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Dataset Description
  • Dataset Name: 16618939
  • Species: Mouse
  • Method: Microarray
  • No. of Genes: 71
  • Tissue: Whole brain
  • Phenotype: Alcohol preference
  • Publication: Mulligan et al. Proc Natl Acad Sci U S A. (2006) Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. PubMed
  • Dataset Summary: Microarray analyses of brain gene expression in three selected lines, and six isogenic strains of mice known to differ markedly in voluntary alcohol consumption provided >4.5 million data points for a meta-analysis. A total of 107 arrays were obtained and arranged into six experimental data sets, allowing the identification of 3,800 unique genes significantly and consistently changed between all models of high or low amounts of alcohol consumption. Here we select the 75 genes with the largest effect size (|d|) and lowest Q values.

    Gene list of this dataset (71 genes)
    Page: 1 2 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    66411Tbcbtubulin folding cofactor B7 B1Ckap1 
    66077Aurkaip1aurora kinase A interacting protein 14 E2|4 83.0 cM0610033H09Rik 
    715669030425E11RikRIKEN cDNA 9030425E11 gene9 A5.19030425E11Rik 
    68035Rbm42RNA binding motif protein 427 B13100004P22Rik 
    23948Mmp17matrix metallopeptidase 175 G1.3|5 72.5 cMMmp17 
    26921Map4k4mitogen-activated protein kinase kinase kinase kinase 4-Map4k4 
    12345Capzbcapping protein (actin filament) muscle Z-line, beta4 D3|4 66.8 cMCapzb 
    52174D4Ertd196eDNA segment, Chr 4, ERATO Doi 196, expressed4 D2.3|4 65.7 cMD4Ertd196e 
    11803Aplp1amyloid beta (A4) precursor-like protein 17 B1|7 8.0 cMAplp1 
    51788H2afzH2A histone family, member Z3 G3H2afz 
    67389C1qdc2C1q domain containing 24 E2|4 83.0 cM1110035L05Rik 
    13135Dad1defender against cell death 114 C2|14 24.0 cMDad1 
    19243Ptp4a1protein tyrosine phosphatase 4a11 BPtp4a1 
    16010Igfbp4insulin-like growth factor binding protein 411 DIgfbp4 
    76829Dok5docking protein 52 H3|2 99.0 cMDok5 
    77065Ints7integrator complex subunit 71 H65930412E23Rik 
    15939Ier5immediate early response 51 G3|1 81.5 cMIer5 
    13007Csrp1cysteine and glycine-rich protein 11 E4Csrp1 
    27379Tcl1b1T-cell leukemia/lymphoma 1B, 112 ETcl1b1 
    12282Hyou1hypoxia up-regulated 19 BHyou1 
    15331Hmgn2high mobility group nucleosomal binding domain 24 D3|4 62.2 cMHmgn2 
    101214Tra2atransformer 2 alpha homolog (Drosophila)6 B2.31500010G04Rik 
    17967Ncam1neural cell adhesion molecule 19 A5.3|9 28.0 cM1426865_a_at 
    14688Gnb1guanine nucleotide binding protein (G protein), beta 14 E2|4 79.4 cMGnb1 
    14688Gnb1guanine nucleotide binding protein (G protein), beta 14 E2|4 79.4 cM1454696_at 
    Page: 1 2 list all