Found 616 literature records

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Entrez ID	Description
401	"PHOX2A gene, localized in a tumor suppressor candidate region at 11q, weas screened for mutations by DNA sequencing in 47 tumors of different stages."
672	Tumor suppressor BRCA1 is expressed in prostate cancer and controls insulin-like growth factor I receptor (IGF-IR) gene transcription in an androgen receptor-dependent manner.
1969	"Downregulation of EphA2 significantly inhibited invasion, proliferation and clonogenicity in vitro and suppressed tumorigenicity in vivo. Data provides the first in vivo evidence demonstrating a direct role for EphA2 in promoting melanoma tumorigenicity."
10612	Loss of heterozygosity of chromosome segment 11p15.5 in malignant gliomas suggests TRIM3 as a candidate brain tumor suppressor gene.
1946	"ephrinA5 acted as a tumor suppressor in glioma, and its negative regulation of EGFR contributed to the suppressive effects."
6598	INI1 is the primary tumor suppressor gene involved in the development of rhabdoid tumors with no second locus identified.
324	GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon.
7078	candidate tumor suppressor gene in the biliary tree
11197	analyzed 5 osteosarcoma cell lines in a high-throughput screen for epigenetically silenced tumor suppressor genes and identified Wnt inhibitory factor 1 (WIF1) as a candidate tumor suppressor gene
10154	"significant loss of Plexin C1 in metastatic melanoma compared with primary melanoma, suggesting the possibility that the Plexin C1 receptor is a tumor suppressor protein for melanoma"
8848	TSC-22 normally contributes to the regulation of hematopoietic stem cell function and is a putative tumor suppressor gene that is hypermethylated and silenced in T or NK LGL leukemia.
8633	UNC5C might act as a tumor suppressor and UNC5C methylation might present a malignant potential in colorectal cancer.
1029	p16 might act as a tumor suppressor in colorectal carcinomas and was more frequently methylated in advanced colorectal carcinomas.
864	Regulation of RUNX3 tumor suppressor gene expression in cutaneous melanoma.
6794	"LKB1 is thus a major cervical tumor suppressor, demonstrating that acquired genetic alterations drive progression of HPV-induced dysplasias to invasive, lethal cancers"
6273	"Diminished expression of S100A2, a putative tumor suppressor, is an independent predictive factor of neck node relapse in laryngeal squamous cell carcinoma."
7020	these studies support a tumor suppressor role for AP-2alpha in the gastrointestinal tract
7020	these studies support a tumor suppressor role for AP-2alpha in the gastrointestinal tract.
7128	TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma.
6925	ITF-2B is a tumor suppressor that has an important function at the adenoma to carcinoma transition.
1029	Increased senescence as mediated by the p16(INK4A) tumor suppressor has only a minor function as an intrinsic regulator of steady-state HSC ageing in vivo.
6041	"support a model in which the RNase-L-mediated degradation of ribosomal protein mRNAs inhibits translation, and may contribute to its antiproliferative, senescence inducing and tumor suppressor activities."
4045	results show that LSAMP is a novel candidate tumor suppressor gene in osteosarcomas
5333	PLCD1 acts as a functional tumor suppressor involved in gastric carcinogenesis.
1029	Expression of the Arf tumor suppressor gene is controlled by Tgfbeta2 during development.
5789	These results implicate PTPRD as a tumor suppressor on chromosome 9p that is involved in the development of glioblastoma multiforme and multiple human cancers.
5795	Tumor suppressor density-enhanced phosphatase-1 (DEP-1) inhibits the RAS pathway by direct dephosphorylation of ERK1/2 kinases.
11186	The epigenetic silencing of tumor suppressor genes involved in the Ras/PI3K/AKT pathway plays an important role in oral squamous cell carcinoma radioresistance
92304	The epigenetic silencing of tumor suppressor genes involved in the Ras/PI3K/AKT pathway plays an important role in oral squamous cell carcinoma radioresistance
9770	The epigenetic silencing of tumor suppressor genes involved in the Ras/PI3K/AKT pathway plays an important role in oral squamous cell carcinoma radioresistance
84417	"The restoration of ECRG4 expression in ESCC cells inhibited cell proliferation, colony formation, cell cycle progression and tumor growth in vivo. ECRG4 is a novel candidate tumor suppressor gene in ESCC."
54766	these data support BTG4 as a candidate tumor suppressor gene that is epigenetically silenced in the majority of gastric cancers.
324	A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis.
4089	A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis.
406906	MicroRNA-122a functions as a novel tumor suppressor downstream of adenomatous polyposis coli in gastrointestinal cancers.
7128	TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas.
4692	Confirmation of NDN as a tumor suppressor may have implications for monitoring of PWS patients and could present a novel cancer therapeutic target
7428	"Novel insights into the role of the tumor suppressor von Hippel Lindau in cellular differentiation, ciliary biology, and cyst repression."
27250	"Hyaluronan-CD44 interaction with protein kinase C(epsilon) promotes oncogenic signaling by the stem cell marker Nanog and the Production of microRNA-21, leading to down-regulation of the tumor suppressor protein PDCD4, anti-apoptosis, and chemotherapy resistance in breast tumor cells."
4015	Genetic polymorphism as a mechanism of impaired tumor suppressor function of LOX-propeptide and it may play an etiologic role in ER-negative breast cancer.
1029	"The results unveil a backup tumor suppressor role for p16(Ink4a) in the event of p53 inactivation, expanding our understanding of how p16(Ink4a) expression is regulated in vivo."
23365	LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer
112399	"PHD3 appears to be a tumor suppressor in colorectal cancer cells that inhibits IKKbeta/NF-kappaB signaling, independent of its hydroxylase activity."
6598	Loss of the SNF5 tumor suppressor acting through BRG1 is associated with neoplasms.
3685	This study shows that alpha(v)beta(3)-integrin expression on tumor cells actually slows tumor progression and acts as a tumor suppressor.
3690	This study shows that alpha(v)beta(3)-integrin expression on tumor cells actually slows tumor progression and acts as a tumor suppressor.
26038	CHD5 is a tumor suppressor gene epigenetically down-regulated in gastric cancer
5925	Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer.
644943	RASSF10 may encode a novel epigenetically inactivated candidate tumor suppressor gene in thyroid carcinogenesis.
1540	Tumor suppressor cylindromatosis: expressed in IgA nephropathy and negatively associated with renal tubulo-interstitial lesion.

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