Found 476 literature records

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Entrez ID	Description
3169	These results suggest that FOXA1 functions as a tumor suppressor through modulation of proliferation and migration of endometrial cancer cells.
406907	"Identification and validation of three miRNAs (miR-124, miR-147 and miR-193a-3p) as novel tumor suppressors that co-target EGFR-driven cell-cycle network proteins and inhibit cell-cycle progression and proliferation in breast cancer."
406939	"Identification and validation of three miRNAs (miR-124, miR-147 and miR-193a-3p) as novel tumor suppressors that co-target EGFR-driven cell-cycle network proteins and inhibit cell-cycle progression and proliferation in breast cancer."
406968	"Identification and validation of three miRNAs (miR-124, miR-147 and miR-193a-3p) as novel tumor suppressors that co-target EGFR-driven cell-cycle network proteins and inhibit cell-cycle progression and proliferation in breast cancer."
207	"melatonin inhibits cell proliferation and induces apoptosis in MDA-MB-361 breast cancer cells in vitro by simultaneously suppressing the COX-2/PGE2, p300/NF-kappaB, and PI3K/Akt/signaling and activating the Apaf-1/caspase-dependent apoptotic pathway."
3977	"findings show that LIFR is a key novel tumor suppressor, whose deregulation may drive the transformation of a significant proportion of human breast cancers"
3428	this novel DNA-binding property of IFI16 protein to scDNA and cruciform structures may play critical roles in its tumor suppressor function.
5915	nucleolin plays a coregulatory role in transcriptional regulation of the tumor suppressor RARB2 by COUP-TFII
5037	"Taken together,these data indicate that miR-224 play an important role in metastasis of human breast cancer cells to the bone by directly suppressing the RKIP tumor suppressor."
407040	"ZEB1 controls the expression of numerous oncogenic and tumor-suppressive miRs, including miR-34a"
3091	HIF1alpha acts as a tumor promoter in stromal cells but as a tumor suppressor in cancer cells.
406940	"miR-148a and miR-152 act as tumor suppressors by targeting IGF-IR and IRS1, and that restoration of miR-148a/152 expression may provide a strategy for therapeutic application to treat BC patients."
406943	"miR-148a and miR-152 act as tumor suppressors by targeting IGF-IR and IRS1, and that restoration of miR-148a/152 expression may provide a strategy for therapeutic application to treat BC patients."
5100	study demonstrates the epigenetic inactivation of PCDH8 by promoter methylation and its tumor suppressor function in gastric cancer
407040	MicroRNA-34 suppresses breast cancer invasion and metastasis by directly targeting Fra-1.
7158	53BP1 functions as a tumor suppressor in breast cancer via the inhibition of NF-kappaB through miR-146a.
1036	CDO1 as a novel tumor suppressor gene and a potentially valuable molecular marker for human cancer
406906	Results demonstrate that miR-122 functions as a tumor suppressor and plays an important role in inhibiting the tumorigenesis through targeting IGF1.
9901	"conclude that srGAP3 has tumor suppressor-like activity in HMECs, likely through its activity as a negative regulator of Rac1"
388	"In cancer cells in vitro or in vivo, RhoB functions as a tumor suppressor that restricts EGF receptor (EGFR) cell surface occupancy as well as Akt signaling"
79577	Oncogenic microRNA-155 down-regulates tumor suppressor CDC73 and promotes oral squamous cell carcinoma cell proliferation
2099	The findings reveal a tumor suppressive role of hsa-miR-196a2 through regulation of TP63 by ERalpha and/or ERK2 signaling.
406973	The findings reveal a tumor suppressive role of hsa-miR-196a2 through regulation of TP63 by ERalpha and/or ERK2 signaling.
406929	miR-138 acts as a tumor suppressor and may prevent metastasis.
6498	These data strongly suggest that SnoN can function as a tumor suppressor at early stages of tumorigenesis in human cancer tissues.
79648	"in addition to its role in brain development, MCPH1 also functions as a tumor suppressor gene and is regulated by miR-27a"
4486	"the function of RON in tumors may be multidimensional, not just as a tumor suppressor or oncogene."
140690	"CTCF and BORIS suppressed breast cancer growth; findings provide further evidence that CTCF behaves as a tumor suppressor, and show BORIS has a similar growth inhibitory effect in vitro and in vivo"
8405	"SPOP plays a critical tumor suppressor role in prostate cancer cells, promoting the turnover of SRC-3 protein and suppressing androgen receptor transcriptional activity."
10637	Beta-catenin can recruit the H3K4me2/1 demethylase LSD1 to regulate the expression of the tumor suppressor Lefty1 in mouse embryonic stem cells.
4854	Results reveal a novel function of Notch3 in senescence regulation and tumor suppression.
3880	KRT19 is a potential tumor suppressor that negatively regulates Akt signaling through modulation of Egr1 nuclear localization.
8864	findings clearly demonstrate the tumor suppression function of PER2 and elucidate a pathway by which hypoxia promotes EMT via degradation of PER2
55223	results provide compelling evidence that DEAR1 is a critical tumor suppressor involved in multiple human cancers and provide a novel paradigm for regulation of TGF-beta-induced EMT through DEAR1's regulation of SMAD3 protein levels
414899	BRCC2 functions as a novel tumor suppressor in breast cancer and may be a potential therapeutic target for breast cancer management.
9462	"The RasGAP gene, RASAL2, is a tumor and metastasis suppressor"
406911	"miR-125b acts as a tumor suppressor in breast tumorigenesis via its novel direct targets ENPEP, CK2-alpha, CCNJ, and MEGF9."
90993	CREB3L1 plays an important role in suppressing tumorigenesis and that loss of expression is required for the development of a metastatic phenotype.
406988	miR-205 is a tumor suppressor in human breast cancer by post-transcriptional inhibition of HER3 expression.
4920	ROR2 is an epigenetically inactivated tumor suppressor gene that antagonizes both beta-catenin and AKT signaling in multiple various carcinomas.
57758	Tumor suppressor SCUBE2 inhibits breast-cancer cell migration and invasion through the reversal of epithelial-mesenchymal transition.
406989	"These observations support hsa-miR-206 as a tumor suppressor in melanoma and identify Cyclin C, Cyclin D1, and CDK4 as miR-206 targets."
406907	study demonstrated that miR-124 might be a tumor suppressor in breast cancer via the regulation of FLOT1
338442	GPR109A is a tumor suppressor in mammary gland.
10771	identification of ZMYND11 as an H3.3-specific reader of H3K36me3 that links the histone-variant-mediated transcription elongation control to tumor suppression
27022	Our results indicate FOXD3 exhibits tumor suppressive activity and may be useful for breast therapy.
79026	Ahnak mediates a negative regulation of cell growth and acts as novel tumor suppressor through potentiation of TGFB signaling.
22925	This review compiles recent data demonstrating an unexpected tumor suppressive role of PLA2R1 and outlines the future work needed to improve our knowledge of the functions of this gene in cancer.[review]
55544	Suggest that RNPC1 had a potential function to play a tumor-suppressor role which may be a potential marker in the therapeutic and prognostic of breast cancer.
9077	The data indicate that JMJD2A could promote breast cancer progression through transcriptional repression of the tumor suppressor ARHI.

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