DegronMD - E9PAV3(NACA)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A242T	TCGA-17-Z011	LUAD	TCGA	PQTTPTTT	DEG_SCF_FBW7_1	231:238	Mutation rewiring degron network	0.2222
p.A221V	TCGA-2W-A8YY	CESC	TCGA	PQTTPTTT	DEG_SCF_FBW7_1	231:238	Mutation rewiring degron network	0.0556
p.A221V	DO223732	CESC	ICGC	PQTTPTTT	DEG_SCF_FBW7_1	231:238	Mutation rewiring degron network	0.0556
p.S75W	TCGA-55-A4DF	LUAD	TCGA	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.1111
p.S75W	DO45318	LUAD	ICGC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.1111
p.P136A	TCGA-63-A5MM	LUSC	TCGA	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation rewiring degron network	0.2778
p.P136A	DO219153	LUSC	ICGC	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation rewiring degron network	0.2778
p.S782G	TCGA-74-6577	GBM	TCGA	DSGASAT	DEG_SCF_TRCP1_1	774:780	Mutation rewiring degron network	0.2778
p.R787Q	TCGA-86-8073	LUAD	TCGA	DSGASAT	DEG_SCF_TRCP1_1	774:780	Mutation rewiring degron network	0.1389
p.G88A	TCGA-A2-A04W	BRCA	TCGA	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.3056
p.G88A	DO4787	BRCA	ICGC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.3056
p.R781W	TCGA-A5-A2K5	UCEC	TCGA	DSGASAT	DEG_SCF_TRCP1_1	774:780	Mutation rewiring degron network	0.3056
p.R781W	TCGA-BS-A0UV	UCEC	TCGA	DSGASAT	DEG_SCF_TRCP1_1	774:780	Mutation rewiring degron network	0.3056
p.R781W	TCGA-IB-A6UG	PAAD	TCGA	DSGASAT	DEG_SCF_TRCP1_1	774:780	Mutation rewiring degron network	0.3056
p.G327C	TCGA-AA-3864	COAD	TCGA	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation rewiring degron network	0.1944
p.G327C	DO8490	COAD	ICGC	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation rewiring degron network	0.1944
p.A330V	TCGA-AD-6889	COAD	TCGA	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation rewiring degron network	0.1111
p.A330V	DO8463	COAD	ICGC	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation rewiring degron network	0.1111
p.P81S	TCGA-AX-A0J1	UCEC	TCGA	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.2778
p.P81S	DO41199	UCEC	ICGC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.2778
p.P311H	TCGA-AX-A1CE	UCEC	TCGA	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation altering degron motif	0.7694
p.P311H	DO42280	UCEC	ICGC	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation altering degron motif	0.7694
p.S329G	TCGA-BR-4363	STAD	TCGA	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation rewiring degron network	0.1389
p.S329G	DO38815	STAD	ICGC	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation rewiring degron network	0.1389
p.S316Y	TCGA-BS-A0UF	UCEC	TCGA	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation altering degron motif	0.6009
p.S316Y	DO41488	UCEC	ICGC	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation altering degron motif	0.6009
p.G699A	TCGA-CF-A47X	BLCA	TCGA	TLTTLPLVPTA	DEG_COP1_1	694:704	Mutation altering degron motif	0.754
p.E892Q	TCGA-CV-6961	HNSC	TCGA	PKETPTPS	DEG_SCF_FBW7_1	882:889	Mutation rewiring degron network	0.25
p.E875D	TCGA-CV-6961	HNSC	TCGA	PKETPTPS	DEG_SCF_FBW7_1	882:889	Mutation rewiring degron network	0.1389
p.Q290E	TCGA-CV-7178	HNSC	TCGA	VVTSS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.3056
p.Q290E	TCGA-IR-A3LK	CESC	TCGA	VVTSS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.3056
p.Q290E	DO44299	CESC	ICGC	VVTSS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.3056
p.Q290E	DO14774	HNSC	ICGC	VVTSS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.3056
p.E749K	TCGA-D5-6535	COAD	TCGA	PAGTPPGT	DEG_SCF_FBW7_1	741:748	Mutation rewiring degron network	0.3056
p.P302L	TCGA-D9-A1JX	SKCM	TCGA	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation rewiring degron network	0.1389
p.P302L	DO37711	SKCM	ICGC	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation rewiring degron network	0.1389
p.N732S	TCGA-DF-A2KU	UCEC	TCGA	PAGTPPGT	DEG_SCF_FBW7_1	741:748	Mutation substituting flanking lysine	0.1944
p.E771K	TCGA-DK-A1AC	BLCA	TCGA	DSGASAT	DEG_SCF_TRCP1_1	774:780	Mutation rewiring degron network	0.25
p.S780C	TCGA-DX-AB2E	SARC	TCGA	DSGASAT	DEG_SCF_TRCP1_1	774:780	Mutation altering degron motif	0.7541
p.L283R	TCGA-E6-A1LX	UCEC	TCGA	VVTSS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.2778
p.L283R	DO41020	UCEC	ICGC	VVTSS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.2778
p.P77L	TCGA-EE-A29E	SKCM	TCGA	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.1667
p.P77L	DO37831	SKCM	ICGC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.1667
p.P77L	SIDM00138	Non-Small Cell Lung Carcinoma	GDSC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.1667
p.P295S	TCGA-EE-A2MS	SKCM	TCGA	VVTSS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.1667
p.P295S	DO37567	SKCM	ICGC	VVTSS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.1667
p.P284L	TCGA-EE-A2MS	SKCM	TCGA	VVTSS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.3056
p.P284L	DO37567	SKCM	ICGC	VVTSS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.3056
p.F301V	TCGA-EO-A22X	UCEC	TCGA	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation rewiring degron network	0.1111
p.F301V	DO43907	UCEC	ICGC	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation rewiring degron network	0.1111
p.P302S	TCGA-FR-A3YO	SKCM	TCGA	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation rewiring degron network	0.1389
p.P302S	DO37419	SKCM	ICGC	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation rewiring degron network	0.1389
p.G736E	TCGA-G2-AA3B	BLCA	TCGA	PAGTPPGT	DEG_SCF_FBW7_1	741:748	Mutation rewiring degron network	0.1944
p.S304Y	TCGA-IB-7651	PAAD	TCGA	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation rewiring degron network	0.1944
p.S304Y	TCGA-ND-A4WC	UCS	TCGA	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation rewiring degron network	0.1944
p.S304Y	DO46657	PAAD	ICGC	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation rewiring degron network	0.1944
p.L331F	TCGA-K4-A3WS	BLCA	TCGA	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation rewiring degron network	0.0833
p.L331F	DO480	BLCA	ICGC	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation rewiring degron network	0.0833
p.P693L	TCGA-VQ-A8P2	STAD	TCGA	TLTTLPLVPTA	DEG_COP1_1	694:704	Mutation rewiring degron network	0.3056
p.P693L	SIDM00951	T-Lymphoblastic Leukemia	GDSC	TLTTLPLVPTA	DEG_COP1_1	694:704	Mutation rewiring degron network	0.3056
p.P693L	CTV-1	haematopoietic and lymphoid tissue	COSMIC	TLTTLPLVPTA	DEG_COP1_1	694:704	Mutation rewiring degron network	0.3056
p.P231L	TCGA-W3-A825	SKCM	TCGA	PQTTPTTT	DEG_SCF_FBW7_1	231:238	Mutation altering degron motif	0.6471
p.P231L	DO51272	SKCM	ICGC	PQTTPTTT	DEG_SCF_FBW7_1	231:238	Mutation altering degron motif	0.6471
p.S697F	TCGA-WE-A8K5	SKCM	TCGA	TLTTLPLVPTA	DEG_COP1_1	694:704	Mutation altering degron motif	0.7982
p.I123T	TCGA-ZF-AA4R	BLCA	TCGA	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation rewiring degron network	0.2222
p.I123T	DO219083	BLCA	ICGC	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation rewiring degron network	0.2222
p.G1852A	DO44042	BLCA	ICGC	LAPADEDELLPL	DEG_ODPH_VHL_1	1832:1843	Mutation rewiring degron network	0.0833
p.P712A	DO2401	BRCA	ICGC	TLTTLPLVPTA	DEG_COP1_1	694:704	Mutation rewiring degron network	0.1111
p.A1835V	DO8151	COAD	ICGC	LAPADEDELLPL	DEG_ODPH_VHL_1	1832:1843	Mutation altering degron motif	0.5825
p.P1067R	DO10662	COAD	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation rewiring degron network	0.2222
p.L1841P	DO229010	COCA	ICGC	LAPADEDELLPL	DEG_ODPH_VHL_1	1832:1843	Mutation altering degron motif	0.7582
p.L1841P	DO229016	COCA	ICGC	LAPADEDELLPL	DEG_ODPH_VHL_1	1832:1843	Mutation altering degron motif	0.7582
p.L1841P	DO229003	COCA	ICGC	LAPADEDELLPL	DEG_ODPH_VHL_1	1832:1843	Mutation altering degron motif	0.7582
p.L1841P	DO229005	COCA	ICGC	LAPADEDELLPL	DEG_ODPH_VHL_1	1832:1843	Mutation altering degron motif	0.7582
p.L1841P	DO52365	LUSC	ICGC	LAPADEDELLPL	DEG_ODPH_VHL_1	1832:1843	Mutation altering degron motif	0.7582
p.H1122P	DO229016	COCA	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.2222
p.H1122P	DO229003	COCA	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.2222
p.H1122P	DO23306	LINC	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.2222
p.H1122P	DO227544	PACA	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.2222
p.S1557P	DO228093	EOPC	ICGC	LAPKEALIPPAMTV	DEG_ODPH_VHL_1	1542:1555	Mutation rewiring degron network	0.2778
p.P1846L	DO234305	ESAD	ICGC	LAPADEDELLPL	DEG_ODPH_VHL_1	1832:1843	Mutation rewiring degron network	0.25
p.P1846L	DO51761	STAD	ICGC	LAPADEDELLPL	DEG_ODPH_VHL_1	1832:1843	Mutation rewiring degron network	0.25
p.P1846L	ACH-002222	Leukemia	CCLE	LAPADEDELLPL	DEG_ODPH_VHL_1	1832:1843	Mutation rewiring degron network	0.25
p.P1846L	CTV-1	haematopoietic and lymphoid tissue	COSMIC	LAPADEDELLPL	DEG_ODPH_VHL_1	1832:1843	Mutation rewiring degron network	0.25
p.R97W	DO233854	GACA	ICGC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.0556
p.S307P	DO233869	GACA	ICGC	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation rewiring degron network	0.2778
p.K1560N	DO14566	HNSC	ICGC	LAPKEALIPPAMTV	DEG_ODPH_VHL_1	1542:1555	Mutation substituting flanking lysine	0.3056
p.A1246T	DO44441	HNSC	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1241:1247	Mutation altering degron motif	0.6028
p.P1191S	DO15623	HNSC	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1195:1201	Mutation rewiring degron network	0.2222
p.P1191L	DO15623	HNSC	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1195:1201	Mutation rewiring degron network	0.2222
p.P1191L	DO26444	LUSC	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1195:1201	Mutation rewiring degron network	0.2222
p.P1180L	DO15623	HNSC	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1172:1178	Mutation rewiring degron network	0.2778
p.L85V	DO52109	HNSC	ICGC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation altering degron motif	0.6765
p.P1129Q	DO50458	KIRC	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation altering degron motif	0.7035
p.P1071L	DO227499	LAML	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation rewiring degron network	0.1111
p.L1140P	DO227499	LAML	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.1111
p.L1140P	DO227499	LAML	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1149:1155	Mutation rewiring degron network	0.0833
p.T1059P	DO227499	LAML	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation altering degron motif	0.7031
p.G1170R	DO22237	LGG	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1172:1178	Mutation rewiring degron network	0.2778
p.L1209P	DO228815	LICA	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1195:1201	Mutation rewiring degron network	0.1111
p.L1209P	DO228815	LICA	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.0833
p.T238N	DO228924	LICA	ICGC	PQTTPTTT	DEG_SCF_FBW7_1	231:238	Mutation altering degron motif	0.7055
p.T95N	DO229028	LICA	ICGC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.1111
p.P1828H	DO229022	LICA	ICGC	LAPADEDELLPL	DEG_ODPH_VHL_1	1832:1843	Mutation rewiring degron network	0.2222
p.A221D	DO229022	LICA	ICGC	PQTTPTTT	DEG_SCF_FBW7_1	231:238	Mutation rewiring degron network	0.0556
p.A1698D	DO229041	LICA	ICGC	PESTPIIT	DEG_SCF_FBW7_1	1690:1697	Mutation rewiring degron network	0.3056
p.Q133E	DO229057	LICA	ICGC	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation altering degron motif	0.6744
p.P1145L	DO22851	LIHC	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1149:1155	Mutation rewiring degron network	0.2222
p.I96V	DO52267	LIHC	ICGC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.0833
p.I96V	ACH-000707	Lymphoma	CCLE	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.0833
p.H1122Q	DO23184	LINC	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.2222
p.H1122Q	DO23306	LINC	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.2222
p.S782F	DO50814	LIRI	ICGC	DSGASAT	DEG_SCF_TRCP1_1	774:780	Mutation rewiring degron network	0.2778
p.I73V	DO45277	LIRI	ICGC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.0556
p.L139V	DO48723	LIRI	ICGC	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation rewiring degron network	0.1944
p.R77Q	DO23624	LUAD	ICGC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.1667
p.T1197P	DO224576	LUSC	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1195:1201	Mutation altering degron motif	0.7031
p.L1064P	DO224584	LUSC	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation rewiring degron network	0.3056
p.L1064P	DO227544	PACA	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation rewiring degron network	0.3056
p.L1064P	DO230499	PRAD	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation rewiring degron network	0.3056
p.L1064P	DO230590	PRAD	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation rewiring degron network	0.3056
p.L1064P	DO230512	PRAD	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation rewiring degron network	0.3056
p.L1064P	DO51086	PRAD	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation rewiring degron network	0.3056
p.P1134L	DO52365	LUSC	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.2778
p.P1134L	DO37839	SKCM	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.2778
p.P1134L	ACH-000362	Leukemia	CCLE	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.2778
p.P1134L	ACH-000974	Endometrial/Uterine Cancer	CCLE	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.2778
p.P1134L	LK-2	lung	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.2778
p.P1134L	KMH-2	thyroid	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.2778
p.P1134L	RMG-I	ovary	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.2778
p.P1134L	SNG-M	endometrium	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.2778
p.P1134L	RERF-LC-MS	lung	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.2778
p.P1134L	ECC12	stomach	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.2778
p.P1134L	KS-1	central nervous system	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.2778
p.P1134L	8305C	thyroid	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.2778
p.P1134L	MOLM-13	haematopoietic and lymphoid tissue	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation rewiring degron network	0.2778
p.T1128P	DO231064	LUSC	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation altering degron motif	0.7031
p.T1128P	DO218851	SKCA	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation altering degron motif	0.7031
p.E141D	DO26854	LUSC	ICGC	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation rewiring degron network	0.1389
p.A1498S	DO26806	LUSC	ICGC	VATSS	DEG_SPOP_SBC_1	1484:1488	Mutation rewiring degron network	0.0556
p.T1693M	DO50103	LUSC	ICGC	PESTPIIT	DEG_SCF_FBW7_1	1690:1697	Mutation altering degron motif	0.7423
p.T1693M	DO41638	UCEC	ICGC	PESTPIIT	DEG_SCF_FBW7_1	1690:1697	Mutation altering degron motif	0.7423
p.A1131V	DO27556	LUSC	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1126:1132	Mutation altering degron motif	0.5825
p.D752Y	DO219209	LUSC	ICGC	PAGTPPGT	DEG_SCF_FBW7_1	741:748	Mutation rewiring degron network	0.2222
p.E884D	DO228281	MALY	ICGC	PKETPTPS	DEG_SCF_FBW7_1	882:889	Mutation altering degron motif	0.5647
p.P81L	DO220879	MELA	ICGC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.2778
p.P1060L	DO220886	MELA	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation altering degron motif	0.7582
p.P1053S	DO222494	MELA	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation rewiring degron network	0.2222
p.P1053S	ACH-000304	Skin Cancer	CCLE	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation rewiring degron network	0.2222
p.P1053S	ACH-001239	Skin Cancer	CCLE	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation rewiring degron network	0.2222
p.P1053S	WM-115	skin	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation rewiring degron network	0.2222
p.P1237S	DO222708	MELA	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1241:1247	Mutation rewiring degron network	0.2222
p.P136S	DO222731	MELA	ICGC	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation rewiring degron network	0.2778
p.L278F	DO222837	MELA	ICGC	VVTSS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.1389
p.P1846S	DO232832	NACA	ICGC	LAPADEDELLPL	DEG_ODPH_VHL_1	1832:1843	Mutation rewiring degron network	0.25
p.I128M	DO31789	OV	ICGC	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation altering degron motif	0.7618
p.T1220I	DO46657	PAAD	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation altering degron motif	0.7078
p.S1236P	DO227544	PACA	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1241:1247	Mutation rewiring degron network	0.1944
p.S1236P	ACH-000186	Lung Cancer	CCLE	PTTPAAT	DEG_SCF_FBW7_1	1241:1247	Mutation rewiring degron network	0.1944
p.S1236P	NCI-H2444	lung	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1241:1247	Mutation rewiring degron network	0.1944
p.R97Q	DO224740	PACA	ICGC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.0556
p.T1220P	DO46771	PAEN	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation altering degron motif	0.7031
p.T1174P	DO51953	PRAD	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1172:1178	Mutation altering degron motif	0.7031
p.S874P	DO36556	READ	ICGC	PKETPTPS	DEG_SCF_FBW7_1	882:889	Mutation rewiring degron network	0.1111
p.P896S	DO229465	SKCA	ICGC	PKETPTPS	DEG_SCF_FBW7_1	882:889	Mutation rewiring degron network	0.1389
p.P1047S	DO218900	SKCA	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation rewiring degron network	0.0556
p.S1213P	DO218878	SKCA	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.1944
p.S1213P	SJSA-1	bone	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.1944
p.S1213P	A2780	ovary	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.1944
p.S1213P	NB5	autonomic ganglia	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.1944
p.S1213P	SNU-C1	large intestine	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.1944
p.S1213P	LC-1-sq	lung	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.1944
p.S1213P	SCaBER	urinary tract	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.1944
p.S1213P	NCI-H835	lung	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.1944
p.S1190P	DO218854	SKCA	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1195:1201	Mutation rewiring degron network	0.1944
p.P714L	DO37543	SKCM	ICGC	TLTTLPLVPTA	DEG_COP1_1	694:704	Mutation rewiring degron network	0.0556
p.P685L	DO37567	SKCM	ICGC	TLTTLPLVPTA	DEG_COP1_1	694:704	Mutation rewiring degron network	0.0833
p.P1244L	DO37827	SKCM	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1241:1247	Mutation altering degron motif	0.7582
p.S1557F	DO37823	SKCM	ICGC	LAPKEALIPPAMTV	DEG_ODPH_VHL_1	1542:1555	Mutation rewiring degron network	0.2778
p.P1704L	DO37786	SKCM	ICGC	PESTPIIT	DEG_SCF_FBW7_1	1690:1697	Mutation rewiring degron network	0.1389
p.P731S	DO37758	SKCM	ICGC	PAGTPPGT	DEG_SCF_FBW7_1	741:748	Mutation rewiring degron network	0.0556
p.P1214S	DO37437	SKCM	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.2222
p.P1214S	DO47636	SKCM	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.2222
p.S1158F	DO37432	SKCM	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1149:1155	Mutation rewiring degron network	0.25
p.P888S	DO50298	SKCM	ICGC	PKETPTPS	DEG_SCF_FBW7_1	882:889	Mutation altering degron motif	0.5641
p.A1148V	DO50287	SKCM	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1149:1155	Mutation rewiring degron network	0.3056
p.P1157L	DO50288	SKCM	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1149:1155	Mutation rewiring degron network	0.2778
p.S874F	DO47320	SKCM	ICGC	PKETPTPS	DEG_SCF_FBW7_1	882:889	Mutation rewiring degron network	0.1111
p.P1182S	DO37996	SKCM	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1172:1178	Mutation rewiring degron network	0.2222
p.S1227F	DO37931	SKCM	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.25
p.S1850F	DO51282	SKCM	ICGC	LAPADEDELLPL	DEG_ODPH_VHL_1	1832:1843	Mutation rewiring degron network	0.1389
p.P1065S	DO51257	SKCM	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation rewiring degron network	0.2778
p.P712S	DO51246	SKCM	ICGC	TLTTLPLVPTA	DEG_COP1_1	694:704	Mutation rewiring degron network	0.1111
p.P1149L	DO51234	SKCM	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1149:1155	Mutation altering degron motif	0.6471
p.P1145S	DO38123	SKCM	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1149:1155	Mutation rewiring degron network	0.2222
p.P1175S	DO38123	SKCM	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1172:1178	Mutation altering degron motif	0.6752
p.P1558R	DO50136	STAD	ICGC	LAPKEALIPPAMTV	DEG_ODPH_VHL_1	1542:1555	Mutation rewiring degron network	0.25
p.D752G	DO38723	STAD	ICGC	PAGTPPGT	DEG_SCF_FBW7_1	741:748	Mutation rewiring degron network	0.2222
p.T1211A	DO48044	STAD	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1195:1201	Mutation rewiring degron network	0.0556
p.T1211A	DO48044	STAD	ICGC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.1389
p.I128T	DO38259	STAD	ICGC	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation altering degron motif	0.7078
p.P1478H	DO48175	UCEC	ICGC	VATSS	DEG_SPOP_SBC_1	1484:1488	Mutation rewiring degron network	0.1667
p.L85I	DO43306	UCEC	ICGC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation altering degron motif	0.7174
p.N1885S	DO223286	UCEC	ICGC	TESDSDESVPEL	DEG_COP1_1	1890:1901	Mutation rewiring degron network	0.1944
p.A126V	DO41903	UCEC	ICGC	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation rewiring degron network	0.3056
p.P888H	DO41211	UCEC	ICGC	PKETPTPS	DEG_SCF_FBW7_1	882:889	Mutation altering degron motif	0.6583
p.M1553V	DO43755	UCEC	ICGC	LAPKEALIPPAMTV	DEG_ODPH_VHL_1	1542:1555	Mutation altering degron motif	0.6097
p.S783Y	DO42745	UCEC	ICGC	DSGASAT	DEG_SCF_TRCP1_1	774:780	Mutation rewiring degron network	0.25
p.R86W	DO42713	UCEC	ICGC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation altering degron motif	0.8634
p.R86W	ACH-002222	Leukemia	CCLE	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation altering degron motif	0.8634
p.R86W	CTV-1	haematopoietic and lymphoid tissue	COSMIC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation altering degron motif	0.8634
p.I754S	DO41361	UCEC	ICGC	PAGTPPGT	DEG_SCF_FBW7_1	741:748	Mutation rewiring degron network	0.1667
p.A135V	DO230449	UTCA	ICGC	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation rewiring degron network	0.3056
p.Q873R	SIDM02050	Colorectal Carcinoma	GDSC	PKETPTPS	DEG_SCF_FBW7_1	882:889	Mutation rewiring degron network	0.0833
p.M895V	SIDM01951	Colorectal Carcinoma	GDSC	PKETPTPS	DEG_SCF_FBW7_1	882:889	Mutation rewiring degron network	0.1667
p.G698R	SIDM01016	T-Lymphoblastic Leukemia	GDSC	TLTTLPLVPTA	DEG_COP1_1	694:704	Mutation altering degron motif	0.7568
p.G698R	Jurkat	haematopoietic and lymphoid tissue	COSMIC	TLTTLPLVPTA	DEG_COP1_1	694:704	Mutation altering degron motif	0.7568
p.P131L	SIDM00857	Melanoma	GDSC	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation altering degron motif	0.7582
p.P131L	ACH-000572	Skin Cancer	CCLE	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation altering degron motif	0.7582
p.P131L	G-361	skin	COSMIC	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation altering degron motif	0.7582
p.R787W	SIDM01028	Esophageal Squamous Cell Carcinoma	GDSC	DSGASAT	DEG_SCF_TRCP1_1	774:780	Mutation rewiring degron network	0.1389
p.R787W	KYSE-410	oesophagus	COSMIC	DSGASAT	DEG_SCF_TRCP1_1	774:780	Mutation rewiring degron network	0.1389
p.A764V	SIDM00487	Colorectal Carcinoma	GDSC	DSGASAT	DEG_SCF_TRCP1_1	774:780	Mutation rewiring degron network	0.0556
p.A764V	CCK-81	large intestine	COSMIC	DSGASAT	DEG_SCF_TRCP1_1	774:780	Mutation rewiring degron network	0.0556
p.S279L	SIDM01157	Other Solid Cancers	GDSC	VVTSS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.1667
p.S279L	SW954	vulva	COSMIC	VVTSS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.1667
p.E878Q	SIDM00892	Breast Carcinoma	GDSC	PKETPTPS	DEG_SCF_FBW7_1	882:889	Mutation rewiring degron network	0.2222
p.E878Q	BT-483	breast	COSMIC	PKETPTPS	DEG_SCF_FBW7_1	882:889	Mutation rewiring degron network	0.2222
p.L142R	SIDM00900	Non-Cancerous	GDSC	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation rewiring degron network	0.1111
p.P81H	SIDM00145	T-Lymphoblastic Leukemia	GDSC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.2778
p.P81H	ACH-001127	Leukemia	CCLE	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.2778
p.P81H	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.2778
p.V705I	SIDM00783	Colorectal Carcinoma	GDSC	TLTTLPLVPTA	DEG_COP1_1	694:704	Mutation rewiring degron network	0.3056
p.V705I	HCT-116	large intestine	COSMIC	TLTTLPLVPTA	DEG_COP1_1	694:704	Mutation rewiring degron network	0.3056
p.P77H	SIDM01582	Gastric Carcinoma	GDSC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.1667
p.P77H	ACH-000507	Gastric Cancer	CCLE	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.1667
p.P299R	SIDM01664	Prostate Carcinoma	GDSC	LAPLHQSSFGSVQL	DEG_ODPH_VHL_1	309:322	Mutation rewiring degron network	0.0556
p.P299R	SIDM01664	Prostate Carcinoma	GDSC	VVTSS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.0556
p.P1226L	ACH-000151	Leukemia	CCLE	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.2778
p.P1226L	JM1	haematopoietic and lymphoid tissue	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.2778
p.T1058R	ACH-000281	Pancreatic Cancer	CCLE	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation altering degron motif	0.6765
p.T1058R	KP-2	pancreas	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation altering degron motif	0.6765
p.P1225L	ACH-000464	Brain Cancer	CCLE	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.3056
p.P1225L	CAS-1	central nervous system	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.3056
p.P235L	ACH-000600	Kidney Cancer	CCLE	PQTTPTTT	DEG_SCF_FBW7_1	231:238	Mutation altering degron motif	0.7582
p.T1882R	ACH-000802	Bladder Cancer	CCLE	TESDSDESVPEL	DEG_COP1_1	1890:1901	Mutation rewiring degron network	0.1111
p.T1882R	BFTC-905	urinary tract	COSMIC	TESDSDESVPEL	DEG_COP1_1	1890:1901	Mutation rewiring degron network	0.1111
p.R77W	ACH-000809	Esophageal Cancer	CCLE	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.1667
p.R77W	KYSE-410	oesophagus	COSMIC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.1667
p.K691E	ACH-000891	Lung Cancer	CCLE	TLTTLPLVPTA	DEG_COP1_1	694:704	Mutation substituting flanking lysine	0.3611
p.P1167L	ACH-000918	Leukemia	CCLE	PTTPAAT	DEG_SCF_FBW7_1	1172:1178	Mutation rewiring degron network	0.1944
p.P1167L	MOLT-16	haematopoietic and lymphoid tissue	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1172:1178	Mutation rewiring degron network	0.1944
p.A1246V	ACH-000920	Leukemia	CCLE	PTTPAAT	DEG_SCF_FBW7_1	1241:1247	Mutation altering degron motif	0.5825
p.P1060S	ACH-000925	Lung Cancer	CCLE	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation altering degron motif	0.6752
p.Q136H	ACH-000945	Lung Cancer	CCLE	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation rewiring degron network	0.2778
p.Q136H	NCI-H650	lung	COSMIC	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation rewiring degron network	0.2778
p.S713P	ACH-000989	Colon/Colorectal Cancer	CCLE	TLTTLPLVPTA	DEG_COP1_1	694:704	Mutation rewiring degron network	0.0833
p.S713P	SNU-175	large intestine	COSMIC	TLTTLPLVPTA	DEG_COP1_1	694:704	Mutation rewiring degron network	0.0833
p.G124E	ACH-000995	Leukemia	CCLE	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation rewiring degron network	0.25
p.G124E	Jurkat	haematopoietic and lymphoid tissue	COSMIC	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation rewiring degron network	0.25
p.T89I	ACH-000995	Leukemia	CCLE	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.2778
p.T89I	Jurkat	haematopoietic and lymphoid tissue	COSMIC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.2778
p.G1851R	ACH-000995	Leukemia	CCLE	LAPADEDELLPL	DEG_ODPH_VHL_1	1832:1843	Mutation rewiring degron network	0.1111
p.G1851R	Jurkat	haematopoietic and lymphoid tissue	COSMIC	LAPADEDELLPL	DEG_ODPH_VHL_1	1832:1843	Mutation rewiring degron network	0.1111
p.A1245T	ACH-000995	Leukemia	CCLE	PTTPAAT	DEG_SCF_FBW7_1	1241:1247	Mutation altering degron motif	0.6028
p.L695R	ACH-000996	Endometrial/Uterine Cancer	CCLE	TLTTLPLVPTA	DEG_COP1_1	694:704	Mutation altering degron motif	0.7316
p.A1171V	ACH-000998	Colon/Colorectal Cancer	CCLE	PTTPAAT	DEG_SCF_FBW7_1	1172:1178	Mutation rewiring degron network	0.3056
p.A1171V	CW-2	large intestine	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1172:1178	Mutation rewiring degron network	0.3056
p.P1237T	ACH-001127	Leukemia	CCLE	PTTPAAT	DEG_SCF_FBW7_1	1241:1247	Mutation rewiring degron network	0.2222
p.P1237T	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1241:1247	Mutation rewiring degron network	0.2222
p.P1065L	ACH-001127	Leukemia	CCLE	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation rewiring degron network	0.2778
p.P1065L	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1057:1063	Mutation rewiring degron network	0.2778
p.P886A	ACH-002097	Skin Cancer	CCLE	PKETPTPS	DEG_SCF_FBW7_1	882:889	Mutation altering degron motif	0.7503
p.P886A	CP66-MEL	skin	COSMIC	PKETPTPS	DEG_SCF_FBW7_1	882:889	Mutation altering degron motif	0.7503
p.S705L	ACH-002181	Ovarian Cancer	CCLE	TLTTLPLVPTA	DEG_COP1_1	694:704	Mutation rewiring degron network	0.3056
p.S705L	OVCA420	ovary	COSMIC	TLTTLPLVPTA	DEG_COP1_1	694:704	Mutation rewiring degron network	0.3056
p.T1882M	ACH-002256	Leukemia	CCLE	TESDSDESVPEL	DEG_COP1_1	1890:1901	Mutation rewiring degron network	0.1111
p.T1882M	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	TESDSDESVPEL	DEG_COP1_1	1890:1901	Mutation rewiring degron network	0.1111
p.P1159S	ACH-002256	Leukemia	CCLE	PTTPAAT	DEG_SCF_FBW7_1	1149:1155	Mutation rewiring degron network	0.2222
p.P1159S	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1149:1155	Mutation rewiring degron network	0.2222
p.P1214H	NCI-H835	lung	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.2222
p.P1214H	LC-1-sq	lung	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.2222
p.P1214H	SCaBER	urinary tract	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.2222
p.P1214H	SJSA-1	bone	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.2222
p.P1214H	A2780	ovary	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.2222
p.P1214H	SNU-C1	large intestine	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1218:1224	Mutation rewiring degron network	0.2222
p.P1255L	EB2	haematopoietic and lymphoid tissue	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1241:1247	Mutation rewiring degron network	0.1111
p.P1255L	NCI-H2444	lung	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1241:1247	Mutation rewiring degron network	0.1111
p.P1255L	NCI-H835	lung	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1241:1247	Mutation rewiring degron network	0.1111
p.P1244Q	CTV-1	haematopoietic and lymphoid tissue	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1241:1247	Mutation altering degron motif	0.7035
p.A1833T	LCLC-103H	lung	COSMIC	LAPADEDELLPL	DEG_ODPH_VHL_1	1832:1843	Mutation altering degron motif	0.7139
p.E89Q	BT-483	breast	COSMIC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.2778
p.P1244T	CTV-1	haematopoietic and lymphoid tissue	COSMIC	PTTPAAT	DEG_SCF_FBW7_1	1241:1247	Mutation altering degron motif	0.7031
p.K82N	NALM-6	haematopoietic and lymphoid tissue	COSMIC	PQSSS	DEG_SPOP_SBC_1	83:87	Mutation rewiring degron network	0.3056
p.T1554A	PE/CA-PJ15	upper aerodigestive tract	COSMIC	LAPKEALIPPAMTV	DEG_ODPH_VHL_1	1542:1555	Mutation altering degron motif	0.6028
p.K1537N	OACp4C	oesophagus	COSMIC	LAPKEALIPPAMTV	DEG_ODPH_VHL_1	1542:1555	Mutation substituting flanking lysine	0.3056
p.N129S	ML-1	thyroid	COSMIC	LKGTPSSS	DEG_SCF_FBW7_1	127:134	Mutation altering degron motif	0.7069

DegronMD: protein-targeted degradation, mutation and drug response to degrons

NACA

UniProt ID: E9PAV3

Entrez ID:

Protein name: Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form) (skNAC)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for NACA in