DegronMD

Uniprot ID: P98088

Source protein: Mucin-5AC

Source gene: MUC5AC

Class: DEG_SPOP_SBC_1

Location: 4260:4264

E3 ligase: SPOP

DEGRON score: 0.9795

ASA_SCORE: 87.12

COIL: 0.8834

CONS_SCORE: 0.3639

DSS_SCORE: 0.6846

HELIX: 0.0204

FCONS_SCORE: 1.2863

RIG_SCORE: 0.5977

Show entries

Search:

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.S4258G	SIDM01605	Non-Small Cell Lung Carcinoma	GDSC	VPSTS	DEG_SPOP_SBC_1	0.2778
p.P4257Q	SIDM00145	T-Lymphoblastic Leukemia	GDSC	VPSTS	DEG_SPOP_SBC_1	0.25

Showing 1 to 2 of 2 entries

Show entries

Search:

Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
No data available in table

Showing 0 to 0 of 0 entries

Show entries

Search:

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P0C6C1	Ankyrin repeat domain-containing protein 34C	DEG_SPOP_SBC_1	426:430	VPSTS	SPOP	0.9869	More...
Q92772	Cyclin-dependent kinase-like 2	DEG_SPOP_SBC_1	389:393	VPSTS	SPOP	0.9663	More...
Q96PU4	E3 ubiquitin-protein ligase UHRF2	DEG_SPOP_SBC_1	192:196	VPSTS	SPOP	0.993	More...
Q92574	Hamartin	DEG_SPOP_SBC_1	640:644	VPSTS	SPOP	0.9829	More...
Q5THJ4	Intermembrane lipid transfer protein VPS13D	DEG_SPOP_SBC_1	2123:2127	VPSTS	SPOP	0.9469	More...
Q9HCI5	Melanoma-associated antigen E1	DEG_SPOP_SBC_1	159:163	VPSTS	SPOP	0.9657	More...
P98088	Mucin-5AC	DEG_SPOP_SBC_1	4260:4264	VPSTS	SPOP	0.9795	More...
O95665	Neurotensin receptor type 2	DEG_SPOP_SBC_1	240:244	VPSTS	SPOP	0.8867	More...
Q6VY07	Phosphofurin acidic cluster sorting protein 1	DEG_SPOP_SBC_1	777:781	VPSTS	SPOP	0.9965	More...
P24386	Rab proteins geranylgeranyltransferase component A 1	DEG_SPOP_SBC_1	188:192	VPSTS	SPOP	0.9827	More...
Q86WV6	Stimulator of interferon genes protein	DEG_SPOP_SBC_1	351:355	VPSTS	SPOP	0.9975	More...
O94966	Ubiquitin carboxyl-terminal hydrolase 19	DEG_SPOP_SBC_1	938:942	VPSTS	SPOP	0.9914	More...
Q8TBF4	Zinc finger CCHC-type and RNA-binding motif-containing protein 1	DEG_SPOP_SBC_1	191:195	VPSTS	SPOP	0.989	More...

Showing 1 to 13 of 13 entries

DegronMD: protein-targeted degradation, mutation and drug response to degrons