Found 80 literature records

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Entrez ID	Description
4771	Novel alternatively spliced isoforms of the neurofibromatosis type 2 tumor suppressor are targeted to the nucleus and cytoplasmic granules.
50514	"Isolation and mutational analysis of a novel human cDNA, DEC1 (deleted in esophageal cancer 1), derived from the tumor suppressor locus in 9q32."
3621	Molecular analysis of the candidate tumor suppressor gene ING1 in human head and neck tumors with 13q deletions.
27086	The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p.
7157	Squamous cell carcinoma of the head and neck shows a high incidence of p53 tumor suppressor gene alterations; the latter therefore appears to play an important role in the pathogenesis and progression of such neoplasms.
54556	"Allelic loss and reduced expression of the ING3, a candidate tumor suppressor gene at 7q31, in human head and neck cancers."
7249	Tuberous sclerosis complex tumor suppressor-mediated S6 kinase inhibition by phosphatidylinositide-3-OH kinase is mTOR independent.
2296	FOXC1 functions as a tumor suppressor through TGF-beta1 mediated signals.
54984	Data show that liver-related putative tumor suppressor gene (LPTS) mutations occur in hepatocellular carcinoma but are infrequent and of little effect on the telomerase inhibitory function of the protein.
5920	"Induction of TIG3, a putative class II tumor suppressor gene, by retinoic acid in head and neck and lung carcinoma cells and its association with suppression of the transformed phenotype."
27113	"PUMA suppresses tumor cell growth in head/neck cancer, but it does not appear to be a direct target of inactivation in head and neck tumorigenesis."
23261	FLJ10737 and CAMTA1 genes on 1p36.31-p36.23 are candidate tumor suppressor genes of neuroblastoma
55735	FLJ10737 and CAMTA1 genes on 1p36.31-p36.23 are candidate tumor suppressor genes of neuroblastoma
4221	"Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain."
6294	"REVIEW: possibility that SAFB1 and SAFB2 are novel breast tumor suppressor genes, and how they might function in this role, are discussed"
9667	"REVIEW: possibility that SAFB1 and SAFB2 are novel breast tumor suppressor genes, and how they might function in this role, are discussed"
91768	ik3-1/Cables has been identified to be a candidate tumor suppressor for colon and head/neck cancers.
1029	"The inactivation of the tumor suppressor gene p16 plays a role in the carcinogenesis of squamous cell carcinomas of the oral cavity, the pharynx and the larynx. There is no influence on the tumor dependent prognosis."
51147	Frequent deletion and decreased mRNA expression of ING4 suggested it as a class two tumor suppressor gene and may play an important role in head and neck cancer.
4830	These data imply that nm-23 may be tumor suppressor gene involved in neck squamous cell carcinomas but that it may not function as a tumor metastasis suppressor in high-stage laryngeal carcinoma.
26471	Com-1/p8 is a potential tumour suppressor in human prostate cancer.
1630	Deleted in colorectal cancer is a putative conditional tumor-suppressor gene inactivated by promoter hypermethylation in head and neck squamous cell carcinoma.
6273	"S100A2 was down-regulated in lymph node metastasis of squamous cell carcinoma, head and neck neoplasms (SCCHN), suggesting that instead of being a putative tumor suppressor, S100A2 may play a role in the metastasis of SCCHN"
2308	FOXO1 serves as a tumor suppressor in endometrial cancer cells and is involved in normal growth control and maintenance of genomic stability.
54556	ING3 would function as a potential tumor suppressor molecule and that low levels of ING3 may indicate an aggressive nature of head and neck cancer.
675	Molecular genetic analysis of the BRCA2 tumor suppressor gene region in cutaneous squamous cell carcinomas.
55743	"confirmed that the FHA domain of CHFR plays an important role in initiating a cell cycle arrest at G2/M, indicating a functional link exists between the anti-proliferative effects and checkpoint function of this tumor suppressor protein via this domain"
27250	mir-21 functions as an oncogene by a mechanism that involves translational repression of the tumor suppressor Pdcd4
7345	PGP9.5 is a tumor suppressor gene that is inactivated by promoter methylation or gene deletion in several types of human cancers.
79192	"Frequently methylated tumor suppressor genes in head and neck squamous cell carcinoma. Overexpression of the three most frequently down-regulated candidates, SLC5A8, IRX1, and EBF3, validated their tumor suppressor potential by growth curve analysis and colony formation assay."
160728	Frequently methylated tumor suppressor genes in head and neck squamous cell carcinoma.
3248	15-PGDH is a direct downstream effector of HNF3beta and acts as a tumor suppressor in lung cancer.
10152	"In this study, we found by using yeast two-hybrid screening that TRIM32 binds to Abl-interactor 2 (Abi2), which is known as a tumor suppressor and a cell migration inhibitor, and we showed that TRIM32 mediates the ubiquitination of Abi2."
84872	"ZC3H10 inhibits the anchorage independent growth of tumor cells, which is consistent with a tumor suppressor function."
2587	GALR1 is a tumor suppressor gene in head and neck squamous cell carcinoma
55743	"CHFR, a potential tumor suppressor, downregulates interleukin-8 through the inhibition of NF-kappaB."
5789	These results implicate PTPRD as a tumor suppressor on chromosome 9p that is involved in the development of glioblastoma multiforme and multiple human cancers.
3611	restoration of JNK1 in alveolar rhabdomyosarcoma reestablished a tumor-suppressive function for integrin-linked kinase
10217	High mutability of the tumor suppressor genes RASSF1 and RBSP3 (CTDSPL) in cancer.
11186	High mutability of the tumor suppressor genes RASSF1 and RBSP3 (CTDSPL) in cancer.
6595	Loss of heterozygosity at the 9p21-24 region and identification of BRM as a candidate tumor suppressor gene in head and neck squamous cell carcinoma.
406929	Results suggested miR-138 acts as a tumor suppresser and may serve as a therapeutic target for HNSCC patients at risk of metastasis.
406930	Results suggested miR-138 acts as a tumor suppresser and may serve as a therapeutic target for HNSCC patients at risk of metastasis.
7832	"Skp2 enhances polyubiquitination and degradation of TIS21/BTG2/PC3, tumor suppressor protein, at the downstream of FoxM1."
51696	Human HECA slows down cell division of oral squamous cell carcinoma cells and may therefore act as a tumor suppressor in head and neck cancer.
10152	"TRIM32 promotes cell migration through ubiquitination of Abl interactor 2 (Abi2), a tumor suppressor."
84289	Tumor-specific mutation and down-regulation of ING5 mRNA suggested it as a tumor suppressor gene in oral squamous cell carcinoma
84289	"ING5 may function as a tumor suppressor gene or oncogene tightly linked with p53 status, and may play an important role in the prognosis of head and neck squamous cell carcinoma (HNSCC) patients."
2309	Inhibition of FOXO3 tumor suppressor function by betaTrCP1 through ubiquitin-mediated degradation in a tumor mouse model.
10413	"YAP function as a tumor suppressor may alternatively be dysregulated by AKT phosphorylation at serine-127 and cytoplasmic sequestration, or by transcriptional repression by DeltaNp63, in different subsets of head and neck squamous cell carcinomas (HNSC..."

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