Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
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Found 616 literature records
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Entrez ID
Description
55294
FBXW7/hCDC4 is a general tumor suppressor in human cancer.
7428
Allele-specific regulation of primary cilia function by the von Hippel-Lindau tumor suppressor.
2903
NMDAR2A is commonly hypermethylated in primary human colorectal carcinoma and possesses tumor-suppressive activity.
3621
the interaction between Alien and the tumor suppressors p33ING1 and p33ING2 reveals a novel cellular protein network
3622
the interaction between Alien and the tumor suppressors p33ING1 and p33ING2 reveals a novel cellular protein network
1029
"Loss of heterozygosity (LOH) of the hDMP1 gene was detectable in approximately 35% of human lung carcinomas, which was found in mutually exclusive fashion with LOH of INK4a/ARF or that of P53. DMP1 is a pivotal tumor suppressor for human lung cancers."
7157
"Loss of heterozygosity (LOH) of the hDMP1 gene was detectable in approximately 35% of human lung carcinomas, which was found in mutually exclusive fashion with LOH of INK4a/ARF or that of P53. DMP1 is a pivotal tumor suppressor for human lung cancers."
9988
"Loss of heterozygosity (LOH) of the hDMP1 gene was detectable in approximately 35% of human lung carcinomas, which was found in mutually exclusive fashion with LOH of INK4a/ARF or that of P53. DMP1 is a pivotal tumor suppressor for human lung cancers."
1029
N-ethyl-N-nitrosourea (ENU)-induced meningiomatosis and meningioma in p16(INK4a)/p19(ARF) tumor suppressor gene-deficient mice.
10395
"Tumor-specific methylation of the 8p22 tumor suppressor gene DLC1 is an epigenetic biomarker for Hodgkin, nasal NK/T-cell and other types of lymphomas."
231
Aldose reductase gene was identified in the genome-wide loss-of-function genetic screen as putative tumor suppressor located at 7q35.
2972
Brf1 gene was identified in the genome-wide loss-of-function genetic screen as putative tumor suppressor located at 14q32.33.
9318
CSN2 gene was identified in the genome-wide loss-of-function genetic screen as putative tumor suppressor located at 15q21.2.
7428
The von hippel-lindau tumor suppressor protein: an update.
5333
Characterization of a novel tumor-suppressor gene PLC delta 1 at 3p22 in esophageal squamous cell carcinoma.
8651
SOCS-1 mutations qualify as a tumor suppressor in mediastinal b-cell lymphoma.
160728
Candidate tumor suppressor gene SLC5A8 is frequently down-regulated by promoter hypermethylation in prostate tumor.
10181
Promoter methylation study of the H37/RBM5 tumor suppressor gene from the 3p21.3 human lung cancer tumor suppressor locus.
112464
"hSRBC is a novel tumor suppressor whose epigenetic inactivation contributes to the malignant progression of gastric tumors, in part, through attenuated p53 response to stresses."
5925
Aberrant nucleocytoplasmic localization of the retinoblastoma tumor suppressor protein in human cancer correlates with moderate/poor tumor differentiation.
860
Runx2 functions as a tumor suppressor in primary diploid osteoblasts; subnuclear targeting contributes to Runx2-mediated tumor suppression.
9940
DLEC1 is a candidate tumor suppressor gene that plays an important role in the development and progression of hepatocellular carcinoma.
1687
DFNA5 is a novel tumor suppressor gene in CRC and a valuable molecular marker for human cancer
1029
Results indicate that TBX3 represses expression of p14(ARF) tumor suppressor in breast cancer.
5371
Modulation of M2-type pyruvate kinase activity by the cytoplasmic PML tumor suppressor protein.
6425
In its role as tumor suppressor gene. SFRP5 methylation may be a novel DNA-based biomarker potentially useful in clinical breast cancer management.
115761
A novel tumor suppressor gene [ARLTS1 (ADP-ribosylation factor-like tumor suppressor gene 1)]is found to be altered in human carcinogenesis. It is located in Chromosome 13q14.3.
1031
"Studies identify p18(INK4c) as a glioblastoma multiforme tumor suppressor gene, revealing an additional mechanism leading to aberrant activation of cyclin/cdk complexes in this terrible malignancy."
1029
These findings uncover a feedback regulatory circuit in the astrocytic lineage and demonstrate tumor suppressor role for p18(INK4C) in human glioblastoma wherein it functions cooperatively with other INK4 family.
1031
These findings uncover a feedback regulatory circuit in the astrocytic lineage and demonstrate tumor suppressor role for p18(INK4C) in human glioblastoma wherein it functions cooperatively with other INK4 family.
672
"These observations are consistent with the idea that BRCA2, but not BRCA1, is a tumor suppressor of prostate cancer."
675
"These observations are consistent with the idea that BRCA2, but not BRCA1, is a tumor suppressor of prostate cancer."
56999
These findings support ADAMTS9 as a putative tumor suppressor gene in vivo in NPC that is significantly associated with lymph node metastases.
139285
Tumor suppressor WTX gene mutation is rare in acute leukemias.
83593
Assessment of NORE1A as a putative tumor suppressor in human neuroblastoma.
3394
"IRF8 was identified as a functional tumor suppressor, which is frequently silenced by epigenetic mechanism in multiple carcinomas"
1871
deregulated expression of E2F3a causes DNA damage under physiological conditions and indicate that the ATM-dependent response to this damage is important for the induction of apoptosis and tumor suppression
407043
microRNA-7 (miR-7) is a potential tumor suppressor in glioblastoma targeting critical cancer pathways
407040
miR-34a is a tumor suppressor gene in human neuroblastoma
1474
Inactivation of the cystatin E/M tumor suppressor gene in cervical cancer.
7345
PGP9.5 is a tumor suppressor gene that is inactivated by promoter methylation or gene deletion in several types of human cancers.
407041
"miR-34b/c and BTG4 are novel tumor suppressors in colorectal cancer (CRC) and that the miR-34b/c CpG island, which bidirectionally regulates miR-34b/c and BTG4, is a frequent target of epigenetic silencing in CRC"
407042
"miR-34b/c and BTG4 are novel tumor suppressors in colorectal cancer (CRC) and that the miR-34b/c CpG island, which bidirectionally regulates miR-34b/c and BTG4, is a frequent target of epigenetic silencing in CRC"
54766
"miR-34b/c and BTG4 are novel tumor suppressors in colorectal cancer (CRC) and that the miR-34b/c CpG island, which bidirectionally regulates miR-34b/c and BTG4, is a frequent target of epigenetic silencing in CRC"
2137
Exostoses like-3 (EXTL3) is a putative tumour suppressor gene.
1029
Rearrangement and allelic imbalance on chromosome 5 leads to homozygous deletions in the CDKN2A/2B tumor suppressor gene region in rat endometrial cancer.
1030
Rearrangement and allelic imbalance on chromosome 5 leads to homozygous deletions in the CDKN2A/2B tumor suppressor gene region in rat endometrial cancer.
7428
Endothelial function of von Hippel-Lindau tumor suppressor gene: control of fibroblast growth factor receptor signaling.
2066
"Pregnancy and extended lactation durations have been correlated with reduced risk of breast cancer, and the role of ErbB4 in tumor suppression may therefore be linked with its role in lactation."
639
PRDM1 may be a tumor suppressor in some primary central nervous system lymphoma and contribute to lymphomagenesis by impairing terminal differentiation
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