Found 155 literature records

Page :1 2 3 4

Entrez ID	Description
2134	"Recently, the EXTL1 gene, a member of the EXT tumor suppressor gene family, has been mapped to 1p36, a chromosome region which is frequently implicated in a wide variety of malignancies, including breast carcinoma, colorectal cancer and neuroblastoma. "
324	Genomic rearrangements of the APC tumor-suppressor gene in familial adenomatous polyposis.
324	Apical membrane localization of the adenomatous polyposis coli tumor suppressor protein and subcellular distribution of the beta-catenin destruction complex in polarized epithelial cells.
1630	"Interaction of Myc-associated zinc finger protein with DCC, the product of a tumor-suppressor gene, during the neural differentiation of P19 EC cells."
1029	Evaluation of alterations in the tumor suppressor genes INK4A and INK4B in human bladder tumors.
1030	Evaluation of alterations in the tumor suppressor genes INK4A and INK4B in human bladder tumors.
9353	SLIT2 is an excellent candidate tumor suppressor gene for colorectal cancer.
6392	SDHD may have a role in colorectal and gastric cancers as a distinct type of tumor suppressor
9314	KLF4 is a tumor suppressor in colorectal cancer.
1316	Kruppel-like factor 6 (KLF6) is a tumor-suppressor gene frequently inactivated in colorectal cancer.
4089	Status of the DPC4 tumor suppressor gene in sporadic colon adenocarcinoma of Croatian patients: identification of a novel somatic mutation.
8651	These findings suggested that SOCS-1 may act as a tumor suppressor in at least some colorectal cancers and that SOCS-1 methylation may be a particular phenomenon related to a nearly onset of colorectal cancer.
1316	Transcriptional activation of the insulin-like growth factor I receptor gene by the Kruppel-like factor 6 (KLF6) tumor suppressor protein.
5728	"We found that indomethacin and NS-398 treatment significantly upregulated expression of the tumor suppressor gene, PTEN."
3400	ID4 gene is a potential tumor suppressor gene for which methylation status may play an important role in the CRC progression
3678	integrin alpha5/beta1 exerts its tumor suppressor-like activity in colon cancer cells by inhibiting HER-2 signaling
3688	integrin alpha5/beta1 exerts its tumor suppressor-like activity in colon cancer cells by inhibiting HER-2 signaling
1029	Methylation and expression of p16INK4 tumor suppressor gene in primary colorectal cancer tissues.
4436	"Tumor suppressor gene, hMSH2, may play an important role as a putative coactivator in ER alpha dependent gene expression."
9770	RASSF2 is a novel tumor suppressor gene that regulates Ras signaling and plays a pivotal role in the early stages of colorectal tumorigenesis.
2932	Our findings demonstrate an unrecognized role of GSK3beta in tumor cell survival and proliferation other than its predicted role as a tumor suppressor.
1316	Absence of mutation in the putative tumor-suppressor gene KLF6 in colorectal cancers.
324	The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.
4221	The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.
324	The adenomatous polyposis coli tumor suppressor gene regulates expression of cyclooxygenase-2 by a mechanism that involves retinoic acid.
1316	KLF6 gene may be one of the candidate tumor suppressor genes in colorectal cancers and that genetic alteration of the KLF6 gene might play a role in the development of colorectal carcinomas.
1630	Automated quantitative analysis of DCC tumor suppressor protein in ovarian cancer tissue microarray shows association with beta-catenin levels and outcome in patients with epithelial ovarian cancer.
2050	"Study provides evidence showing that promoter methylation regulates EPHB4 transcription and that EPHB4 can regulate the long-term clonogenic potential of colorectal tumor cells, revealing EPHB4 as a potential tumor suppressor gene in colorectal cancer."
10395	Expression profile of the tumor suppressor genes DLC-1 and DLC-2 in solid tumors.
90627	Expression profile of the tumor suppressor genes DLC-1 and DLC-2 in solid tumors.
1630	Deleted in colorectal cancer is a putative conditional tumor-suppressor gene inactivated by promoter hypermethylation in head and neck squamous cell carcinoma.
3486	"Results showed that IGFBP-3 methylation played an important role in the silencing of its expression, suggesting that IGFBP-3 may act as a tumor suppressor gene in several human cancers examined."
55743	"CHFR might act as a tumor suppressor in at least some colorectal cancers and that CHFR methylation might, therefore, be a particular phenomenon of early colorectal cancer"
324	Caspase cleavage of the APC tumor suppressor and release of an amino-terminal domain is required for the transcription-independent function of APC in apoptosis.
27250	Tumor suppressor Pdcd4 inhibits invasion/intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factors.
27113	the binding of nuclear p53 to the specific sites within the PUMA promoter is essential for its ability to induce apoptosis and is likely to be required for its tumor suppressive capacity
139285	"findings show that WTX, a protein encoded by a gene mutated in Wilms tumors, forms a complex with beta-catenin, AXIN1, beta-TrCP2 and APC; data provide a possible mechanistic explanation for the tumor suppressor activity of WTX"
324	Familial adenomas polyp is caused by mutations in the APC tumor suppressor gene.
7157	p53 and Msh6 are functionally interrelated and these tumor suppressors act together to accelerate tumorigenesis.
9447	The putative tumor suppressor AIM2 is frequently affected by different genetic alterations in microsatellite unstable colon cancers.
1687	DFNA5 is a novel tumor suppressor gene in CRC and a valuable molecular marker for human cancer
324	The armadillo repeat domain of the APC tumor suppressor protein interacts with Striatin family members.
407041	"miR-34b/c and BTG4 are novel tumor suppressors in colorectal cancer (CRC) and that the miR-34b/c CpG island, which bidirectionally regulates miR-34b/c and BTG4, is a frequent target of epigenetic silencing in CRC"
407042	"miR-34b/c and BTG4 are novel tumor suppressors in colorectal cancer (CRC) and that the miR-34b/c CpG island, which bidirectionally regulates miR-34b/c and BTG4, is a frequent target of epigenetic silencing in CRC"
54766	"miR-34b/c and BTG4 are novel tumor suppressors in colorectal cancer (CRC) and that the miR-34b/c CpG island, which bidirectionally regulates miR-34b/c and BTG4, is a frequent target of epigenetic silencing in CRC"
64682	Cdh1 may function as a component in tumor suppression via proteolysis of Skp2 in colorectal tumorigenesis and may serve as a prognostic marker in colon cancer patients.
2137	Exostoses like-3 (EXTL3) is a putative tumour suppressor gene.
1634	Data demonstrate that decorin acts as a tumor suppressor gene and plays an important role in the maintenance of cell maturation and therefore homeostasis in the intestinal tract.
4163	"MCC is a nuclear, beta-catenin-interacting protein that can act as a potential tumor suppressor in the serrated colorectal cancer pathway by inhibiting Wnt/beta-catenin signal transduction."
2048	A tumor suppressor role for EPHB2 in rare colorectal cancer cases; rare germline EPHB2 variants may contribute to a small fraction of hereditary colorectal cancer.

---