Found 476 literature records

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Entrez ID	Description
9368	EBP50 exerts tumor suppressor activity by promoting cell apoptosis and retarding extracellular signal-regulated kinase activity.
4763	"In addition to gains of 1q and 5p, and losses of 10p and 13q14 approximately q22, this tumor had also losses of two regions to which tumor suppressor genes are mapped: 1p36 (SDHB) and 17q11.2 (NF1)"
6390	"In addition to gains of 1q and 5p, and losses of 10p and 13q14 approximately q22, this tumor had also losses of two regions to which tumor suppressor genes are mapped: 1p36 (SDHB) and 17q11.2 (NF1)"
347745	"Results suggest that, in breast cancer, Par-4 plays a similar tumor suppressor gene role as reported in endometrial carcinoma, and that Par-4 expression has a significant inverse association with expression of progesterone receptor."
5074	"Results suggest that, in breast cancer, Par-4 plays a similar tumor suppressor gene role as reported in endometrial carcinoma, and that Par-4 expression has a significant inverse association with expression of progesterone receptor."
2051	Findings suggest a new role for EphB6 in suppressing cancer invasiveness and cell attachment through c-Cbl-dependent signaling.
672	"Study established a robust assay system to analyze the function of BRCA1 in regulating homologous recombination, which is critical for its tumor suppressor function."
1316	Nuclear expression of KLF6 tumor suppressor factor is highly associated with overexpression of ERBB2 oncoprotein in ductal breast carcinomas.
23410	"These results identify SIRT3 as a genomically expressed, mitochondria-localized tumor suppressor."
54971	Heat-shock protein 70 binds to a novel sequence in 5' UTR of tumor suppressor SMAR1 and regulates its mRNA stability upon Prostaglandin A2 treatment.
3090	A potential tumor suppressor role for Hic1 in breast cancer through transcriptional repression of ephrin-A1.
301	"ANXA1, which was recently reported as a possible tumor suppressor gene, can protect cells from heat-induced growth arrest and DNA damage in breast cancer cells."
7703	BMI1 acts as an oncogene and Mel-18 functions as a tumor suppressor via downregulation of BMI1.
7490	The Wilms' tumor suppressor WT1 induces estrogen-independent growth and anti-estrogen insensitivity in ER-positive breast cancer MCF7 cells.
29117	BRD7 is a candidate tumour suppressor gene required for p53 function.
10181	"RBM5/H37 tumor suppressor, located at the lung cancer hot spot 3p21.3, alters expression of genes involved in metastasis."
406989	"Studies indicate that loss of tumor suppressor miR-206, and the overexpression of oncogenic miR-21 have been observed in many breast cancers."
675	Evidence that the tumor-suppressor protein BRCA2 does not regulate cytokinesis in human cells.
115761	"The role of the allelic variants in ARLTS1, RAD51 and MDM2 acting in the tumor suppressor, DNA repair and p53 pathways as risk factors for familial breast cancer in 147 patients displaying characteristics of familial disease, was investigated."
672	HOXA9 restricts breast tumor aggression by modulating expression of the tumor suppressor gene BRCA1
6794	"Adiponectin treatment increases the expression of tumor suppressor gene, LKB1 in breast cancer cells."
388	"miR-21 promotes multiple components of the metastatic phenotype in vitro by regulating several important tumor suppressors, including RHOB."
167465	DC-SCRIPT can act as a tumor suppressor in breast cancer development.[review]
55294	The Fbw7 tumor suppressor targets KLF5 for ubiquitin-mediated degradation and suppresses breast cell proliferation.
51147	A dominant mutant allele of the ING4 tumor suppressor found in human cancer cells exacerbates MYC-initiated mouse mammary tumorigenesis.
5074	Down-regulation of the candidate tumor suppressor gene PAR-4 is associated with poor prognosis in breast cancer.
100302232	MIR-1226 functions as a tumor suppressor by promoting the induction of cell death.
23336	SYNM could represent a novel putative breast tumor suppressor gene that is prone to epigenetic silencing. SYNM promoter methylation may become a useful predictive biomarker to stratify breast cancer patients' risk for tumor relapse.
672	Presymptomatic breast cancer in Egypt: role of BRCA1 and BRCA2 tumor suppressor genes mutations detection.
675	Presymptomatic breast cancer in Egypt: role of BRCA1 and BRCA2 tumor suppressor genes mutations detection.
54904	NSD3L depletion increased the invasiveness of MDA-MB-231 breast cancer cells indicating that NSD3L normally restrain cellular metastatic potential. Together the presented data indicates that NSD3L is a candidate tumor suppressor.
406961	Altered expression of the novel tumor suppressor miR-185 may be one of the central events that leads to dysregulation of oncogenic protein Six1 in human cancers.
27302	Bone morphogenetic protein-10 (BMP-10) may function as a tumor suppressor in breast cancer.
672	"Methylation of the tumor suppressor protein, BRCA1, influences its transcriptional cofactor function."
29117	Here we further discuss the role of BRD7 as a cofactor in transcriptional regulation and highlight its role as a tumor suppressor via association with p53 and other tumor suppressor proteins.
5071	"Allelic loss of 6q25-27, the PARKIN tumor suppressor gene locus, in cervical carcinoma."
5333	"PLCD1 is silenced by promoter methylation in breast cancer. Silencing of PLCD1 is reversed by demethylation which leads to the disruption of cell cycle at G2/M phase in breast cancer, indicating that PLCD1 functions as a tumor suppressor in this tumor."
84911	ZNF382 is a functional tumor suppressor frequently methylated in multiple carcinomas.
91133	"identified L3MBTL4 as a potential tumor suppressor gene of chromosome arm 18p. The gene is targeted by deletion, breakage and mutations and its mRNA is downregulated in breast tumors"
675	The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA.
54583	Data suggest that PHD2/HIF-2/amphiregulin signaling has a critical role in the regulation of breast tumor progression and propose PHD2 as a potential tumor suppressor in breast cancer.
23513	"hScrib, a human homolog of Drosophila neoplastic tumor suppressor, is involved in the progress of endometrial cancer."
11186	"RASSF1C, unlike RASSF1A, is not a tumor suppressor, but instead may play a role in stimulating metastasis and survival in breast cancer ce"
50943	FOXP3 as an X-linked tumor suppressor.
5795	Germline epigenetic silencing of the tumor suppressor gene PTPRJ in early-onset familial colorectal cancer.
672	"BRCA1 modulates the expression of hnRNPA2B1 and KHSRP involved in the processing of RNA, highlighting the complex nature of BRCA1-associated tumor suppressor function and disclosing a novel mechanism by which BRCA1 may affect transcription."
472	these results elucidate a novel mechanism through which the TGF-beta pathway regulates the cancer stem cells property by interfering with the tumor suppressor ATM.
8821	INPP4B functions as a tumor suppressor by negatively regulating normal and malignant mammary epithelial cell proliferation through regulation of the PI3K/Akt signaling pathway
5781	SHP-2 as an essential component of tumor suppression and anoikis mediated by SIRPalpha1 in human breast carcinoma cells as well as in v-Src-transformed cells.
23411	Studies provide novel evidence for a checkpoint function of Sirt1 in the development of PIN and further highlight a role for SIRT1 as a tumor suppressor in the prostate.

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