Gene Page: SOX4

Summary
GeneID  6659
Symbol  SOX4
Synonyms  EVI16
Description  SRY (sex determining region Y)-box 4
See related  HGNC:11200|MIM:184430|Ensembl:ENSG00000124766|HPRD:01695|
Locus tag  -
Gene type  protein-coding
Map location  6p22.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.033 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityTAS8268656 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006350transcriptionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
SDCBPMDA-9 | ST1 | SYCL | TACIP18syndecan binding protein (syntenin)-HPRD,BioGRID11498591 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP 285181All SZGR genes in this pathway
LIU_PROSTATE_CANCER_UP 9657All SZGR genes in this pathway
LIU_SOX4_TARGETS_UP 13794All SZGR genes in this pathway
FOURNIER_ACINAR_DEVELOPMENT_LATE_UP 116All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP 294178All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP 579346All SZGR genes in this pathway
PUIFFE_INVASION_INHIBITED_BY_ASCITES_DN 14591All SZGR genes in this pathway
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREY_DN 7444All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP 182110All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP 15791All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP 194122All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP 175108All SZGR genes in this pathway
AKL_HTLV1_INFECTION_UP 2716All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_GRANULOCYTE_UP 159All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP 185126All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_GRANULOCYTE_UP 5534All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP 204140All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP 157104All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_MONOCYTE_UP 2115All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP 4430All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN 329219All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
HAHTOLA_MYCOSIS_FUNGOIDES_SKIN_UP 177113All SZGR genes in this pathway
LANDIS_BREAST_CANCER_PROGRESSION_UP 4427All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP 552347All SZGR genes in this pathway
VANHARANTA_UTERINE_FIBROID_UP 4526All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
LANDIS_ERBB2_BREAST_TUMORS_324_UP 15093All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_4_5WK_UP 271175All SZGR genes in this pathway
LUI_THYROID_CANCER_PAX8_PPARG_UP 4429All SZGR genes in this pathway
HAMAI_APOPTOSIS_VIA_TRAIL_DN 186107All SZGR genes in this pathway
STREICHER_LSM1_TARGETS_UP 4434All SZGR genes in this pathway
DARWICHE_PAPILLOMA_PROGRESSION_RISK 7444All SZGR genes in this pathway
RIZ_ERYTHROID_DIFFERENTIATION_HBZ 4127All SZGR genes in this pathway
RIZ_ERYTHROID_DIFFERENTIATION_HEMGN 3121All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_2 12792All SZGR genes in this pathway
LI_AMPLIFIED_IN_LUNG_CANCER 178108All SZGR genes in this pathway
LUI_THYROID_CANCER_CLUSTER_1 5133All SZGR genes in this pathway
AIYAR_COBRA1_TARGETS_DN 2918All SZGR genes in this pathway
DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_DN 3627All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN 514319All SZGR genes in this pathway
FURUKAWA_DUSP6_TARGETS_PCI35_UP 7432All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1 229137All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2 153102All SZGR genes in this pathway
TOMLINS_PROSTATE_CANCER_UP 4027All SZGR genes in this pathway
NAKAYAMA_FRA2_TARGETS 4327All SZGR genes in this pathway
LIAO_METASTASIS 539324All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN 514330All SZGR genes in this pathway
SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_DN 4533All SZGR genes in this pathway
BENPORATH_ES_CORE_NINE_CORRELATED 10068All SZGR genes in this pathway
AMIT_SERUM_RESPONSE_60_MCF10A 5742All SZGR genes in this pathway
SHIN_B_CELL_LYMPHOMA_CLUSTER_8 3628All SZGR genes in this pathway
MORI_MATURE_B_LYMPHOCYTE_DN 7543All SZGR genes in this pathway
SHIPP_DLBCL_CURED_VS_FATAL_UP 3922All SZGR genes in this pathway
SWEET_KRAS_TARGETS_UP 8451All SZGR genes in this pathway
OKUMURA_INFLAMMATORY_RESPONSE_LPS 183115All SZGR genes in this pathway
MANALO_HYPOXIA_UP 207145All SZGR genes in this pathway
SANSOM_APC_TARGETS_UP 12684All SZGR genes in this pathway
MATSUDA_NATURAL_KILLER_DIFFERENTIATION 475313All SZGR genes in this pathway
BROWN_MYELOID_CELL_DEVELOPMENT_DN 12986All SZGR genes in this pathway
LENAOUR_DENDRITIC_CELL_MATURATION_UP 11484All SZGR genes in this pathway
KUMAR_TARGETS_OF_MLL_AF9_FUSION 405264All SZGR genes in this pathway
GENTILE_UV_LOW_DOSE_UP 2719All SZGR genes in this pathway
RHODES_CANCER_META_SIGNATURE 6447All SZGR genes in this pathway
NIELSEN_GIST_VS_SYNOVIAL_SARCOMA_UP 1912All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_SCC_DN 12386All SZGR genes in this pathway
GERHOLD_ADIPOGENESIS_DN 6444All SZGR genes in this pathway
HAN_JNK_SINGALING_UP 3521All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR 681420All SZGR genes in this pathway
ZAMORA_NOS2_TARGETS_DN 9671All SZGR genes in this pathway
WELCSH_BRCA1_TARGETS_DN 14192All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
GAVIN_FOXP3_TARGETS_CLUSTER_P3 160103All SZGR genes in this pathway
SANSOM_APC_TARGETS 212121All SZGR genes in this pathway
SANSOM_APC_MYC_TARGETS 217138All SZGR genes in this pathway
SANSOM_APC_TARGETS_REQUIRE_MYC 210123All SZGR genes in this pathway
SANSOM_WNT_PATHWAY_REQUIRE_MYC 5843All SZGR genes in this pathway
HELLER_HDAC_TARGETS_UP 317208All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP 461298All SZGR genes in this pathway
CLAUS_PGR_POSITIVE_MENINGIOMA_DN 1210All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_UP 673430All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_UP 602364All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_UP 601369All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_DN 258160All SZGR genes in this pathway
MASSARWEH_RESPONSE_TO_ESTRADIOL 6147All SZGR genes in this pathway
WALLACE_PROSTATE_CANCER_UP 2014All SZGR genes in this pathway
WHITEFORD_PEDIATRIC_CANCER_MARKERS 11663All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP 425298All SZGR genes in this pathway
PODAR_RESPONSE_TO_ADAPHOSTIN_UP 14798All SZGR genes in this pathway
BLUM_RESPONSE_TO_SALIRASIB_DN 342220All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_C_D_UP 13995All SZGR genes in this pathway
PARK_APL_PATHOGENESIS_UP 1411All SZGR genes in this pathway
RUIZ_TNC_TARGETS_UP 153107All SZGR genes in this pathway
MUELLER_COMMON_TARGETS_OF_AML_FUSIONS_UP 1410All SZGR genes in this pathway
LEE_RECENT_THYMIC_EMIGRANT 227128All SZGR genes in this pathway
HAN_SATB1_TARGETS_UP 395249All SZGR genes in this pathway
TAVAZOIE_METASTASIS 10868All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP 178108All SZGR genes in this pathway
COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP 10968All SZGR genes in this pathway
ASGHARZADEH_NEUROBLASTOMA_POOR_SURVIVAL_DN 4630All SZGR genes in this pathway
KOBAYASHI_EGFR_SIGNALING_24HR_UP 10165All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_UP 207143All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
CHANDRAN_METASTASIS_UP 221135All SZGR genes in this pathway
GERHOLD_RESPONSE_TO_TZD_DN 1311All SZGR genes in this pathway
DASU_IL6_SIGNALING_UP 5944All SZGR genes in this pathway
LI_INDUCED_T_TO_NATURAL_KILLER_DN 11683All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_DN 841431All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_PRONEURAL 177132All SZGR genes in this pathway
CHICAS_RB1_TARGETS_LOW_SERUM 10051All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN 505328All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP 259159All SZGR genes in this pathway
PASINI_SUZ12_TARGETS_DN 315215All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_DN 553343All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_TOP20_DN 1812All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN 321200All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_UP 344215All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D 658397All SZGR genes in this pathway
LOPEZ_TRANSLATION_VIA_FN1_SIGNALING 3521All SZGR genes in this pathway
PHONG_TNF_RESPONSE_NOT_VIA_P38 337236All SZGR genes in this pathway
PECE_MAMMARY_STEM_CELL_UP 14675All SZGR genes in this pathway
ZWANG_EGF_INTERVAL_DN 214124All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-129-5p23542360m8hsa-miR-129brainCUUUUUGCGGUCUGGGCUUGC
hsa-miR-129-5pCUUUUUGCGGUCUGGGCUUGCU
hsa-miR-129brainCUUUUUGCGGUCUGGGCUUGC
hsa-miR-129-5pCUUUUUGCGGUCUGGGCUUGCU
hsa-miR-129brainCUUUUUGCGGUCUGGGCUUGC
hsa-miR-129-5pCUUUUUGCGGUCUGGGCUUGCU
hsa-miR-129brainCUUUUUGCGGUCUGGGCUUGC
hsa-miR-129-5pCUUUUUGCGGUCUGGGCUUGCU
miR-130/30120972103m8hsa-miR-130abrainCAGUGCAAUGUUAAAAGGGCAU
hsa-miR-301CAGUGCAAUAGUAUUGUCAAAGC
hsa-miR-130bbrainCAGUGCAAUGAUGAAAGGGCAU
hsa-miR-454-3pUAGUGCAAUAUUGCUUAUAGGGUUU
miR-132/21211481154m8hsa-miR-212SZUAACAGUCUCCAGUCACGGCC
hsa-miR-132brainUAACAGUCUACAGCCAUGGUCG
miR-133131413201Ahsa-miR-133aUUGGUCCCCUUCAACCAGCUGU
hsa-miR-133bUUGGUCCCCUUCAACCAGCUA
miR-13812331239m8hsa-miR-138brainAGCUGGUGUUGUGAAUC
miR-140208320901A,m8hsa-miR-140brainAGUGGUUUUACCCUAUGGUAG
hsa-miR-140brainAGUGGUUUUACCCUAUGGUAG
miR-17-5p/20/93.mr/106/519.d20992105m8hsa-miR-17-5pCAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrainUAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106aAAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZUAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZCAAAGUGCUCAUAGUGCAGGUAG
hsa-miR-519dCAAAGUGCCUCCCUUUAGAGUGU
miR-18820582064m8hsa-miR-188CAUCCCUUGCAUGGUGGAGGGU
miR-1920962102m8hsa-miR-19aUGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19bUGUGCAAAUCCAUGCAAAACUGA
miR-191242524321A,m8hsa-miR-191brainCAACGGAAUCCCAAAAGCAGCU
miR-199213521411Ahsa-miR-199aCCCAGUGUUCAGACUACCUGUUC
hsa-miR-199bCCCAGUGUUUAGACUAUCUGUUC
miR-204/21120572063m8hsa-miR-204brainUUCCCUUUGUCAUCCUAUGCCU
hsa-miR-211UUCCCUUUGUCAUCCUUCGCCU
miR-208249725031Ahsa-miR-208AUAAGACGAGCAAAAAGCUUGU
miR-25/32/92/363/367247224791A,m8hsa-miR-25brainCAUUGCACUUGUCUCGGUCUGA
hsa-miR-32UAUUGCACAUUACUAAGUUGC
hsa-miR-92UAUUGCACUUGUCCCGGCCUG
hsa-miR-367AAUUGCACUUUAGCAAUGGUGA
hsa-miR-92bSZUAUUGCACUCGUCCCGGCCUC
miR-299-5p208120881A,m8hsa-miR-299-5pUGGUUUACCGUCCCACAUACAU
hsa-miR-299-5pUGGUUUACCGUCCCACAUACAU
miR-30-5p186418711A,m8hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-320207020761Ahsa-miR-320AAAAGCUGGGUUGAGAGGGCGAA
miR-329236523711Ahsa-miR-329brainAACACACCUGGUUAACCUCUUU
miR-338128912951Ahsa-miR-338brainUCCAGCAUCAGUGAUUUUGUUGA
miR-34/44925752581m8hsa-miR-34abrainUGGCAGUGUCUUAGCUGGUUGUU
hsa-miR-34cAGGCAGUGUAGUUAGCUGAUUGC
hsa-miR-449UGGCAGUGUAUUGUUAGCUGGU
hsa-miR-449bAGGCAGUGUAUUGUUAGCUGGC
miR-34b25762582m8hsa-miR-34bUAGGCAGUGUCAUUAGCUGAUUG
miR-369-3p234223491A,m8hsa-miR-369-3pAAUAAUACAUGGUUGAUCUUU
miR-374234323501A,m8hsa-miR-374UUAUAAUACAACCUGAUAAGUG
miR-38121942200m8hsa-miR-381UAUACAAGGGCAAGCUCUCUGU
miR-411248224881Ahsa-miR-411AACACGGUCCACUAACCCUCAGU
miR-450235423601Ahsa-miR-450UUUUUGCGAUGUGUUCCUAAUA
hsa-miR-450UUUUUGCGAUGUGUUCCUAAUA
hsa-miR-450UUUUUGCGAUGUGUUCCUAAUA
miR-499249725031Ahsa-miR-499UUAAGACUUGCAGUGAUGUUUAA
miR-539172617321Ahsa-miR-539GGAGAAAUUAUCCUUGGUGUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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