Found 484 literature records

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Entrez ID	Description
2034	"Results confirm that HIF-2alpha is tumor suppressive, and suggest that HIF-1alpha may also be tumor suppressive."
3091	"Results confirm that HIF-2alpha is tumor suppressive, and suggest that HIF-1alpha may also be tumor suppressive."
7157	Relative role of methylator and tumor suppressor pathways in ulcerative colitis-associated colon cancer.
1002	CDH4 as a novel putative tumor suppressor gene epigenetically silenced by promoter hypermethylation in nasopharyngeal carcinoma.
285671	RNF180 is a novel potential tumor suppressor in gastric carcinogenesis.
407039	"Data show that miR-33a has potential tumor suppressor activity, acting through inhibition of Pim-1."
9046	Mutational and expressional analysis of a haploinsufficient tumor suppressor gene DOK2 in gastric and colorectal cancers.
406904	"MiR-1 is a tumor suppressor in thyroid carcinogenesis targeting CCND2, CXCR4, and SDF-1alpha."
9255	Decreased expression of AIMP1 in gastric and colorectal cancer tissues suggests that down-regulation of this protein may be related to inactivation of the tumor suppressor functions of AIMP proteins and might play a role in the development of GC and CRC.
9521	Decreased expression of AIMP3 in gastric and colorectal cancer tissues suggests that down-regulation of this protein may be related to inactivation of the tumor suppressor functions of AIMP proteins and might play a role in the development of GC and CRC.
23221	"RhoBTB2 (DBC2) functions as tumor suppressor via inhibiting proliferation, preventing colony formation and inducing apoptosis in breast cancer cells."
23328	The candidate tumor suppressor SASH1 interacts with the actin cytoskeleton and stimulates cell-matrix adhesion.
27303	"a tumor suppression function for the human RBMS3 gene in esophageal squamous cell carcinoma, acting through c-Myc downregulation, with genetic loss of this gene contributing to poor outcomes in disease"
324	Messing up disorder: how do missense mutations in the tumor suppressor protein APC lead to cancer?
27250	Expression patterns of the tumor suppressor PDCD4 and correlation with ??-catenin expression in gastric cancers.
324	The tumor suppressor adenomatous polyposis coli controls the direction in which a cell extrudes from an epithelium.
103344718	HOTS (H19 Opposite Tumor Suppressor) encodes a tumor growth inhibitor that localizes to the nucleus and nucleolus and that interacts with the human enhancer of rudimentary homolog (ERH) protein.
51247	Paip2 is able to function as a tumor suppressor
7067	The TR/DKK4/Wnt/beta-catenin cascade influences the proliferation and migration of hepatoma cells during the metastasis process and support a tumor suppressor role of the thyroid hormone receptor.
7068	The TR/DKK4/Wnt/beta-catenin cascade influences the proliferation and migration of hepatoma cells during the metastasis process and support a tumor suppressor role of the thyroid hormone receptor.
54778	Arkadia enhances transforming growth factor-beta signaling responses and supports its tumor-suppressing properties in colorectal cancer.
4163	"Mutated in colorectal cancer (Mcc), a candidate tumor suppressor, is dynamically expressed during mouse embryogenesis."
7262	"TSSC3 has a potent tumor suppressor role in osteosarcoma, probably by inhibition of growth and induction of apoptosis via the mitochondrial apoptosis pathway."
2203	epigenetic inactivation of FBP1 is also common in human liver and colon cancer. FBP1 appears to be a functional tumor suppressor involved in the liver and colon carcinogenesis
1029	Tumor suppressor p16INK4a controls oncogenic K-Ras function in human pancreatic cancer cells.
1029	Hypergrowth mTORC1 signals translationally activate the ARF tumor suppressor checkpoint.
116135	Methylation pattern of the putative tumor-suppressor gene LRRC3B promoter in clear cell renal cell carcinomas.
5098	"our data suggest that the PCDH LRES is an important tumour suppressor locus in colorectal cancer, and that PCDHGC3 may be a strong marker and driver for the adenoma-carcinoma transition."
406958	"These results indicate that miR-182 targets the CREB1 gene and suppresses gastric adenocarcinoma cell growth, suggesting that miR-182 shows tumor-suppressive activity in human gastric cancer."
55384	MEG3 noncoding RNA: a tumor suppressor.
55384	MEG3 noncoding RNA: a tumor suppressor. These lines of evidence strongly suggest that MEG3 functions as a novel lncRNA tumor suppressor.
960	"CD44, as expressed by LS174T colon carcinoma cells, functions as a tumor suppressor. When the expression of CD44 is silenced, we see a dramatic increase in metastatic potential"
4494	MT1F is a putative tumor suppressor gene in colon carcinogenesis that is downregulated mainly by loss of heterozygosity in colon cancer tissue
407037	"These findings indicate that miR-320a suppresses the growth of colon cancer cells by directly targeting beta-catenin, suggesting its application in prognosis prediction and cancer treatment."
406997	"miR-378, miR-375, miR-422a and miR-215 play an important role in the colorectal cancer as tumour suppressors"
494324	"miR-378, miR-375, miR-422a and miR-215 play an important role in the colorectal cancer as tumour suppressors"
494327	"miR-378, miR-375, miR-422a and miR-215 play an important role in the colorectal cancer as tumour suppressors"
494334	"miR-378, miR-375, miR-422a and miR-215 play an important role in the colorectal cancer as tumour suppressors"
246	Mice with human 15-LOX-1 expression in colonic epithelial cells were less susceptible than wild-type mice to AOM-induced colonic tumorigenesis. 15-LOX-1 appears to act as a tumor suppressor and an inhibitor of TNF-alpha-iNOS signaling and NF-kappaB activation.
406995	miR-181b may function as a tumor suppressor in gastric adenocarcinoma cells through negative regulation of CREB1
57410	suggested that the interaction of SCYL1BP1/Pirh2 could accelerate Pirh2 degradation through an ubiquitin-dependent pathway. SCYL1BP1 may function as an important tumor suppressor gene in HCC development
574504	miR-502 may function as a potential tumor suppressor and therefore be a novel candidate for developing miR-502-based therapeutic strategies.
1316	miR-181a functions as an oncomir in gastric cancer by repressing the expression of tumor suppressor KLF6.
159989	suggest that CCDC67 is a putative tumor suppressor gene that is silenced in gastric cancers by promoter CpG methylation and that it may play an important role in cell signaling and migration related to tumorigenesis
2273	"FHL1 is a methylation-silenced tumor-suppressor gene on chromosome X in gastrointestinal cancers, and that its silencing contributes to the formation of an epigenetic field for cancerization."
406929	"The miR-138 might be a tumor suppressor in nasopharyngeal carcinoma, which is exerted partially by inhibiting CCND1 expression."
56616	Results demonstrate an essential and apoptosis-independent function of SMAC in tumor suppression and provide new insights into the biology and targeting of colon cancer.
6656	These findings suggest that SOX1 might function as an important tumor suppressor during the development of hepatocellular carcinoma.
406912	a novel molecular mechanism by which MMP13 is up-regulated in cSCCs and indicate that miR-125b plays a tumor suppressive role in cSCC.
1045	"EphA2 activation by ephrin-A1 induces tumor suppressor gene cdx-2 expression which attenuates cell proliferation, tumor growth and thus may be a promising therapeutic target against NSCLC."

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