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Dataset Description
  • Dataset Name: 17517326
  • Species: Rat
  • Method: Microarray
  • No. of Genes: 77
  • Tissue: Nucleus accumbens, amygdala, frontal cortex, caudate-putamen, and hippocampus
  • Phenotype: Alcohol-preferring, alcohol-nonpreferring
  • Publication: Kimpel et al. Alcohol. (2007) Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions. PubMed
  • Dataset Summary: The objective of this study was to determine if there are innate differences in gene expression in selected CNS regions between inbred alcohol-preferring (iP) and -non-preferring (iNP) rats. Gene expression was determined in the nucleus accumbens (ACB), amygdala (AMYG), frontal cortex (FC), caudate-putamen (CPU), and hippocampus (HIPP) of alcohol-naive adult male iP and iNP rats, using Affymetrix Rat Genome U34A microarrays (n = 6/strain). Using Linear Modeling for Microarray Analysis with a false discovery rate threshold of 0.1, there were 16 genes with differential expression in the ACB, 54 in the AMYG, 8 in the FC, 24 in the CPU, and 21 in the HIPP. All the fold change are iP vs. iNP fold change.

    Gene list of this dataset (77 genes)
    Page: 1 2 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    114017Gfm1G elongation factor, mitochondrial 12q31Gfm 
    362418Irak2interleukin-1 receptor-associated kinase 24q42Irak2 
    24534Ldhblactate dehydrogenase B4q44Ldhb 
    155918Lcp2lymphocyte cytosolic protein 210q12Lcp2 
    25211Lyzlysozyme7q22Lyz 
    83834Nrn1neuritin 1-Nrn1 
    266777Nptx1neuronal pentraxin 110q32.3Nptx1 
    114108Pdlim3PDZ and LIM domain 316q11Pdlim3 
    64198Pmpcbpeptidase (mitochondrial processing) beta4q11Pmpcb 
    81740Pcm1pericentriolar material 116q12.1Pcm1 
    24644Pgk1phosphoglycerate kinase 1Xq31Pgk1 
    29562Prps1phosphoribosyl pyrophosphate synthetase 1Xq35Prps1 
    297508Namptnicotinamide phosphoribosyltransferase6q16Pbef1 
    29672Psma5proteasome (prosome, macropain) subunit, alpha type 52q34Psma5 
    24750RT1-N3RT1 class Ib gene, H2-TL-like, grc region (N3)20p12RT1-N3 
    309622RT1-BbRT1 class II, locus Bb20p12RT1-Bb 
    81921Sh3gl3SH3-domain GRB2-like 31q31Sh3gl3 
    301255Spats1spermatogenesis associated, serine-rich 19q12Spats1 
    25541Scp2sterol carrier protein 25q35Scp2 
    25357Thrspthyroid hormone responsive protein1q32Thrsp 
    58835Phgdh3-phosphoglycerate dehydrogenase2q34Phgdh 
    300850Gsta4glutathione S-transferase, alpha 48q31Gsta4 
    83789Rps2ribosomal protein S210q12Rps2 
    497770Scn3asodium channel, voltage-gated, type III, alpha3q21Scn3a 
    114507Slc5a3solute carrier family 5 (inositol transporters), member 311q11Slc5a3 
    24387Gfapglial fibrillary acidic protein10q32.1Gfap 
    24644Pgk1phosphoglycerate kinase 1Xq31Pgk1 
    29672Psma5proteasome (prosome, macropain) subunit, alpha type 52q34Psma5 
    58835Phgdh3-phosphoglycerate dehydrogenase2q34Phgdh 
    316051Azi25-azacytidine induced gene 28q32Azi2 
    308923Ahi1Abelson helper integration site 11p12Ahi1 
    24223B2mbeta-2 microglobulin3q35B2m 
    25661Fn1fibronectin 19q33Fn1 
    300850Gsta4glutathione S-transferase, alpha 48q31Gsta4 
    59073Lxnlatexin2q31Lxn 
    64633Rab5aRAB5A, member RAS oncogene family9q11Rab5a 
    83789Rps2ribosomal protein S210q12Rps2 
    24737RT1-Aw2RT1 class Ib, locus Aw220p12RT1-Aw2 
    308993Sephs2selenophosphate synthetase 21q36Sephs2 
    361813Stk38serine/threonine kinase 3820p12Stk38 
    114507Slc5a3solute carrier family 5 (inositol transporters), member 311q11Slc5a3 
    25123Taglntransgelin8q24Tagln 
    498549Akap11A kinase (PRKA) anchor protein 1115q11Akap11 
    29139Dcndecorin7q13Dcn 
    58844Grb14growth factor receptor bound protein 143q21Grb14 
    116967Magt1magnesium transporter 1Xq31Iag2 
    24644Pgk1phosphoglycerate kinase 1Xq31Pgk1 
    24750RT1-N3RT1 class Ib gene, H2-TL-like, grc region (N3)20p12RT1-N3 
    65047Slit1slit homolog 1 (Drosophila)1q54Slit1 
    58835Phgdh3-phosphoglycerate dehydrogenase2q34Phgdh 
    Page: 1 2 list all