SZGR2

Summary ?

GeneID	991
Symbol	CDC20
Synonyms	CDC20A\|bA276H19.3\|p55CDC
Description	cell division cycle 20
Reference	MIM:603618\|HGNC:HGNC:1723\|Ensembl:ENSG00000117399\|HPRD:04686\|Vega:OTTHUMG00000007420
Gene type	protein-coding
Map location	1p34.1
Pascal p-value	4.865E-5
Sherlock p-value	0.91
Fetal beta	2.407
eGene	Myers' cis & trans

Gene in Data Sources

Gene set name	Method of gene set	Description	Info
CV:PGCnp	Genome-wide Association Study	GWAS
PMID:cooccur	High-throughput literature-search	Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
Literature	High-throughput literature-search	Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias	Click to show details
Network	Shortest path distance of core genes in the Human protein-protein interaction network	Contribution to shortest path in PPI network: 0.0167

Section I. Genetics and epigenetics annotation

eQTL annotation

SNP ID	Chromosome	Position	eGene	Gene Entrez ID	qvalue	eQTL type
rs2059443	chr2	34308478	CDC20	991	0.19	trans
rs5003961	chr7	78072443	CDC20	991	0.17	trans
rs4515471	chr7	78072585	CDC20	991	0.17	trans
rs10259327	chr7	78074924	CDC20	991	0.17	trans
rs6991445	chr8	75032923	CDC20	991	0.08	trans
rs16924550	chr12	22174951	CDC20	991	0.1	trans
rs11848694	chr14	34320757	CDC20	991	0.01	trans
rs16979902	chrX	140953782	CDC20	991	0.1	trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
SLC25A46	0.90	0.90
PJA2	0.89	0.91
SLC30A9	0.89	0.90
C5orf22	0.89	0.90
PPP6C	0.89	0.90
ACTR2	0.89	0.90
IPO11	0.89	0.91
OPA1	0.89	0.90
KIAA1012	0.88	0.90
CUL5	0.88	0.91

Top 10 negatively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
HIGD1B	-0.65	-0.66
FXYD1	-0.64	-0.66
GSDMD	-0.62	-0.65
MT-CO2	-0.62	-0.62
AF347015.21	-0.60	-0.59
IFI27	-0.60	-0.64
AF347015.2	-0.60	-0.58
AF347015.33	-0.59	-0.60
AF347015.8	-0.59	-0.60
AC098691.2	-0.59	-0.61

Section III. Gene Ontology annotation

Molecular function	GO term	Evidence	Neuro keywords	PubMed ID
GO:0005515	protein binding	IPI		11030144 \|14743218 \|17353931 \|17719540 \|18022367
Biological process	GO term	Evidence	Neuro keywords	PubMed ID
GO:0006511	ubiquitin-dependent protein catabolic process	TAS		9682218
GO:0007049	cell cycle	TAS		9682218
GO:0007067	mitosis	IEA		-
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	EXP		11285280
GO:0051301	cell division	IEA		-
GO:0051436	negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle	EXP		14593737
GO:0051437	positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	EXP		12791267
Cellular component	GO term	Evidence	Neuro keywords	PubMed ID
GO:0005819	spindle	TAS		7513050
GO:0005829	cytosol	EXP		11285280 \|11535616 \|11742988 \|12070128 \|15469984
GO:0005654	nucleoplasm	EXP		12791267 \|15469984

Section IV. Protein-protein interaction annotation

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ANAPC5	APC5	anaphase promoting complex subunit 5	Reconstituted Complex	BioGRID	12956947
ANAPC7	APC7	anaphase promoting complex subunit 7	Reconstituted Complex	BioGRID	12956947
APC	BTPS2 \| DP2 \| DP2.5 \| DP3 \| GS	adenomatous polyposis coli	-	HPRD	9637688 \|9811605
AURKA	AIK \| ARK1 \| AURA \| AURORA2 \| BTAK \| MGC34538 \| STK15 \| STK6 \| STK7	aurora kinase A	-	HPRD,BioGRID	10377410
BUB1	BUB1A \| BUB1L \| hBUB1	budding uninhibited by benzimidazoles 1 homolog (yeast)	Bub1 interacts with Cdc20.	BIND	15525512
BUB1B	BUB1beta \| BUBR1 \| Bub1A \| MAD3L \| SSK1 \| hBUBR1	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	BubR1 interacts with Cdc20.	BIND	15525512
BUB1B	BUB1beta \| BUBR1 \| Bub1A \| MAD3L \| SSK1 \| hBUBR1	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	-	HPRD,BioGRID	11030144 \|11274370 \|11535616 \|11907259
CCDC59	BR22 \| DKFZp686K1021 \| FLJ10294 \| HSPC128 \| TAP26	coiled-coil domain containing 59	Affinity Capture-MS	BioGRID	17353931
CCNA2	CCN1 \| CCNA	cyclin A2	-	HPRD,BioGRID	10679238
CCNB1	CCNB	cyclin B1	Cyclin B interacts with Cdc20.	BIND	15916961
CDC16	APC6	cell division cycle 16 homolog (S. cerevisiae)	-	HPRD,BioGRID	9628895 \|12196507
CDC27	APC3 \| CDC27Hs \| D0S1430E \| D17S978E \| HNUC	cell division cycle 27 homolog (S. cerevisiae)	Affinity Capture-Western Reconstituted Complex	BioGRID	9628895 \|9736712 \|9811605 \|12196507 \|12956947 \|14561775
CDC27	APC3 \| CDC27Hs \| D0S1430E \| D17S978E \| HNUC	cell division cycle 27 homolog (S. cerevisiae)	-	HPRD	9736712 \|12196507
FBXO5	EMI1 \| FBX5 \| Fbxo31	F-box protein 5	-	HPRD,BioGRID	11389834 \|11976684 \|11988738
HDAC1	DKFZp686H12203 \| GON-10 \| HD1 \| RPD3 \| RPD3L1	histone deacetylase 1	Affinity Capture-Western Co-purification	BioGRID	15388328
HDAC2	RPD3 \| YAF1	histone deacetylase 2	Affinity Capture-Western Co-purification	BioGRID	15388328
KRT31	HA1 \| Ha-1 \| KRTHA1 \| MGC138630 \| hHa1	keratin 31	Affinity Capture-MS	BioGRID	17353931
KRT32	HA2 \| HKA2 \| KRTHA2 \| hHa2	keratin 32	Affinity Capture-MS	BioGRID	17353931
KRT33A	HA3I \| Ha-3I \| KRTHA3A \| Krt1-3 \| hHa3-I	keratin 33A	Affinity Capture-MS	BioGRID	17353931
KRT85	HB5 \| Hb-5 \| KRTHB5 \| hHb5	keratin 85	Affinity Capture-MS	BioGRID	17353931
KRTAP19-5	KAP19.5	keratin associated protein 19-5	Affinity Capture-MS	BioGRID	17353931
KRTAP9-2	KAP9.2 \| KRTAP9.2 \| MGC130013	keratin associated protein 9-2	Affinity Capture-MS	BioGRID	17353931
KRTAP9-3	KAP9.3 \| KRTAP9.3	keratin associated protein 9-3	Affinity Capture-MS	BioGRID	17353931
MAD2L1	HSMAD2 \| MAD2	MAD2 mitotic arrest deficient-like 1 (yeast)	-	HPRD	9628895 \|9637688 \|9736712 \|10700282 \|11804586
MAD2L1	HSMAD2 \| MAD2	MAD2 mitotic arrest deficient-like 1 (yeast)	MAD2 interacts with p55CDC.	BIND	12456649
MAD2L1	HSMAD2 \| MAD2	MAD2 mitotic arrest deficient-like 1 (yeast)	MAD2L1 (Mad2) interacts with Cdc20.	BIND	15694304
MAD2L1	HSMAD2 \| MAD2	MAD2 mitotic arrest deficient-like 1 (yeast)	Mad2 interacts with Cdc20.	BIND	15525512
MAD2L1	HSMAD2 \| MAD2	MAD2 mitotic arrest deficient-like 1 (yeast)	Affinity Capture-Western Co-crystal Structure Reconstituted Complex Two-hybrid	BioGRID	9628895 \|9637688 \|9736712 \|10700282 \|11438673 \|11707408 \|12196507 \|14561775 \|14607335
MAD2L2	MAD2B \| REV7	MAD2 mitotic arrest deficient-like 2 (yeast)	Reconstituted Complex	BioGRID	11459826
PTTG1	EAP1 \| HPTTG \| MGC126883 \| MGC138276 \| PTTG \| TUTR1	pituitary tumor-transforming 1	-	HPRD	11553328
PTTG1	EAP1 \| HPTTG \| MGC126883 \| MGC138276 \| PTTG \| TUTR1	pituitary tumor-transforming 1	Securin interacts with Cdc20. This interaction was modelled on a demonstrated interaction between human Securin and Xenopus Cdc20.	BIND	15916961
SOSTDC1	CDA019 \| DKFZp564D206 \| ECTODIN \| USAG1	sclerostin domain containing 1	-	HPRD	15280373
SPATC1	MGC61633 \| SPATA15 \| SPERIOLIN	spermatogenesis and centriole associated 1	-	HPRD,BioGRID	15280373
YARS2	CGI-04 \| FLJ13995 \| TYRRS \| mt-TyrRS	tyrosyl-tRNA synthetase 2, mitochondrial	Affinity Capture-MS	BioGRID	17353931

Section V. Pathway annotation

Pathway name	Pathway size	# SZGR 2.0 genes in pathway	Info
KEGG CELL CYCLE	128	84	All SZGR 2.0 genes in this pathway
KEGG OOCYTE MEIOSIS	114	79	All SZGR 2.0 genes in this pathway
KEGG UBIQUITIN MEDIATED PROTEOLYSIS	138	98	All SZGR 2.0 genes in this pathway
PID PLK1 PATHWAY	46	25	All SZGR 2.0 genes in this pathway
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	24	12	All SZGR 2.0 genes in this pathway
REACTOME CELL CYCLE	421	253	All SZGR 2.0 genes in this pathway
REACTOME CELL CYCLE MITOTIC	325	185	All SZGR 2.0 genes in this pathway
REACTOME CELL CYCLE CHECKPOINTS	124	70	All SZGR 2.0 genes in this pathway
REACTOME REGULATION OF MITOTIC CELL CYCLE	85	46	All SZGR 2.0 genes in this pathway
REACTOME MITOTIC M M G1 PHASES	172	98	All SZGR 2.0 genes in this pathway
REACTOME DNA REPLICATION	192	110	All SZGR 2.0 genes in this pathway
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	72	38	All SZGR 2.0 genes in this pathway
REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	73	40	All SZGR 2.0 genes in this pathway
REACTOME MITOTIC PROMETAPHASE	87	51	All SZGR 2.0 genes in this pathway
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	26	10	All SZGR 2.0 genes in this pathway
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	51	32	All SZGR 2.0 genes in this pathway
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	22	9	All SZGR 2.0 genes in this pathway
REACTOME IMMUNE SYSTEM	933	616	All SZGR 2.0 genes in this pathway
REACTOME ADAPTIVE IMMUNE SYSTEM	539	350	All SZGR 2.0 genes in this pathway
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION	251	156	All SZGR 2.0 genes in this pathway
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	212	129	All SZGR 2.0 genes in this pathway
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	28	12	All SZGR 2.0 genes in this pathway
NAKAMURA CANCER MICROENVIRONMENT DN	46	29	All SZGR 2.0 genes in this pathway
SOTIRIOU BREAST CANCER GRADE 1 VS 3 UP	151	84	All SZGR 2.0 genes in this pathway
WILCOX RESPONSE TO PROGESTERONE UP	152	90	All SZGR 2.0 genes in this pathway
CASORELLI ACUTE PROMYELOCYTIC LEUKEMIA DN	663	425	All SZGR 2.0 genes in this pathway
CHARAFE BREAST CANCER LUMINAL VS MESENCHYMAL DN	460	312	All SZGR 2.0 genes in this pathway
HORIUCHI WTAP TARGETS DN	310	188	All SZGR 2.0 genes in this pathway
GAL LEUKEMIC STEM CELL DN	244	153	All SZGR 2.0 genes in this pathway
BASAKI YBX1 TARGETS UP	290	177	All SZGR 2.0 genes in this pathway
VECCHI GASTRIC CANCER EARLY UP	430	232	All SZGR 2.0 genes in this pathway
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS TURQUOISE DN	53	25	All SZGR 2.0 genes in this pathway
ODONNELL TFRC TARGETS DN	139	76	All SZGR 2.0 genes in this pathway
ODONNELL TARGETS OF MYC AND TFRC DN	45	25	All SZGR 2.0 genes in this pathway
KINSEY TARGETS OF EWSR1 FLII FUSION UP	1278	748	All SZGR 2.0 genes in this pathway
KIM WT1 TARGETS DN	459	276	All SZGR 2.0 genes in this pathway
ELVIDGE HYPOXIA DN	146	94	All SZGR 2.0 genes in this pathway
GRAHAM CML QUIESCENT VS NORMAL QUIESCENT UP	87	45	All SZGR 2.0 genes in this pathway
GRAHAM CML DIVIDING VS NORMAL QUIESCENT UP	181	101	All SZGR 2.0 genes in this pathway
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING DN	87	49	All SZGR 2.0 genes in this pathway
RODRIGUES THYROID CARCINOMA ANAPLASTIC UP	722	443	All SZGR 2.0 genes in this pathway
ENK UV RESPONSE EPIDERMIS UP	293	179	All SZGR 2.0 genes in this pathway
CONCANNON APOPTOSIS BY EPOXOMICIN DN	172	112	All SZGR 2.0 genes in this pathway
BERENJENO TRANSFORMED BY RHOA UP	536	340	All SZGR 2.0 genes in this pathway
TANG SENESCENCE TP53 TARGETS DN	57	33	All SZGR 2.0 genes in this pathway
JOHANSSON GLIOMAGENESIS BY PDGFB UP	58	44	All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL BREAST 6 7WK DN	79	54	All SZGR 2.0 genes in this pathway
KONG E2F3 TARGETS	97	58	All SZGR 2.0 genes in this pathway
FARMER BREAST CANCER APOCRINE VS BASAL	330	217	All SZGR 2.0 genes in this pathway
FARMER BREAST CANCER BASAL VS LULMINAL	330	215	All SZGR 2.0 genes in this pathway
ROSTY CERVICAL CANCER PROLIFERATION CLUSTER	140	73	All SZGR 2.0 genes in this pathway
WAESCH ANAPHASE PROMOTING COMPLEX	12	7	All SZGR 2.0 genes in this pathway
PATIL LIVER CANCER	747	453	All SZGR 2.0 genes in this pathway
KORKOLA TERATOMA	39	25	All SZGR 2.0 genes in this pathway
MOHANKUMAR TLX1 TARGETS UP	414	287	All SZGR 2.0 genes in this pathway
SHETH LIVER CANCER VS TXNIP LOSS PAM1	229	137	All SZGR 2.0 genes in this pathway
SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN UP	479	299	All SZGR 2.0 genes in this pathway
PUJANA XPRSS INT NETWORK	168	103	All SZGR 2.0 genes in this pathway
PUJANA BRCA1 PCC NETWORK	1652	1023	All SZGR 2.0 genes in this pathway
PUJANA BRCA2 PCC NETWORK	423	265	All SZGR 2.0 genes in this pathway
PUJANA ATM PCC NETWORK	1442	892	All SZGR 2.0 genes in this pathway
PUJANA CHEK2 PCC NETWORK	779	480	All SZGR 2.0 genes in this pathway
PUJANA BRCA CENTERED NETWORK	117	72	All SZGR 2.0 genes in this pathway
WILLIAMS ESR1 TARGETS UP	26	16	All SZGR 2.0 genes in this pathway
NUYTTEN EZH2 TARGETS DN	1024	594	All SZGR 2.0 genes in this pathway
SCIAN CELL CYCLE TARGETS OF TP53 AND TP73 DN	22	14	All SZGR 2.0 genes in this pathway
BENPORATH ES 1	379	235	All SZGR 2.0 genes in this pathway
BENPORATH CYCLING GENES	648	385	All SZGR 2.0 genes in this pathway
GEORGES TARGETS OF MIR192 AND MIR215	893	528	All SZGR 2.0 genes in this pathway
MORI PRE BI LYMPHOCYTE UP	80	54	All SZGR 2.0 genes in this pathway
MORI LARGE PRE BII LYMPHOCYTE UP	86	49	All SZGR 2.0 genes in this pathway
MORI IMMATURE B LYMPHOCYTE DN	90	55	All SZGR 2.0 genes in this pathway
SHEPARD BMYB MORPHOLINO DN	200	112	All SZGR 2.0 genes in this pathway
SHEPARD BMYB TARGETS	74	41	All SZGR 2.0 genes in this pathway
SHEPARD CRUSH AND BURN MUTANT DN	185	111	All SZGR 2.0 genes in this pathway
TARTE PLASMA CELL VS PLASMABLAST DN	309	206	All SZGR 2.0 genes in this pathway
LE EGR2 TARGETS UP	108	75	All SZGR 2.0 genes in this pathway
BYSTRYKH HEMATOPOIESIS STEM CELL QTL TRANS	882	572	All SZGR 2.0 genes in this pathway
LI WILMS TUMOR VS FETAL KIDNEY 1 DN	163	115	All SZGR 2.0 genes in this pathway
ALCALAY AML BY NPM1 LOCALIZATION DN	184	132	All SZGR 2.0 genes in this pathway
HADDAD T LYMPHOCYTE AND NK PROGENITOR DN	63	41	All SZGR 2.0 genes in this pathway
LEE AGING NEOCORTEX DN	80	49	All SZGR 2.0 genes in this pathway
WEIGEL OXIDATIVE STRESS BY HNE AND H2O2	39	29	All SZGR 2.0 genes in this pathway
PAL PRMT5 TARGETS UP	203	135	All SZGR 2.0 genes in this pathway
KANG DOXORUBICIN RESISTANCE UP	54	33	All SZGR 2.0 genes in this pathway
RHODES UNDIFFERENTIATED CANCER	69	44	All SZGR 2.0 genes in this pathway
BURTON ADIPOGENESIS 3	101	64	All SZGR 2.0 genes in this pathway
DELLA RESPONSE TO TSA AND BUTYRATE	21	17	All SZGR 2.0 genes in this pathway
BURTON ADIPOGENESIS PEAK AT 24HR	43	30	All SZGR 2.0 genes in this pathway
LY AGING OLD DN	56	35	All SZGR 2.0 genes in this pathway
SESTO RESPONSE TO UV C7	68	44	All SZGR 2.0 genes in this pathway
SIMBULAN PARP1 TARGETS DN	17	10	All SZGR 2.0 genes in this pathway
LY AGING MIDDLE DN	16	10	All SZGR 2.0 genes in this pathway
HU GENOTOXIC DAMAGE 4HR	35	28	All SZGR 2.0 genes in this pathway
GAVIN FOXP3 TARGETS CLUSTER P6	91	44	All SZGR 2.0 genes in this pathway
MARSON BOUND BY E2F4 UNSTIMULATED	728	415	All SZGR 2.0 genes in this pathway
HELLER SILENCED BY METHYLATION UP	282	183	All SZGR 2.0 genes in this pathway
HELLER HDAC TARGETS UP	317	208	All SZGR 2.0 genes in this pathway
WONG PROTEASOME GENE MODULE	49	35	All SZGR 2.0 genes in this pathway
ACEVEDO LIVER CANCER UP	973	570	All SZGR 2.0 genes in this pathway
ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE UP	863	514	All SZGR 2.0 genes in this pathway
SMID BREAST CANCER LUMINAL A DN	18	7	All SZGR 2.0 genes in this pathway
SMID BREAST CANCER BASAL UP	648	398	All SZGR 2.0 genes in this pathway
KUMAMOTO RESPONSE TO NUTLIN 3A DN	10	5	All SZGR 2.0 genes in this pathway
ZHENG GLIOBLASTOMA PLASTICITY UP	250	168	All SZGR 2.0 genes in this pathway
GRADE COLON CANCER UP	871	505	All SZGR 2.0 genes in this pathway
BHATI G2M ARREST BY 2METHOXYESTRADIOL UP	125	68	All SZGR 2.0 genes in this pathway
BLUM RESPONSE TO SALIRASIB DN	342	220	All SZGR 2.0 genes in this pathway
FRASOR RESPONSE TO SERM OR FULVESTRANT DN	50	29	All SZGR 2.0 genes in this pathway
GOLDRATH ANTIGEN RESPONSE	346	192	All SZGR 2.0 genes in this pathway
VANTVEER BREAST CANCER ESR1 DN	240	153	All SZGR 2.0 genes in this pathway
HOFFMANN LARGE TO SMALL PRE BII LYMPHOCYTE UP	163	102	All SZGR 2.0 genes in this pathway
HOFFMANN SMALL PRE BII TO IMMATURE B LYMPHOCYTE DN	50	33	All SZGR 2.0 genes in this pathway
SHEDDEN LUNG CANCER POOR SURVIVAL A6	456	285	All SZGR 2.0 genes in this pathway
COLINA TARGETS OF 4EBP1 AND 4EBP2	356	214	All SZGR 2.0 genes in this pathway
ZHAN EARLY DIFFERENTIATION GENES DN	42	29	All SZGR 2.0 genes in this pathway
MILI PSEUDOPODIA HAPTOTAXIS DN	668	419	All SZGR 2.0 genes in this pathway
CROONQUIST IL6 DEPRIVATION DN	98	69	All SZGR 2.0 genes in this pathway
CROONQUIST NRAS SIGNALING DN	72	47	All SZGR 2.0 genes in this pathway
CROONQUIST NRAS VS STROMAL STIMULATION DN	99	65	All SZGR 2.0 genes in this pathway
ISHIDA E2F TARGETS	53	27	All SZGR 2.0 genes in this pathway
POOLA INVASIVE BREAST CANCER UP	288	168	All SZGR 2.0 genes in this pathway
CHIANG LIVER CANCER SUBCLASS PROLIFERATION UP	178	108	All SZGR 2.0 genes in this pathway
PUJANA BREAST CANCER WITH BRCA1 MUTATED UP	56	27	All SZGR 2.0 genes in this pathway
KOBAYASHI EGFR SIGNALING 24HR DN	251	151	All SZGR 2.0 genes in this pathway
HOSHIDA LIVER CANCER SUBCLASS S1	237	159	All SZGR 2.0 genes in this pathway
CAIRO HEPATOBLASTOMA CLASSES UP	605	377	All SZGR 2.0 genes in this pathway
KYNG WERNER SYNDROM AND NORMAL AGING DN	225	124	All SZGR 2.0 genes in this pathway
WONG EMBRYONIC STEM CELL CORE	335	193	All SZGR 2.0 genes in this pathway
NAKAYAMA SOFT TISSUE TUMORS PCA2 UP	87	50	All SZGR 2.0 genes in this pathway
WHITFIELD CELL CYCLE LITERATURE	44	25	All SZGR 2.0 genes in this pathway
WHITFIELD CELL CYCLE G2 M	216	124	All SZGR 2.0 genes in this pathway
CHICAS RB1 TARGETS GROWING	243	155	All SZGR 2.0 genes in this pathway
JOHNSTONE PARVB TARGETS 3 DN	918	550	All SZGR 2.0 genes in this pathway
FEVR CTNNB1 TARGETS DN	553	343	All SZGR 2.0 genes in this pathway
GOBERT OLIGODENDROCYTE DIFFERENTIATION UP	570	339	All SZGR 2.0 genes in this pathway
SERVITJA LIVER HNF1A TARGETS UP	135	96	All SZGR 2.0 genes in this pathway
YANG BCL3 TARGETS UP	364	236	All SZGR 2.0 genes in this pathway
LE NEURONAL DIFFERENTIATION DN	19	16	All SZGR 2.0 genes in this pathway
FOSTER KDM1A TARGETS DN	211	119	All SZGR 2.0 genes in this pathway
ACEVEDO FGFR1 TARGETS IN PROSTATE CANCER MODEL UP	289	184	All SZGR 2.0 genes in this pathway
SMIRNOV RESPONSE TO IR 6HR DN	114	69	All SZGR 2.0 genes in this pathway
ZHOU CELL CYCLE GENES IN IR RESPONSE 24HR	128	73	All SZGR 2.0 genes in this pathway

Gene Page: CDC20