional genomics of tumor suppressor miR-196b in T-cell acute lymphoblastic leukemia.
84295	PHF6 as a tumor suppressor gene mutated in acute myeloid leukemias (AML) and extend the role of this X-linked tumor suppressor gene in the pathogenesis of hematologic tumors.
5728	Secondary mutations attenuated this tumor suppressor response in some leukemias that arose after Pten deletion
9046	Mutational analysis of DOK2 tumor suppressor gene in acute leukemias.
1029	"Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies."
4851	"Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies."
406935	miR-143 functions as a tumor suppressor in MLL-AF4 B-cell acute lymphoblastic leukemia.
4221	data provide a structural basis for understanding the role of menin as a tumor suppressor protein and as an oncogenic co-factor of mixed lineage leukemia fusion proteins
23512	"study reports presence of loss-of-function mutations and deletions of the EZH2 and SUZ12 genes, which encode components of the Polycomb repressive complex 2 (PRC2), in 25% of T cell acute lymphoblastic leukemias; study suggesst tumor suppressor role for PRC2 in leukemia and suggest a gnized dynamic interplay between oncogenic NOTCH1 and PRC2"
2934	"Our work confirms that the cytoskeletal tumor suppressor, gelsolin, can induce monocytic myeloid differentiation in addition to growth retardation in the human monocytic cell line U937."
1523	"Data indicate CUX1 as a conserved, haploinsufficient tumor suppressor frequently deleted in myeloid neoplasms."
4849	"CNOT3 is a tumor suppressor mutated in 7 of 89 (7.9%) adult T-cell acute lymphoblastic leukemias, and its knockdown causes tumors in a sensitized Drosophila melanogaster model."
25792	CIZ1 functions as a tumor suppressor in vivo.
406942	findings show that miR-150 acts as a tumor suppressor through direct repression of multiple oncogenes in MLL-AF9-induced leukemias; miR-150 inhibits MLL-AF9 leukemic cell growth in vitro by induction of apoptosis and blocks the progression of MLL-AF9 leukemias in vivo
2146	"PRC2 is a tumor suppressor in Emicro-myc lymphomagenesis, because disease onset was accelerated by heterozygosity for Suz12 or by short hairpin RNA-mediated knockdown of Suz12 or Ezh2."
23512	"PRC2 is a tumor suppressor in Emicro-myc lymphomagenesis, because disease onset was accelerated by heterozygosity for Suz12 or by short hairpin RNA-mediated knockdown of Suz12 or Ezh2."
2145	"We show that, in contrast to PRC1, PRC2 is a tumor suppressor in Emicro-myc lymphomagenesis in lymphoma."
2146	"We show that, in contrast to PRC1, PRC2 is a tumor suppressor in Emicro-myc lymphomagenesis in lymphoma."
23512	"We show that, in contrast to PRC1, PRC2 is a tumor suppressor in Emicro-myc lymphomagenesis in lymphoma."
8726	"We show that, in contrast to PRC1, PRC2 is a tumor suppressor in Emicro-myc lymphomagenesis in lymphoma."

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