Group: CAMK
Parent of:
CAMKL, CAMK1, CAMK2, CAMK-Unique, CASK, RAD53, DAPK, DCAMKL, Trio, MAPKAPK, MLCK, PHK, PIM, PKD, PSK, STK33, SgK495, Trbl, TSSK,
Description:
Calcium/Calmodulin regulated kinases and structurally related kinase families
Kinase with mutated hotspots in Group:CAMK
| Uniprot ID |
Gene symbol |
Gatekeeper location |
G loop location |
A loop location |
αC-Helix location |
| Q8TDC3 | BRSK1 | 110 | 173...184, 186...195 | [N/A] | [N/A] |
| Q14012 | CAMK1 | [N/A] | [N/A] | [N/A] | 66...70 |
| Q8IU85 | CAMK1D | 98 | 164...186 | [N/A] | 66...75 |
| Q96NX5 | CAMK1G | 97 | 163...184 | [N/A] | 64...74 |
| Q9UQM7 | CAMK2A | [N/A] | [N/A] | [N/A] | 33...35 |
| Q13554 | CAMK2B | [N/A] | [N/A] | [N/A] | 52...67 |
| Q13557 | CAMK2D | [N/A] | [N/A] | [N/A] | 47...49 |
| Q16566 | CAMK4 | [N/A] | [N/A] | [N/A] | 91...95 |
| Q8NCB2 | CAMKV | 99 | 165...185 | [N/A] | [N/A] |
| O14757 | CHEK1 | [N/A] | 147...172 | 15...21 | 42...44 |
| O96017 | CHEK2 | 301 | 367...377, 381...389 | 226...232 | 253...256 |
| P53355 | DAPK1 | 93 | 160...182 | 19...25 | 58...70 |
| Q9UIK4 | DAPK2 | 103 | 170...192 | 29...35 | 68...80 |
| O43293 | DAPK3 | 93 | 160...182 | 19...25 | 49...51 |
| O15075 | DCLK1 | 465 | [N/A] | 396...402 | 436...440 |
| Q9C098 | DCLK3 | 431 | 498...518 | [N/A] | [N/A] |
| P57058 | HUNK | 140 | 203...218, 220...228 | [N/A] | [N/A] |
| P49137 | MAPKAPK2 | 138 | 206...228 | 71...78 | 99...111 |
| Q16644 | MAPKAPK3 | 118 | 186...195, 197...207 | 51...58 | 79...91 |
| Q8IW41 | MAPKAPK5 | 102 | 168...178, 180...188 | [N/A] | [N/A] |
| Q9P0L2 | MARK1 | 136 | 199...221 | 66...72 | 98...113 |
| Q7KZI7 | MARK2 | [N/A] | [N/A] | 58...68 | 91...106 |
| Q96L34 | MARK4 | [N/A] | [N/A] | 65...71 | 92...94 |
| Q14680 | MELK | 86 | 149...160, 162...173 | [N/A] | 44...47 |
| Q9BUB5 | MKNK1 | 124 | 231...261 | 55...61 | 87...101 |
| Q9HBH9 | MKNK2 | 159 | 225...255 | [N/A] | 123...135 |
| Q15746 | MYLK | 1538 | 1604...1626 | [N/A] | [N/A] |
| Q9H1R3 | MYLK2 | 359 | 425...447 | [N/A] | [N/A] |
| Q32MK0 | MYLK3 | 589 | 655...677 | [N/A] | [N/A] |
| Q86YV6 | MYLK4 | [N/A] | [N/A] | 109...122 | 142...155 |
| Q8IY84 | NIM1K | 168 | 213...235 | [N/A] | [N/A] |
| O60285 | NUAK1 | 132 | 195...217 | [N/A] | [N/A] |
| Q5VST9 | OBSCN | 7745 | 6606...6628, 7808...7832 | [N/A] | [N/A] |
| Q96RG2 | PASK | [N/A] | [N/A] | [N/A] | 1051...1056 |
| Q16816 | PHKG1 | 104 | 167...189 | [N/A] | [N/A] |
| P15735 | PHKG2 | 107 | 170...192 | [N/A] | 64...84 |
| P11309 | PIM1 | 211 | 276...297 | [N/A] | 162...164 |
| Q9P1W9 | PIM2 | 116 | 181...202 | 37...47 | 82...91 |
| Q13131 | PRKAA1 | 104 | 167...189 | 33...42 | 60...66 |
| P54646 | PRKAA2 | 93 | 156...178 | 22...28 | 49...54 |
| O94806 | PRKD3 | 652 | 719...741 | [N/A] | [N/A] |
| Q96QS6 | PSKH2 | 137 | [N/A] | [N/A] | [N/A] |
| P57059 | SIK1 | 103 | 166...188 | [N/A] | [N/A] |
| Q9H0K1 | SIK2 | 96 | 159...181 | [N/A] | [N/A] |
| Q15831 | STK11 | 129 | 193...218 | 55...64 | 82...87 |
| Q9UEE5 | STK17A | 138 | 206...228 | [N/A] | [N/A] |
| O94768 | STK17B | 110 | 178...200 | 40...47 | 74...86 |
| Q9BYT3 | STK33 | 192 | 264...278, 280...288 | [N/A] | [N/A] |
| Q8N2I9 | STK40 | 141 | 215...238 | [N/A] | 81...97 |
| Q96RU8 | TRIB1 | 152 | [N/A] | [N/A] | 124...130 |
| Q92519 | TRIB2 | 130 | [N/A] | [N/A] | [N/A] |
| Q96RU7 | TRIB3 | 129 | [N/A] | [N/A] | [N/A] |
| O75962 | TRIO | 2869 | 2935...2957 | [N/A] | [N/A] |
| Q9BXA7 | TSSK1B | 90 | 153...180 | [N/A] | [N/A] |
| Q96PF2 | TSSK2 | 90 | 153...180 | [N/A] | [N/A] |
| Q96PN8 | TSSK3 | 88 | 150...174 | [N/A] | [N/A] |
| Q6SA08 | TSSK4 | 102 | 165...176, 193...203 | [N/A] | [N/A] |
| Q9BXA6 | TSSK6 | 90 | 153...176 | [N/A] | [N/A] |
| Q8WZ42 | TTN | 32251 | 32317...32339 | 32184...32190 | 32214...32228 |