Logo
Home Search BLAST Integration Document Link Support Citation

Dataset Description
  • Dataset Name: HuGE Navigator
  • Species: Human
  • Method: Literature data mining
  • No. of Genes: 65
  • Phenotype: Alcohol-Induced Disorders
  • Publication: Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
  • Dataset Summary: HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.

    Gene list of this dataset (65 genes)
    Page: 1 2 list all   
    GeneIDSymbolNameGenetic locationPhenotypeNo. of Support Publications
    1636ACEangiotensin I converting enzyme (peptidyl-dipeptidase A) 117q23.3Alcohol-Induced Disorders3
    125ADH1Balcohol dehydrogenase 1B (class I), beta polypeptide4q21-q23Alcohol-Induced Disorders21
    126ADH1Calcohol dehydrogenase 1C (class I), gamma polypeptide4q21-q23Alcohol-Induced Disorders15
    127ADH4alcohol dehydrogenase 4 (class II), pi polypeptide4q21-q24|4q22Alcohol-Induced Disorders1
    183AGTangiotensinogen (serpin peptidase inhibitor, clade A, member 8)1q42-q43Alcohol-Induced Disorders1
    185AGTR1angiotensin II receptor, type 13q21-q25Alcohol-Induced Disorders1
    217ALDH2aldehyde dehydrogenase 2 family (mitochondrial)12q24.2Alcohol-Induced Disorders20
    348APOEapolipoprotein E19q13.2Alcohol-Induced Disorders4
    847CATcatalase11p13Alcohol-Induced Disorders1
    885CCKcholecystokinin3p22-p21.3Alcohol-Induced Disorders1
    886CCKARcholecystokinin A receptor4p15.1-p15.2Alcohol-Induced Disorders1
    887CCKBRcholecystokinin B receptor11p15.4Alcohol-Induced Disorders1
    6352CCL5chemokine (C-C motif) ligand 517q11.2-q12Alcohol-Induced Disorders1
    1231CCR2chemokine (C-C motif) receptor 23p21.31Alcohol-Induced Disorders1
    1234CCR5chemokine (C-C motif) receptor 53p21.31Alcohol-Induced Disorders1
    929CD14CD14 molecule5q22-q32|5q31.1Alcohol-Induced Disorders5
    1056CELcarboxyl ester lipase (bile salt-stimulated lipase)9q34.3Alcohol-Induced Disorders1
    1080CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)7q31.2Alcohol-Induced Disorders6
    1268CNR1cannabinoid receptor 1 (brain)6q14-q15Alcohol-Induced Disorders1
    1312COMTcatechol-O-methyltransferase22q11.21-q11.23|22q11.21Alcohol-Induced Disorders1
    1493CTLA4cytotoxic T-lymphocyte-associated protein 42q33Alcohol-Induced Disorders2
    11330CTRCchymotrypsin C (caldecrin)1p36.21Alcohol-Induced Disorders1
    6387CXCL12chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)10q11.1Alcohol-Induced Disorders1
    1543CYP1A1cytochrome P450, family 1, subfamily A, polypeptide 115q22-q24Alcohol-Induced Disorders1
    1571CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 110q24.3-qterAlcohol-Induced Disorders18
    1621DBHdopamine beta-hydroxylase (dopamine beta-monooxygenase)9q34Alcohol-Induced Disorders2
    1743DLSTdihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)14q24.3Alcohol-Induced Disorders1
    1813DRD2dopamine receptor D211q23Alcohol-Induced Disorders4
    1814DRD3dopamine receptor D33q13.3Alcohol-Induced Disorders1
    2562GABRB3gamma-aminobutyric acid (GABA) A receptor, beta 315q11.2-q12Alcohol-Induced Disorders1
    2899GRIK3glutamate receptor, ionotropic, kainate 31p34-p33Alcohol-Induced Disorders1
    2902GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 19q34.3Alcohol-Induced Disorders1
    2904GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B12p12Alcohol-Induced Disorders1
    2917GRM7glutamate receptor, metabotropic 73p26.1-p25.1Alcohol-Induced Disorders1
    2918GRM8glutamate receptor, metabotropic 87q31.3-q32.1Alcohol-Induced Disorders1
    2938GSTA1glutathione S-transferase A16p12.1Alcohol-Induced Disorders1
    2944GSTM1glutathione S-transferase M11p13.3Alcohol-Induced Disorders6
    2947GSTM3glutathione S-transferase M3 (brain)1p13.3Alcohol-Induced Disorders1
    2950GSTP1glutathione S-transferase pi11q13Alcohol-Induced Disorders4
    2952GSTT1glutathione S-transferase theta 122q11.23Alcohol-Induced Disorders5
    3077HFEhemochromatosis6p21.3Alcohol-Induced Disorders6
    3458IFNGinterferon, gamma12q14Alcohol-Induced Disorders1
    3586IL10interleukin 101q31-q32Alcohol-Induced Disorders5
    3552IL1Ainterleukin 1, alpha2q14Alcohol-Induced Disorders1
    3553IL1Binterleukin 1, beta2q14Alcohol-Induced Disorders1
    3557IL1RNinterleukin 1 receptor antagonist2q14.2Alcohol-Induced Disorders2
    3569IL6interleukin 6 (interferon, beta 2)7p21Alcohol-Induced Disorders1
    3576IL8interleukin 84q13-q21Alcohol-Induced Disorders1
    3856KRT8keratin 812q13Alcohol-Induced Disorders1
    4524MTHFR5,10-methylenetetrahydrofolate reductase (NADPH)1p36.3Alcohol-Induced Disorders3
    Page: 1 2 list all