ERGR - Ethanol-Related Gene Resource

Dataset Description

Dataset Name: 15002731

Species: Mouse

No. of Genes: 55

Tissue: Whole brain

Phenotype: Acute ethanol response

Publication: Treadwell et al. Neurochem Res. (2004) Microarray analysis of mouse brain gene expression following acute ethanol treatment. PubMed

Dataset Summary: We have analyzed the expression of approximately 24,000 genes using oligonucleotide microarrays to examine the brain expression profiles in two strains of inbred mice, C57BL/6J and DBA/2J, following exposure to an acute dose of ethanol. Our screen identified 61 genes responding to the ethanol treatment beyond a 1.5-fold threshold, with 46 genes altered in both mouse strains and 15 altered in only one strain.

Gene list of this dataset (55 genes)

GeneID Symbol Name Genetic location Original ID1 Original ID2
AWI21294
12575 Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 17 A3.3|17 15.23 cM AW048937
27273 Pdk4 pyruvate dehydrogenase kinase, isoenzyme 4 6 A1|6 0.63 cM AJ001418
20393 Sgk1 serum/glucocorticoid regulated kinase 1 10 A3 AW046181
170755 Sgk3 serum/glucocorticoid regulated kinase 3 1 A2|1 7.5 cM AA982701
12609 Cebpd CCAAT/enhancer binding protein (C/EBP), delta 16 A2|16 9.0 cM X61800
97165 Hmgb2 high mobility group box 2 8 B2 X67668
16601 Klf9 Kruppel-like factor 9 19 C1 Y14296
66277 Klf15 Kruppel-like factor 15 6 D1 AI852911
18088 Nkx2-2 NK2 transcription factor related, locus 2 (Drosophila) 2 H|2 82.0 cM U31566
20674 Sox2 SRY-box containing gene 2 3 A2-B|3 15.0 cM X94127
21847 Klf10 Kruppel-like factor 10 15 B3.1 AF064088
102538 AI553024
74747 Ddit4 DNA-damage-inducible transcript 4 10 B3 AI849939
23882 Gadd45g growth arrest and DNA-damage-inducible 45 gamma 13 A5-B AF055638
17748 Mt1 metallothionein 1 8 C5|8 45.0 cM V00835
17750 Mt2 metallothionein 2 8 C5|8 45.0 cM K02236
60599 Trp53inp1 transformation related protein 53 inducible nuclear protein 1 4 A1-A2 AI835817
56338 Txnip thioredoxin interacting protein 3 47.1 cM AI839138
12228 Btg3 B-cell translocation gene 3 16 C3.1 D83745
13867 Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 10 D3|10 70.0 cM AI006228
17433 Mobp myelin-associated oligodendrocytic basic protein 9 F4|9 69.0 cM AI836582
140742 Sesn1 sestrin 1 10 B2|10 25.0 cM AI843106
54698 Crtam cytotoxic and regulatory T cell molecule 9 A5.1|9 20.5 cM AF001104
13024 Ctla2a cytotoxic T lymphocyte-associated protein 2 alpha 13 B2|13 36.0 cM X15591
14229 Fkbp5 FK506 binding protein 5 17 A3.3|17 13.0 cM U16959
18035 Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 12 C1-C3 U57524
18035 Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 12 C1-C3 AI642048
67996 Sfrs6 splicing factor, arginine/serine-rich 6 2 H2|2 79.8 cM AI846595
225027 Sfrs7 splicing factor, arginine/serine-rich 7 17 E3 AW120954
20525 Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 4 D2.1|4 52.0 cM M22998
28250 Slco1a4 solute carrier organic anion transporter family, member 1a4 6 G2 AI843160
AV376312
74646 Spsb1 splA/ryanodine receptor domain and SOCS box containing 1 4 E2 AI596360
74155 Errfi1 ERBB receptor feedback inhibitor 1 4 E1 AI853531
66282 1810029B16Rik RIKEN cDNA 1810029B16 gene 8 B3.3 AI020512
66949 Trim59 tripartite motif-containing 59 3 E2 AI851230
67664 Rnf125 ring finger protein 125 18 A2 AI158278
68310 Zmym1 zinc finger, MYM domain containing 1 4 D2.2 AW209050
226178 D19Wsu162e DNA segment, Chr 19, Wayne State University 162, expressed 19 C3|19 50.0 cM AW047083
101214 Tra2a transformer 2 alpha homolog (Drosophila) 6 B2.3 AI841448
17355 Aff1 AF4/FMR2 family, member 1 5 E|5 56.0 cM AI836732
C85523
233335 Dmn desmuslin 7 C AW050361
AII81215
105171 Arrdc3 arrestin domain containing 3 13 C3 AI847396
102538 AW046458
216505 Pik3ip1 phosphoinositide-3-kinase interacting protein 1 11 A1 AI846040
56349 Net1 neuroepithelial cell transforming gene 1 13 A1 AJ010045
104156 Etv5 ets variant gene 5 16 B1 AW214004
17133 Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) 15 E1|15 46.0 cM AA060508
20682 Sox9 SRY-box containing gene 9 11 E2|11 69.5 cM AI852411
16431 Itm2a integral membrane protein 2A X A2-A3 L38971
17433 Mobp myelin-associated oligodendrocytic basic protein 9 F4|9 69.0 cM AI849019
19043 Ppm1b protein phosphatase 1B, magnesium dependent, beta isoform 17 E4-E5|17 50.8 cM D45859
71514 Sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) 4 D2.2|4 57.6 cM AW060546
12741 Cldn5 claudin 5 16 A3|16 11.65 cM U82758
U04827
103573 Xpo1 exportin 1, CRM1 homolog (yeast) 11 A3.2 AW123788
111662 Iap11-1 intracisternal A particles, Il3 linked 11 29.0 cM X04120
217410 Trib2 tribbles homolog 2 (Drosophila) 12 A1.1 AI842510
106572 Rab31 RAB31, member RAS oncogene family 17 E1.1 AW049806
AW123143
AW048189

GeneID	Symbol	Name	Genetic location	Original ID1	Original ID2
				AWI21294
12575	Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	17 A3.3\|17 15.23 cM	AW048937
27273	Pdk4	pyruvate dehydrogenase kinase, isoenzyme 4	6 A1\|6 0.63 cM	AJ001418
20393	Sgk1	serum/glucocorticoid regulated kinase 1	10 A3	AW046181
170755	Sgk3	serum/glucocorticoid regulated kinase 3	1 A2\|1 7.5 cM	AA982701
12609	Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	16 A2\|16 9.0 cM	X61800
97165	Hmgb2	high mobility group box 2	8 B2	X67668
16601	Klf9	Kruppel-like factor 9	19 C1	Y14296
66277	Klf15	Kruppel-like factor 15	6 D1	AI852911
18088	Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	2 H\|2 82.0 cM	U31566
20674	Sox2	SRY-box containing gene 2	3 A2-B\|3 15.0 cM	X94127
21847	Klf10	Kruppel-like factor 10	15 B3.1	AF064088
102538				AI553024
74747	Ddit4	DNA-damage-inducible transcript 4	10 B3	AI849939
23882	Gadd45g	growth arrest and DNA-damage-inducible 45 gamma	13 A5-B	AF055638
17748	Mt1	metallothionein 1	8 C5\|8 45.0 cM	V00835
17750	Mt2	metallothionein 2	8 C5\|8 45.0 cM	K02236
60599	Trp53inp1	transformation related protein 53 inducible nuclear protein 1	4 A1-A2	AI835817
56338	Txnip	thioredoxin interacting protein	3 47.1 cM	AI839138
12228	Btg3	B-cell translocation gene 3	16 C3.1	D83745
13867	Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	10 D3\|10 70.0 cM	AI006228
17433	Mobp	myelin-associated oligodendrocytic basic protein	9 F4\|9 69.0 cM	AI836582
140742	Sesn1	sestrin 1	10 B2\|10 25.0 cM	AI843106
54698	Crtam	cytotoxic and regulatory T cell molecule	9 A5.1\|9 20.5 cM	AF001104
13024	Ctla2a	cytotoxic T lymphocyte-associated protein 2 alpha	13 B2\|13 36.0 cM	X15591
14229	Fkbp5	FK506 binding protein 5	17 A3.3\|17 13.0 cM	U16959
18035	Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	12 C1-C3	U57524
18035	Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	12 C1-C3	AI642048
67996	Sfrs6	splicing factor, arginine/serine-rich 6	2 H2\|2 79.8 cM	AI846595
225027	Sfrs7	splicing factor, arginine/serine-rich 7	17 E3	AW120954
20525	Slc2a1	solute carrier family 2 (facilitated glucose transporter), member 1	4 D2.1\|4 52.0 cM	M22998
28250	Slco1a4	solute carrier organic anion transporter family, member 1a4	6 G2	AI843160
				AV376312
74646	Spsb1	splA/ryanodine receptor domain and SOCS box containing 1	4 E2	AI596360
74155	Errfi1	ERBB receptor feedback inhibitor 1	4 E1	AI853531
66282	1810029B16Rik	RIKEN cDNA 1810029B16 gene	8 B3.3	AI020512
66949	Trim59	tripartite motif-containing 59	3 E2	AI851230
67664	Rnf125	ring finger protein 125	18 A2	AI158278
68310	Zmym1	zinc finger, MYM domain containing 1	4 D2.2	AW209050
226178	D19Wsu162e	DNA segment, Chr 19, Wayne State University 162, expressed	19 C3\|19 50.0 cM	AW047083
101214	Tra2a	transformer 2 alpha homolog (Drosophila)	6 B2.3	AI841448
17355	Aff1	AF4/FMR2 family, member 1	5 E\|5 56.0 cM	AI836732
				C85523
233335	Dmn	desmuslin	7 C	AW050361
				AII81215
105171	Arrdc3	arrestin domain containing 3	13 C3	AI847396
102538				AW046458
216505	Pik3ip1	phosphoinositide-3-kinase interacting protein 1	11 A1	AI846040
56349	Net1	neuroepithelial cell transforming gene 1	13 A1	AJ010045
104156	Etv5	ets variant gene 5	16 B1	AW214004
17133	Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	15 E1\|15 46.0 cM	AA060508
20682	Sox9	SRY-box containing gene 9	11 E2\|11 69.5 cM	AI852411
16431	Itm2a	integral membrane protein 2A	X A2-A3	L38971
17433	Mobp	myelin-associated oligodendrocytic basic protein	9 F4\|9 69.0 cM	AI849019
19043	Ppm1b	protein phosphatase 1B, magnesium dependent, beta isoform	17 E4-E5\|17 50.8 cM	D45859
71514	Sfpq	splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)	4 D2.2\|4 57.6 cM	AW060546
12741	Cldn5	claudin 5	16 A3\|16 11.65 cM	U82758
				U04827
103573	Xpo1	exportin 1, CRM1 homolog (yeast)	11 A3.2	AW123788
111662	Iap11-1	intracisternal A particles, Il3 linked	11 29.0 cM	X04120
217410	Trib2	tribbles homolog 2 (Drosophila)	12 A1.1	AI842510
106572	Rab31	RAB31, member RAS oncogene family	17 E1.1	AW049806
				AW123143
				AW048189