Found 616 literature records

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Entrez ID	Description
5276	Notable genes include hypoxia and tumor growth regulator Loxl2 [26] and tumor suppressor Serpini2.
5101	Our results suggest that PCDH9 might function as a tumor suppressor during cancer development and progression
6424	These results support a role for SFRP4 as a tumor suppressor gene in ovarian cancers.
406919	microRNAs that jointly act as tumor suppressors in prostate carcinoma
406988	microRNAs that jointly act as tumor suppressors in prostate carcinoma
55384	MEG3 noncoding RNA: a tumor suppressor.
55384	MEG3 noncoding RNA: a tumor suppressor. These lines of evidence strongly suggest that MEG3 functions as a novel lncRNA tumor suppressor.
10788	observations strongly indicate that IQGAP2 is a surveillance type of tumour suppressor for prostate cancer
960	"CD44, as expressed by LS174T colon carcinoma cells, functions as a tumor suppressor. When the expression of CD44 is silenced, we see a dramatic increase in metastatic potential"
10550	PRAF3 plays an important role in the regulation of tumor progression and metastasis and serves as a tumor suppressor in human ESCC. We propose that PRAF3 might be used as a potential therapeutic agent for human ESCC.
574453	our findings suggest that miR-495 and miR-551a both act as tumor suppressors by targeting the PRL-3 oncogene and inhibiting gastric cancer cell migration and invasion.
693135	our findings suggest that miR-495 and miR-551a both act as tumor suppressors by targeting the PRL-3 oncogene and inhibiting gastric cancer cell migration and invasion.
406959	"The results suggest that as a tumor suppressor miRNA, miR-183 plays an important role in the aggressiveness of osteosarcoma."
284406	ZNF545 acts as a functional tumour suppressor in gastric cancer by inhibiting rRNA transcription.
159989	suggest that CCDC67 is a putative tumor suppressor gene that is silenced in gastric cancers by promoter CpG methylation and that it may play an important role in cell signaling and migration related to tumorigenesis
2273	"FHL1 is a methylation-silenced tumor-suppressor gene on chromosome X in gastrointestinal cancers, and that its silencing contributes to the formation of an epigenetic field for cancerization."
1832	"DSP is inactivated in lung cancer by an epigenetic mechanism, increases the sensitivity to anticancer drug-induced apoptosis and has tumor-suppressive function, possibly through inhibition of the Wnt/beta-catenin signaling pathway in NSCLC cells."
2042	Cancer-associated EPHA3 mutations attenuate the tumor-suppressive effects of normal EPHA3 in lung cancer.
406988	MiR-205 is an epigenetically regulated tumor suppressor that targets MED1.
406988	"Low levels of melanoma cell miR-205 expression as quantified by ISH show worse outcome, supporting the role of miR-205 as a tumor suppressor miRNA."
1045	"CDX2 is frequently methylated in lung cancer, and expression of CDX2 is regulated by promoter region hypermethylation. CDX2 may serve as a tumor suppressor in lung cancer and inhibits lung cancer cell proliferation by suppressing Wnt signaling."
442915	"miR-370 may function as a tumor suppressor by targeting FoxM1, and the epigenetic silence of miR-370 thus leads to derepression of FoxM1 expression and consequently contributes to AML development and progression."
406976	miR-199a-5p can regulate CAC1 and function as a tumor suppressor in colorectal cancer.
56999	ADAMTS9 acts as a functional tumor suppressor in gastric cancer through inhibiting oncogenic AKT/mTOR signaling pathway
27253	"PCDH17 acts as a tumour suppressor, exerting its anti-proliferative activity through inducing apoptosis and autophagy, and is frequently silenced in gastric and colorectal cancers."
1825	The p53 target gene desmocollin 3 acts as a novel tumor suppressor through inhibiting EGFR/ERK pathway in human lung cancer.
5100	study demonstrates the epigenetic inactivation of PCDH8 by promoter methylation and its tumor suppressor function in gastric cancer
142	"Atudies identify novel functions of PARP-1 in promoting disease progression, and ultimately suggest that the dual functions of PARP-1 can be targeted in human prostate cancer to suppress tumor growth and progression to castration resistance."
407040	MicroRNA-34 suppresses breast cancer invasion and metastasis by directly targeting Fra-1.
4640	findings suggest that MYO1A has tumor suppressor activity in the normal gastric epithelium but not in the normal endometrium and inactivation of MYO1A either genetically or epigenetically may confer gastric epithelial cells a growth ad
407010	"CREB promotes gliomagenesis and acts as a modulator of oncogenic mir-23a, which represses the tumor suppressor PTEN."
1036	CDO1 as a novel tumor suppressor gene and a potentially valuable molecular marker for human cancer
51339	These findings provided insight into the role of DACT1 as a novel functional tumor suppressor in gastric cancer through inhibiting NF-kappaB signaling pathway.
10562	OLFM4 may function as a tumor suppressor and an anti-metastatic gene during tumor progression
407044	"miR-7-5p may represent a novel tumor suppressor miRNA in melanoma, acting at least in part via its inhibition of IRS-2 expression and oncogenic Akt signaling."
407045	"miR-7-5p may represent a novel tumor suppressor miRNA in melanoma, acting at least in part via its inhibition of IRS-2 expression and oncogenic Akt signaling."
407043	"miR-7-5p may represent a novel tumor suppressor miRNA in melanoma, acting at least in part via its inhibition of IRS-2 expression and oncogenic Akt signaling.[mirna-7-5p]"
6688	Data suggest that PU.1 is a potent tumor suppressor in classical Hodgkin lymphoma (cHL) and that induction of PU.1 with demethylation agents and/or histone deacetylase inhibitors is a possible therapeutic option for patients with cHL.
10370	CITED2 is a direct effector of PPARgamma for tumor suppression.
407018	These data indicate that miR-27a contributes a tumor suppressor-like activity in acute leukemia cells via regulation of apoptosis
57167	The mechanism of SALL4 in promoting leukemogenesis is at least in part mediated by its repression of the tumor suppressor phosphatase and tensin homolog deleted on chromosome 10 (PTEN) through its interaction with a histone deacetylase (HDAC) complex.
664616	miR-487b is a tumor suppressor microRNA silenced by epigenetic mechanisms during tobacco-induced pulmonary carcinogenesis.
406913	miR-126&126* restored expressions play a tumor suppressor role by directly regulating ADAM9 and MMP7 in melanoma.
406943	Our findings suggest that miR-152 can act as a tumor suppressor that targets TGFalpha. miR-152 is a promising molecular target that inhibits prostate cancer cell migration and invasion.
79648	"in addition to its role in brain development, MCPH1 also functions as a tumor suppressor gene and is regulated by miR-27a"
4486	"the function of RON in tumors may be multidimensional, not just as a tumor suppressor or oncogene."
140690	"CTCF and BORIS suppressed breast cancer growth; findings provide further evidence that CTCF behaves as a tumor suppressor, and show BORIS has a similar growth inhibitory effect in vitro and in vivo"
137970	UNC5D is a functional tumor suppressor that is frequently downregulated in RCCs due to promoter hypermethylation and LOH.
4854	Results reveal a novel function of Notch3 in senescence regulation and tumor suppression.
406969	we showed that miR-194 have tumor suppressor effects on RCC by reducing the cellular migration and invasion abilities.

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