KinaseMD: Kinase mutations and drug responses

• All kinase in CDK
• All substructure loci
• Gatekeeper loci
• G-loop loci
• A-loop loci
• αC-helix loci

Uniprot ID	Gene symbol	Gatekeeper location	G loop location	A loop location	αC-Helix location
P06493	CDK1	80	145...168	10...19	40...42
Q15131	CDK10	117	180...191, 193...203	[N/A]	[N/A]
Q9UQ88	CDK11A	504	567...578, 580...590	[N/A]	[N/A]
Q9NYV4	CDK12	813	876...888, 890...900	733...739	769...778
Q14004	CDK13	791	854...866, 868...878	711...717	747...758
O94921	CDK14	210	273...296	[N/A]	[N/A]
Q00536	CDK16	240	303...326	171...177	206...217
P24941	CDK2	80	144...167	10...16	46...54
Q8IZL9	CDK20	81	144...155, 160...168	[N/A]	[N/A]
Q00526	CDK3	80	144...167	[N/A]	[N/A]
P11802	CDK4	93	[N/A]	[N/A]	51...63
Q00535	CDK5	80	143...166	10...16	46...55
Q00534	CDK6	98	162...184	20...27	58...70
P50613	CDK7	91	154...165, 167...177	19...26	58...68
P49336	CDK8	97	172...198	[N/A]	61...72
P50750	CDK9	103	166...180, 183...193	[N/A]	61...72