DegronMD

Uniprot ID: Q16363

Source protein: Laminin subunit alpha-4

Source gene: LAMA4

Class: DEG_APCC_KENBOX_2

Location: 358:362

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.7882

ASA_SCORE: 96.4

COIL: 0.1988

CONS_SCORE: 0.4501

DSS_SCORE: 0.4526

HELIX: 0.8012

FCONS_SCORE: 1.3264

RIG_SCORE: 0.7419

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Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
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Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8N3K9	Cardiomyopathy-associated protein 5	DEG_APCC_KENBOX_2	2540:2544	EKENQ	APC,CDC20,FZR1	0.8952	More...
P30519	Heme oxygenase 2	DEG_APCC_KENBOX_2	23:27	EKENQ	APC,CDC20,FZR1	0.713	More...
Q16363	Laminin subunit alpha-4	DEG_APCC_KENBOX_2	358:362	EKENQ	APC,CDC20,FZR1	0.7882	More...
P48681	Nestin	DEG_APCC_KENBOX_2	671:675	EKENQ	APC,CDC20,FZR1	0.5502	More...
P48681	Nestin	DEG_APCC_KENBOX_2	715:719	EKENQ	APC,CDC20,FZR1	0.9987	More...
Q15004	PCNA-associated factor	DEG_APCC_KENBOX_2	77:81	EKENQ	APC,CDC20,FZR1	0.9907	More...
Q9P219	Protein Daple	DEG_APCC_KENBOX_2	469:473	EKENQ	APC,CDC20,FZR1	0.7725	More...
Q5TD94	Radial spoke head protein 4 homolog A	DEG_APCC_KENBOX_2	10:14	EKENQ	APC,CDC20,FZR1	0.9404	More...
Q9BXT5	Testis-expressed protein 15	DEG_APCC_KENBOX_2	1186:1190	EKENQ	APC,CDC20,FZR1	0.993	More...

Showing 1 to 9 of 9 entries

DegronMD: protein-targeted degradation, mutation and drug response to degrons