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All datasets list (sort by species):

Dataset_name or Publication PMIDSpeciesMethodTissuePhenotype or TreatmentPublication
11093800HumanMicroarraySH-SY5Y neuroblastoma cellsEthanol responseThibault et al. Mol Pharmacol. (2000) Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression. PubMed
11141048HumanMicroarrayFrontal cortexAlcohol dependence (AD)/Alcohol abuse/AlcoholismLewohl et al. Alcohol Clin Exp Res. (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. PubMed
12065639HumanMicroarrayFrontal and motor corticesAlcohol dependence (AD)/Alcohol abuse/AlcoholismMayfield et al. J Neurochem. (2002) Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. PubMed
12774316HumanMicroarrayTemporal cortexAlcohol dependence (AD)/Alcohol abuse/AlcoholismSokolov et al. J Neurosci Res. (2003) Transcription profiling reveals mitochondrial, ubiquitin and signaling systems abnormalities in postmortem brains from subjects with a history of alcohol abuse or dependence. PubMed
15236863HumanMicroarrayPrefrontal cortexAlcohol dependence (AD)/Alcohol abuse/AlcoholismIwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed
15816859HumanMicroarrayPrefrontal cortex and nucleus accumbensAlcohol dependence (AD)/Alcohol abuse/AlcoholismFlatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
16292326HumanMicroarrayFrontal cortexAlcohol dependence (AD)/Alcohol abuse/AlcoholismLiu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
18477577HumanAddiction array gene list  Hodgkinson et al. Alcohol Alcohol. (2008) Addictions Biology: Haplotype-Based Analysis for 130 Candidate Genes on a Single Array. PubMed
16894614HumanAssociation Alcohol dependence (AD)/Alcohol abuse/AlcoholismJohnson et al. Am J Med Genet B Neuropsychiatr Genet. (2006) Pooled association genome scanning for alcohol dependence using 104,268 SNPs: validation and use to identify alcoholism vulnerability loci in unrelated individuals from the collaborative study on the genetics of alcoholism. PubMed
Literature searchHumanLiterature search   
15211641HumanLinkage Alcoholism phenotype along with age, gender, and P300 or constraintHill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
16534506HumanLinkage ADSX (number of DSM-IV AD symptoms)Prescott et al. Mol Psychiatry. (2006) Genomewide linkage study in the Irish affected sib pair study of alcohol dependence: evidence for a susceptibility region for symptoms of alcohol dependence on chromosome 4. PubMed
17067344HumanLinkage WDSFS (withdrawal symptoms factor score), ONSET (age at onset of AD), ISENS (initial sensitivity), TOLMX (tolerance/maximum drinking)Kuo et al. Alcohol Clin Exp Res. (2006) Identification of susceptibility loci for alcohol-related traits in the Irish Affected Sib Pair Study of Alcohol Dependence. PubMed
HuGE NavigatorHumanLiterature data mining Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; AlcoholismWei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
11410715MouseMicroarrayWhole brainEthanol sensitivityXu et al. Alcohol Clin Exp Res. (2001) Comparison of global brain gene expression profiles between inbred long-sleep and inbred short-sleep mice by high-density gene array hybridization. PubMed
12805289MouseMicroarray and QTLWhole brainAcute functional tolerance to ethanolTabakoff et al. J Neurosci. (2003) Selective breeding, quantitative trait locus analysis, and gene arrays identify candidate genes for complex drug-related behaviors. PubMed
15002731MouseMicroarrayWhole brainAcute ethanol responseTreadwell et al. Neurochem Res. (2004) Microarray analysis of mouse brain gene expression following acute ethanol treatment. PubMed
15282116MouseMicroarrayStriataAlcohol-nonpreferring, alcohol-preferring, alcohol self-administrationSaito et al. Alcohol. (2004) Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol. PubMed
15668661MouseMicroarrayFetal brainEthanol responseHard et al. J Lab Clin Med. (2005) Gene-expression analysis after alcohol exposure in the developing mouse. PubMed
16465594MouseMicroarray and QTLCerebellumEthanol sensitivityMacLaren et al. Mamm Genome. (2006) Expression profiling identifies novel candidate genes for ethanol sensitivity QTLs. PubMed
16783646MouseMicroarray and QTLWhole brainAlcohol preference, acute functional toleranceSaba et al. Mamm Genome. (2006) Candidate genes and their regulatory elements: alcohol preference and tolerance. PubMed
17295719MouseMicroarrayCultured fetal mouse cortical neuronsEthanol responseWang et al. Alcohol Clin Exp Res. (2007) Regulation of platelet-derived growth factor signaling pathway by ethanol, nicotine, or both in mouse cortical neurons. PubMed
15745951MouseMicroarrayNucleus accumbens, prefrontal cortex, and ventral tegmental areaAcute ethanol responseKerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
16618939MouseMicroarrayWhole brainAlcohol preferenceMulligan et al. Proc Natl Acad Sci U S A. (2006) Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. PubMed
MouseQTLMouseQTL Acute Alcohol Withdrawal, Chronic Alcohol Withdrawal, Alcohol Preference Drinking, Alcohol Stimulated Activity, Alcohol-induced Loss of Righting Reflex, Alcohol AcceptancePARC Alcohol QTLs by Phenotype at Portland Alcohol Research Center.
15597075MouseMicroarray and QTLBrainAcute ethanol withdrawal, Chronic ethanol withdrawal, Ethanol preference drinking, Ethanol-stimulated activityHitzemann et al. Alcohol Clin Exp Res. (2004) On the integration of alcohol-related quantitative trait loci and gene expression analyses. PubMed
11772933RatMicroarrayFrontal cortex and amygdalaEthanol responseRimondini et al FASEB J. (2002) Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol. PubMed
15660665RatMicroarrayHippocampusAlcohol-preferring, alcohol-nonpreferringEdenberg et al. Genes Brain Behav. (2005) Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring rats. PubMed
15846778RatMicroarrayFrontal cortexAlcohol-preferring, alcohol-nonpreferringWorst et al. J Neurosci Res. (2005) Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. PubMed
17451403RatMicroarray and QTLNucleus accumbens, frontal cortex, amygdala, hippocampus, and striatumAlcohol Preference, alcohol-preferring, alcohol-nonpreferringCarr et al. Alcohol Clin Exp Res. (2007) Identification of candidate genes for alcohol preference by expression profiling of congenic rat strains. PubMed
17517326RatMicroarrayNucleus accumbens, amygdala, frontal cortex, caudate-putamen, and hippocampusAlcohol-preferring, alcohol-nonpreferringKimpel et al. Alcohol. (2007) Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions. PubMed
18405950RatMicroarrayNucleus accumbens and amygdalaEthanol self-administration, alcohol-preferringRodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
15028283WormMicroarray Ethanol responseKwon et al. Genomics. (2004) Ethanol-response genes and their regulation analyzed by a microarray and comparative genomic approach in the nematode Caenorhabditis elegans. PubMed
17054780FlyMicroarray Ethanol responseMorozova et al. Genome Biol. (2006) Transcriptional response to alcohol exposure in Drosophila melanogaster. PubMed
17973985FlyMicroarray Ethanol sensitivityMorozova et al. Genome Biol. (2007) Phenotypic and transcriptional response to selection for alcohol sensitivity in Drosophila melanogaster. PubMed