DegronMD

Uniprot ID: P03372

Source protein: Estrogen receptor

Source gene: ESR1

Class: DEG_SPOP_SBC_1

Location: 571:575

E3 ligase: SPOP

DEGRON score: 0.9845

ASA_SCORE: 73.78

COIL: 0.897

CONS_SCORE: 0.5173

DSS_SCORE: 0.4867

HELIX: 0.0388

FCONS_SCORE: 1.1591

RIG_SCORE: 0.6066

Degron related mutations and impact score

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.S576L	TCGA-A5-A0G2	UCEC	TCGA	AGSTS	DEG_SPOP_SBC_1	0.75
p.S576L	DO41235	UCEC	ICGC	AGSTS	DEG_SPOP_SBC_1	0.75
p.T585M	TCGA-AA-A022	COAD	TCGA	AGSTS	DEG_SPOP_SBC_1	0.0556
p.T585M	DO10647	COAD	ICGC	AGSTS	DEG_SPOP_SBC_1	0.0556
p.S575L	TCGA-EE-A29M	SKCM	TCGA	AGSTS	DEG_SPOP_SBC_1	0.7667
p.S575L	DO37404	SKCM	ICGC	AGSTS	DEG_SPOP_SBC_1	0.7667
p.K581T	TCGA-EO-A22X	UCEC	TCGA	AGSTS	DEG_SPOP_SBC_1	0.2778
p.K581T	DO43907	UCEC	ICGC	AGSTS	DEG_SPOP_SBC_1	0.2778
p.T563M	TCGA-KK-A8I6	PRAD	TCGA	AGSTS	DEG_SPOP_SBC_1	0.1111
p.T563M	DO35350	PACA	ICGC	AGSTS	DEG_SPOP_SBC_1	0.1111
p.T563M	DO219317	PRAD	ICGC	AGSTS	DEG_SPOP_SBC_1	0.1111
p.A569T	SIDM01062	Breast Carcinoma	GDSC	AGSTS	DEG_SPOP_SBC_1	0.2778
p.A569T	HDQ-P1	breast	COSMIC	AGSTS	DEG_SPOP_SBC_1	0.2778

Drug responses associated with ESR1 mutations

Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
SIDM01062	BRCA\|breast	p.W143* (No)	GDSC	Tamoxifen	75.0638
SIDM01062	BRCA\|breast	p.W143* (No)	GDSC	Fulvestrant	41.8853
SIDM01062	BRCA\|breast	p.W143* (No)	GDSC	Tamoxifen	47.839
SIDM01062	BRCA\|breast	p.W143* (No)	GDSC	Fulvestrant	39.852
SIDM01062	BRCA\|breast	p.W143* (No)	GDSC	GDC0810	184.82
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.E181A (No)	GDSC	Tamoxifen	127.6389
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.E181A (No)	GDSC	Fulvestrant	17.6384
SIDM01181	LIHC\|liver	p.D230fs*21 (No)	GDSC	Tamoxifen	34.0823
SIDM01181	LIHC\|liver	p.D230fs*21 (No)	GDSC	Fulvestrant	12.9497
SIDM01181	LIHC\|liver	p.D230fs*21 (No)	GDSC	Tamoxifen	12.996
SIDM01181	LIHC\|liver	p.D230fs*21 (No)	GDSC	Fulvestrant	19.437
SIDM01181	LIHC\|liver	p.D230fs*21 (No)	GDSC	GDC0810	292.94
SIDM00509	SCLC\|lung_small_cell_carcinoma	p.L2* (No)	GDSC	Tamoxifen	70.522
SIDM00509	SCLC\|lung_small_cell_carcinoma	p.L2* (No)	GDSC	Fulvestrant	14.547
SIDM00509	SCLC\|lung_small_cell_carcinoma	p.L2* (No)	GDSC	GDC0810	93.118
SIDM00951	LAML\|acute_myeloid_leukaemia	p.C7Y (No)	GDSC	Tamoxifen	24.9852
SIDM00951	LAML\|acute_myeloid_leukaemia	p.C7Y (No)	GDSC	Fulvestrant	74.2194
SIDM00951	LAML\|acute_myeloid_leukaemia	p.C7Y (No)	GDSC	Tamoxifen	13.947
SIDM00951	LAML\|acute_myeloid_leukaemia	p.C7Y (No)	GDSC	Fulvestrant	6.3655
SIDM00951	LAML\|acute_myeloid_leukaemia	p.C7Y (No)	GDSC	GDC0810	55.395
SIDM00959	LAML\|acute_myeloid_leukaemia	p.K370N (No)	GDSC	Tamoxifen	14.0867
SIDM00959	LAML\|acute_myeloid_leukaemia	p.K370N (No)	GDSC	Fulvestrant	62.8114
SIDM00859	DLBC\|B_cell_lymphoma	p.D426G (No)	GDSC	Tamoxifen	34.4872
SIDM00859	DLBC\|B_cell_lymphoma	p.D426G (No)	GDSC	Fulvestrant	40.4235
SIDM00617	LIHC\|liver	p.P134Q (No)	GDSC	Tamoxifen	44.1001
SIDM00617	LIHC\|liver	p.P134Q (No)	GDSC	Fulvestrant	42.3271
SIDM00617	LIHC\|liver	p.P134Q (No)	GDSC	Tamoxifen	33.787
SIDM00617	LIHC\|liver	p.P134Q (No)	GDSC	Fulvestrant	35.395
SIDM00617	LIHC\|liver	p.P134Q (No)	GDSC	GDC0810	206.31
SIDM00781	COREAD\|large_intestine	p.G276D (No)	GDSC	Tamoxifen	105.4569
SIDM00781	COREAD\|large_intestine	p.G276D (No)	GDSC	Fulvestrant	73.0915
SIDM00781	COREAD\|large_intestine	p.G276D (No)	GDSC	Tamoxifen	97.479
SIDM00781	COREAD\|large_intestine	p.G276D (No)	GDSC	Fulvestrant	89.429
SIDM00781	COREAD\|large_intestine	p.G276D (No)	GDSC	GDC0810	287.19
SIDM00781	COREAD\|large_intestine	p.R151H (No)	GDSC	Tamoxifen	105.4569
SIDM00781	COREAD\|large_intestine	p.R151H (No)	GDSC	Fulvestrant	73.0915
SIDM00781	COREAD\|large_intestine	p.R151H (No)	GDSC	Tamoxifen	97.479
SIDM00781	COREAD\|large_intestine	p.R151H (No)	GDSC	Fulvestrant	89.429
SIDM00781	COREAD\|large_intestine	p.R151H (No)	GDSC	GDC0810	287.19
SIDM00980	STAD\|stomach	p.K299N (No)	GDSC	Tamoxifen	38.8557
SIDM00980	STAD\|stomach	p.K299N (No)	GDSC	Fulvestrant	15.1845
SIDM00980	STAD\|stomach	p.K299N (No)	GDSC	Tamoxifen	21.928
SIDM00980	STAD\|stomach	p.K299N (No)	GDSC	Fulvestrant	26.778
SIDM00980	STAD\|stomach	p.K299N (No)	GDSC	GDC0810	103.63
SIDM00220	OV\|ovary	p.V392I (No)	GDSC	Tamoxifen	35.3496
SIDM00220	OV\|ovary	p.V392I (No)	GDSC	Fulvestrant	29.681
SIDM00220	OV\|ovary	p.V392I (No)	GDSC	Tamoxifen	36.338
SIDM00220	OV\|ovary	p.V392I (No)	GDSC	Fulvestrant	12.329
SIDM00220	OV\|ovary	p.V392I (No)	GDSC	GDC0810	126.24
SIDM00003	SKCM\|melanoma	p.D321N (No)	GDSC	Tamoxifen	107.6549
SIDM00003	SKCM\|melanoma	p.D321N (No)	GDSC	Fulvestrant	58.3221
SIDM00003	SKCM\|melanoma	p.D321N (No)	GDSC	Tamoxifen	11.735
SIDM00003	SKCM\|melanoma	p.D321N (No)	GDSC	Fulvestrant	24.406
SIDM00003	SKCM\|melanoma	p.D321N (No)	GDSC	GDC0810	255.13
SIDM01125	UNCLASSIFIED\|lung_NSCLC_not_specified	p.I5V (No)	GDSC	Fulvestrant	16.7273
SIDM00946	ALL\|T_cell_leukemia	p.L35fs*51 (No)	GDSC	Tamoxifen	5.2111
SIDM00946	ALL\|T_cell_leukemia	p.L35fs*51 (No)	GDSC	Fulvestrant	9.5494
SIDM00946	ALL\|T_cell_leukemia	p.L35fs*51 (No)	GDSC	Tamoxifen	9.3479
SIDM00946	ALL\|T_cell_leukemia	p.L35fs*51 (No)	GDSC	Fulvestrant	4.7682
SIDM00946	ALL\|T_cell_leukemia	p.L35fs*51 (No)	GDSC	GDC0810	71.425
SIDM00716	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.I5V (No)	GDSC	Tamoxifen	50.2678
SIDM00716	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.I5V (No)	GDSC	Fulvestrant	54.59
SIDM00716	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.I5V (No)	GDSC	Tamoxifen	79.108
SIDM00716	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.I5V (No)	GDSC	Fulvestrant	12.204
SIDM00716	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.I5V (No)	GDSC	GDC0810	227.12
SIDM00195	UNCLASSIFIED\|ewings_sarcoma	p.R555H (No)	GDSC	Tamoxifen	50.844
SIDM00195	UNCLASSIFIED\|ewings_sarcoma	p.R555H (No)	GDSC	Fulvestrant	114.4903
SIDM00195	UNCLASSIFIED\|ewings_sarcoma	p.R555H (No)	GDSC	Tamoxifen	22.683
SIDM00195	UNCLASSIFIED\|ewings_sarcoma	p.R555H (No)	GDSC	Fulvestrant	9.4129
SIDM00195	UNCLASSIFIED\|ewings_sarcoma	p.R555H (No)	GDSC	GDC0810	139.2
SIDM01141	OV\|ovary	p.P134L (No)	GDSC	Tamoxifen	60.0587
SIDM01141	OV\|ovary	p.P134L (No)	GDSC	Fulvestrant	189.2998
SIDM01141	OV\|ovary	p.P134L (No)	GDSC	Tamoxifen	49.739
SIDM01141	OV\|ovary	p.P134L (No)	GDSC	Fulvestrant	24.351
SIDM01141	OV\|ovary	p.P134L (No)	GDSC	GDC0810	148.19
SIDM00596	UCEC\|endometrium	p.R24C (No)	GDSC	Tamoxifen	48.3496
SIDM00596	UCEC\|endometrium	p.R24C (No)	GDSC	Fulvestrant	31.5927
SIDM00596	UCEC\|endometrium	p.R24C (No)	GDSC	Tamoxifen	69.015
SIDM00596	UCEC\|endometrium	p.R24C (No)	GDSC	Fulvestrant	29.18
SIDM00596	UCEC\|endometrium	p.R24C (No)	GDSC	GDC0810	237.68
SIDM00685	GBM\|glioma	p.P134R (No)	GDSC	Tamoxifen	32.3924
SIDM00685	GBM\|glioma	p.P134R (No)	GDSC	Fulvestrant	31.6886
SIDM00685	GBM\|glioma	p.P134R (No)	GDSC	Tamoxifen	14.682
SIDM00685	GBM\|glioma	p.P134R (No)	GDSC	Fulvestrant	11.5
SIDM00685	GBM\|glioma	p.P134R (No)	GDSC	GDC0810	49.146
SIDM00660	COREAD\|large_intestine	p.R24C (No)	GDSC	Tamoxifen	48.4464
SIDM00660	COREAD\|large_intestine	p.R24C (No)	GDSC	Fulvestrant	61.4291
SIDM00660	COREAD\|large_intestine	p.R24C (No)	GDSC	Tamoxifen	15.571
SIDM00660	COREAD\|large_intestine	p.R24C (No)	GDSC	Fulvestrant	37.344
SIDM00660	COREAD\|large_intestine	p.R24C (No)	GDSC	GDC0810	194.77
SIDM00534	COREAD\|large_intestine	p.E247K (No)	GDSC	Tamoxifen	18.4067
SIDM00534	COREAD\|large_intestine	p.E247K (No)	GDSC	Fulvestrant	37.8342
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.A141V (No)	GDSC	Tamoxifen	173.8344
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.A141V (No)	GDSC	Fulvestrant	317.4289
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.A141V (No)	GDSC	Tamoxifen	335.27
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.A141V (No)	GDSC	Fulvestrant	104.02
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.A141V (No)	GDSC	GDC0810	137.65
SIDM00487	COREAD\|large_intestine	p.G160S (No)	GDSC	Tamoxifen	67.9388
SIDM00487	COREAD\|large_intestine	p.G160S (No)	GDSC	Fulvestrant	79.5323
SIDM00487	COREAD\|large_intestine	p.G160S (No)	GDSC	Tamoxifen	14.313
SIDM00487	COREAD\|large_intestine	p.G160S (No)	GDSC	Fulvestrant	7.5074
SIDM00487	COREAD\|large_intestine	p.G160S (No)	GDSC	GDC0810	30.258
SIDM00282	COREAD\|large_intestine	p.I326fs*7 (No)	GDSC	Tamoxifen	127.0465
SIDM00282	COREAD\|large_intestine	p.I326fs*7 (No)	GDSC	Fulvestrant	36.6785
SIDM00282	COREAD\|large_intestine	p.I326fs*7 (No)	GDSC	Tamoxifen	62.196
SIDM00282	COREAD\|large_intestine	p.I326fs*7 (No)	GDSC	Fulvestrant	26.337
SIDM00282	COREAD\|large_intestine	p.I326fs*7 (No)	GDSC	GDC0810	167.61
SIDM01156	SCLC\|lung_small_cell_carcinoma	p.S450fs*6 (No)	GDSC	Tamoxifen	75.5062
SIDM01156	SCLC\|lung_small_cell_carcinoma	p.S450fs*6 (No)	GDSC	Fulvestrant	62.8281
SIDM01156	SCLC\|lung_small_cell_carcinoma	p.S450fs*6 (No)	GDSC	Tamoxifen	436.48
SIDM01156	SCLC\|lung_small_cell_carcinoma	p.S450fs*6 (No)	GDSC	Fulvestrant	60.431
SIDM01156	SCLC\|lung_small_cell_carcinoma	p.S450fs*6 (No)	GDSC	GDC0810	192.31
SIDM01008	DLBC\|B_cell_lymphoma	p.I5V (No)	GDSC	Tamoxifen	53.5949
SIDM01008	DLBC\|B_cell_lymphoma	p.I5V (No)	GDSC	Fulvestrant	154.1204
SIDM01008	DLBC\|B_cell_lymphoma	p.I5V (No)	GDSC	Tamoxifen	16.49
SIDM01008	DLBC\|B_cell_lymphoma	p.I5V (No)	GDSC	Fulvestrant	10.305
SIDM01008	DLBC\|B_cell_lymphoma	p.I5V (No)	GDSC	GDC0810	121.77
SIDM00748	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G42C (No)	GDSC	Tamoxifen	42.0518
SIDM00748	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G42C (No)	GDSC	Fulvestrant	24.3929
SIDM00748	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G42C (No)	GDSC	Tamoxifen	16.855
SIDM00748	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G42C (No)	GDSC	Fulvestrant	8.0946
SIDM00748	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G42C (No)	GDSC	GDC0810	95.941
SIDM00545	SKCM\|melanoma	p.M1I (No)	GDSC	Tamoxifen	102.579
SIDM00545	SKCM\|melanoma	p.M1I (No)	GDSC	Fulvestrant	91.8259
SIDM00545	SKCM\|melanoma	p.M1I (No)	GDSC	Tamoxifen	92.608
SIDM00545	SKCM\|melanoma	p.M1I (No)	GDSC	Fulvestrant	38.589
SIDM00545	SKCM\|melanoma	p.M1I (No)	GDSC	GDC0810	169.08
SIDM00373	UCEC\|endometrium	p.A40T (No)	GDSC	Tamoxifen	21.3184
SIDM00373	UCEC\|endometrium	p.A40T (No)	GDSC	Fulvestrant	23.5158
SIDM00373	UCEC\|endometrium	p.A40T (No)	GDSC	Tamoxifen	39.305
SIDM00373	UCEC\|endometrium	p.A40T (No)	GDSC	Fulvestrant	10.857
SIDM00373	UCEC\|endometrium	p.A40T (No)	GDSC	GDC0810	43.052
SIDM01097	UNCLASSIFIED\|ewings_sarcoma	p.I298V (No)	GDSC	Tamoxifen	12.9315
SIDM01097	UNCLASSIFIED\|ewings_sarcoma	p.I298V (No)	GDSC	Fulvestrant	31.7891
SIDM01097	UNCLASSIFIED\|ewings_sarcoma	p.I298V (No)	GDSC	Tamoxifen	34.2
SIDM01097	UNCLASSIFIED\|ewings_sarcoma	p.I298V (No)	GDSC	Fulvestrant	5.5922
SIDM01097	UNCLASSIFIED\|ewings_sarcoma	p.I298V (No)	GDSC	GDC0810	80.524
SIDM00606	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.R241L (No)	GDSC	Tamoxifen	14.4943
SIDM00606	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.R241L (No)	GDSC	Fulvestrant	173.2908
SIDM00606	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.R241L (No)	GDSC	Tamoxifen	31.542
SIDM00606	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.R241L (No)	GDSC	Fulvestrant	21.563
SIDM00606	LUSC\|lung_NSCLC_squamous_cell_carcinoma	p.R241L (No)	GDSC	GDC0810	82.846
SIDM00537	COREAD\|large_intestine	p.T182A (No)	GDSC	Tamoxifen	44.9683
SIDM00537	COREAD\|large_intestine	p.T182A (No)	GDSC	Fulvestrant	36.4069
SIDM00537	COREAD\|large_intestine	p.T182A (No)	GDSC	Tamoxifen	46.38
SIDM00537	COREAD\|large_intestine	p.T182A (No)	GDSC	Fulvestrant	7.6339
SIDM00537	COREAD\|large_intestine	p.T182A (No)	GDSC	GDC0810	70.242
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.R164I (No)	GDSC	Tamoxifen	8.6635
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.R164I (No)	GDSC	Fulvestrant	6.2743
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.R164I (No)	GDSC	Tamoxifen	7.0798
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.R164I (No)	GDSC	Fulvestrant	3.0487
SIDM00277	UNCLASSIFIED\|haematopoietic_neoplasm_other	p.R164I (No)	GDSC	GDC0810	28.103
SIDM00944	COREAD\|large_intestine	p.H6Y (No)	GDSC	Tamoxifen	100.5486
SIDM00944	COREAD\|large_intestine	p.H6Y (No)	GDSC	Fulvestrant	70.475
SIDM00944	COREAD\|large_intestine	p.H6Y (No)	GDSC	Tamoxifen	88.751
SIDM00944	COREAD\|large_intestine	p.H6Y (No)	GDSC	Fulvestrant	129.42
SIDM00944	COREAD\|large_intestine	p.H6Y (No)	GDSC	GDC0810	424.19
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.R548C (No)	GDSC	Tamoxifen	16.6486
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.R548C (No)	GDSC	Fulvestrant	24.7868
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.R548C (No)	GDSC	Tamoxifen	15.631
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.R548C (No)	GDSC	Fulvestrant	3.7337
SIDM00447	UNCLASSIFIED\|B_cell_leukemia	p.R548C (No)	GDSC	GDC0810	62.453
SIDM00193	COREAD\|large_intestine	p.E61K (No)	GDSC	Tamoxifen	110.2345
SIDM00193	COREAD\|large_intestine	p.E61K (No)	GDSC	Fulvestrant	215.9863
SIDM00193	COREAD\|large_intestine	p.S341L (No)	GDSC	Tamoxifen	110.2345
SIDM00193	COREAD\|large_intestine	p.S341L (No)	GDSC	Fulvestrant	215.9863
SIDM00193	COREAD\|large_intestine	p.D480G (No)	GDSC	Tamoxifen	110.2345
SIDM00193	COREAD\|large_intestine	p.D480G (No)	GDSC	Fulvestrant	215.9863

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O00567	Nucleolar protein 56	DEG_SPOP_SBC_1	526:530	AGSTS	SPOP	0.9464	More...
O15027	Protein transport protein Sec16A	DEG_SPOP_SBC_1	959:963	AGSTS	SPOP	0.9989	More...
O76080	AN1-type zinc finger protein 5	DEG_SPOP_SBC_1	80:84	AGSTS	SPOP	0.9883	More...
P03372	Estrogen receptor	DEG_SPOP_SBC_1	571:575	AGSTS	SPOP	0.9845	More...
P15923	Transcription factor E2-alpha	DEG_SPOP_SBC_1	453:457	AGSTS	SPOP	0.9279	More...
Q13164	Mitogen-activated protein kinase 7	DEG_SPOP_SBC_1	621:625	AGSTS	SPOP	0.9979	More...
Q14186	Transcription factor Dp-1	DEG_SPOP_SBC_1	350:354	AGSTS	SPOP	0.9899	More...
Q70CQ4	Ubiquitin carboxyl-terminal hydrolase 31	DEG_SPOP_SBC_1	778:782	AGSTS	SPOP	0.7948	More...
Q96JN0	Ligand-dependent corepressor	DEG_SPOP_SBC_1	93:97	AGSTS	SPOP	0.9806	More...
Q99570	Phosphoinositide 3-kinase regulatory subunit 4	DEG_SPOP_SBC_1	1280:1284	AGSTS	SPOP	0.8593	More...
Q9BXF6	Rab11 family-interacting protein 5	DEG_SPOP_SBC_1	38:42	AGSTS	SPOP	0.7413	More...
Q9NQV8	PR domain zinc finger protein 8	DEG_SPOP_SBC_1	469:473	AGSTS	SPOP	0.9917	More...
Q9NW13	RNA-binding protein 28	DEG_SPOP_SBC_1	642:646	AGSTS	SPOP	0.9698	More...
Q9Y466	Nuclear receptor subfamily 2 group E member 1	DEG_SPOP_SBC_1	5:9	AGSTS	SPOP	0.7921	More...
Q9Y5Q3	Transcription factor MafB	DEG_SPOP_SBC_1	309:313	AGSTS	SPOP	0.9235	More...
Q86XD8	AN1-type zinc finger protein 4	DEG_SPOP_SBC_1	574:578	AGSTS	SPOP	0.9676	More...
Q8IYL3	UPF0688 protein C1orf174	DEG_SPOP_SBC_1	33:37	AGSTS	SPOP	0.9615	More...
Q86X59	Putative uncharacterized protein LINC02875	DEG_SPOP_SBC_1	166:170	AGSTS	SPOP	0.9773	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons

Degron: AGSTS

Degron related mutations and impact score

Drug responses associated with ESR1 mutations

All proteins holding degron of AGSTS