Found 484 literature records

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Entrez ID	Description
8404	"SPARCL1 functions as a tumor suppressor promoting differentiation possibly via MET, which inhibits the aggressiveness of colorectal cancers"
645811	CCDC154 is a novel osteopetrosis-related gene involved in cell cycle regulation and tumor suppression growth.
442915	"miR-370 may function as a tumor suppressor by targeting FoxM1, and the epigenetic silence of miR-370 thus leads to derepression of FoxM1 expression and consequently contributes to AML development and progression."
406976	miR-199a-5p can regulate CAC1 and function as a tumor suppressor in colorectal cancer.
56999	ADAMTS9 acts as a functional tumor suppressor in gastric cancer through inhibiting oncogenic AKT/mTOR signaling pathway
27253	"PCDH17 acts as a tumour suppressor, exerting its anti-proliferative activity through inducing apoptosis and autophagy, and is frequently silenced in gastric and colorectal cancers."
406940	"miR-148a and miR-152 act as tumor suppressors by targeting IGF-IR and IRS1, and that restoration of miR-148a/152 expression may provide a strategy for therapeutic application to treat BC patients."
406943	"miR-148a and miR-152 act as tumor suppressors by targeting IGF-IR and IRS1, and that restoration of miR-148a/152 expression may provide a strategy for therapeutic application to treat BC patients."
9314	"Kruppel-like factor 4, a tumor suppressor in hepatocellular carcinoma cells reverts epithelial mesenchymal transition by suppressing slug expression."
1036	CDO1 as a novel tumor suppressor gene and a potentially valuable molecular marker for human cancer
2633	results suggested that GBP-1 acts directly as a tumor suppressor in CRC and the loss of GBP-1 expression might indicate tumor evasion from the IFN-gamma-dominated Th1 immune response.
7476	WNT7A gene is inactivated by genetic/epigenetic alterations in clear cell RCC and demonstrates tumor suppressor properties
406906	Results demonstrate that miR-122 functions as a tumor suppressor and plays an important role in inhibiting the tumorigenesis through targeting IGF1.
51339	These findings provided insight into the role of DACT1 as a novel functional tumor suppressor in gastric cancer through inhibiting NF-kappaB signaling pathway.
574453	miR-495 likely functions as a tumor suppressor in acute myeloid leukemia with MLL rearrangements.
407043	MiR-7 is a novel miRNA with tumor suppressive function in colon cancer by targeting oncogenic YY1.
8405	Loss of expression of SPOP gene might play a role in cancer pathogenesis by altering tumor suppressor gene functions of SPOP.
693221	"miR-636 might function as a tumor suppressor miRNA affecting hepatocellular carcinoma (HCC) tumorigenesis via downregulation of Ras, and that ANT2 suppression by shRNA could exert an anticancer effect by restoring miR-636 expression in HCC."
65979	Data indicate that Phactr4 acts as a tumor suppressor that is deleted and mutant in several cancers.
574033	"results demonstrate a novel role for miR-18b as a tumor suppressor in melanoma, identify the MDM2-p53 pathway as a target of miR-18b action, and suggest miR-18b overexpression as a novel strategy to reactivate the p53 pathway in human tumors."
84816	RTN4IP1 has a tumor-suppressive function and may regulate thyroid cancer progression.
407024	miR-29b may function as a tumor suppressor by targeting ABL1 and BCR/ABL1.
407014	MiR-25 may function as a tumor suppressor by targeting Smad7 in colon cancer.
407039	"that miR-33a may be a potent tumor suppressor, which inhibits direct and indirect osteoclastogenesis through repression of PTHrP."
494324	Tumor suppressor miR-375 regulates MYC expression via repression of CIP2A coding sequence through multiple miRNA-mRNA interactions.
285194	"The results suggest that loc285194 is a p53-regulated tumor suppressor, which acts in part through repression of miR-211."
406942	findings show that miR-150 acts as a tumor suppressor through direct repression of multiple oncogenes in MLL-AF9-induced leukemias; miR-150 inhibits MLL-AF9 leukemic cell growth in vitro by induction of apoptosis and blocks the progression of MLL-AF9 leukemias in vivo
406913	Results suggest miR-126 function as a potential tumor suppressor in colon cancer progression and miR-126/RhoA/ROCK may be a novel candidate for developing rational therapeutic strategies.
406934	"MiR-142-3p functions as a tumor suppressor by targeting CD133, ABCG2, and Lgr5 in colon cancer cells"
9429	"MiR-142-3p functions as a tumor suppressor by targeting CD133, ABCG2, and Lgr5 in colon cancer cells"
8651	"SOCS1 gene is a direct target of miR-19a, which functions as an oncogenic miRNA in gastric cancer by repressing the expression of tumor suppressor SOCS1."
55294	Regulation of APC(Cdh1) E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7.
9093	Tid1 acts as a tumor suppressor by inhibiting EGFR signaling through interaction with EGFR/HSP70/HSP90 and enhancing EGFR ubiquitinylation and degradation.
64579	NDST4 gene is a novel candidate tumor suppressor gene in human cancer.
3880	KRT19 is a potential tumor suppressor that negatively regulates Akt signaling through modulation of Egr1 nuclear localization.
25930	PTPN23 is a tumor suppressor and that repression of PTPN23 expression by miR-142-3p plays an important role in the pathogenesis of testicular germ cell tumors.
407011	MicroRNA-23b functions as a tumor suppressor by regulating Zeb1 in bladder cancer.
11107	"Data provide the first causal link between Prdm5 loss and intestinal carcinogenesis, and uncover an extensive and novel PRDM5 target repertoire likely facilitating the tumor-suppressive functions of PRDM5."
4916	our findings suggest NTRK3 is a conditional tumor suppressor gene that is commonly inactivated in colorectal cancer by both epigenetic and genetic mechanisms
123920	CMTM3 is significantly down-regulated in clear cell renal cell carcinoma and exerts remarkable tumor-suppressive functions
56475	"Reprimo expression is normally induced in response to DNA damage, acting as a novel tumor suppressor in gastric cancer; however, Reprimo methylation abrogates its expression and effects"
406988	miR-205 is a tumor suppressor in human breast cancer by post-transcriptional inhibition of HER3 expression.
406937	"this study suggests that miR-145 modulates ovarian cancer growth and invasion by suppressing p70S6K1 and MUC1, functioning as a tumor suppressor."
100126306	miR-888 functions to promote prostate cancer progression and can suppress protein levels of the tumor suppressor genes RBL1 and SMAD4.
7053	"TGM3, a candidate tumor suppressor, contributes to the carcinogenesis and development of human head and neck cancer."
8870	the interference of IER3 with the PI3K/Akt-Fyn pathway represents a novel mechanism of Nrf2 regulation that may get lost in tumors and by which IER3 exerts its stress-adaptive and tumor-suppressive activity.
574408	Data indicate that overexpression of KDM1A partially reversed the tumor suppressive effects of miR-329 in neuroblastoma cells.
6924	TCEB3C is a putative tumor suppressor gene of small intestinal neuroendocrine tumors
338442	GPR109A is a tumor suppressor in mammary gland.
407055	miR-99a functions as a tumor metastasis suppressor in Oral squamous cell carcinoma cells and mutually regulates IGF1R

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