DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
CGC
Degron:
PETTT
Uniprot ID:
Q63HN1
Source protein:
Putative protein FAM205B
Source gene:
FAM205BP
Class:
DEG_SPOP_SBC_1
Location:
292:296
E3 ligase:
SPOP
DEGRON score:
0.5845
ASA_SCORE:
80.22
COIL:
0.8544
CONS_SCORE:
0
DSS_SCORE:
0.6038
HELIX:
0.0436
FCONS_SCORE:
0
RIG_SCORE:
0.65
Degron related mutations and impact score
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Drug responses associated with FAM205BP mutations
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All proteins holding degron of PETTT
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Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q9ULL0
Acrosomal protein KIAA1210
DEG_SPOP_SBC_1
602:606
PETTT
SPOP
0.8571
More...
Q08379
Golgin subfamily A member 2
DEG_SPOP_SBC_1
56:60
PETTT
SPOP
0.8756
More...
Q8N9W4
Golgin subfamily A member 6-like protein 2
DEG_SPOP_SBC_1
58:62
PETTT
SPOP
0.9524
More...
Q9NYA3
Golgin subfamily A member 6A
DEG_SPOP_SBC_1
55:59
PETTT
SPOP
0.6277
More...
A6NDN3
Golgin subfamily A member 6B
DEG_SPOP_SBC_1
55:59
PETTT
SPOP
0.9725
More...
P07498
Kappa-casein
DEG_SPOP_SBC_1
170:174
PETTT
SPOP
0.991
More...
Q8WXI7
Mucin-16
DEG_SPOP_SBC_1
11177:11181
PETTT
SPOP
0.6393
More...
Q8WXI7
Mucin-16
DEG_SPOP_SBC_1
11429:11433
PETTT
SPOP
0.8471
More...
Q02505
Mucin-3A
DEG_SPOP_SBC_1
984:988
PETTT
SPOP
0.91
More...
P57071
PR domain zinc finger protein 15
DEG_SPOP_SBC_1
1263:1267
PETTT
SPOP
0.74
More...
Q6ZU69
Protein FAM205A
DEG_SPOP_SBC_1
562:566
PETTT
SPOP
0.6816
More...
Q92954
Proteoglycan 4
DEG_SPOP_SBC_1
928:932
PETTT
SPOP
0.9958
More...
Q63HN1
Putative protein FAM205B
DEG_SPOP_SBC_1
292:296
PETTT
SPOP
0.5845
More...
Q9UHW9
Solute carrier family 12 member 6
DEG_SPOP_SBC_1
4:8
PETTT
SPOP
0.9865
More...
O94817
Ubiquitin-like protein ATG12
DEG_SPOP_SBC_1
27:31
PETTT
SPOP
0.8998
More...
P13611
Versican core protein
DEG_SPOP_SBC_1
1844:1848
PETTT
SPOP
0.7668
More...
Showing 1 to 16 of 16 entries
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