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Gene Page: GSK3B

Summary

GeneID

2932

Symbol

GSK3B

Synonyms

Description

glycogen synthase kinase 3 beta

Locus tag

Gene type

protein-coding

Map location

3q13.3

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Association

A combined odds ratio method (Sun et al. 2008), association studies

Link to SZGene

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]

Click to show detail

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.4135

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

SLC2A4

0.68

0.60

SELENBP1

0.66

0.68

FAM107A

0.65

0.64

ACADS

0.65

0.68

ALDH1L1

0.65

0.64

CD40

0.65

0.58

CRYL1

0.64

0.73

ALDH2

0.63

0.51

FAH

0.62

0.67

C10orf54

0.62

0.59

Top 10 negatively co-expressed genes

STRBP

-0.46

-0.54

ARIH1

-0.46

-0.56

PURG

-0.45

-0.51

TMEM169

-0.45

-0.54

GFPT1

-0.45

-0.53

PAPD5

-0.45

-0.53

LEO1

-0.45

-0.52

RTF1

-0.45

-0.50

FAM32A

-0.44

-0.52

NOVA2

-0.44

-0.52

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0050321

tau-protein kinase activity

IEA

Brain (GO term level: 7)

GO:0000166

nucleotide binding

IEA

GO:0002039

p53 binding

IDA

14744935

GO:0004696

glycogen synthase kinase 3 activity

IDA

14744935

GO:0005524

ATP binding

IEA

GO:0016740

transferase activity

IEA

GO:0051059

NF-kappaB binding

IPI

15465828

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007242

intracellular signaling cascade

IDA

14749367

GO:0005977

glycogen metabolic process

TAS

7980435

GO:0006983

ER overload response

IDA

14744935

GO:0043066

negative regulation of apoptosis

IDA

14744935

GO:0018105

peptidyl-serine phosphorylation

IDA

11104755 |14744935

GO:0046827

positive regulation of protein export from nucleus

IDA

14744935

GO:0060070

Wnt receptor signaling pathway through beta-catenin

9601641

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005829

cytosol

EXP

8524413 |11955436 |12000790
|12820959 |15327769
|16753179

GO:0005634

nucleus

IDA

14744935

GO:0005737

cytoplasm

IDA

14744935

GO:0030877

beta-catenin destruction complex

IDA

9601641 |16188939

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ACLY	ACL \| ATPCL \| CLATP	ATP citrate lyase	Affinity Capture-MS	BioGRID	17353931
AKAP11	AKAP220 \| DKFZp781I12161 \| FLJ11304 \| KIAA0629 \| PRKA11	A kinase (PRKA) anchor protein 11	-	HPRD,BioGRID	12147701
AKT1	AKT \| MGC99656 \| PKB \| PKB-ALPHA \| PRKBA \| RAC \| RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1	AKT1 interacts with and phosphorylates GSK3B. This interaction was modelled on a demonstrated interaction between human AKT1 and GSK3B from an unspecified species.	BIND	15688030
AKT1	AKT \| MGC99656 \| PKB \| PKB-ALPHA \| PRKBA \| RAC \| RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1	Reconstituted Complex	BioGRID	16009706
AKT2	PKBB \| PKBBETA \| PRKBB \| RAC-BETA	v-akt murine thymoma viral oncogene homolog 2	-	HPRD,BioGRID	12434148
APC	BTPS2 \| DP2 \| DP2.5 \| DP3 \| GS	adenomatous polyposis coli	Affinity Capture-Western	BioGRID	11251183
AR	AIS \| DHTR \| HUMARA \| KD \| NR3C4 \| SBMA \| SMAX1 \| TFM	androgen receptor	Affinity Capture-Western Reconstituted Complex	BioGRID	15178691
AXIN1	AXIN \| MGC52315	axin 1	Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	9734785 \|12511557
AXIN2	AXIL \| DKFZp781B0869 \| MGC10366 \| MGC126582	axin 2	-	HPRD,BioGRID	10966653
BCL3	BCL4 \| D19S37	B-cell CLL/lymphoma 3	GSK3-beta interacts with and phosphorylates BCL-3.	BIND	15469820
BXDC1	FLJ21087 \| RPF2 \| bA397G5.4	brix domain containing 1	Affinity Capture-MS	BioGRID	17353931
C14orf129	GSKIP \| HSPC210 \| MGC4945	chromosome 14 open reading frame 129	Affinity Capture-MS	BioGRID	17353931
CCNE1	CCNE	cyclin E1	Biochemical Activity	BioGRID	14536078
CTNNB1	CTNNB \| DKFZp686D02253 \| FLJ25606 \| FLJ37923	catenin (cadherin-associated protein), beta 1, 88kDa	GSK3B (GSK3-Beta) interacts with and phosphorylates CTNNB1 (Beta-catenin).	BIND	15829978
CTNNB1	CTNNB \| DKFZp686D02253 \| FLJ25606 \| FLJ37923	catenin (cadherin-associated protein), beta 1, 88kDa	Affinity Capture-Western Biochemical Activity	BioGRID	10330181 \|11251183
DDX20	DKFZp434H052 \| DP103 \| GEMIN3	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20	Affinity Capture-MS	BioGRID	17353931
DHX36	DDX36 \| G4R1 \| KIAA1488 \| MLEL1 \| RHAU	DEAH (Asp-Glu-Ala-His) box polypeptide 36	Affinity Capture-MS	BioGRID	17353931
DNM1L	DLP1 \| DRP1 \| DVLP \| DYMPLE \| DYNIV-11 \| FLJ41912 \| HDYNIV \| VPS1	dynamin 1-like	-	HPRD,BioGRID	9731200
DVL1	DVL \| MGC54245	dishevelled, dsh homolog 1 (Drosophila)	-	HPRD	10428961
EWSR1	EWS	Ewing sarcoma breakpoint region 1	Affinity Capture-MS	BioGRID	17353931
FRAT1	FLJ97193	frequently rearranged in advanced T-cell lymphomas	-	HPRD	12095675
FRAT2	MGC10562	frequently rearranged in advanced T-cell lymphomas 2	-	HPRD	11738041
GEMIN4	DKFZp434B131 \| DKFZp434D174 \| HC56 \| HCAP1 \| HHRF-1 \| p97	gem (nuclear organelle) associated protein 4	Affinity Capture-MS	BioGRID	17353931
GSK3B	-	glycogen synthase kinase 3 beta	-	HPRD	14529625
IGF2BP1	CRD-BP \| CRDBP \| IMP-1 \| IMP1 \| VICKZ1 \| ZBP1	insulin-like growth factor 2 mRNA binding protein 1	Affinity Capture-MS	BioGRID	17353931
ILK	DKFZp686F1765 \| P59	integrin-linked kinase	-	HPRD	9736715
MAPT	DDPAC \| FLJ31424 \| FTDP-17 \| MAPTL \| MGC138549 \| MSTD \| MTBT1 \| MTBT2 \| PPND \| TAU	microtubule-associated protein tau	GSK3beta phosphorylates Ftau.This interaction was modelled on a demonstrated interaction between rabbit GSK3beta and human Ftau.	BIND	14636947
MUC1	CD227 \| EMA \| H23AG \| MAM6 \| PEM \| PEMT \| PUM	mucin 1, cell surface associated	-	HPRD,BioGRID	9819408
NCOA3	ACTR \| AIB-1 \| AIB1 \| CAGH16 \| CTG26 \| KAT13B \| MGC141848 \| RAC3 \| SRC3 \| TNRC14 \| TNRC16 \| TRAM-1 \| pCIP	nuclear receptor coactivator 3	SRC-3 interacts with and is phosphorylated by GSK3-beta.	BIND	15383283
NFKB1	DKFZp686C01211 \| EBP-1 \| KBF1 \| MGC54151 \| NF-kappa-B \| NFKB-p105 \| NFKB-p50 \| p105	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	-	HPRD,BioGRID	11425860
NIN	KIAA1565	ninein (GSK3B interacting protein)	-	HPRD,BioGRID	11004522
NOTCH1	TAN1 \| hN1	Notch homolog 1, translocation-associated (Drosophila)	-	HPRD,BioGRID	12123574
NOTCH2	AGS2 \| hN2	Notch homolog 2 (Drosophila)	-	HPRD,BioGRID	12794074
OGT	FLJ23071 \| HRNT1 \| MGC22921 \| O-GLCNAC	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	-	HPRD	10753899
PPP1CA	MGC15877 \| MGC1674 \| PP-1A \| PPP1A	protein phosphatase 1, catalytic subunit, alpha isoform	Affinity Capture-Western	BioGRID	12147701
PPYR1	MGC116897 \| NPY4-R \| NPY4R \| PP1 \| Y4	pancreatic polypeptide receptor 1	-	HPRD	12147701
PRKAR2A	MGC3606 \| PKR2 \| PRKAR2	protein kinase, cAMP-dependent, regulatory, type II, alpha	Affinity Capture-Western	BioGRID	12147701
PRKCA	AAG6 \| MGC129900 \| MGC129901 \| PKC-alpha \| PKCA \| PRKACA	protein kinase C, alpha	Biochemical Activity	BioGRID	1324914
PRKCB	MGC41878 \| PKC-beta \| PKCB \| PRKCB1 \| PRKCB2	protein kinase C, beta	-	HPRD	1324914
PRKCD	MAY1 \| MGC49908 \| PKCD \| nPKC-delta	protein kinase C, delta	PKC-delta interacts with and phosphorylates GSK3-beta. This interaction was modeled on a demonstrated interaction between human PKC-delta and rabbit GSK3-beta.	BIND	15824731
PTK2	FADK \| FAK \| FAK1 \| pp125FAK	PTK2 protein tyrosine kinase 2	-	HPRD,BioGRID	11809746
PTPN1	PTP1B	protein tyrosine phosphatase, non-receptor type 1	-	HPRD,BioGRID	7514173
SF3B1	PRP10 \| PRPF10 \| SAP155 \| SF3b155	splicing factor 3b, subunit 1, 155kDa	Affinity Capture-MS	BioGRID	17353931
SGK3	CISK \| DKFZp781N0293 \| SGK2 \| SGKL	serum/glucocorticoid regulated kinase family, member 3	-	HPRD,BioGRID	12054501
SMN2	BCD541 \| C-BCD541 \| FLJ76644 \| MGC20996 \| MGC5208 \| SMNC	survival of motor neuron 2, centromeric	Affinity Capture-MS	BioGRID	17353931
SMYD2	HSKM-B \| KMT3C \| MGC119305 \| ZMYND14	SET and MYND domain containing 2	Affinity Capture-MS	BioGRID	17353931
SNAI1	SLUGH2 \| SNA \| SNAH \| dJ710H13.1	snail homolog 1 (Drosophila)	Snail interacts with GSK-3beta.	BIND	15448698
SNRNP70	RNPU1Z \| RPU1 \| SNRP70 \| U170K \| U1AP \| U1RNP	small nuclear ribonucleoprotein 70kDa (U1)	Affinity Capture-MS	BioGRID	17353931
STRAP	MAWD \| PT-WD \| UNRIP	serine/threonine kinase receptor associated protein	Affinity Capture-MS	BioGRID	17353931
TP53	FLJ92943 \| LFS1 \| TRP53 \| p53	tumor protein p53	p53 interacts with GSK3-beta.	BIND	12048243
TP53	FLJ92943 \| LFS1 \| TRP53 \| p53	tumor protein p53	-	HPRD,BioGRID	12048243
TPPP	TPPP/p25 \| TPPP1 \| p24 \| p25 \| p25alpha	tubulin polymerization promoting protein	-	HPRD	11781156
TSC1	KIAA0243 \| LAM \| MGC86987 \| TSC	tuberous sclerosis 1	Affinity Capture-Western	BioGRID	12511557
TSC2	FLJ43106 \| LAM \| TSC4	tuberous sclerosis 2	Affinity Capture-Western Biochemical Activity	BioGRID	12511557 \|16959574
UPF3A	HUPF3A \| RENT3A \| UPF3	UPF3 regulator of nonsense transcripts homolog A (yeast)	-	HPRD,BioGRID	15231747
XPO6	EXP6 \| FLJ22519 \| KIAA0370 \| RANBP20	exportin 6	Affinity Capture-MS	BioGRID	17353931

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
KEGG_ERBB_SIGNALING_PATHWAY	87	71	All SZGR genes in this pathway
KEGG_CHEMOKINE_SIGNALING_PATHWAY	190	128	All SZGR genes in this pathway
KEGG_CELL_CYCLE	128	84	All SZGR genes in this pathway
KEGG_WNT_SIGNALING_PATHWAY	151	112	All SZGR genes in this pathway
KEGG_HEDGEHOG_SIGNALING_PATHWAY	56	42	All SZGR genes in this pathway
KEGG_AXON_GUIDANCE	129	103	All SZGR genes in this pathway
KEGG_FOCAL_ADHESION	201	138	All SZGR genes in this pathway
KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY	108	89	All SZGR genes in this pathway
KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY	75	56	All SZGR genes in this pathway
KEGG_NEUROTROPHIN_SIGNALING_PATHWAY	126	103	All SZGR genes in this pathway
KEGG_INSULIN_SIGNALING_PATHWAY	137	103	All SZGR genes in this pathway
KEGG_MELANOGENESIS	102	80	All SZGR genes in this pathway
KEGG_ALZHEIMERS_DISEASE	169	110	All SZGR genes in this pathway
KEGG_PATHWAYS_IN_CANCER	328	259	All SZGR genes in this pathway
KEGG_COLORECTAL_CANCER	62	47	All SZGR genes in this pathway
KEGG_ENDOMETRIAL_CANCER	52	45	All SZGR genes in this pathway
KEGG_PROSTATE_CANCER	89	75	All SZGR genes in this pathway
KEGG_BASAL_CELL_CARCINOMA	55	44	All SZGR genes in this pathway
BIOCARTA_ALK_PATHWAY	37	29	All SZGR genes in this pathway
BIOCARTA_G1_PATHWAY	28	21	All SZGR genes in this pathway
BIOCARTA_P35ALZHEIMERS_PATHWAY	11	9	All SZGR genes in this pathway
BIOCARTA_GSK3_PATHWAY	27	26	All SZGR genes in this pathway
BIOCARTA_PITX2_PATHWAY	15	15	All SZGR genes in this pathway
BIOCARTA_NFAT_PATHWAY	56	45	All SZGR genes in this pathway
BIOCARTA_PTDINS_PATHWAY	23	16	All SZGR genes in this pathway
BIOCARTA_PS1_PATHWAY	14	14	All SZGR genes in this pathway
BIOCARTA_EIF2_PATHWAY	11	8	All SZGR genes in this pathway
BIOCARTA_IGF1MTOR_PATHWAY	20	14	All SZGR genes in this pathway
BIOCARTA_SHH_PATHWAY	16	15	All SZGR genes in this pathway
BIOCARTA_WNT_PATHWAY	26	24	All SZGR genes in this pathway
SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES	67	54	All SZGR genes in this pathway
SIG_IL4RECEPTOR_IN_B_LYPHOCYTES	27	23	All SZGR genes in this pathway
WNT_SIGNALING	89	71	All SZGR genes in this pathway
SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES	51	41	All SZGR genes in this pathway
SIG_BCR_SIGNALING_PATHWAY	46	38	All SZGR genes in this pathway
ST_WNT_BETA_CATENIN_PATHWAY	34	28	All SZGR genes in this pathway
ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY	37	29	All SZGR genes in this pathway
PID_LYSOPHOSPHOLIPID_PATHWAY	66	53	All SZGR genes in this pathway
PID_BETA_CATENIN_DEG_PATHWAY	18	17	All SZGR genes in this pathway
PID_REELIN_PATHWAY	29	29	All SZGR genes in this pathway
PID_PS1_PATHWAY	46	39	All SZGR genes in this pathway
PID_ILK_PATHWAY	45	32	All SZGR genes in this pathway
PID_CDC42_PATHWAY	70	51	All SZGR genes in this pathway
PID_LKB1_PATHWAY	47	37	All SZGR genes in this pathway
PID_WNT_CANONICAL_PATHWAY	20	18	All SZGR genes in this pathway
PID_NFAT_3PATHWAY	54	47	All SZGR genes in this pathway
PID_REG_GR_PATHWAY	82	60	All SZGR genes in this pathway
PID_MYC_PATHWAY	25	22	All SZGR genes in this pathway
PID_AR_TF_PATHWAY	53	38	All SZGR genes in this pathway
PID_BMP_PATHWAY	42	31	All SZGR genes in this pathway
PID_HEDGEHOG_GLI_PATHWAY	48	35	All SZGR genes in this pathway
PID_KIT_PATHWAY	52	40	All SZGR genes in this pathway
PID_DELTA_NP63_PATHWAY	47	34	All SZGR genes in this pathway
PID_AURORA_A_PATHWAY	31	20	All SZGR genes in this pathway
PID_INSULIN_GLUCOSE_PATHWAY	26	24	All SZGR genes in this pathway
PID_PI3KCI_AKT_PATHWAY	35	30	All SZGR genes in this pathway
PID_P53_REGULATION_PATHWAY	59	50	All SZGR genes in this pathway
PID_PI3K_PLC_TRK_PATHWAY	36	31	All SZGR genes in this pathway
WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_DN	92	51	All SZGR genes in this pathway
GARY_CD5_TARGETS_UP	473	314	All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP	485	293	All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_UP	418	263	All SZGR genes in this pathway
SENESE_HDAC1_TARGETS_UP	457	269	All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_UP	501	327	All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP	544	308	All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP	722	443	All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN	485	334	All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN	1781	1082	All SZGR genes in this pathway
DARWICHE_SKIN_TUMOR_PROMOTER_UP	142	96	All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_LOW_DN	165	107	All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_HIGH_UP	147	101	All SZGR genes in this pathway
DARWICHE_SQUAMOUS_CELL_CARCINOMA_UP	146	104	All SZGR genes in this pathway
GALLUZZI_PERMEABILIZE_MITOCHONDRIA	43	31	All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	855	609	All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	483	336	All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	811	508	All SZGR genes in this pathway
BENPORATH_SOX2_TARGETS	734	436	All SZGR genes in this pathway
BENPORATH_MYC_TARGETS_WITH_EBOX	230	156	All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP	195	138	All SZGR genes in this pathway
SHIN_B_CELL_LYMPHOMA_CLUSTER_7	27	22	All SZGR genes in this pathway
FERNANDEZ_BOUND_BY_MYC	182	116	All SZGR genes in this pathway
THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN	225	163	All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP	390	242	All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP	1691	1088	All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C5	46	36	All SZGR genes in this pathway
DURCHDEWALD_SKIN_CARCINOGENESIS_DN	264	168	All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_UP	673	430	All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_DN	593	372	All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_UP	601	369	All SZGR genes in this pathway
DAIRKEE_CANCER_PRONE_RESPONSE_BPA_E2	118	65	All SZGR genes in this pathway
GRADE_COLON_AND_RECTAL_CANCER_UP	285	167	All SZGR genes in this pathway
WANG_TUMOR_INVASIVENESS_DN	210	128	All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP	1305	895	All SZGR genes in this pathway
MILI_PSEUDOPODIA_CHEMOTAXIS_DN	457	302	All SZGR genes in this pathway
DANG_BOUND_BY_MYC	1103	714	All SZGR genes in this pathway
CHANDRAN_METASTASIS_UP	221	135	All SZGR genes in this pathway
MOOTHA_GLYCOGEN_METABOLISM	21	16	All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_PRONEURAL	177	132	All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN	1972	1213	All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D	280	158	All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE	1137	655	All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	1080	713	All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D	658	397	All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A	770	480	All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_UP	279	155	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-199	61	67	m8	hsa-miR-199a	CCCAGUGUUCAGACUACCUGUUC
miR-199	61	67	m8	hsa-miR-199b	CCCAGUGUUUAGACUAUCUGUUC
miR-26	41	47	m8	hsa-miR-26a^brain	UUCAAGUAAUCCAGGAUAGGC
miR-26	41	47	m8	hsa-miR-26b^SZ	UUCAAGUAAUUCAGGAUAGGUU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.