Found 476 literature records

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Entrez ID	Description
672	These results support the existence of a heterozygous phenotype of BRCA1 and suggest that the loss of one BRCA1 allele may suppress the fitness advantage caused by the inactivation of other tumor suppressor genes.
10395	A novel isoform of the 8p22 tumor suppressor gene DLC1 suppresses tumor growth and is frequently silenced in multiple common tumors.
94241	TP53INP1 is a tumor suppressor in esophageal squamous cell carcinoma (ESCC0; c-Myc-mediated DNA methylation-associated silencing of TP53INP1 contributed to the pathogenesis of human ESCC.
8434	The tumor suppressor RECK interferes with HER-2/Neu dimerization and attenuates its oncogenic signaling.
26524	Identification of a tumor suppressor relay between the FOXP3 and the Hippo pathways in breast and prostate cancers.
50943	Identification of a tumor suppressor relay between the FOXP3 and the Hippo pathways in breast and prostate cancers.
442904	implicate the miR-335 locus on 7q32.2 as the first selective metastasis suppressor and tumor initiation suppressor locus in human breast cancer
51147	These results sustain the view that ING4 is a tumor suppressor in breast cancer and suggest that ING4 deletion may contribute to the pathogenesis of HER2-positive breast cancer.
5782	"Using a genetic screen, study identifies the PTPN12 tyrosine phosphatase as a tumor suppressor in triple-negative breast cancer (TNBC)."
675	A mitotic function for the high-mobility group protein HMG20b regulated by its interaction with the BRC repeats of the BRCA2 tumor suppressor.
11178	"Down-regulation of leucine zipper putative tumor suppressor 1 is associated with poor prognosis, increased cell motility and invasion, and epithelial-to-mesenchymal transition characteristics in human breast carcinoma."
54984	The telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in mice.
7157	The telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in mice.
406911	miR-125b is methylated and functions as a tumor suppressor by regulating the ETS1 proto-oncogene in human invasive breast cancer
8678	"Findings suggest a positive feedback loop for recruitment of FYVE-CENT and Beclin 1 to the intercellular bridge during cytokinesis, and reveal a novel potential tumor suppressor mechanism for Beclin 1."
407004	this study provides the first evidence that miR-22 restores the cellular senescence program in cancer cells and acts as a tumor suppressor.
9365	our results suggest that klotho is inactivated through promoter hypermethylation and potentially functions as a tumor suppressor gene in colorectal cancer
7048	TGF-? acts as a suppressor of primary tumor initiation but has been implicated as a promoter of the later malignant stages.
4015	the interaction of LOX-PP with Hsp70 and c-Raf inhibits a critical intermediate in Ras-induced MEK signaling and plays an important role in the function of this tumor suppressor
1602	"in cells growing in IGF-1 (and unresponsive to EGF), DACH1 is devoid of tumor suppressor activity."
9365	KL1 internal repeat mediates klotho tumor suppressor activities and inhibits bFGF and IGF-I signaling in pancreatic cancer.
659	BMPR2 has tumor-suppressive function in mammary epithelia and microenvironment and that disruption can accelerate mammary carcinoma metastases.
3091	"these findings provide that Mel-18 is a novel regulator of tumor angiogenesis through regulating HIF-1alpha and its target VEGF expressions mediated by the PTEN/PI3K/Akt pathway, suggesting a new tumor-suppressive role of Mel-18 in human breast cancer."
7428	Cancer cells promote survival through depletion of the von Hippel-Lindau tumor suppressor by protein crosslinking.
864	RUNX3 acts as a tumor suppressor in breast cancer by targeting estrogen receptor ??.
57659	ZBTB4 functions as a novel tumor-suppressor gene with prognostic significance for breast cancer survival
25855	Phosphorylation of RelA/p65 promotes DNMT-1 recruitment to chromatin and represses transcription of the tumor metastasis suppressor gene BRMS1.
23221	"RhoBTB2 (DBC2) functions as tumor suppressor via inhibiting proliferation, preventing colony formation and inducing apoptosis in breast cancer cells."
1111	"Thus, our study suggests that LOH11CR2A, PIG8 and CHEK1 are candidate tumor suppressor genes associated with breast carcinoma and have significant clinical as well as prognostic importance."
23328	The candidate tumor suppressor SASH1 interacts with the actin cytoskeleton and stimulates cell-matrix adhesion.
406901	Data demonstrate that miR-107 negatively regulates the tumor suppressor miRNA let-7 via a direct interaction.
79759	ZNF668 was identified as a novel breast tumor suppressor protein that regeulates the stability p53 tumor suppression proteins.
7020	Protein-binding microarray analysis of tumor suppressor AP2?? target gene specificity.
324	The tumor suppressor adenomatous polyposis coli controls the direction in which a cell extrudes from an epithelium.
4771	Loss of tumor suppressor Merlin in advanced breast cancer is due to post-translational regulation.
406887	JARID1B demethylase contributes to tumor cell proliferation through the epigenetic repression of a tumor suppressor miR
79577	The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination.
574508	miR-505 is a novel tumor suppressive miRNA and inhibits cell proliferation by inducing apoptosis
3663	IRF5 is an important tumor suppressor that regulates multiple cellular processes involved in the conversion of normal mammary epithelial cells to tumor epithelial cells with metastatic potential.
102800311	"In this review, author summarized the gene as tumor suppressor in table 2."
11191	"In this review, author summarized the gene as tumor suppressor in table 2."
283120	"In this review, author summarized the gene as tumor suppressor in table 2."
55384	"In this review, author summarized the gene as tumor suppressor in table 2."
60674	"In this review, author summarized the gene as tumor suppressor in table 2."
84417	"Down-regulation of ECRG4, a candidate tumor suppressor gene, in human breast cancer."
407019	"in neuroblastoma, miR-27b functions as a tumor suppressor by inhibiting the tumor-promoting function of PPARgamma, which triggers an increased inflammatory response"
25898	these data reveal the in vivo roles of Pirh2 in the regulation of p53 and c-Myc stability and support its role as a tumor suppressor
11186	Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines.
5889	unravel the critical role of RAD51C in the FA pathway of ICL repair and as a tumor suppressor.
407043	miR-7 functions as a tumor suppressor and plays a substantial role in inhibiting the tumorigenesis and reversing the metastasis of hepatocellular carcinoma through the PI3K/Akt/mTOR-signaling pathway in vitro and in vivo.

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