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Dataset Description
  • Dataset Name: HuGE Navigator
  • Species: Human
  • Method: Literature data mining
  • No. of Genes: 188
  • Phenotype: Alcoholism
  • Publication: Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
  • Dataset Summary: HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.

    Gene list of this dataset (188 genes)
    Page: 1 2 3 4 list all   
    GeneIDSymbolNameGenetic locationPhenotypeNo. of Support Publications
    5243ABCB1ATP-binding cassette, sub-family B (MDR/TAP), member 17q21.1Alcoholism2
    1636ACEangiotensin I converting enzyme (peptidyl-dipeptidase A) 117q23.3Alcoholism4
    57001ACN9ACN9 homolog (S. cerevisiae)7q21.3Alcoholism1
    4185ADAM11ADAM metallopeptidase domain 1117q21.3Alcoholism1
    118ADD1adducin 1 (alpha)4p16.3Alcoholism1
    124ADH1Aalcohol dehydrogenase 1A (class I), alpha polypeptide4q21-q23Alcoholism3
    125ADH1Balcohol dehydrogenase 1B (class I), beta polypeptide4q21-q23Alcoholism60
    126ADH1Calcohol dehydrogenase 1C (class I), gamma polypeptide4q21-q23Alcoholism34
    127ADH4alcohol dehydrogenase 4 (class II), pi polypeptide4q21-q24|4q22Alcoholism4
    128ADH5alcohol dehydrogenase 5 (class III), chi polypeptide4q21-q25Alcoholism2
    130ADH6alcohol dehydrogenase 6 (class V)4q23Alcoholism1
    131ADH7alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide4q23-q24Alcoholism2
    135ADORA2Aadenosine A2a receptor22q11.23Alcoholism1
    150ADRA2Aadrenergic, alpha-2A-, receptor10q24-q26Alcoholism2
    151ADRA2Badrenergic, alpha-2B-, receptor2p13-q13Alcoholism1
    152ADRA2Cadrenergic, alpha-2C-, receptor4p16Alcoholism2
    153ADRB1adrenergic, beta-1-, receptor10q24-q26Alcoholism1
    155ADRB3adrenergic, beta-3-, receptor8p12-p11.2Alcoholism1
    183AGTangiotensinogen (serpin peptidase inhibitor, clade A, member 8)1q42-q43Alcoholism1
    185AGTR1angiotensin II receptor, type 13q21-q25Alcoholism1
    213ALBalbumin4q11-q13Alcoholism1
    216ALDH1A1aldehyde dehydrogenase 1 family, member A19q21.13Alcoholism4
    219ALDH1B1aldehyde dehydrogenase 1 family, member B19p11.1Alcoholism1
    217ALDH2aldehyde dehydrogenase 2 family (mitochondrial)12q24.2Alcoholism72
    255239ANKK1ankyrin repeat and kinase domain containing 111q23.1Alcoholism3
    290ANPEPalanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150)15q25-q26Alcoholism1
    348APOEapolipoprotein E19q13.2Alcoholism13
    367ARandrogen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)Xq11.2-q12Alcoholism2
    410ARSAarylsulfatase A22q13.31-qter|22q13.33Alcoholism2
    627BDNFbrain-derived neurotrophic factor11p13Alcoholism5
    9607CARTPTCART prepropeptide5q13.2Alcoholism1
    847CATcatalase11p13Alcoholism1
    885CCKcholecystokinin3p22-p21.3Alcoholism3
    886CCKARcholecystokinin A receptor4p15.1-p15.2Alcoholism3
    887CCKBRcholecystokinin B receptor11p15.4Alcoholism2
    929CD14CD14 molecule5q22-q32|5q31.1Alcoholism2
    920CD4CD4 molecule12pter-p12Alcoholism1
    925CD8ACD8a molecule2p12Alcoholism1
    1080CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)7q31.2Alcoholism1
    1129CHRM2cholinergic receptor, muscarinic 27q31-q35Alcoholism4
    1136CHRNA3cholinergic receptor, nicotinic, alpha 315q24Alcoholism1
    1137CHRNA4cholinergic receptor, nicotinic, alpha 420q13.2-q13.3Alcoholism2
    1138CHRNA5cholinergic receptor, nicotinic, alpha 515q24Alcoholism1
    8973CHRNA6cholinergic receptor, nicotinic, alpha 68p11.21Alcoholism1
    1141CHRNB2cholinergic receptor, nicotinic, beta 2 (neuronal)1q21.3Alcoholism1
    1142CHRNB3cholinergic receptor, nicotinic, beta 38p11.2Alcoholism1
    1143CHRNB4cholinergic receptor, nicotinic, beta 415q24Alcoholism1
    1268CNR1cannabinoid receptor 1 (brain)6q14-q15Alcoholism7
    1312COMTcatechol-O-methyltransferase22q11.21-q11.23|22q11.21Alcoholism13
    1392CRHcorticotropin releasing hormone8q13Alcoholism1
    Page: 1 2 3 4 list all