DegronMD

Uniprot ID: P07359

Source protein: Platelet glycoprotein Ib alpha chain

Source gene: GP1BA

Class: DEG_SPOP_SBC_1

Location: 376:380

E3 ligase: SPOP

DEGRON score: 0.9058

ASA_SCORE: 100.18

COIL: 0.9392

CONS_SCORE: 0.344

DSS_SCORE: 0.7365

HELIX: 0.014

FCONS_SCORE: 1.0024

RIG_SCORE: 0.5658

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.T379I	DO233732	GACA	ICGC	PKSTT	DEG_SPOP_SBC_1	0.7078

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P07359	Platelet glycoprotein Ib alpha chain	DEG_SPOP_SBC_1	376:380	PKSTT	SPOP	0.9058	More...
Q14966	Zinc finger protein 638	DEG_SPOP_SBC_1	1518:1522	PKSTT	SPOP	0.7644	More...
Q52LJ0	Protein FAM98B	DEG_SPOP_SBC_1	160:164	PKSTT	SPOP	0.9796	More...
Q9BZW7	Testis-specific gene 10 protein	DEG_SPOP_SBC_1	89:93	PKSTT	SPOP	0.765	More...
Q9UMN6	Histone-lysine N-methyltransferase 2B	DEG_SPOP_SBC_1	515:519	PKSTT	SPOP	0.9463	More...
Q9Y2R2	Tyrosine-protein phosphatase non-receptor type 22	DEG_SPOP_SBC_1	329:333	PKSTT	SPOP	0.828	More...
Q5HYC2	Uncharacterized protein KIAA2026	DEG_SPOP_SBC_1	1324:1328	PKSTT	SPOP	0.9941	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons