DegronMD

Uniprot ID: P05155

Source protein: Plasma protease C1 inhibitor

Source gene: SERPING1

Class: DEG_SPOP_SBC_1

Location: 26:30

E3 ligase: SPOP

DEGRON score: 0.9771

ASA_SCORE: 70.9

COIL: 0.9146

CONS_SCORE: 0.5705

DSS_SCORE: 0.7138

HELIX: 0.0598

FCONS_SCORE: 1.2776

RIG_SCORE: 0.5717

Degron related mutations and impact score

Show entries

Search:

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A26D	TCGA-19-5956	GBM	TCGA	ATSSS	DEG_SPOP_SBC_1	0.7793
p.A31D	DO13863	GBM	ICGC	ATSSS	DEG_SPOP_SBC_1	0.3056
p.G23D	DO232224	PBCA	ICGC	ATSSS	DEG_SPOP_SBC_1	0.25
p.E33K	DO37406	SKCM	ICGC	ATSSS	DEG_SPOP_SBC_1	0.25
p.Q37R	DO228733	LICA	ICGC	ATSSS	DEG_SPOP_SBC_1	0.1389
p.N17H	DO41572	UCEC	ICGC	ATSSS	DEG_SPOP_SBC_1	0.0833
p.R40I	TCGA-55-8510	LUAD	TCGA	ATSSS	DEG_SPOP_SBC_1	0.0556

Showing 1 to 7 of 7 entries

Previous1Next

Drug responses associated with SERPING1 mutations

Show entries

Search:

Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
No data available in table

Showing 0 to 0 of 0 entries

PreviousNext

All proteins holding degron of ATSSS

Show entries

Search:

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8IZF2	Adhesion G protein-coupled receptor F5	DEG_SPOP_SBC_1	1330:1334	ATSSS	SPOP	0.8435	More...
Q86XP3	ATP-dependent RNA helicase DDX42	DEG_SPOP_SBC_1	41:45	ATSSS	SPOP	0.9905	More...
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	DEG_SPOP_SBC_1	463:467	ATSSS	SPOP	0.9992	More...
Q9NPF0	CD320 antigen	DEG_SPOP_SBC_1	214:218	ATSSS	SPOP	0.9034	More...
P51788	Chloride channel protein 2	DEG_SPOP_SBC_1	861:865	ATSSS	SPOP	0.98	More...
Q14004	Cyclin-dependent kinase 13	DEG_SPOP_SBC_1	263:267	ATSSS	SPOP	0.9936	More...
Q8IV53	DENN domain-containing protein 1C	DEG_SPOP_SBC_1	631:635	ATSSS	SPOP	0.9832	More...
Q96T88	E3 ubiquitin-protein ligase UHRF1	DEG_SPOP_SBC_1	389:393	ATSSS	SPOP	0.5185	More...
Q99814	Endothelial PAS domain-containing protein 1	DEG_SPOP_SBC_1	472:476	ATSSS	SPOP	0.9851	More...
P42566	Epidermal growth factor receptor substrate 15	DEG_SPOP_SBC_1	742:746	ATSSS	SPOP	0.9945	More...
O15372	Eukaryotic translation initiation factor 3 subunit H	DEG_SPOP_SBC_1	12:16	ATSSS	SPOP	0.9947	More...
Q9BTV5	Fibronectin type III and SPRY domain-containing protein 1	DEG_SPOP_SBC_1	487:491	ATSSS	SPOP	0.9287	More...
Q9UHL9	General transcription factor II-I repeat domain-containing protein 1	DEG_SPOP_SBC_1	248:252	ATSSS	SPOP	0.8868	More...
P13807	Glycogen [starch] synthase, muscle	DEG_SPOP_SBC_1	714:718	ATSSS	SPOP	0.9984	More...
Q9UPS6	Histone-lysine N-methyltransferase SETD1B	DEG_SPOP_SBC_1	1152:1156	ATSSS	SPOP	0.9555	More...
Q03252	Lamin-B2	DEG_SPOP_SBC_1	417:421	ATSSS	SPOP	0.9957	More...
O15481	Melanoma-associated antigen B4	DEG_SPOP_SBC_1	337:341	ATSSS	SPOP	0.9724	More...
Q6ZN16	Mitogen-activated protein kinase kinase kinase 15	DEG_SPOP_SBC_1	942:946	ATSSS	SPOP	0.807	More...
Q8WXI7	Mucin-16	DEG_SPOP_SBC_1	11879:11883	ATSSS	SPOP	0.9996	More...
Q685J3	Mucin-17	DEG_SPOP_SBC_1	666:670	ATSSS	SPOP	0.9384	More...
Q9HC84	Mucin-5B	DEG_SPOP_SBC_1	3039:3043	ATSSS	SPOP	0.9921	More...
Q9HC84	Mucin-5B	DEG_SPOP_SBC_1	4296:4300	ATSSS	SPOP	0.9858	More...
Q9HC84	Mucin-5B	DEG_SPOP_SBC_1	4723:4727	ATSSS	SPOP	0.9213	More...
Q92859	Neogenin	DEG_SPOP_SBC_1	1330:1334	ATSSS	SPOP	0.9832	More...
Q92540	Nonsense-mediated mRNA decay factor SMG7	DEG_SPOP_SBC_1	1063:1067	ATSSS	SPOP	0.9984	More...

Showing 1 to 25 of 47 entries

Previous1 2Next

DegronMD: protein-targeted degradation, mutation and drug response to degrons

Degron: ATSSS

Degron related mutations and impact score

Drug responses associated with SERPING1 mutations

All proteins holding degron of ATSSS