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Dataset Description
  • Dataset Name: HuGE Navigator
  • Species: Human
  • Method: Literature data mining
  • No. of Genes: 188
  • Phenotype: Alcoholism
  • Publication: Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
  • Dataset Summary: HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.

    Gene list of this dataset (188 genes)
    Page: 1 2 3 4 list all   
    GeneIDSymbolNameGenetic locationPhenotypeNo. of Support Publications
    3106HLA-Bmajor histocompatibility complex, class I, B6p21.3Alcoholism1
    3107HLA-Cmajor histocompatibility complex, class I, C6p21.3Alcoholism1
    3176HNMThistamine N-methyltransferase2q22.1Alcoholism2
    3350HTR1A5-hydroxytryptamine (serotonin) receptor 1A5q11.2-q13Alcoholism2
    3351HTR1B5-hydroxytryptamine (serotonin) receptor 1B6q13Alcoholism12
    3352HTR1D5-hydroxytryptamine (serotonin) receptor 1D1p36.3-p34.3Alcoholism1
    3356HTR2A5-hydroxytryptamine (serotonin) receptor 2A13q14-q21Alcoholism11
    3358HTR2C5-hydroxytryptamine (serotonin) receptor 2CXq24Alcoholism5
    3361HTR5A5-hydroxytryptamine (serotonin) receptor 5A7q36.1Alcoholism1
    3362HTR65-hydroxytryptamine (serotonin) receptor 61p36-p35Alcoholism2
    3363HTR75-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)10q21-q24Alcoholism1
    3458IFNGinterferon, gamma12q14Alcoholism1
    3586IL10interleukin 101q31-q32Alcoholism3
    3552IL1Ainterleukin 1, alpha2q14Alcoholism1
    3553IL1Binterleukin 1, beta2q14Alcoholism2
    3554IL1R1interleukin 1 receptor, type I2q12Alcoholism1
    3557IL1RNinterleukin 1 receptor antagonist2q14.2Alcoholism2
    3630INSinsulin11p15.5Alcoholism1
    3952LEPleptin7q31.3Alcoholism1
    4023LPLlipoprotein lipase8p22Alcoholism1
    4049LTAlymphotoxin alpha (TNF superfamily, member 1)6p21.3Alcoholism1
    4128MAOAmonoamine oxidase AXp11.3Alcoholism15
    4129MAOBmonoamine oxidase BXp11.23Alcoholism1
    4159MC3Rmelanocortin 3 receptor20q13.2-q13.3Alcoholism1
    11343MGLLmonoglyceride lipase3q21.3Alcoholism1
    4311MMEmembrane metallo-endopeptidase3q25.1-q25.2Alcoholism1
    4314MMP3matrix metallopeptidase 3 (stromelysin 1, progelatinase)11q22.3Alcoholism1
    4524MTHFR5,10-methylenetetrahydrofolate reductase (NADPH)1p36.3Alcoholism5
    9NAT1N-acetyltransferase 1 (arylamine N-acetyltransferase)8p23.1-p21.3Alcoholism1
    4684NCAM1neural cell adhesion molecule 111q23.1Alcoholism2
    4790NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)4q24Alcoholism1
    4846NOS3nitric oxide synthase 3 (endothelial cell)7q36Alcoholism1
    4852NPYneuropeptide Y7p15.1Alcoholism9
    1728NQO1NAD(P)H dehydrogenase, quinone 116q22.1Alcoholism1
    4835NQO2NAD(P)H dehydrogenase, quinone 26pter-q12Alcoholism2
    4929NR4A2nuclear receptor subfamily 4, group A, member 22q22-q23Alcoholism1
    9369NRXN3neurexin 314q31Alcoholism1
    4915NTRK2neurotrophic tyrosine kinase, receptor, type 29q22.1Alcoholism1
    4985OPRD1opioid receptor, delta 11p36.1-p34.3Alcoholism4
    4986OPRK1opioid receptor, kappa 18q11.2Alcoholism4
    4987OPRL1opiate receptor-like 120q13.33Alcoholism2
    4988OPRM1opioid receptor, mu 16q24-q25Alcoholism20
    10280OPRS1opioid receptor, sigma 19p13.3Alcoholism1
    5020OXToxytocin, prepro- (neurophysin I)20p13Alcoholism1
    5021OXTRoxytocin receptor3p25Alcoholism1
    5080PAX6paired box 611p13Alcoholism1
    56117PCDHA@protocadherin alpha cluster5q31Alcoholism1
    5173PDYNprodynorphin20pter-p12Alcoholism2
    5179PENKproenkephalin8q23-q24Alcoholism2
    5295PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)5q13.1Alcoholism1
    Page: 1 2 3 4 list all