Found 616 literature records

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Entrez ID	Description
56849	"TCEAL7 is a cell death regulatory protein that is frequently inactivated in ovarian cancers, and may function as a tumor suppressor."
51147	Frequent deletion and decreased mRNA expression of ING4 suggested it as a class two tumor suppressor gene and may play an important role in head and neck cancer.
4763	NF1 tumor suppressor critically regulates TSC2 and the mTOR pathway.
112464	"hSRBC is a candidate tumor suppressor gene involved in lung cancer pathogenesis, where expression is frequently inactivated by methylation and other mechanisms"
6117	Rpa1 functions in DNA metabolism are essential for the maintenance of chromosomal stability and tumor suppression.
1029	Alterations of tumor suppressor gene p16INK4a in pancreatic ductal carcinoma.
4763	"NF1 tumor suppressor gene is a direct transcriptional target of RUNX1 and the t(8;21) fusion protein, suggesting that suppression of NF1 expression contributes to the molecular pathogenesis of acute myeloid leukemia ."
5728	Negative regulation of CXCR4-mediated chemotaxis by the lipid phosphatase activity of tumor suppressor PTEN.
6422	"SFRP 1 gene is frequently downregulated by promoter hypermethylation and suppresses tumor growth activity of lung cancer cells, which suggests that SFRP 1 is a candidate tumor suppressor gene for lung cancer"
9770	RASSF2 is a novel tumor suppressor gene that regulates Ras signaling and plays a pivotal role in the early stages of colorectal tumorigenesis.
4763	A conditional allele of the NF1 tumor suppressor that negatively regulates Ras signaling together with inactivation of p53 induce malignant astrocytoma.
7157	Inactivation of p53 and a conditional allele of the NF1 tumor suppressor that negatively regulates Ras signaling induce malignant astrocytoma.
79577	Identification of a functional bipartite nuclear localization signal in the tumor suppressor parafibromin.
1540	The tumor suppressor familial cylindromatosis gene (CYLD) was found to be a direct target of BAF57 as determined by chromatin immunoprecipitation analysis. (CYLD)
51741	Characterization of the tumor suppressor gene WWOX in primary human oral squamous cell carcinomas.
8854	The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer.
10912	Results show that GADD45G can act as a functional new-age tumor suppressor but being frequently inactivated epigenetically in multiple tumors.
57575	"Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation."
199731	"Cell adhesion and prostate tumor-suppressor activity of TSLL2/IGSF4C, an immunoglobulin superfamily molecule homologous to TSLC1/IGSF4"
10481	Epigenetic inactivation of the candidate tumor suppressor gene HOXB13 in human renal cell carcinoma.
135138	"candidate tumor suppressor genes PARK2 and PACRG are epigenetically regulated in human leukemia, suggesting that abnormal methylation and regulation of PARK2 and PACRG may play a role in the pathogenesis and development of this hematological neoplasm"
5071	"candidate tumor suppressor genes PARK2 and PACRG are epigenetically regulated in human leukemia, suggesting that abnormal methylation and regulation of PARK2 and PACRG may play a role in the pathogenesis and development of this hematological neoplasm"
51741	Activated tyrosine kinase Ack1 promotes prostate tumorigenesis by tyrosine phosphorylation of tumor suppressor Wwox at Tyr-287. It leads to polyubiquitination and degradation.
79791	"FBXO31 is the chromosome 16q24.3 senescence gene, a candidate breast tumor suppressor, and a component of an SCF complex."
5728	The tumor suppressor PTEN is necessary for human Sprouty 2-mediated inhibition of cell proliferation.
7249	Modulation of cell migration and invasiveness by tumor suppressor TSC2 in lymphangioleiomyomatosis.
23705	"Human lung mast cells adhere to human airway smooth muscle, in part, via tumor suppressor in lung cancer-1."
7157	"BTG2 expression was found to be significantly reduced in a large proportion of human kidney and breast carcinomas, suggesting that BTG2 is a tumor suppressor that links p53 and Rb pathways in human tumorigenesis."
7832	"BTG2 expression was found to be significantly reduced in a large proportion of human kidney and breast carcinomas, suggesting that BTG2 is a tumor suppressor that links p53 and Rb pathways in human tumorigenesis."
1676	apoptotic DNA fragmentation factor is required for the maintenance of genetic stability and may play a role in tumor suppression
3621	"Alterations in novel candidate tumor suppressor genes, ING1 and ING2 in human lung cancer."
3622	"Alterations in novel candidate tumor suppressor genes, ING1 and ING2 in human lung cancer."
8651	Mutations of the tumor suppressor gene SOCS-1 in classical Hodgkin lymphoma are frequent and associated with nuclear phospho-STAT5 accumulation
1050	Epigenetic modulation of tumor suppressor CCAAT/enhancer binding protein alpha activity in lung cancer.
5915	Down-regulation of the tumor suppressor gene retinoic acid receptor beta2 through the phosphoinositide 3-kinase/Akt signaling pathway.
1028	Compensation by tumor suppressor genes during retinal development in mice and humans.
5925	Compensation by tumor suppressor genes during retinal development in mice and humans.
5933	Compensation by tumor suppressor genes during retinal development in mice and humans.
5934	Compensation by tumor suppressor genes during retinal development in mice and humans.
6422	Compensation by tumor suppressor genes during retinal development in mice and humans.
10904	might be a potential tumor suppressor gene in cervical carcinoma.
5728	Loss of heterozygosity is an independent prognostic factor and PTEN is a candidate as a haploinsufficient tumor suppressor in gastric cancers.
9940	Candidate tumor-suppressor gene DLEC1 is frequently downregulated by promoter hypermethylation and histone hypoacetylation in human epithelial ovarian cancer.
1029	Tumor suppressor p16INK4A regulates polycomb-mediated DNA hypermethylation in human mammary epithelial cells.
56999	"Identification of a tumor suppressive critical region mapping to 3p14.2 in esophageal squamous cell carcinoma and studies of a candidate tumor suppressor gene, ADAMTS9."
84707	Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma.
1029	Induction of the tumor-suppressor p16(INK4a) within regenerative epithelial crypts in ulcerative colitis.
7078	"Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer. we first demonstrated the functional consequence of methylation of several recently identified tumor suppressor genes, including those for tissue inhibitor of metalloproteinase-3 (TIMP3), SLC5A8, death-associated protein kinase (DAPK) and retinoic acid receptor beta2 (RARbeta2). "
160728	Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer.
1612	Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer.

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