DegronMD - Q6W4X9(MUC6)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G1813R	TCGA-13-1405	OV	TCGA	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.3056
p.G1813R	DO28012	OV	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.3056
p.P1272T	TCGA-17-Z056	LUAD	TCGA	VTPQAT	DEG_SCF_FBW7_1	1278:1283	Mutation rewiring degron network	0.1667
p.A1788S	TCGA-22-5472	LUSC	TCGA	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation rewiring degron network	0.1944
p.A1788S	TCGA-22-5472	LUSC	TCGA	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.3056
p.A1788S	DO27421	LUSC	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation rewiring degron network	0.1944
p.A1788S	DO27421	LUSC	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.3056
p.P1315Q	TCGA-22-5483	LUSC	TCGA	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation rewiring degron network	0.1667
p.P1315Q	DO26614	LUSC	ICGC	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation rewiring degron network	0.1667
p.T2342M	TCGA-4R-AA8I	LIHC	TCGA	LGTPTPT	DEG_SCF_FBW7_1	2338:2344	Mutation altering degron motif	0.6312
p.T2342M	DO49657	LIHC	ICGC	LGTPTPT	DEG_SCF_FBW7_1	2338:2344	Mutation altering degron motif	0.6312
p.T1347I	TCGA-56-6545	LUSC	TCGA	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation rewiring degron network	0.0556
p.T1347I	DO26532	LUSC	ICGC	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation rewiring degron network	0.0556
p.V2046D	TCGA-56-A4BW	LUSC	TCGA	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.3056
p.V2046D	DO45441	LUSC	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.3056
p.S1700A	TCGA-56-A5DS	LUSC	TCGA	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation rewiring degron network	0.1667
p.S1700A	DO45494	LUSC	ICGC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation rewiring degron network	0.1667
p.V1278I	TCGA-85-8351	LUSC	TCGA	VTPQAT	DEG_SCF_FBW7_1	1278:1283	Mutation altering degron motif	0.5965
p.V1278I	TCGA-BR-8361	STAD	TCGA	VTPQAT	DEG_SCF_FBW7_1	1278:1283	Mutation altering degron motif	0.5965
p.V1278I	DO45447	LUSC	ICGC	VTPQAT	DEG_SCF_FBW7_1	1278:1283	Mutation altering degron motif	0.5965
p.V1278I	DO48032	STAD	ICGC	VTPQAT	DEG_SCF_FBW7_1	1278:1283	Mutation altering degron motif	0.5965
p.S1811Y	TCGA-85-8354	LUSC	TCGA	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation altering degron motif	0.712
p.S1811Y	DO45467	LUSC	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation altering degron motif	0.712
p.T1914A	TCGA-85-8355	LUSC	TCGA	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation altering degron motif	0.7139
p.T1914A	DO45488	LUSC	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation altering degron motif	0.7139
p.P1334Q	TCGA-86-8073	LUAD	TCGA	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation altering degron motif	0.7035
p.P1334Q	DO23624	LUAD	ICGC	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation altering degron motif	0.7035
p.T1778N	TCGA-96-A4JK	LUSC	TCGA	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.1944
p.T1778N	DO45442	LUSC	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.1944
p.T1342M	TCGA-A5-A0GH	UCEC	TCGA	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation rewiring degron network	0.1944
p.T1342M	DO43634	UCEC	ICGC	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation rewiring degron network	0.1944
p.S1915A	TCGA-A8-A07O	BRCA	TCGA	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation altering degron motif	0.7588
p.S1915A	DO1277	BRCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation altering degron motif	0.7588
p.A2210T	TCGA-AA-3492	COAD	TCGA	AASTT	DEG_SPOP_SBC_1	2203:2207	Mutation rewiring degron network	0.25
p.A2210T	DO8224	COAD	ICGC	AASTT	DEG_SPOP_SBC_1	2203:2207	Mutation rewiring degron network	0.25
p.P1808S	TCGA-AC-A23H	BRCA	TCGA	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation altering degron motif	0.6752
p.P1808S	DO2401	BRCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation altering degron motif	0.6752
p.S1710F	TCGA-AC-A23H	BRCA	TCGA	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation altering degron motif	0.7982
p.S1710F	TCGA-BS-A0UF	UCEC	TCGA	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation altering degron motif	0.7982
p.S1710F	DO2401	BRCA	ICGC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation altering degron motif	0.7982
p.S1710F	DO41488	UCEC	ICGC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation altering degron motif	0.7982
p.T1411M	TCGA-AC-A23H	BRCA	TCGA	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.1944
p.T1411M	DO2401	BRCA	ICGC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.1944
p.T1411M	DO233762	GACA	ICGC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.1944
p.T1411M	SIDM01303	Esophageal Carcinoma	GDSC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.1944
p.T1411M	SIDM01650	Non-Cancerous	GDSC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.1944
p.H2149Y	TCGA-AC-A6IX	BRCA	TCGA	VGTSS	DEG_SPOP_SBC_1	2159:2163	Mutation rewiring degron network	0.0556
p.H2149Y	DO50030	BRCA	ICGC	VGTSS	DEG_SPOP_SBC_1	2159:2163	Mutation rewiring degron network	0.0556
p.S1346L	TCGA-AG-A002	READ	TCGA	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation rewiring degron network	0.0833
p.S1346L	SIDM01051	Ovarian Carcinoma	GDSC	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation rewiring degron network	0.0833
p.S1346L	ACH-000936	Ovarian Cancer	CCLE	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation rewiring degron network	0.0833
p.S1346L	EFO-27	ovary	COSMIC	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation rewiring degron network	0.0833
p.T1707I	TCGA-AJ-A3EL	UCEC	TCGA	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation altering degron motif	0.5966
p.T1707I	DO41542	UCEC	ICGC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation altering degron motif	0.5966
p.A1499V	TCGA-AP-A1DK	UCEC	TCGA	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.3056
p.A1499V	DO42033	UCEC	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.3056
p.P1449H	TCGA-AX-A1CE	UCEC	TCGA	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation altering degron motif	0.7694
p.P1449H	DO42280	UCEC	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation altering degron motif	0.7694
p.T1330I	TCGA-AX-A2HD	UCEC	TCGA	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation rewiring degron network	0.3056
p.T1330I	TCGA-AX-A2HD	UCEC	TCGA	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation rewiring degron network	0.1944
p.T1330I	DO42608	UCEC	ICGC	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation rewiring degron network	0.3056
p.T1330I	DO42608	UCEC	ICGC	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation rewiring degron network	0.1944
p.A2261T	TCGA-AX-A3FT	UCEC	TCGA	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.1667
p.A2261T	TCGA-CV-5435	HNSC	TCGA	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.1667
p.A2261T	DO14299	HNSC	ICGC	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.1667
p.A2261T	DO40801	UCEC	ICGC	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.1667
p.A2261T	SIDM00412	B-Cell Non-Hodgkin's Lymphoma	GDSC	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.1667
p.A2261T	SIDM01612	Endometrial Carcinoma	GDSC	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.1667
p.A2261T	ACH-000946	Endometrial/Uterine Cancer	CCLE	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.1667
p.A2261T	ACH-001991	Primary	CCLE	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.1667
p.A2261T	WSU-NHL	haematopoietic and lymphoid tissue	COSMIC	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.1667
p.T1318M	TCGA-AZ-6598	COAD	TCGA	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation rewiring degron network	0.25
p.T1318M	DO10276	COAD	ICGC	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation rewiring degron network	0.25
p.S2156W	TCGA-B0-5096	KIRC	TCGA	VGTSS	DEG_SPOP_SBC_1	2159:2163	Mutation rewiring degron network	0.25
p.S2156W	DO19218	KIRC	ICGC	VGTSS	DEG_SPOP_SBC_1	2159:2163	Mutation rewiring degron network	0.25
p.T1317M	TCGA-B5-A3FA	UCEC	TCGA	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation rewiring degron network	0.2222
p.T1317M	DO52402	UCEC	ICGC	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation rewiring degron network	0.2222
p.A2036V	TCGA-BG-A0MT	UCEC	TCGA	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.2778
p.A2036V	DO41698	UCEC	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.2778
p.T1411K	TCGA-BG-A221	UCEC	TCGA	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.1944
p.T1411K	TCGA-CD-A4MI	STAD	TCGA	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.1944
p.T1411K	DO47717	STAD	ICGC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.1944
p.T1411K	DO42384	UCEC	ICGC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.1944
p.T1411S	TCGA-BG-A221	UCEC	TCGA	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.1944
p.T1411S	DO42384	UCEC	ICGC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.1944
p.T1745A	TCGA-BP-4801	KIRC	TCGA	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation altering degron motif	0.7139
p.T1745A	DO18066	KIRC	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation altering degron motif	0.7139
p.P2346H	TCGA-BR-4201	STAD	TCGA	LGTPTPT	DEG_SCF_FBW7_1	2338:2344	Mutation rewiring degron network	0.2778
p.P2346H	DO38707	STAD	ICGC	LGTPTPT	DEG_SCF_FBW7_1	2338:2344	Mutation rewiring degron network	0.2778
p.H1752Y	TCGA-BR-4292	STAD	TCGA	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1944
p.H1752Y	TCGA-BR-4292	STAD	TCGA	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.0833
p.H1752Y	DO38495	STAD	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1944
p.H1752Y	DO38495	STAD	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.0833
p.S1340G	TCGA-BR-8487	STAD	TCGA	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation rewiring degron network	0.25
p.S1340G	DO47867	STAD	ICGC	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation rewiring degron network	0.25
p.S1790N	TCGA-BR-A4QI	STAD	TCGA	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation blocking phosphorylation signal	0.6944
p.S1790N	TCGA-BR-A4QI	STAD	TCGA	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation blocking phosphorylation signal	0.6944
p.S1790N	DO38523	STAD	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation blocking phosphorylation signal	0.6944
p.S1790N	DO38523	STAD	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation blocking phosphorylation signal	0.6944
p.T1804A	TCGA-BS-A0UF	UCEC	TCGA	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation rewiring degron network	0.1944
p.T1804A	TCGA-BS-A0UF	UCEC	TCGA	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.2222
p.T1804A	DO41488	UCEC	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation rewiring degron network	0.1944
p.T1804A	DO41488	UCEC	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.2222
p.S2035F	TCGA-CQ-5333	HNSC	TCGA	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.25
p.S2035F	TCGA-D6-A6EQ	HNSC	TCGA	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.25
p.S2035F	DO14218	HNSC	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.25
p.S2035F	DO52085	HNSC	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.25
p.S1915C	TCGA-CQ-7071	HNSC	TCGA	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation altering degron motif	0.7541
p.S1915C	DO49069	HNSC	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation altering degron motif	0.7541
p.A1277T	TCGA-D3-A2JL	SKCM	TCGA	VTPQAT	DEG_SCF_FBW7_1	1278:1283	Mutation rewiring degron network	0.3056
p.A1277T	DO47278	SKCM	ICGC	VTPQAT	DEG_SCF_FBW7_1	1278:1283	Mutation rewiring degron network	0.3056
p.S1736F	TCGA-D3-A8GB	SKCM	TCGA	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1389
p.S1736F	DO50280	SKCM	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1389
p.S1696T	TCGA-DD-AAC8	LIHC	TCGA	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation rewiring degron network	0.0556
p.S1696T	DO52193	LIHC	ICGC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation rewiring degron network	0.0556
p.Q1322E	TCGA-DK-AA6L	BLCA	TCGA	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation altering degron motif	0.5633
p.Q1322E	DO219002	BLCA	ICGC	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation altering degron motif	0.5633
p.E1760K	TCGA-DX-A7EU	SARC	TCGA	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.3056
p.E1760K	DO45119	LIRI	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.3056
p.E1760K	DO220040	SARC	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.3056
p.P1814H	TCGA-EA-A3HU	CESC	TCGA	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.2778
p.P1814H	DO6320	CESC	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.2778
p.T2251M	TCGA-EA-A439	CESC	TCGA	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation altering degron motif	0.7423
p.T2251M	DO44297	CESC	ICGC	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation altering degron motif	0.7423
p.T2251M	DO233784	GACA	ICGC	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation altering degron motif	0.7423
p.S1323F	TCGA-EA-A439	CESC	TCGA	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation altering degron motif	0.7982
p.S1323F	DO44297	CESC	ICGC	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation altering degron motif	0.7982
p.G1413E	TCGA-EB-A3XC	SKCM	TCGA	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.1389
p.G1413E	DO37579	SKCM	ICGC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.1389
p.T1816P	TCGA-EE-A29B	SKCM	TCGA	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.2222
p.T1816P	DO47255	SKCM	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.2222
p.N1548S	TCGA-EE-A29M	SKCM	TCGA	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation altering degron motif	0.5958
p.N1548S	DO37404	SKCM	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation altering degron motif	0.5958
p.T1529N	TCGA-EE-A2M5	SKCM	TCGA	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation rewiring degron network	0.1667
p.T1529N	TCGA-EE-A2M5	SKCM	TCGA	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.T1529N	DO222423	MELA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation rewiring degron network	0.1667
p.T1529N	DO222423	MELA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.T1529N	DO37425	SKCM	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation rewiring degron network	0.1667
p.T1529N	DO37425	SKCM	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.P1808T	TCGA-EO-A22X	UCEC	TCGA	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation altering degron motif	0.7031
p.P1808T	DO43907	UCEC	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation altering degron motif	0.7031
p.P1781H	TCGA-EO-A3KX	UCEC	TCGA	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.2778
p.P1781H	DO219774	UCEC	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.2778
p.G2044D	TCGA-ER-A193	SKCM	TCGA	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation altering degron motif	0.6087
p.G2044D	DO47368	SKCM	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation altering degron motif	0.6087
p.A1290D	TCGA-F4-6703	COAD	TCGA	VTPQAT	DEG_SCF_FBW7_1	1278:1283	Mutation rewiring degron network	0.1389
p.A1290D	DO9908	COAD	ICGC	VTPQAT	DEG_SCF_FBW7_1	1278:1283	Mutation rewiring degron network	0.1389
p.S1765F	TCGA-FD-A3NA	BLCA	TCGA	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation altering degron motif	0.7982
p.S1765F	DO602	BLCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation altering degron motif	0.7982
p.T1742K	TCGA-FF-A7CR	DLBC	TCGA	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.3056
p.T1742K	DO219894	DLBC	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.3056
p.E1705K	TCGA-FW-A3R5	SKCM	TCGA	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation rewiring degron network	0.0833
p.E1705K	TCGA-FW-A3R5	SKCM	TCGA	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation rewiring degron network	0.3056
p.E1705K	DO37406	SKCM	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation rewiring degron network	0.0833
p.E1705K	DO37406	SKCM	ICGC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation rewiring degron network	0.3056
p.P2213H	TCGA-H4-A2HO	BLCA	TCGA	AASTT	DEG_SPOP_SBC_1	2203:2207	Mutation rewiring degron network	0.1667
p.P2213H	DO494	BLCA	ICGC	AASTT	DEG_SPOP_SBC_1	2203:2207	Mutation rewiring degron network	0.1667
p.I2208F	TCGA-IN-A6RN	STAD	TCGA	AASTT	DEG_SPOP_SBC_1	2203:2207	Mutation rewiring degron network	0.3056
p.I2208F	DO51739	STAD	ICGC	AASTT	DEG_SPOP_SBC_1	2203:2207	Mutation rewiring degron network	0.3056
p.P1814A	TCGA-KQ-A41R	BLCA	TCGA	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.2778
p.P1814A	DO223592	BLCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.2778
p.T1742M	TCGA-SX-A7SL	KIRP	TCGA	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.3056
p.T1742M	DO49783	KIRP	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.3056
p.T1742M	SIDM01278	Colorectal Carcinoma	GDSC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.3056
p.Q1821K	TCGA-VQ-A8PT	STAD	TCGA	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0833
p.Q1821K	DO51776	STAD	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0833
p.T1276M	TCGA-VQ-A91D	STAD	TCGA	VTPQAT	DEG_SCF_FBW7_1	1278:1283	Mutation blocking phosphorylation signal	0.7222
p.T1276M	DO51783	STAD	ICGC	VTPQAT	DEG_SCF_FBW7_1	1278:1283	Mutation blocking phosphorylation signal	0.7222
p.T1276M	SIDM00458	Acute Myeloid Leukemia	GDSC	VTPQAT	DEG_SCF_FBW7_1	1278:1283	Mutation blocking phosphorylation signal	0.7222
p.T1276M	ACH-000751	Leukemia	CCLE	VTPQAT	DEG_SCF_FBW7_1	1278:1283	Mutation blocking phosphorylation signal	0.7222
p.T1276M	OCI-M1	haematopoietic and lymphoid tissue	COSMIC	VTPQAT	DEG_SCF_FBW7_1	1278:1283	Mutation blocking phosphorylation signal	0.7222
p.A2204V	TCGA-VQ-A928	STAD	TCGA	AASTT	DEG_SPOP_SBC_1	2203:2207	Mutation altering degron motif	0.5825
p.A2204V	DO51798	STAD	ICGC	AASTT	DEG_SPOP_SBC_1	2203:2207	Mutation altering degron motif	0.5825
p.A2194T	TCGA-WS-AB45	COAD	TCGA	AASTT	DEG_SPOP_SBC_1	2203:2207	Mutation rewiring degron network	0.0833
p.A2194T	DO51734	COAD	ICGC	AASTT	DEG_SPOP_SBC_1	2203:2207	Mutation rewiring degron network	0.0833
p.A2247V	TCGA-XF-A8HE	BLCA	TCGA	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.2778
p.A2247V	DO49797	BLCA	ICGC	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.2778
p.I2038M	TCGA-ZF-A9RN	BLCA	TCGA	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation altering degron motif	0.6507
p.I2038M	DO219081	BLCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation altering degron motif	0.6507
p.Y1920S	DO48395	BLCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.1111
p.Y1920S	DO48395	BLCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.2222
p.Y1920S	DO48385	BLCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.1111
p.Y1920S	DO48385	BLCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.2222
p.Y1920S	DO48390	BLCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.1111
p.Y1920S	DO48390	BLCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.2222
p.Y1920S	DO48377	BLCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.1111
p.Y1920S	DO48377	BLCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.2222
p.Y1920S	DO48370	BLCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.1111
p.Y1920S	DO48370	BLCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.2222
p.Y1920S	DO48432	BLCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.1111
p.Y1920S	DO48432	BLCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.2222
p.Q1821H	DO48367	BLCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0833
p.Q1821H	DO48370	BLCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0833
p.Q1821H	DO48407	BLCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0833
p.Q1821H	DO224674	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0833
p.Q1821H	DO224786	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0833
p.Q1821H	DO229010	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0833
p.Q1821H	DO229013	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0833
p.Q1821H	DO229016	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0833
p.Q1821H	DO229003	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0833
p.Q1821H	DO229005	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0833
p.T1795I	DO48360	BLCA	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation altering degron motif	0.7078
p.T1807S	DO48360	BLCA	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation rewiring degron network	0.1111
p.T1807S	DO48360	BLCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.3056
p.T1807S	DO222760	COCA	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation rewiring degron network	0.1111
p.T1807S	DO222760	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.3056
p.T1807S	DO222839	COCA	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation rewiring degron network	0.1111
p.T1807S	DO222839	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.3056
p.T1807S	DO50980	LAML	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation rewiring degron network	0.1111
p.T1807S	DO50980	LAML	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.3056
p.T1807S	DO51021	LAML	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation rewiring degron network	0.1111
p.T1807S	DO51021	LAML	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.3056
p.T1807S	DO51025	LAML	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation rewiring degron network	0.1111
p.T1807S	DO51025	LAML	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.3056
p.T1807S	DO52372	LUSC	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation rewiring degron network	0.1111
p.T1807S	DO52372	LUSC	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.3056
p.H1513Q	DO48419	BLCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.H1513Q	DO223532	CLLE	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.H1513Q	DO224645	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.H1513Q	DO222790	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.H1513Q	DO229013	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.H1513Q	DO229208	THCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.H1513Q	DO229216	THCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.H1513Q	DO229218	THCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.H1513Q	DO229240	THCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.T1822A	DO48417	BLCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0556
p.T1822A	DO48407	BLCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0556
p.T1822A	DO224786	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0556
p.T1822A	DO229010	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0556
p.T1822A	DO229013	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0556
p.T1822A	DO229016	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0556
p.T1822A	DO229003	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0556
p.T1822A	DO229005	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0556
p.Q1735H	DO228483	BRCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1111
p.Q1735H	DO224772	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1111
p.Q1735H	DO224808	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1111
p.Q1735H	DO222894	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1111
p.Q1735H	DO222829	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1111
p.Q1735H	DO229003	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1111
p.Q1735H	DO229346	LAML	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1111
p.Q1735H	DO50986	LAML	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1111
p.Q1735H	DO52369	LUSC	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1111
p.Q1735H	DO229467	SKCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1111
p.P1716S	DO228483	BRCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation altering degron motif	0.6752
p.P1716S	DO224820	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation altering degron motif	0.6752
p.P1716S	DO222762	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation altering degron motif	0.6752
p.P1716S	DO222793	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation altering degron motif	0.6752
p.P1716S	DO222894	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation altering degron motif	0.6752
p.P1716S	DO222829	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation altering degron motif	0.6752
p.P1716S	DO229346	LAML	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation altering degron motif	0.6752
p.P1716S	DO50986	LAML	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation altering degron motif	0.6752
p.P1716S	DO51031	LAML	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation altering degron motif	0.6752
p.P1716S	DO228390	LICA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation altering degron motif	0.6752
p.P1716S	DO228589	LICA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation altering degron motif	0.6752
p.P1716S	DO52389	LUSC	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation altering degron motif	0.6752
p.H1750R	DO228483	BRCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.25
p.H1750R	DO224685	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.25
p.H1750R	DO224808	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.25
p.H1750R	DO224817	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.25
p.H1750R	DO222894	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.25
p.H1750R	DO229013	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.25
p.H1750R	DO229003	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.25
p.H1750R	DO229346	LAML	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.25
p.H1750R	DO51031	LAML	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.25
p.H1750R	DO52389	LUSC	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.25
p.R2352W	DO230334	COCA	ICGC	LGTPTPT	DEG_SCF_FBW7_1	2338:2344	Mutation rewiring degron network	0.1111
p.A2256T	DO227745	COCA	ICGC	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.3056
p.L2052V	DO224668	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1389
p.L2052V	DO224726	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1389
p.P1906L	DO224668	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.1667
p.P1906L	DO229010	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.1667
p.P1906L	DO229016	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.1667
p.P1906L	DO229003	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.1667
p.P1906L	DO229005	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.1667
p.P2049L	DO224661	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.2222
p.P2049L	DO224616	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.2222
p.P2049L	DO222709	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.2222
p.P2049L	DO222849	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.2222
p.P2049L	DO229010	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.2222
p.P2049L	DO229013	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.2222
p.P2049L	DO229016	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.2222
p.P2049L	DO229003	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.2222
p.P2049L	DO229005	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.2222
p.P2049L	DO229211	THCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.2222
p.T2030A	DO224671	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1111
p.T2030A	DO222884	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1111
p.T2030A	DO229013	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1111
p.T2030A	DO229016	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1111
p.T2030A	DO229003	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1111
p.T2030A	DO229005	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1111
p.T2030A	DO229213	THCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1111
p.T2030A	DO229250	THCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1111
p.A2033S	DO224671	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1944
p.A2033S	DO222884	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1944
p.A2033S	DO229013	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1944
p.A2033S	DO229016	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1944
p.A2033S	DO229003	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1944
p.A2033S	DO229173	THCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1944
p.G1777D	DO224685	COCA	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.1667
p.P1501L	DO224685	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation altering degron motif	0.6471
p.P1501L	DO229013	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation altering degron motif	0.6471
p.P1501L	DO229003	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation altering degron motif	0.6471
p.S1708P	DO224616	COCA	ICGC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation altering degron motif	0.6752
p.S1708P	DO222746	COCA	ICGC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation altering degron motif	0.6752
p.S1708P	DO222835	COCA	ICGC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation altering degron motif	0.6752
p.A1706V	DO224620	COCA	ICGC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation altering degron motif	0.5825
p.A1706V	DO222746	COCA	ICGC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation altering degron motif	0.5825
p.A1706V	DO222835	COCA	ICGC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation altering degron motif	0.5825
p.A1492T	DO224761	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1111
p.A1492D	DO224761	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1111
p.A1492D	CTV-1	haematopoietic and lymphoid tissue	COSMIC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1111
p.I1502M	DO224775	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation altering degron motif	0.6507
p.I1502M	DO222765	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation altering degron motif	0.6507
p.I1502M	DO222869	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation altering degron motif	0.6507
p.I1502M	DO229010	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation altering degron motif	0.6507
p.I1502M	DO229013	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation altering degron motif	0.6507
p.I1502M	DO229016	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation altering degron motif	0.6507
p.I1502M	DO229003	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation altering degron motif	0.6507
p.S1768T	DO224775	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.25
p.S1768T	DO222480	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.25
p.S1768T	DO229010	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.25
p.S1768T	DO229016	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.25
p.S1768T	DO52338	LUSC	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.25
p.H1513P	DO224775	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.H1513P	DO224801	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.H1513P	DO222790	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.H1513P	DO229013	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.F1516I	DO224772	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.0833
p.F1516I	DO222476	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.0833
p.S1517N	DO224701	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.0556
p.R1737P	DO224726	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1667
p.R1737P	DO224735	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1667
p.R1737P	DO224801	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1667
p.R1737P	DO222782	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1667
p.A2054V	DO224731	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.0833
p.A2054V	DO229010	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.0833
p.A2054V	DO229013	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.0833
p.A2054V	DO229016	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.0833
p.A2054V	DO229003	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.0833
p.A2054V	DO229005	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.0833
p.H1697Q	DO224739	COCA	ICGC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation rewiring degron network	0.0833
p.A1512V	DO224739	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1944
p.A1512V	DO222471	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1944
p.A1512V	DO229016	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1944
p.G1508R	DO224735	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.3056
p.G1508R	DO229013	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.3056
p.G1508R	DO229003	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.3056
p.P1539T	DO224735	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation altering degron motif	0.7031
p.P1539T	DO224735	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.7031
p.P1539T	DO229010	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation altering degron motif	0.7031
p.P1539T	DO229010	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.7031
p.P1539T	DO229013	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation altering degron motif	0.7031
p.P1539T	DO229013	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.7031
p.P1539T	DO229016	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation altering degron motif	0.7031
p.P1539T	DO229016	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.7031
p.P1539T	DO229003	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation altering degron motif	0.7031
p.P1539T	DO229003	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.7031
p.P1539T	DO229005	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation altering degron motif	0.7031
p.P1539T	DO229005	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.7031
p.T1540N	DO224735	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation altering degron motif	0.5944
p.T1540N	DO224735	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.5944
p.T1540N	DO224757	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation altering degron motif	0.5944
p.T1540N	DO224757	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.5944
p.T1540N	DO229010	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation altering degron motif	0.5944
p.T1540N	DO229010	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.5944
p.T1540N	DO229013	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation altering degron motif	0.5944
p.T1540N	DO229013	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.5944
p.T1540N	DO229016	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation altering degron motif	0.5944
p.T1540N	DO229016	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.5944
p.T1540N	DO229003	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation altering degron motif	0.5944
p.T1540N	DO229003	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.5944
p.T1540N	DO229005	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation altering degron motif	0.5944
p.T1540N	DO229005	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.5944
p.G1946D	DO224744	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.0556
p.H2029R	DO224744	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.0833
p.S1736A	DO224744	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1389
p.T2028P	DO224744	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.0556
p.A1743G	DO224801	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation altering degron motif	0.754
p.M1726I	DO224801	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation rewiring degron network	0.1389
p.Q1735P	DO224801	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1111
p.H1758Y	DO224801	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.25
p.H1758Y	DO229016	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.25
p.H1758Y	DO229003	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.25
p.H1758Y	DO229211	THCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.25
p.R1737G	DO224801	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1667
p.T1922I	DO224817	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.1667
p.T1922I	DO224817	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.1667
p.T1922I	DO224817	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.0556
p.T1922I	DO222800	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.1667
p.T1922I	DO222800	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.1667
p.T1922I	DO222800	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.0556
p.E1760A	DO222471	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.3056
p.E1760A	DO222703	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.3056
p.V1447I	DO222585	COCA	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.2778
p.V1447I	DO222840	COCA	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.2778
p.G1494R	DO222590	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.G1494R	DO220877	MELA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.H1497Y	DO222590	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.25
p.S1268L	DO222543	COCA	ICGC	VTPQAT	DEG_SCF_FBW7_1	1278:1283	Mutation rewiring degron network	0.0556
p.H1773P	DO222540	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.1111
p.H1773P	DO222540	COCA	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.0556
p.H1773P	DO222741	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.1111
p.H1773P	DO222741	COCA	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.0556
p.H1773P	DO222770	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.1111
p.H1773P	DO222770	COCA	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.0556
p.H1773P	DO222866	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.1111
p.H1773P	DO222866	COCA	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.0556
p.H1773P	DO222894	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.1111
p.H1773P	DO222894	COCA	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.0556
p.H1773P	DO229010	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.1111
p.H1773P	DO229010	COCA	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.0556
p.H1773P	DO229013	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.1111
p.H1773P	DO229013	COCA	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.0556
p.H1773P	DO229016	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.1111
p.H1773P	DO229016	COCA	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.0556
p.H1773P	DO229003	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.1111
p.H1773P	DO229003	COCA	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.0556
p.H1773P	DO229005	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.1111
p.H1773P	DO229005	COCA	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.0556
p.R1779G	DO222741	COCA	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.2222
p.R1779G	DO222866	COCA	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.2222
p.R1779G	DO222884	COCA	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.2222
p.R1779G	DO222894	COCA	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.2222
p.R1779G	DO229010	COCA	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.2222
p.R1779G	DO229016	COCA	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.2222
p.A1704P	DO222746	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation rewiring degron network	0.0556
p.A1704P	DO222746	COCA	ICGC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation rewiring degron network	0.2778
p.A1704P	DO222835	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation rewiring degron network	0.0556
p.A1704P	DO222835	COCA	ICGC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation rewiring degron network	0.2778
p.A1704P	DO229016	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation rewiring degron network	0.0556
p.A1704P	DO229016	COCA	ICGC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation rewiring degron network	0.2778
p.A1704P	DO52338	LUSC	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation rewiring degron network	0.0556
p.A1704P	DO52338	LUSC	ICGC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation rewiring degron network	0.2778
p.T1544M	DO222765	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation rewiring degron network	0.2778
p.T1544M	DO222765	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.3056
p.T1544M	DO222765	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.3056
p.T1911M	DO222785	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.3056
p.T1911M	DO222793	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.3056
p.T1911M	DO222866	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.3056
p.T1911M	DO222826	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.3056
p.T1911M	DO229016	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.3056
p.T1911M	DO229005	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.3056
p.T1911M	DO51006	LAML	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.3056
p.T1911M	DO52364	LUSC	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.3056
p.T1911M	DO52359	LUSC	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.3056
p.S1763P	DO222798	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation altering degron motif	0.6752
p.S1763P	DO229010	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation altering degron motif	0.6752
p.S1763P	DO229016	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation altering degron motif	0.6752
p.S1763P	DO229003	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation altering degron motif	0.6752
p.S1763P	DO229005	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation altering degron motif	0.6752
p.S1763P	DO50981	LAML	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation altering degron motif	0.6752
p.G1813A	DO222737	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.3056
p.P1794T	DO222866	COCA	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation altering degron motif	0.5919
p.P1794T	DO229010	COCA	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation altering degron motif	0.5919
p.P1794T	DO229013	COCA	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation altering degron motif	0.5919
p.P1794T	DO229016	COCA	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation altering degron motif	0.5919
p.P1794T	DO229003	COCA	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation altering degron motif	0.5919
p.P1794T	DO229005	COCA	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation altering degron motif	0.5919
p.P1794T	DO50980	LAML	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation altering degron motif	0.5919
p.P1794T	DO52357	LUSC	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation altering degron motif	0.5919
p.L2241I	DO222884	COCA	ICGC	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.1111
p.K1491M	DO222894	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation substituting flanking lysine	0.1944
p.K1491M	DO229013	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation substituting flanking lysine	0.1944
p.K1491M	DO229003	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation substituting flanking lysine	0.1944
p.R1555G	DO222894	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.1944
p.R1555G	DO229010	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.1944
p.R1555G	DO229013	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.1944
p.R1555G	DO229016	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.1944
p.R1555G	DO229003	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.1944
p.R1555G	DO229005	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.1944
p.R1555G	DO233074	GACA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.1944
p.R1555G	DO51040	LAML	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.1944
p.R1555G	DO52389	LUSC	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.1944
p.R1555G	DO229234	THCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.1944
p.S1768N	DO222894	COCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.25
p.E1440Q	DO222800	COCA	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.0833
p.E1440Q	DO222846	COCA	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.0833
p.E1440Q	DO229010	COCA	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.0833
p.E1440Q	DO229013	COCA	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.0833
p.E1440Q	DO229016	COCA	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.0833
p.E1440Q	DO229003	COCA	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.0833
p.E1440Q	DO229005	COCA	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.0833
p.E1440Q	DO52670	MALY	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.0833
p.T1461I	DO222816	COCA	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.1111
p.H1942P	DO229010	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.1389
p.H1942P	DO229010	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.1667
p.H1942P	DO229013	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.1389
p.H1942P	DO229013	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.1667
p.H1942P	DO229016	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.1389
p.H1942P	DO229016	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.1667
p.H1942P	DO229003	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.1389
p.H1942P	DO229003	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.1667
p.H1942P	DO229005	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.1389
p.H1942P	DO229005	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.1667
p.R1553G	DO229010	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.25
p.R1553G	DO229010	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.R1553G	DO229013	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.25
p.R1553G	DO229013	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.R1553G	DO229016	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.25
p.R1553G	DO229016	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.R1553G	DO229003	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.25
p.R1553G	DO229003	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.R1553G	DO229005	COCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.25
p.R1553G	DO229005	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.R1553G	DO233074	GACA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.25
p.R1553G	DO233074	GACA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.R1553G	DO51040	LAML	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.25
p.R1553G	DO51040	LAML	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.R1553G	DO51028	LAML	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.25
p.R1553G	DO51028	LAML	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.R1553G	DO51004	LAML	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.25
p.R1553G	DO51004	LAML	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.R1553G	DO52377	LUSC	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.25
p.R1553G	DO52377	LUSC	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.R1553G	DO52391	LUSC	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.25
p.R1553G	DO52391	LUSC	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.R1553G	DO52389	LUSC	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.25
p.R1553G	DO52389	LUSC	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.R1553G	DO229180	THCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.25
p.R1553G	DO229180	THCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.R1553G	DO229199	THCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.25
p.R1553G	DO229199	THCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.R1553G	DO229234	THCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.25
p.R1553G	DO229234	THCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.R1553G	DO229248	THCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.25
p.R1553G	DO229248	THCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.V1537I	DO229010	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation altering degron motif	0.5965
p.V1537I	DO229013	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation altering degron motif	0.5965
p.V1537I	DO229016	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation altering degron motif	0.5965
p.V1537I	DO229003	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation altering degron motif	0.5965
p.V1537I	DO229005	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation altering degron motif	0.5965
p.H1528P	DO229010	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation rewiring degron network	0.1389
p.H1528P	DO229013	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation rewiring degron network	0.1389
p.H1528P	DO229016	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation rewiring degron network	0.1389
p.H1528P	DO229003	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation rewiring degron network	0.1389
p.H1528P	DO229005	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation rewiring degron network	0.1389
p.N1937T	DO229010	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.2778
p.N1937T	DO229010	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.3056
p.N1937T	DO229013	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.2778
p.N1937T	DO229013	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.3056
p.N1937T	DO229003	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.2778
p.N1937T	DO229003	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.3056
p.N1937T	DO229268	THCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.2778
p.N1937T	DO229268	THCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.3056
p.P1504A	DO229010	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation altering degron motif	0.7503
p.P1504A	DO229013	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation altering degron motif	0.7503
p.P1504A	DO229016	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation altering degron motif	0.7503
p.P1504A	DO229003	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation altering degron motif	0.7503
p.P1504A	DO229005	COCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation altering degron motif	0.7503
p.P1504A	DO223143	ESCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation altering degron motif	0.7503
p.T1806S	DO229010	COCA	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation rewiring degron network	0.1389
p.T1806S	DO229010	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.2778
p.T1806S	DO229013	COCA	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation rewiring degron network	0.1389
p.T1806S	DO229013	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.2778
p.T1806S	DO229016	COCA	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation rewiring degron network	0.1389
p.T1806S	DO229016	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.2778
p.T1806S	DO229003	COCA	ICGC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation rewiring degron network	0.1389
p.T1806S	DO229003	COCA	ICGC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.2778
p.P1919H	DO229010	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.0833
p.P1919H	DO229010	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.25
p.P1919H	DO229013	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.0833
p.P1919H	DO229013	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.25
p.P1919H	DO229016	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.0833
p.P1919H	DO229016	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.25
p.P1919H	DO229003	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.0833
p.P1919H	DO229003	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.25
p.P1919H	DO229005	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.0833
p.P1919H	DO229005	COCA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.25
p.P1919H	DO52379	LUSC	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.0833
p.P1919H	DO52379	LUSC	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.25
p.P1919H	DO52345	LUSC	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.0833
p.P1919H	DO52345	LUSC	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.25
p.P1919H	DO52388	LUSC	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.0833
p.P1919H	DO52388	LUSC	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.25
p.P1919H	DO52383	LUSC	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.0833
p.P1919H	DO52383	LUSC	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.25
p.K1941N	DO229010	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation substituting flanking lysine	0.2778
p.K1941N	DO229010	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation substituting flanking lysine	0.3056
p.K1941N	DO229013	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation substituting flanking lysine	0.2778
p.K1941N	DO229013	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation substituting flanking lysine	0.3056
p.K1941N	DO229003	COCA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation substituting flanking lysine	0.2778
p.K1941N	DO229003	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation substituting flanking lysine	0.3056
p.V2046I	DO229010	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.3056
p.V2046I	DO229013	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.3056
p.V2046I	DO229016	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.3056
p.V2046I	DO229003	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.3056
p.V2046I	DO229005	COCA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.3056
p.P1449S	DO229013	COCA	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation altering degron motif	0.6752
p.P1449S	DO229016	COCA	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation altering degron motif	0.6752
p.P1449S	DO229003	COCA	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation altering degron motif	0.6752
p.P1449S	DO229005	COCA	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation altering degron motif	0.6752
p.P1449S	DO51019	LAML	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation altering degron motif	0.6752
p.P1449S	DO52373	LUSC	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation altering degron motif	0.6752
p.P1449S	DO52363	LUSC	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation altering degron motif	0.6752
p.P1449S	DO52355	LUSC	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation altering degron motif	0.6752
p.T1776I	DO229016	COCA	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation rewiring degron network	0.1389
p.S1319A	DO234213	ESAD	ICGC	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation rewiring degron network	0.2778
p.Q1322H	DO234213	ESAD	ICGC	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation altering degron motif	0.647
p.A1512S	DO223143	ESCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1944
p.Q1511P	DO223143	ESCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.2222
p.P1504L	DO223143	ESCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation altering degron motif	0.7582
p.T2245S	DO223097	ESCA	ICGC	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.2222
p.R1326W	DO218693	GACA	ICGC	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation rewiring degron network	0.1944
p.R1326W	DO218693	GACA	ICGC	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation rewiring degron network	0.3056
p.R1326W	DO233272	GACA	ICGC	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation rewiring degron network	0.1944
p.R1326W	DO233272	GACA	ICGC	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation rewiring degron network	0.3056
p.S2336F	DO233103	GACA	ICGC	LGTPTPT	DEG_SCF_FBW7_1	2338:2344	Mutation rewiring degron network	0.2778
p.S2250C	DO233101	GACA	ICGC	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation altering degron motif	0.643
p.P2334L	DO233764	GACA	ICGC	LGTPTPT	DEG_SCF_FBW7_1	2338:2344	Mutation rewiring degron network	0.2222
p.A1412V	DO233865	GACA	ICGC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.1667
p.A1412V	SIDM01016	T-Lymphoblastic Leukemia	GDSC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.1667
p.A1412V	SIDM01263	T-Lymphoblastic Leukemia	GDSC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.1667
p.A1412V	Jurkat	haematopoietic and lymphoid tissue	COSMIC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.1667
p.T2041M	DO233864	GACA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation altering degron motif	0.7423
p.T2041M	DO35442	PACA	ICGC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation altering degron motif	0.7423
p.T2041M	HEC-1	endometrium	COSMIC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation altering degron motif	0.7423
p.A1743T	DO233935	GACA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation altering degron motif	0.7139
p.A1743T	SIDM00933	Breast Carcinoma	GDSC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation altering degron motif	0.7139
p.A1743T	SIDM01090	Colorectal Carcinoma	GDSC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation altering degron motif	0.7139
p.A1743T	SIDM01116	Non-Small Cell Lung Carcinoma	GDSC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation altering degron motif	0.7139
p.A1743T	SIDM01117	Small Cell Lung Carcinoma	GDSC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation altering degron motif	0.7139
p.A1743T	SIDM00971	Breast Carcinoma	GDSC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation altering degron motif	0.7139
p.A1743T	SIDM00493	Other Solid Cancers	GDSC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation altering degron motif	0.7139
p.A1743T	SIDM00254	Neuroblastoma	GDSC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation altering degron motif	0.7139
p.A1743T	SIDM00875	Breast Carcinoma	GDSC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation altering degron motif	0.7139
p.A1743T	SIDM01147	Gastric Carcinoma	GDSC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation altering degron motif	0.7139
p.A1743T	SIDM00956	Esophageal Squamous Cell Carcinoma	GDSC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation altering degron motif	0.7139
p.A1743T	SIDM00721	Small Cell Lung Carcinoma	GDSC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation altering degron motif	0.7139
p.A1743T	SIDM01173	Rhabdomyosarcoma	GDSC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation altering degron motif	0.7139
p.S1551R	DO233941	GACA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation rewiring degron network	0.0833
p.S1551R	DO233941	GACA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.3056
p.S1551R	DO233941	GACA	ICGC	PTSTT	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.1111
p.T1786S	DO233903	GACA	ICGC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation altering degron motif	0.6005
p.T1786S	NCI-H661	lung	COSMIC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation altering degron motif	0.6005
p.T1786S	ML-1	thyroid	COSMIC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation altering degron motif	0.6005
p.I2246N	DO228562	LICA	ICGC	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.25
p.I2246N	DO228807	LICA	ICGC	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.25
p.P1725L	DO50970	LICA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation rewiring degron network	0.1667
p.T1496I	DO23260	LINC	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.2222
p.T1496I	DO23424	LINC	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.2222
p.H1513L	DO23178	LINC	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.H1513L	DO229208	THCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.H1513L	DO229218	THCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.H1513L	DO229232	THCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.H1513L	DO229240	THCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.1667
p.T1715A	DO45299	LIRI	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation altering degron motif	0.7139
p.H1404Q	DO224544	LUSC	ICGC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation altering degron motif	0.647
p.H1404Q	DO231014	LUSC	ICGC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation altering degron motif	0.647
p.T1556I	DO231114	LUSC	ICGC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.1667
p.P1771S	DO231165	LUSC	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.1667
p.P1771S	SIDM00262	Ewing's Sarcoma	GDSC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.1667
p.P1771S	ACH-002107	Bone Cancer	CCLE	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.1667
p.P1771S	ES6	bone	COSMIC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.1667
p.E1440D	DO52670	MALY	ICGC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.0833
p.G1269R	DO220882	MELA	ICGC	VTPQAT	DEG_SCF_FBW7_1	1278:1283	Mutation rewiring degron network	0.0833
p.E1536K	DO220903	MELA	ICGC	PEVTPTST	DEG_SCF_FBW7_1	1535:1542	Mutation altering degron motif	0.591
p.S1905F	DO220907	MELA	ICGC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.1389
p.S1734N	DO232052	ORCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.0833
p.P1718S	DO51483	PACA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation altering degron motif	0.5641
p.S2163Y	DO224642	PACA	ICGC	VGTSS	DEG_SPOP_SBC_1	2159:2163	Mutation altering degron motif	0.712
p.I1502V	DO232565	PBCA	ICGC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation altering degron motif	0.5965
p.T1753I	DO232681	PBCA	ICGC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.1667
p.T1753I	DO232681	PBCA	ICGC	VTSTS	DEG_SPOP_SBC_1	1761:1765	Mutation rewiring degron network	0.1111
p.T1723P	DO229453	SKCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation rewiring degron network	0.2222
p.N1717T	DO218908	SKCA	ICGC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation altering degron motif	0.5944
p.T1402P	DO218842	SKCA	ICGC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation altering degron motif	0.7031
p.T1402P	MLMA	haematopoietic and lymphoid tissue	COSMIC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation altering degron motif	0.7031
p.S1408P	DO218842	SKCA	ICGC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.2778
p.T1333P	DO229506	SKCA	ICGC	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation altering degron motif	0.7031
p.S1458R	SIDM01965	Esophageal Carcinoma	GDSC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.1944
p.T1822S	SIDM00331	B-Lymphoblastic Leukemia	GDSC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0556
p.T1822S	SIDM00995	Other Solid Cancers	GDSC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0556
p.T1822S	SIDM00816	Kidney Carcinoma	GDSC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.0556
p.H1702Q	SIDM01068	Non-Small Cell Lung Carcinoma	GDSC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation rewiring degron network	0.2222
p.H1702Q	SIDM00753	Squamous Cell Lung Carcinoma	GDSC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation rewiring degron network	0.2222
p.H1702Q	SIDM01613	Colorectal Carcinoma	GDSC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation rewiring degron network	0.2222
p.H1702Q	HCC-78	lung	COSMIC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation rewiring degron network	0.2222
p.H1702Q	NCI-H2023	lung	COSMIC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation rewiring degron network	0.2222
p.S2244G	SIDM01016	T-Lymphoblastic Leukemia	GDSC	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.1944
p.S2244G	SIDM01263	T-Lymphoblastic Leukemia	GDSC	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.1944
p.S2244G	Jurkat	haematopoietic and lymphoid tissue	COSMIC	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.1944
p.R1326Q	SIDM00545	Melanoma	GDSC	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation rewiring degron network	0.1944
p.R1326Q	SIDM00545	Melanoma	GDSC	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation rewiring degron network	0.3056
p.R1326Q	ACH-000987	Skin Cancer	CCLE	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation rewiring degron network	0.1944
p.R1326Q	ACH-000987	Skin Cancer	CCLE	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation rewiring degron network	0.3056
p.R1326Q	Mewo	skin	COSMIC	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation rewiring degron network	0.1944
p.R1326Q	Mewo	skin	COSMIC	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation rewiring degron network	0.3056
p.S1699Y	SIDM00572	Gastric Carcinoma	GDSC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation rewiring degron network	0.1389
p.S1699Y	NUGC-3	stomach	COSMIC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation rewiring degron network	0.1389
p.V1447A	SIDM00611	Kidney Carcinoma	GDSC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.2778
p.V1447A	SIDM00465	Ovarian Carcinoma	GDSC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.2778
p.V1447A	SIDM00457	Plasma Cell Myeloma	GDSC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.2778
p.V1447A	ACH-000024	Myeloma	CCLE	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.2778
p.V1447A	ACH-000684	Kidney Cancer	CCLE	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.2778
p.V1447A	ACH-002183	Ovarian Cancer	CCLE	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.2778
p.V1447A	OPM-2	haematopoietic and lymphoid tissue	COSMIC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.2778
p.V1447A	KMRC-1	kidney	COSMIC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.2778
p.V1447A	OVMIU	ovary	COSMIC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.2778
p.T2030I	SIDM00967	Ovarian Carcinoma	GDSC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1111
p.T2030I	OVCA420	ovary	COSMIC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1111
p.S1810C	SIDM01878	Non-Cancerous	GDSC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation altering degron motif	0.7541
p.S1810C	SIDM00778	Colorectal Carcinoma	GDSC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation altering degron motif	0.7541
p.S1810C	NCI-H747	large intestine	COSMIC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation altering degron motif	0.7541
p.L1918I	SIDM00789	Colorectal Carcinoma	GDSC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.0556
p.L1918I	SIDM00789	Colorectal Carcinoma	GDSC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.2778
p.L1918I	HCT-15	large intestine	COSMIC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.0556
p.L1918I	HCT-15	large intestine	COSMIC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.2778
p.T1399A	SIDM00789	Colorectal Carcinoma	GDSC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.3056
p.T1399A	ACH-000997	Colon/Colorectal Cancer	CCLE	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.3056
p.T1399A	ACH-001061	Colon/Colorectal Cancer	CCLE	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.3056
p.T1399A	HCT-15	large intestine	COSMIC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.3056
p.S1915F	SIDM00630	Breast Carcinoma	GDSC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation altering degron motif	0.7982
p.S1915F	MDA-MB-415	breast	COSMIC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation altering degron motif	0.7982
p.T1498K	SIDM01078	Small Cell Lung Carcinoma	GDSC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.2778
p.T1498K	SHP-77	lung	COSMIC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation rewiring degron network	0.2778
p.S1934Y	SIDM00475	Ovarian Carcinoma	GDSC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation altering degron motif	0.6009
p.S1934Y	SIDM00475	Ovarian Carcinoma	GDSC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation altering degron motif	0.712
p.S1934Y	ACH-000091	Ovarian Cancer	CCLE	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation altering degron motif	0.6009
p.S1934Y	ACH-000091	Ovarian Cancer	CCLE	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation altering degron motif	0.712
p.S1934Y	OV-56	ovary	COSMIC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation altering degron motif	0.6009
p.S1934Y	OV-56	ovary	COSMIC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation altering degron motif	0.712
p.T1556N	SIDM00350	Head and Neck Carcinoma	GDSC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.1667
p.T1556N	SIDM00018	Acute Myeloid Leukemia	GDSC	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.1667
p.T1556N	ACH-000498	Leukemia	CCLE	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.1667
p.T1556N	ACH-001641	Head and Neck Cancer	CCLE	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.1667
p.T1556N	ACH-002046	Endometrial/Uterine Cancer	CCLE	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.1667
p.T1556N	ACH-002065	Sarcoma	CCLE	ITPNPT	DEG_SCF_FBW7_1	1545:1550	Mutation rewiring degron network	0.1667
p.T1715I	SIDM00719	Small Cell Lung Carcinoma	GDSC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation altering degron motif	0.7078
p.T1715I	NCI-H345	lung	COSMIC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation altering degron motif	0.7078
p.H1750N	SIDM00492	Glioblastoma	GDSC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.25
p.V2166M	SIDM00282	Colorectal Carcinoma	GDSC	VGTSS	DEG_SPOP_SBC_1	2159:2163	Mutation rewiring degron network	0.25
p.V2166M	ACH-000998	Colon/Colorectal Cancer	CCLE	VGTSS	DEG_SPOP_SBC_1	2159:2163	Mutation rewiring degron network	0.25
p.V2166M	CW-2	large intestine	COSMIC	VGTSS	DEG_SPOP_SBC_1	2159:2163	Mutation rewiring degron network	0.25
p.P1344S	SIDM01263	T-Lymphoblastic Leukemia	GDSC	LPTPATS	DEG_SCF_FBW7_1	1331:1337	Mutation rewiring degron network	0.1389
p.T1393R	SIDM00694	Other Solid Cancers	GDSC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.1389
p.P1272R	SIDM00878	Breast Carcinoma	GDSC	VTPQAT	DEG_SCF_FBW7_1	1278:1283	Mutation rewiring degron network	0.1667
p.P1272R	SIDM01710	Squamous Cell Lung Carcinoma	GDSC	VTPQAT	DEG_SCF_FBW7_1	1278:1283	Mutation rewiring degron network	0.1667
p.S1451Y	SIDM00151	Ovarian Carcinoma	GDSC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation altering degron motif	0.712
p.S1451Y	IGROV-1	ovary	COSMIC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation altering degron motif	0.712
p.A1783S	SIDM01118	Small Cell Lung Carcinoma	GDSC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation altering degron motif	0.7588
p.A1783S	NCI-H740	lung	COSMIC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation altering degron motif	0.7588
p.T1742A	SIDM00251	Gastric Carcinoma	GDSC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation rewiring degron network	0.3056
p.S1710C	SIDM01146	Gastric Carcinoma	GDSC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation altering degron motif	0.7541
p.S1710C	NCI-SNU-1	stomach	COSMIC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation altering degron motif	0.7541
p.T2051M	SIDM00254	Neuroblastoma	GDSC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1667
p.T2051M	NB5	autonomic ganglia	COSMIC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1667
p.T2051M	NCI-H250	lung	COSMIC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1667
p.T2051M	NCI-H810	lung	COSMIC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1667
p.T2051M	NCI-H748	lung	COSMIC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation rewiring degron network	0.1667
p.L1443F	SIDM00254	Neuroblastoma	GDSC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.1667
p.L1443F	ACH-002283	Neuroblastoma	CCLE	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.1667
p.L1443F	NB5	autonomic ganglia	COSMIC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.1667
p.T1945K	SIDM00121	T-Lymphoblastic Leukemia	GDSC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.0556
p.T1945K	SIDM00121	T-Lymphoblastic Leukemia	GDSC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.0833
p.T1945K	CCRF-CEM	haematopoietic and lymphoid tissue	COSMIC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation rewiring degron network	0.0556
p.T1945K	CCRF-CEM	haematopoietic and lymphoid tissue	COSMIC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.0833
p.T1747K	SIDM00665	Gastric Carcinoma	GDSC	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation altering degron motif	0.7306
p.T1747K	ACH-000616	Gastric Cancer	CCLE	AKTST	DEG_SPOP_SBC_1	1743:1747	Mutation altering degron motif	0.7306
p.A2168T	SIDM00988	Kidney Carcinoma	GDSC	VGTSS	DEG_SPOP_SBC_1	2159:2163	Mutation rewiring degron network	0.1944
p.A2168T	ACH-000792	Kidney Cancer	CCLE	VGTSS	DEG_SPOP_SBC_1	2159:2163	Mutation rewiring degron network	0.1944
p.A2168T	BFTC-909	kidney	COSMIC	VGTSS	DEG_SPOP_SBC_1	2159:2163	Mutation rewiring degron network	0.1944
p.S1908L	SIDM00097	Breast Carcinoma	GDSC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation blocking phosphorylation signal	0.6667
p.S1908L	T47D	breast	COSMIC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation blocking phosphorylation signal	0.6667
p.R2209K	SIDM00138	Non-Small Cell Lung Carcinoma	GDSC	AASTT	DEG_SPOP_SBC_1	2203:2207	Mutation rewiring degron network	0.2778
p.R2209K	ACH-000900	Lung Cancer	CCLE	AASTT	DEG_SPOP_SBC_1	2203:2207	Mutation rewiring degron network	0.2778
p.R2209K	NCI-H23	lung	COSMIC	AASTT	DEG_SPOP_SBC_1	2203:2207	Mutation rewiring degron network	0.2778
p.Q1904K	SIDM00743	Non-Small Cell Lung Carcinoma	GDSC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.1111
p.Q1904K	NCI-H1666	lung	COSMIC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.1111
p.S1903R	SIDM00743	Non-Small Cell Lung Carcinoma	GDSC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.0833
p.S1903R	NCI-H1666	lung	COSMIC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.0833
p.P1803H	SIDM00980	Gastric Carcinoma	GDSC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation rewiring degron network	0.2222
p.P1803H	SIDM00980	Gastric Carcinoma	GDSC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.1944
p.G1413R	SIDM01398	Melanoma	GDSC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.1389
p.G2339R	SIDM01664	Prostate Carcinoma	GDSC	LGTPTPT	DEG_SCF_FBW7_1	2338:2344	Mutation altering degron motif	0.6457
p.G2339R	SIDM01347	Ovarian Carcinoma	GDSC	LGTPTPT	DEG_SCF_FBW7_1	2338:2344	Mutation altering degron motif	0.6457
p.A2242V	SIDM01710	Squamous Cell Lung Carcinoma	GDSC	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.1389
p.A2242V	ACH-000797	Non-Cancerous	CCLE	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation rewiring degron network	0.1389
p.P1716R	SIDM01391	Neuroblastoma	GDSC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation altering degron motif	0.7512
p.T1312P	ACH-000846	Head and Neck Cancer	CCLE	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation rewiring degron network	0.0833
p.T1312P	ACH-000979	Prostate Cancer	CCLE	AQSTT	DEG_SPOP_SBC_1	1321:1325	Mutation rewiring degron network	0.0833
p.S1787L	ACH-000998	Colon/Colorectal Cancer	CCLE	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation altering degron motif	0.7667
p.S1787L	CW-2	large intestine	COSMIC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation altering degron motif	0.7667
p.T1399P	ACH-000999	Colon/Colorectal Cancer	CCLE	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.3056
p.T1399P	SNU-1040	large intestine	COSMIC	PQTPHTT	DEG_SCF_FBW7_1	1400:1406	Mutation rewiring degron network	0.3056
p.P2249L	ACH-001685	Lymphoma	CCLE	PSTPRTT	DEG_SCF_FBW7_1	2249:2255	Mutation altering degron motif	0.6471
p.P1449R	CAMA-1	breast	COSMIC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation altering degron motif	0.7512
p.E1929A	EW-18	bone	COSMIC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation altering degron motif	0.659
p.E1929A	ML-1	thyroid	COSMIC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation altering degron motif	0.659
p.E1929A	BxPC-3	pancreas	COSMIC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation altering degron motif	0.659
p.E1929A	CAPAN-1	pancreas	COSMIC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation altering degron motif	0.659
p.E1929A	ETK-1	biliary tract	COSMIC	PEVTPTST	DEG_SCF_FBW7_1	1928:1935	Mutation altering degron motif	0.659
p.A1817T	SW872	soft tissue	COSMIC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.1944
p.H2039P	KE-37	haematopoietic and lymphoid tissue	COSMIC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation altering degron motif	0.6583
p.H2039P	SW982	soft tissue	COSMIC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation altering degron motif	0.6583
p.H2039P	OV-56	ovary	COSMIC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation altering degron motif	0.6583
p.H2039P	GAMG	central nervous system	COSMIC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation altering degron motif	0.6583
p.H2039P	SW1990	pancreas	COSMIC	IHSTPTGT	DEG_SCF_FBW7_1	2038:2045	Mutation altering degron motif	0.6583
p.S1458C	T98G	central nervous system	COSMIC	PFSTS	DEG_SPOP_SBC_1	1449:1453	Mutation rewiring degron network	0.1944
p.G1946C	SNU-C5	large intestine	COSMIC	PTSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.0556
p.S1917P	RCC-ER	kidney	COSMIC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.3056
p.S1917P	COR-L105	lung	COSMIC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.3056
p.S1905A	NCI-H1092	lung	COSMIC	AKTST	DEG_SPOP_SBC_1	1912:1916	Mutation rewiring degron network	0.1389
p.G1813D	NAMALWA	haematopoietic and lymphoid tissue	COSMIC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.3056
p.G1813D	HCC1569	breast	COSMIC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.3056
p.G1813D	SK-GT-2	stomach	COSMIC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.3056
p.N1713T	BE2-M17	autonomic ganglia	COSMIC	ITPNPT	DEG_SCF_FBW7_1	1714:1719	Mutation rewiring degron network	0.3056
p.N1713T	BE2-M17	autonomic ganglia	COSMIC	ATSTS	DEG_SPOP_SBC_1	1706:1710	Mutation rewiring degron network	0.25
p.S1507R	A172	central nervous system	COSMIC	PPITPTTS	DEG_SCF_FBW7_1	1500:1507	Mutation altering degron motif	0.7427
p.T1785N	NCC010	kidney	COSMIC	AHTTS	DEG_SPOP_SBC_1	1783:1787	Mutation altering degron motif	0.7055
p.P1802S	SW837	large intestine	COSMIC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation rewiring degron network	0.25
p.P1802S	SW837	large intestine	COSMIC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.1667
p.H1800R	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	LPTPFTT	DEG_SCF_FBW7_1	1793:1799	Mutation rewiring degron network	0.3056
p.H1800R	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	PISST	DEG_SPOP_SBC_1	1808:1812	Mutation rewiring degron network	0.1111

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MUC6

UniProt ID: Q6W4X9

Entrez ID: 4588

Protein name: Mucin-6 (MUC-6) (Gastric mucin-6)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MUC6 in