Found 463 literature records

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Entrez ID	Description
574453	miR-495 likely functions as a tumor suppressor in acute myeloid leukemia with MLL rearrangements.
388	"In cancer cells in vitro or in vivo, RhoB functions as a tumor suppressor that restricts EGF receptor (EGFR) cell surface occupancy as well as Akt signaling"
4311	hypoxia negatively regulates the tumor suppressor function of NEP in prostate cancer
3605	"CD4, IL-17and Foxp3 may be involved in the tumor suppression caused by host immune response, and are related with non-small cell lung cancer invasion and metastasis."
50943	"CD4, IL-17and Foxp3 may be involved in the tumor suppression caused by host immune response, and are related with non-small cell lung cancer invasion and metastasis."
920	"CD4, IL-17and Foxp3 may be involved in the tumor suppression caused by host immune response, and are related with non-small cell lung cancer invasion and metastasis."
79961	"Our data show that DENND2D might function as a tumor suppressor-like gene, preventing survival and expansion of cells with genetic damage through apoptosis mechanism. Absence of DENND2D might play a permissive role, as an early event, in tumorigenesis."
406962	our findings established a tumor-suppressive role for miR-186 in the progression of NSCLC.
407044	"miR-7-5p may represent a novel tumor suppressor miRNA in melanoma, acting at least in part via its inhibition of IRS-2 expression and oncogenic Akt signaling."
407045	"miR-7-5p may represent a novel tumor suppressor miRNA in melanoma, acting at least in part via its inhibition of IRS-2 expression and oncogenic Akt signaling."
407043	"miR-7-5p may represent a novel tumor suppressor miRNA in melanoma, acting at least in part via its inhibition of IRS-2 expression and oncogenic Akt signaling.[mirna-7-5p]"
406901	"p53-induced miR-107 suppresses brain tumor cell growth and down-regulates CDK6 and Notch-2 expression, supporting its tumor suppressor role and utility as a target for glioma therapy."
4221	The tumor suppressor protein menin inhibits NF-kappaB-mediated transactivation through recruitment of Sirt1 in hepatocellular carcinoma.
84816	RTN4IP1 has a tumor-suppressive function and may regulate thyroid cancer progression.
407024	miR-29b may function as a tumor suppressor by targeting ABL1 and BCR/ABL1.
494324	Tumor suppressor miR-375 regulates MYC expression via repression of CIP2A coding sequence through multiple miRNA-mRNA interactions.
285194	"The results suggest that loc285194 is a p53-regulated tumor suppressor, which acts in part through repression of miR-211."
100126343	study highlights the possible tumor suppressor role of miR-874 in NSCLC-initiating cells and suggests miR-874 as a potential target in the treatment of NSCLC.
2114	Our findings point to a tumor suppressor role for ETS2 in human NSCLC pathogenesis through inhibition of the MET proto-oncogene.
9093	Tid1 acts as a tumor suppressor by inhibiting EGFR signaling through interaction with EGFR/HSP70/HSP90 and enhancing EGFR ubiquitinylation and degradation.
100126333	MiR-708 may play an important role as a tumor suppressor in GBM.
3880	KRT19 is a potential tumor suppressor that negatively regulates Akt signaling through modulation of Egr1 nuclear localization.
407011	MicroRNA-23b functions as a tumor suppressor by regulating Zeb1 in bladder cancer.
11107	"Data provide the first causal link between Prdm5 loss and intestinal carcinogenesis, and uncover an extensive and novel PRDM5 target repertoire likely facilitating the tumor-suppressive functions of PRDM5."
574452	overexpressed in hepatocellular carcinoma and aids in transformation by regulating the G1/S cell cycle transition through targeting of the Mutated in Colorectal Cancer tumor suppressor
407001	MIR218 functions as a tumor suppressor by regulating SH3GL1 expression in medulloblastoma cancer cells.
43	Synaptic acetylcholinesterase may be a tumor suppressor and is modulated by miR-212 in non-small cell lung cancer.
619554	"miR-486 directly targets components of insulin growth factor (IGF) signaling including IGF1, IGF1 receptor, and phosphoinositide-3-kinase, regulatory subunit 1alpha (PIK3R1, or p85a) and functions as a potent tumor suppressor of lung cancer."
406986	MiR-203 may act as novel tumor suppressor in esophageal cancer through down-regulating the expression of Ran and miR-21.
406899	MIR-106a-5p functions as a tumor suppressor during the development of astrocytomas by targeting FASTK.
2070	Work shows a clear role for EYA4 as a putative tumor suppressor genes in non-small-cell lung cancer.
406937	"this study suggests that miR-145 modulates ovarian cancer growth and invasion by suppressing p70S6K1 and MUC1, functioning as a tumor suppressor."
100126306	miR-888 functions to promote prostate cancer progression and can suppress protein levels of the tumor suppressor genes RBL1 and SMAD4.
1528	Results define CYB5A as a novel prognostic factor for PDAC that exerts its tumor-suppressor function through autophagy induction and TRAF6 modulation.
6924	TCEB3C is a putative tumor suppressor gene of small intestinal neuroendocrine tumors
4149	Genetic and molecular findings provide powerful evidence that MAX is a tumor-suppressor gene involved in SCLC development.
407055	miR-99a functions as a tumor metastasis suppressor in Oral squamous cell carcinoma cells and mutually regulates IGF1R
406951	Validation of the important role of miR-16 as a tumor suppressor gene in glioma growth and invasiveness.
11074	TRIM31 might serve as a tumor suppressor in non-small cell lung cancer.
3579	Blockage of CXCR2 suppresses tumor growth of intrahepatic cholangiocellular carcinoma.
7182	TR4 nuclear receptor functions as a tumor suppressor for prostate tumorigenesis via modulation of DNA damage/repair system.
27129	Results imply that HSBP7 is likely to be a tumor suppressor gene regulated by p53 and its downregulation by hypermethylation may play a critical role in renal carcinogenesis.
6387	"These data demonstrate a functional tumor suppressive role for the normal expression of CXCL12 in pancreatic ducts, regulating both tumor growth andcellulardissemination to metastatic sites."
57107	PDSS2 has tumor-suppressing activity in human lung cancer cells by enhancing apoptosis and inhibiting tumorigenic capacity.
4082	Finding that MARCKS acts as a mediator of apoptosis in microsatellite stable colorectal cancer cells adds a novel tumor-suppressing function to the established roles of MARCKS in cell motility and proliferation.
406923	the tumor suppressor role of miR-133a in lung cancer
407012	"miR-24 functions as a novel tumor suppressor in gastric cancer, and the anti-oncogenic activity may involve its inhibition of the target gene REG4."
406985	These findings indicate that miR-200c exerts tumor-suppressive effects for NSCLC through the suppression of USP25 expression and suggests a new therapeutic application of miR-200c in the treatment of NSCLC.
152573	Shisa3 acts as a tumor suppressor by acceleration of beta-catenin degradation. Read More: http://www.atsjournals.org/doi/full/10.1164/rccm.201312-2256OC
55818	Results show that Jmjd1a was not essential for stem cell self-renewal but played a crucial role as a tumor suppressor.

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