Found 616 literature records

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Entrez ID	Description
406970	we showed that miR-194 have tumor suppressor effects on RCC by reducing the cellular migration and invasion abilities.
286319	Results support TUSC1 has tumor suppressor activity as a candidate tumor suppressor gene located on chromosome 9p.
8784	GITR acts as a potential tumor suppressor in MM.
5494	PPM1A is a RelA phosphatase that regulates NF-kappaB activity and that PPM1A has tumor suppressor-like activity.
64579	NDST4 gene is a novel candidate tumor suppressor gene in human cancer.
4502	MT2A might play a tumor suppressive activity through inhibiting NF-kappaB signaling
889	"Our findings suggest that miR-21 promotes tumor cell growth, at least in part, by down-modulating the potential tumor suppressor KRIT1."
49860	Findings demonstrate that CRNN is a tumor suppressor gene that plays a critical tumor suppressive role in ESCC.
574452	overexpressed in hepatocellular carcinoma and aids in transformation by regulating the G1/S cell cycle transition through targeting of the Mutated in Colorectal Cancer tumor suppressor
563	AZGP1 might serve as a candidate tumor suppressor and a potential prognostic biomarker in gastric carcinogenesis.
56475	"Reprimo expression is normally induced in response to DNA damage, acting as a novel tumor suppressor in gastric cancer; however, Reprimo methylation abrogates its expression and effects"
406899	MIR-106a-5p functions as a tumor suppressor during the development of astrocytomas by targeting FASTK.
406906	There is a double-negative feedback loop between a tumor suppressor (miR-122) and an oncogene (c-Myc) in hepatocellular cancer.
406917	"The results show that miR-129-1-3p and miR-129-5p, are down-regulated in gastric cancer cell lines and all of the mature products of miR-129 showed tumor suppressor activities."
406918	"The results show that miR-129-2-3p and miR-129-5p, are down-regulated in gastric cancer cell lines and all of the mature products of miR-129 showed tumor suppressor activities."
6125	"Unlike other tumor suppressors, RPL5 and RPL11 play essential roles in normal cell proliferation."
6135	"Unlike other tumor suppressors, RPL5 and RPL11 play essential roles in normal cell proliferation."
90993	CREB3L1 plays an important role in suppressing tumorigenesis and that loss of expression is required for the development of a metastatic phenotype.
11095	Study uncovers the tumor suppressive function of ADAMTS8 and its frequent methylation in certain tumors could be developed as a potential biomarker.
100126306	miR-888 functions to promote prostate cancer progression and can suppress protein levels of the tumor suppressor genes RBL1 and SMAD4.
1788	provide evidence that Dnmt3a and Dnmt3b function as tumor suppressor genes in the prevention of lymphoid malignancies in mice.
4921	Loss of DDR2 suppresses tumor angiogenesis and tumor metastasis to the lung.
1528	Results define CYB5A as a novel prognostic factor for PDAC that exerts its tumor-suppressor function through autophagy induction and TRAF6 modulation.
574408	Data indicate that overexpression of KDM1A partially reversed the tumor suppressive effects of miR-329 in neuroblastoma cells.
51700	"findings suggest that CYB5R2 may be a functional tumor suppressor gene, frequently inactivated by hypermethylation of its promoter in nasopharyngeal carcinoma"
4826	Data suggest NNAT as a potential tumor suppressor in myxoid liposarcomas.
406957	"results demonstrated that miR-181c inhibits neuroblastoma cell growth and metastasis-related traits through the suppression of Smad7, functioning as a tumor suppressor"
6924	TCEB3C is a putative tumor suppressor gene of small intestinal neuroendocrine tumors
338442	GPR109A is a tumor suppressor in mammary gland.
407051	"results revealed that miR-9-3 was a tumor suppressor miRNA hypermethylated in chronic lymphocytic leukemia, which was associated with down-regulation of NFKB1 protein."
7982	The tumor suppressor ST7 is a key gene silenced by PRMT5.
574476	Our results provide evidence that the tumor suppressor effect of miR-520c-3p is mediated through repression of translation while inducing senescence and that eIF4GII is a key effector of this anti-tumor activity.
6387	"These data demonstrate a functional tumor suppressive role for the normal expression of CXCL12 in pancreatic ducts, regulating both tumor growth andcellulardissemination to metastatic sites."
5770	Findings implicate PTPN1 as a tumor suppressor gene in Primary mediastinal B-cell lymphoma and classical Hodgkin lymphoma and suggest that loss of PTPN1 phosphatase activity may promote the development of these cancers.
79798	Inherited autosomal dominant mutations in the ARMC5 gene are a frequent cause of primary macronodular adrenal hyperplasia. Biallelic inactivation of ARMC5 is consistent with its role as a potential tumor suppressor gene.
100126329	MIR941 and MIR1247 are transcriptionally regulated by DNA methylation in gastric cancer and that they have tumor suppressor properties through their inhibition of key cancer promoting genes in this context.
100302145	MIR941 and MIR1247 are transcriptionally regulated by DNA methylation in gastric cancer and that they have tumor suppressor properties through their inhibition of key cancer promoting genes in this context.
5316	deficiency of tumor suppressor prep1 accelerates the onset of meis1- hoxa9 leukemogenesis
5789	"We reveal that PTPRD is a bona fide tumor suppressor, pinpoint PTPRD loss as a cause of aberrant STAT3 activation in gliomas, and establish PTPRD loss, in the setting of CDKN2A/p16(INK4A) deletion, as a driver of glioma progression."
4045	"The tumor suppressor function of LSAMP is most likely exerted by reducing the proliferation rate of the tumor cells, possibly by indirectly upregulating one or more of the genes HES1, CTAG2 or KLF10."
1843	"Together, our results clearly establish the role of Dusp1 as a tumor suppressor gene that regulates cancer-associated inflammation."
26260	FBXO25 functions as a haploinsufficient tumor suppressor in mantle cell lymphoma.
406943	miR-152 mediates the tumor-suppressive effects that knockdown of XIST exerts in glioblastoma stem cells.
7982	Allelic loss at 7q31.1 in human primary ovarian carcinomas suggests the existence of a tumor suppressor gene.
7490	The tumor suppressor gene WT1 inhibits ras-mediated transformation.
7982	Loss of heterozygosity in human primary prostate carcinomas: a possible tumor suppressor gene at 7q31.1.
1029	Somatic mutations of the MTS (multiple tumor suppressor) 1/CDK4l (cyclin-dependent kinase-4 inhibitor) gene in human primary non-small cell lung carcinomas.
4771	The neurofibromatosis 2 (NF2) tumor suppressor gene encodes multiple alternatively spliced transcripts.
7428	Somatic mutations of the von Hippel-Lindau tumor suppressor gene in sporadic central nervous system hemangioblastomas.
1630	Point mutations and allelic deletion of tumor suppressor gene DCC in human esophageal squamous cell carcinomas and their relation to metastasis.

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