KinaseMD: Kinase mutations and drug responses
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BSML
CPH
CGC
Group:
Other
Parent of:
NAK
,
Aur
,
BUB
,
CAMKK
,
CDC7
,
IKK
,
CK2
,
Dusty
,
PEK
,
IRE
,
PKL
,
Haspin
,
MOS
,
NEK
,
NDK
,
NRBP
,
PAN3
,
TOPK
,
NKF4
,
NKF3
,
PEAK
,
VPS15
,
NKF2
,
SgK493
,
WEE
,
PLK
,
Other-Unique
,
Slob
,
NKF1
,
SCY1
,
ULK
,
SgK071
,
TBCK
,
NKF5
,
TLK
,
Bud32
,
TTK
,
KIS
,
WNK
,
Description:
The Other group contains several kinase families that do not fit within any of the other main kinase groups
Kinase with A-loop mutations in Group:Other
All kinase in Other
All substructure loci
Gatekeeper loci
G-loop loci
A-loop loci
αC-helix loci
Uniprot ID
Gene symbol
Gatekeeper location
G loop location
A loop location
αC-Helix location
Q9UQB9
AURKC
120
183...204
[N/A]
[N/A]
Q8N5S9
CAMKK1
230
292...315
[N/A]
[N/A]
Q96RR4
CAMKK2
267
329...352
170...177
198...204
O00311
CDC7
134
195...205, 366...378
[N/A]
98...110
P19784
CSNK2A2
114
175...185, 190...197
[N/A]
76...88
Q6XUX3
DSTYK
730
794...814
[N/A]
[N/A]
Q9BQI3
EIF2AK1
392
460...469, 484...495
[N/A]
[N/A]
P19525
EIF2AK2
366
431...440, 442...453
[N/A]
303...305
Q9P2K8
EIF2AK4
802
865...874, 881...889, 895...906
[N/A]
[N/A]
O75460
ERN1
642
710...725, 729...736
[N/A]
603...605
O14976
GAK
123
190...220, 222...225
[N/A]
76...92
P00540
MOS
139
218...233, 238...244
[N/A]
[N/A]
Q96PY6
NEK1
80
145...168
7...20
42...57
P51955
NEK2
86
158...170, 173...181
14...20
41...43
P51957
NEK4
83
148...171
[N/A]
[N/A]
Q9HC98
NEK6
122
189...212
[N/A]
[N/A]
Q8TDX7
NEK7
111
178...201
[N/A]
73...87
Q8TD19
NEK9
128
193...205, 207...216
[N/A]
[N/A]
Q96KB5
PBK
115
185...199, 200...211
[N/A]
34...37
Q8N165
PDIK1L
119
189...201, 209...223
[N/A]
[N/A]
Q99640
PKMYT1
187
250...272
117...124
148...164
P53350
PLK1
130
193...216
60...67
86...88
Q9NYY3
PLK2
159
222...245
89...96
115...118
Q9H4B4
PLK3
139
202...225
67...77
95...98
O00444
PLK4
89
153...176
18...24
45...50
O75716
STK16
98
165...191, 193...197
[N/A]
56...70
Q8TDR2
STK35
315
380...392, 406...420
[N/A]
[N/A]
Q9NRP7
STK36
80
142...165
[N/A]
[N/A]
Q9UHD2
TBK1
86
156...178
[N/A]
42...46
Q9UKI8
TLK1
538
606...635
[N/A]
[N/A]
P33981
TTK
602
663...688
[N/A]
557...559
Q8TAS1
UHMK1
111
176...196
[N/A]
[N/A]
Q8IYT8
ULK2
85
157...179
[N/A]
[N/A]
Q6PHR2
ULK3
91
156...166, 168...178
[N/A]
[N/A]
Q96C45
ULK4
75
138...152, 178...184
[N/A]
[N/A]
P30291
WEE1
376
462...481
306...313
338...352
P0C1S8
WEE2
289
379...398
[N/A]
[N/A]
Q9H4A3
WNK1
301
367...388
[N/A]
266...273
Q9BYP7
WNK3
227
293...314
[N/A]
[N/A]
Q96J92
WNK4
254
320...341
[N/A]
[N/A]