DegronMD - Q685J3(MUC17)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T1696N	TCGA-05-4410	LUAD	TCGA	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.5944
p.T1696N	DO25426	LUAD	ICGC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.5944
p.T1935S	TCGA-05-4410	LUAD	TCGA	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation altering degron motif	0.6005
p.T1935S	DO25426	LUAD	ICGC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation altering degron motif	0.6005
p.P2840L	TCGA-05-4410	LUAD	TCGA	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation altering degron motif	0.7582
p.P2840L	DO25426	LUAD	ICGC	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation altering degron motif	0.7582
p.P1760Q	TCGA-05-5420	LUAD	TCGA	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation altering degron motif	0.7035
p.P1760Q	DO26005	LUAD	ICGC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation altering degron motif	0.7035
p.P3717S	TCGA-05-5420	LUAD	TCGA	VTSTPVTT	DEG_SCF_FBW7_1	3720:3727	Mutation rewiring degron network	0.25
p.P3717S	TCGA-05-5420	LUAD	TCGA	PVTTS	DEG_SPOP_SBC_1	3724:3728	Mutation rewiring degron network	0.1389
p.P3717S	DO26005	LUAD	ICGC	VTSTPVTT	DEG_SCF_FBW7_1	3720:3727	Mutation rewiring degron network	0.25
p.P3717S	DO26005	LUAD	ICGC	PVTTS	DEG_SPOP_SBC_1	3724:3728	Mutation rewiring degron network	0.1389
p.P1407L	TCGA-06-0650	GBM	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.7582
p.P1407L	TCGA-A5-A0G2	UCEC	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.7582
p.P1407L	DO12628	GBM	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.7582
p.P1407L	DO41235	UCEC	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.7582
p.S2791F	TCGA-06-1805	GBM	TCGA	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation rewiring degron network	0.1667
p.S2791F	DO11567	GBM	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation rewiring degron network	0.1667
p.P1397L	TCGA-06-2557	GBM	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.1667
p.P1397L	TCGA-06-2557	GBM	TCGA	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1944
p.P1397L	TCGA-44-7662	LUAD	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.1667
p.P1397L	TCGA-44-7662	LUAD	TCGA	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1944
p.P1397L	TCGA-BR-6852	STAD	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.1667
p.P1397L	TCGA-BR-6852	STAD	TCGA	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1944
p.P1397L	TCGA-DB-A64L	LGG	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.1667
p.P1397L	TCGA-DB-A64L	LGG	TCGA	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1944
p.P1397L	TCGA-EO-A22R	UCEC	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.1667
p.P1397L	TCGA-EO-A22R	UCEC	TCGA	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1944
p.P1397L	DO13318	GBM	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.1667
p.P1397L	DO13318	GBM	ICGC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1944
p.P1397L	DO44615	LGG	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.1667
p.P1397L	DO44615	LGG	ICGC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1944
p.P1397L	DO23597	LUAD	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.1667
p.P1397L	DO23597	LUAD	ICGC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1944
p.P1397L	DO38202	STAD	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.1667
p.P1397L	DO38202	STAD	ICGC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1944
p.P1397L	DO42713	UCEC	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.1667
p.P1397L	DO42713	UCEC	ICGC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1944
p.P1397L	SIDM01146	Gastric Carcinoma	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.1667
p.P1397L	SIDM01146	Gastric Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1944
p.P1397L	SIDM01554	Mesothelioma	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.1667
p.P1397L	SIDM01554	Mesothelioma	GDSC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1944
p.P1397L	NCI-SNU-1	stomach	COSMIC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.1667
p.P1397L	NCI-SNU-1	stomach	COSMIC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1944
p.S1122Y	TCGA-06-5416	GBM	TCGA	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.0833
p.S1122Y	TCGA-56-7822	LUSC	TCGA	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.0833
p.S1122Y	DO10880	GBM	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.0833
p.S1122Y	DO26638	LUSC	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.0833
p.R2042W	TCGA-06-5418	GBM	TCGA	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.1111
p.R2042W	DO12274	GBM	ICGC	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.1111
p.R2042W	SIDM00789	Colorectal Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.1111
p.R2042W	ACH-000997	Colon/Colorectal Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.1111
p.R2042W	ACH-001061	Colon/Colorectal Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.1111
p.R2042W	HCT-15	large intestine	COSMIC	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.1111
p.T3232M	TCGA-09-1664	OV	TCGA	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.1667
p.T3232M	DO28147	OV	ICGC	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.1667
p.A961V	TCGA-09-2051	OV	TCGA	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0556
p.A961V	TCGA-09-2051	OV	TCGA	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1111
p.A961V	TCGA-09-2051	OV	TCGA	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.25
p.A961V	DO31450	OV	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0556
p.A961V	DO31450	OV	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1111
p.A961V	DO31450	OV	ICGC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.25
p.T3560S	TCGA-14-1823	GBM	TCGA	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.1111
p.T3560S	DO12070	GBM	ICGC	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.1111
p.T318M	TCGA-16-0850	GBM	TCGA	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.1111
p.T318M	TCGA-V5-AASX	ESCA	TCGA	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.1111
p.T318M	TCGA-VQ-AA68	STAD	TCGA	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.1111
p.T318M	DO12160	GBM	ICGC	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.1111
p.T318M	DO51799	STAD	ICGC	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.1111
p.I1283M	TCGA-17-Z000	LUAD	TCGA	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.0556
p.I1283M	TCGA-17-Z000	LUAD	TCGA	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.3056
p.P2167A	TCGA-17-Z000	LUAD	TCGA	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation altering degron motif	0.6392
p.S3054G	TCGA-17-Z001	LUAD	TCGA	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation altering degron motif	0.6993
p.P3061L	TCGA-17-Z020	LUAD	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.1944
p.P3061L	TCGA-17-Z020	LUAD	TCGA	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.1944
p.T1261A	TCGA-17-Z045	LUAD	TCGA	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.25
p.T1261A	TCGA-17-Z045	LUAD	TCGA	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.1111
p.A3554P	TCGA-17-Z045	LUAD	TCGA	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.2778
p.T1759M	TCGA-17-Z055	LUAD	TCGA	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation altering degron motif	0.7423
p.T1759M	TCGA-17-Z055	LUAD	TCGA	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation altering degron motif	0.7423
p.T1759M	TCGA-HT-7687	LGG	TCGA	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation altering degron motif	0.7423
p.T1759M	TCGA-HT-7687	LGG	TCGA	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation altering degron motif	0.7423
p.T1759M	DO22151	LGG	ICGC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation altering degron motif	0.7423
p.T1759M	DO22151	LGG	ICGC	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation altering degron motif	0.7423
p.E468Q	TCGA-18-3406	LUSC	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation rewiring degron network	0.2778
p.E468Q	TCGA-18-3406	LUSC	TCGA	PVSTT	DEG_SPOP_SBC_1	458:462	Mutation rewiring degron network	0.1667
p.E468Q	DO26438	LUSC	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation rewiring degron network	0.2778
p.E468Q	DO26438	LUSC	ICGC	PVSTT	DEG_SPOP_SBC_1	458:462	Mutation rewiring degron network	0.1667
p.S1140L	TCGA-18-3409	LUSC	TCGA	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.1944
p.S1140L	TCGA-GN-A8LK	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.1944
p.S1140L	DO26444	LUSC	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.1944
p.S1140L	DO51259	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.1944
p.D931H	TCGA-18-3416	LUSC	TCGA	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation altering degron motif	0.6577
p.D931H	DO26423	LUSC	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation altering degron motif	0.6577
p.T3644A	TCGA-19-5954	GBM	TCGA	PVSTT	DEG_SPOP_SBC_1	3641:3645	Mutation altering degron motif	0.7139
p.T3644A	DO11459	GBM	ICGC	PVSTT	DEG_SPOP_SBC_1	3641:3645	Mutation altering degron motif	0.7139
p.S401N	TCGA-19-5956	GBM	TCGA	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation rewiring degron network	0.0833
p.S401N	DO13863	GBM	ICGC	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation rewiring degron network	0.0833
p.E2118G	TCGA-20-1686	OV	TCGA	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.2778
p.E2118G	TCGA-20-1686	OV	TCGA	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1667
p.E2118G	DO31380	OV	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.2778
p.E2118G	DO31380	OV	ICGC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1667
p.L826H	TCGA-21-1079	LUSC	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation altering degron motif	0.7313
p.L826H	DO26846	LUSC	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation altering degron motif	0.7313
p.G3653V	TCGA-22-4596	LUSC	TCGA	PVSTT	DEG_SPOP_SBC_1	3641:3645	Mutation rewiring degron network	0.1111
p.G3653V	DO27739	LUSC	ICGC	PVSTT	DEG_SPOP_SBC_1	3641:3645	Mutation rewiring degron network	0.1111
p.T853N	TCGA-22-4613	LUSC	TCGA	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.0556
p.T853N	DO26468	LUSC	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.0556
p.T3310S	TCGA-22-4613	LUSC	TCGA	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation altering degron motif	0.6005
p.T3310S	DO26468	LUSC	ICGC	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation altering degron motif	0.6005
p.E1500K	TCGA-22-5479	LUSC	TCGA	AVSSS	DEG_SPOP_SBC_1	1491:1495	Mutation rewiring degron network	0.1944
p.E1500K	DO27287	LUSC	ICGC	AVSSS	DEG_SPOP_SBC_1	1491:1495	Mutation rewiring degron network	0.1944
p.T1889A	TCGA-22-A5C4	LUSC	TCGA	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.25
p.T1889A	DO45446	LUSC	ICGC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.25
p.S3984Y	TCGA-23-1110	OV	TCGA	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation rewiring degron network	0.1389
p.S3984Y	TCGA-23-1110	OV	TCGA	PSTSS	DEG_SPOP_SBC_1	3974:3978	Mutation rewiring degron network	0.1667
p.S3984Y	DO29398	OV	ICGC	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation rewiring degron network	0.1389
p.S3984Y	DO29398	OV	ICGC	PSTSS	DEG_SPOP_SBC_1	3974:3978	Mutation rewiring degron network	0.1667
p.S1326G	TCGA-23-1114	OV	TCGA	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.0833
p.S1326G	DO32337	OV	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.0833
p.G3513V	TCGA-24-0970	OV	TCGA	PVSTT	DEG_SPOP_SBC_1	3523:3527	Mutation rewiring degron network	0.0556
p.G3513V	DO30440	OV	ICGC	PVSTT	DEG_SPOP_SBC_1	3523:3527	Mutation rewiring degron network	0.0556
p.P3061S	TCGA-24-1845	OV	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.1944
p.P3061S	TCGA-24-1845	OV	TCGA	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.1944
p.P3061S	DO29920	OV	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.1944
p.P3061S	DO29920	OV	ICGC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.1944
p.Q1078L	TCGA-24-1847	OV	TCGA	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.3056
p.Q1078L	DO31080	OV	ICGC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.3056
p.P1932L	TCGA-24-1927	OV	TCGA	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation altering degron motif	0.7582
p.P1932L	DO31604	OV	ICGC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation altering degron motif	0.7582
p.P1849A	TCGA-24-2035	OV	TCGA	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.3056
p.P1849A	DO29598	OV	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.3056
p.V3229A	TCGA-28-5204	GBM	TCGA	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.25
p.V3229A	DO11884	GBM	ICGC	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.25
p.T4490M	TCGA-28-5216	GBM	TCGA	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation altering degron motif	0.7423
p.T4490M	TCGA-AC-A62Y	BRCA	TCGA	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation altering degron motif	0.7423
p.T4490M	TCGA-CG-5719	STAD	TCGA	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation altering degron motif	0.7423
p.T4490M	DO49021	BRCA	ICGC	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation altering degron motif	0.7423
p.T4490M	DO11513	GBM	ICGC	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation altering degron motif	0.7423
p.T4490M	DO38827	STAD	ICGC	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation altering degron motif	0.7423
p.T1075I	TCGA-28-5218	GBM	TCGA	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.2222
p.T1075I	DO13492	GBM	ICGC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.2222
p.T2784N	TCGA-29-1763	OV	TCGA	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation altering degron motif	0.7055
p.T2784N	TCGA-BA-5556	HNSC	TCGA	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation altering degron motif	0.7055
p.T2784N	DO14232	HNSC	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation altering degron motif	0.7055
p.T2784N	DO28422	OV	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation altering degron motif	0.7055
p.P1760S	TCGA-2W-A8YY	CESC	TCGA	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation altering degron motif	0.6752
p.P1760S	DO223732	CESC	ICGC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation altering degron motif	0.6752
p.P1760S	SIDM01605	Non-Small Cell Lung Carcinoma	GDSC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation altering degron motif	0.6752
p.P1760S	ACH-000891	Lung Cancer	CCLE	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation altering degron motif	0.6752
p.A2174V	TCGA-2W-A8YY	CESC	TCGA	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.25
p.A2174V	DO223732	CESC	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.25
p.Q4487H	TCGA-2Y-A9H3	LIHC	TCGA	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation rewiring degron network	0.3056
p.Q4487H	DO219525	LIHC	ICGC	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation rewiring degron network	0.3056
p.D419G	TCGA-32-2491	GBM	TCGA	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation rewiring degron network	0.1944
p.D419G	DO13354	GBM	ICGC	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation rewiring degron network	0.1944
p.V654L	TCGA-33-4566	LUSC	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation altering degron motif	0.5654
p.V654L	DO26790	LUSC	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation altering degron motif	0.5654
p.P3464T	TCGA-33-AAS8	LUSC	TCGA	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation altering degron motif	0.7031
p.P3464T	DO219123	LUSC	ICGC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation altering degron motif	0.7031
p.T825N	TCGA-33-AASB	LUSC	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.3056
p.T825N	DO219125	LUSC	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.3056
p.T825N	SIDM00148	Breast Carcinoma	GDSC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.3056
p.T825N	ACH-000019	Breast Cancer	CCLE	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.3056
p.T825N	ACH-000028	Breast Cancer	CCLE	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.3056
p.T825N	MCF7	breast	COSMIC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.3056
p.L1632P	TCGA-34-2604	LUSC	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation rewiring degron network	0.1667
p.L1632P	DO26433	LUSC	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation rewiring degron network	0.1667
p.Q1603E	TCGA-34-5231	LUSC	TCGA	LSTTPIDS	DEG_SCF_FBW7_1	1593:1600	Mutation rewiring degron network	0.25
p.Q1603E	TCGA-34-5231	LUSC	TCGA	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.1389
p.Q1603E	DO26772	LUSC	ICGC	LSTTPIDS	DEG_SCF_FBW7_1	1593:1600	Mutation rewiring degron network	0.25
p.Q1603E	DO26772	LUSC	ICGC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.1389
p.S3690N	TCGA-36-2534	OV	TCGA	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.0556
p.S3690N	DO29046	OV	ICGC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.0556
p.P276R	TCGA-37-4141	LUSC	TCGA	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation rewiring degron network	0.2778
p.P276R	DO26862	LUSC	ICGC	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation rewiring degron network	0.2778
p.T956N	TCGA-39-5029	LUSC	TCGA	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation altering degron motif	0.7055
p.T956N	DO27540	LUSC	ICGC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation altering degron motif	0.7055
p.A3956E	TCGA-39-5030	LUSC	TCGA	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.1111
p.A3956E	TCGA-39-5030	LUSC	TCGA	VSTPVIT	DEG_SCF_FBW7_1	3961:3967	Mutation rewiring degron network	0.1944
p.A3956E	TCGA-39-5030	LUSC	TCGA	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation rewiring degron network	0.1389
p.A3956E	TCGA-39-5030	LUSC	TCGA	VITST	DEG_SPOP_SBC_1	3965:3969	Mutation rewiring degron network	0.0833
p.A3956E	DO7418	CLLE	ICGC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.1111
p.A3956E	DO7418	CLLE	ICGC	VSTPVIT	DEG_SCF_FBW7_1	3961:3967	Mutation rewiring degron network	0.1944
p.A3956E	DO7418	CLLE	ICGC	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation rewiring degron network	0.1389
p.A3956E	DO7418	CLLE	ICGC	VITST	DEG_SPOP_SBC_1	3965:3969	Mutation rewiring degron network	0.0833
p.A3956E	DO27176	LUSC	ICGC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.1111
p.A3956E	DO27176	LUSC	ICGC	VSTPVIT	DEG_SCF_FBW7_1	3961:3967	Mutation rewiring degron network	0.1944
p.A3956E	DO27176	LUSC	ICGC	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation rewiring degron network	0.1389
p.A3956E	DO27176	LUSC	ICGC	VITST	DEG_SPOP_SBC_1	3965:3969	Mutation rewiring degron network	0.0833
p.T1405S	TCGA-3C-AALI	BRCA	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.6005
p.T1405S	TCGA-3C-AALI	BRCA	TCGA	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation altering degron motif	0.6005
p.T1405S	DO219589	BRCA	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.6005
p.T1405S	DO219589	BRCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation altering degron motif	0.6005
p.P299S	TCGA-3N-A9WC	SKCM	TCGA	LSTTPAAT	DEG_SCF_FBW7_1	295:302	Mutation altering degron motif	0.6752
p.P299S	DO222494	MELA	ICGC	LSTTPAAT	DEG_SCF_FBW7_1	295:302	Mutation altering degron motif	0.6752
p.P299S	DO51234	SKCM	ICGC	LSTTPAAT	DEG_SCF_FBW7_1	295:302	Mutation altering degron motif	0.6752
p.L1762H	TCGA-3P-A9WA	OV	TCGA	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation altering degron motif	0.6202
p.L1762H	DO50655	OV	ICGC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation altering degron motif	0.6202
p.K1601Q	TCGA-43-5668	LUSC	TCGA	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation substituting flanking lysine	0.1944
p.K1601Q	DO26608	LUSC	ICGC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation substituting flanking lysine	0.1944
p.T2715A	TCGA-43-A56V	LUSC	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	2712:2719	Mutation altering degron motif	0.7139
p.T2715A	DO45535	LUSC	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2712:2719	Mutation altering degron motif	0.7139
p.T1900P	TCGA-44-2657	LUAD	TCGA	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.2222
p.T1900P	DO25020	LUAD	ICGC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.2222
p.P2880Q	TCGA-44-2657	LUAD	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.7035
p.P2880Q	DO25020	LUAD	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.7035
p.S3075C	TCGA-44-2657	LUAD	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.2778
p.S3075C	DO25020	LUAD	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.2778
p.A1079T	TCGA-44-4112	LUAD	TCGA	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation altering degron motif	0.7139
p.A1079T	DO26032	LUAD	ICGC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation altering degron motif	0.7139
p.A1079T	SIDM00669	Pancreatic Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation altering degron motif	0.7139
p.A1079T	HPAF-II	pancreas	COSMIC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation altering degron motif	0.7139
p.T3947N	TCGA-44-6147	LUAD	TCGA	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation altering degron motif	0.5944
p.T3947N	TCGA-44-6147	LUAD	TCGA	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation altering degron motif	0.7055
p.T3947N	DO24740	LUAD	ICGC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation altering degron motif	0.5944
p.T3947N	DO24740	LUAD	ICGC	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation altering degron motif	0.7055
p.R942T	TCGA-49-4494	LUAD	TCGA	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.2778
p.R942T	TCGA-49-4494	LUAD	TCGA	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1111
p.R942T	TCGA-49-4494	LUAD	TCGA	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1389
p.R942T	TCGA-NK-A7XE	LUSC	TCGA	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.2778
p.R942T	TCGA-NK-A7XE	LUSC	TCGA	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1111
p.R942T	TCGA-NK-A7XE	LUSC	TCGA	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1389
p.R942T	DO24245	LUAD	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.2778
p.R942T	DO24245	LUAD	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1111
p.R942T	DO24245	LUAD	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1389
p.R942T	DO219215	LUSC	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.2778
p.R942T	DO219215	LUSC	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1111
p.R942T	DO219215	LUSC	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1389
p.A174V	TCGA-49-4505	LUAD	TCGA	MSTPLTT	DEG_SCF_FBW7_1	184:190	Mutation rewiring degron network	0.0556
p.A174V	DO25498	LUAD	ICGC	MSTPLTT	DEG_SCF_FBW7_1	184:190	Mutation rewiring degron network	0.0556
p.R4053S	TCGA-49-AARE	LUAD	TCGA	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation rewiring degron network	0.25
p.R4053S	DO218922	LUAD	ICGC	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation rewiring degron network	0.25
p.T2112M	TCGA-4Z-AA7S	BLCA	TCGA	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.7423
p.T2112M	TCGA-4Z-AA7S	BLCA	TCGA	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation altering degron motif	0.7423
p.T2112M	TCGA-HT-A74H	LGG	TCGA	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.7423
p.T2112M	TCGA-HT-A74H	LGG	TCGA	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation altering degron motif	0.7423
p.T2112M	DO218982	BLCA	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.7423
p.T2112M	DO218982	BLCA	ICGC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation altering degron motif	0.7423
p.T2112M	DO219815	LGG	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.7423
p.T2112M	DO219815	LGG	ICGC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation altering degron motif	0.7423
p.T2112M	NCI-H1836	lung	COSMIC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.7423
p.T2112M	NCI-H1836	lung	COSMIC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation altering degron motif	0.7423
p.P1897L	TCGA-50-5066	LUAD	TCGA	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.3056
p.P1897L	DO25040	LUAD	ICGC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.3056
p.V346F	TCGA-50-5931	LUAD	TCGA	LTSTPAST	DEG_SCF_FBW7_1	336:343	Mutation rewiring degron network	0.25
p.V346F	TCGA-50-5931	LUAD	TCGA	PLTST	DEG_SPOP_SBC_1	335:339	Mutation rewiring degron network	0.1389
p.V346F	DO24980	LUAD	ICGC	LTSTPAST	DEG_SCF_FBW7_1	336:343	Mutation rewiring degron network	0.25
p.V346F	DO24980	LUAD	ICGC	PLTST	DEG_SPOP_SBC_1	335:339	Mutation rewiring degron network	0.1389
p.P463T	TCGA-50-5933	LUAD	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation altering degron motif	0.7031
p.P463T	DO24800	LUAD	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation altering degron motif	0.7031
p.T3291I	TCGA-50-5935	LUAD	TCGA	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation altering degron motif	0.7078
p.T3291I	DO23588	LUAD	ICGC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation altering degron motif	0.7078
p.S407C	TCGA-50-6594	LUAD	TCGA	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation rewiring degron network	0.25
p.S407C	DO24275	LUAD	ICGC	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation rewiring degron network	0.25
p.V1839L	TCGA-52-7811	LUSC	TCGA	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1944
p.V1839L	DO26569	LUSC	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1944
p.P935S	TCGA-55-8089	LUAD	TCGA	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0833
p.P935S	TCGA-55-8089	LUAD	TCGA	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.3056
p.P935S	TCGA-D9-A6EC	SKCM	TCGA	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0833
p.P935S	TCGA-D9-A6EC	SKCM	TCGA	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.3056
p.P935S	DO23690	LUAD	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0833
p.P935S	DO23690	LUAD	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.3056
p.P935S	DO50291	SKCM	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0833
p.P935S	DO50291	SKCM	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.3056
p.S824G	TCGA-55-8092	LUAD	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.2778
p.S824G	DO26220	LUAD	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.2778
p.V536F	TCGA-55-8614	LUAD	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation altering degron motif	0.5957
p.V536F	TCGA-55-8614	LUAD	TCGA	VDTST	DEG_SPOP_SBC_1	536:540	Mutation altering degron motif	0.7068
p.V536F	DO48885	LUAD	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation altering degron motif	0.5957
p.V536F	DO48885	LUAD	ICGC	VDTST	DEG_SPOP_SBC_1	536:540	Mutation altering degron motif	0.7068
p.V1421F	TCGA-55-8616	LUAD	TCGA	LSATPVDT	DEG_SCF_FBW7_1	1416:1423	Mutation altering degron motif	0.5957
p.V1421F	TCGA-55-8616	LUAD	TCGA	VDTST	DEG_SPOP_SBC_1	1421:1425	Mutation altering degron motif	0.7068
p.V1421F	DO23566	LUAD	ICGC	LSATPVDT	DEG_SCF_FBW7_1	1416:1423	Mutation altering degron motif	0.5957
p.V1421F	DO23566	LUAD	ICGC	VDTST	DEG_SPOP_SBC_1	1421:1425	Mutation altering degron motif	0.7068
p.T2842N	TCGA-55-A494	LUAD	TCGA	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation altering degron motif	0.7055
p.T2842N	DO23794	LUAD	ICGC	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation altering degron motif	0.7055
p.A1590T	TCGA-55-A4DG	LUAD	TCGA	LSTTPIDS	DEG_SCF_FBW7_1	1593:1600	Mutation rewiring degron network	0.25
p.A1590T	DO26337	LUAD	ICGC	LSTTPIDS	DEG_SCF_FBW7_1	1593:1600	Mutation rewiring degron network	0.25
p.E3931D	TCGA-55-A4DG	LUAD	TCGA	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0556
p.E3931D	DO26337	LUAD	ICGC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0556
p.A1616D	TCGA-56-7222	LUSC	TCGA	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.2778
p.A1616D	DO26842	LUSC	ICGC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.2778
p.T3225A	TCGA-56-7730	LUSC	TCGA	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation altering degron motif	0.6028
p.T3225A	DO26617	LUSC	ICGC	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation altering degron motif	0.6028
p.P2457L	TCGA-59-2349	OV	TCGA	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1944
p.P2457L	DO220889	MELA	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1944
p.P2457L	DO28621	OV	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1944
p.S1528T	TCGA-61-1738	OV	TCGA	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.1667
p.S1528T	DO30380	OV	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.1667
p.G1265V	TCGA-61-2102	OV	TCGA	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1389
p.G1265V	TCGA-61-2102	OV	TCGA	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.2222
p.G1265V	DO31939	OV	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1389
p.G1265V	DO31939	OV	ICGC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.2222
p.A1431D	TCGA-62-A46O	LUAD	TCGA	LSATPVDT	DEG_SCF_FBW7_1	1416:1423	Mutation rewiring degron network	0.1111
p.A1431D	TCGA-62-A46O	LUAD	TCGA	VDTST	DEG_SPOP_SBC_1	1421:1425	Mutation rewiring degron network	0.1667
p.A1431D	TCGA-62-A46O	LUAD	TCGA	PGTTS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.3056
p.A1431D	DO26240	LUAD	ICGC	LSATPVDT	DEG_SCF_FBW7_1	1416:1423	Mutation rewiring degron network	0.1111
p.A1431D	DO26240	LUAD	ICGC	VDTST	DEG_SPOP_SBC_1	1421:1425	Mutation rewiring degron network	0.1667
p.A1431D	DO26240	LUAD	ICGC	PGTTS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.3056
p.S1553L	TCGA-63-7022	LUSC	TCGA	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.S1553L	DO26470	LUSC	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.S1553L	SIDM00581	Glioblastoma	GDSC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.S1553L	ACH-000738	Brain Cancer	CCLE	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.S1553L	GB-1	central nervous system	COSMIC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.S3552I	TCGA-63-A5MV	LUSC	TCGA	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation altering degron motif	0.7341
p.S3552I	DO219167	LUSC	ICGC	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation altering degron motif	0.7341
p.S833Y	TCGA-63-A5MW	LUSC	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation altering degron motif	0.712
p.S833Y	DO219169	LUSC	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation altering degron motif	0.712
p.V284M	TCGA-64-1676	LUAD	TCGA	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation altering degron motif	0.6097
p.V284M	DO23629	LUAD	ICGC	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation altering degron motif	0.6097
p.V284M	DO52689	MALY	ICGC	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation altering degron motif	0.6097
p.T1945N	TCGA-64-5774	LUAD	TCGA	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation blocking phosphorylation signal	0.5278
p.T1945N	DO24770	LUAD	ICGC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation blocking phosphorylation signal	0.5278
p.P458T	TCGA-66-2757	LUSC	TCGA	PVSTT	DEG_SPOP_SBC_1	458:462	Mutation altering degron motif	0.7031
p.P458T	DO26506	LUSC	ICGC	PVSTT	DEG_SPOP_SBC_1	458:462	Mutation altering degron motif	0.7031
p.E3219K	TCGA-66-2785	LUSC	TCGA	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.2778
p.E3219K	TCGA-DK-A3X1	BLCA	TCGA	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.2778
p.E3219K	DO447	BLCA	ICGC	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.2778
p.E3219K	DO26520	LUSC	ICGC	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.2778
p.E3219K	SIDM00749	Non-Small Cell Lung Carcinoma	GDSC	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.2778
p.E3219K	ACH-000916	Lung Cancer	CCLE	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.2778
p.E3219K	NCI-H1573	lung	COSMIC	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.2778
p.P2457T	TCGA-67-3770	LUAD	TCGA	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1944
p.P2457T	DO23932	LUAD	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1944
p.L2458I	TCGA-67-6217	LUAD	TCGA	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.2222
p.L2458I	DO25877	LUAD	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.2222
p.S3277C	TCGA-69-8255	LUAD	TCGA	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.0556
p.S3277C	DO25360	LUAD	ICGC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.0556
p.T951N	TCGA-70-6722	LUSC	TCGA	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation altering degron motif	0.7055
p.T951N	TCGA-70-6722	LUSC	TCGA	VDTST	DEG_SPOP_SBC_1	949:953	Mutation altering degron motif	0.7055
p.T951N	DO27755	LUSC	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation altering degron motif	0.7055
p.T951N	DO27755	LUSC	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation altering degron motif	0.7055
p.T951N	SIDM00232	Kidney Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation altering degron motif	0.7055
p.T951N	SIDM00232	Kidney Carcinoma	GDSC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation altering degron motif	0.7055
p.T951N	ACH-002168	Kidney Cancer	CCLE	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation altering degron motif	0.7055
p.T951N	ACH-002168	Kidney Cancer	CCLE	VDTST	DEG_SPOP_SBC_1	949:953	Mutation altering degron motif	0.7055
p.T951N	NCC021	kidney	COSMIC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation altering degron motif	0.7055
p.T951N	NCC021	kidney	COSMIC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation altering degron motif	0.7055
p.A2115S	TCGA-75-6214	LUAD	TCGA	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.6477
p.A2115S	DO24830	LUAD	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.6477
p.T2702M	TCGA-76-6286	GBM	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	2712:2719	Mutation rewiring degron network	0.0556
p.T2702M	TCGA-B5-A11X	UCEC	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	2712:2719	Mutation rewiring degron network	0.0556
p.T2702M	DO13552	GBM	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2712:2719	Mutation rewiring degron network	0.0556
p.T2702M	DO43130	UCEC	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2712:2719	Mutation rewiring degron network	0.0556
p.T3206S	TCGA-76-6286	GBM	TCGA	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.1111
p.T3206S	TCGA-76-6286	GBM	TCGA	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.3056
p.T3206S	DO13552	GBM	ICGC	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.1111
p.T3206S	DO13552	GBM	ICGC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.3056
p.S2877G	TCGA-76-6660	GBM	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.5882
p.S2877G	DO222737	COCA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.5882
p.S2877G	DO223728	GBM	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.5882
p.S1600Y	TCGA-77-A5G8	LUSC	TCGA	LSTTPIDS	DEG_SCF_FBW7_1	1593:1600	Mutation altering degron motif	0.712
p.S1600Y	DO50099	LUSC	ICGC	LSTTPIDS	DEG_SCF_FBW7_1	1593:1600	Mutation altering degron motif	0.712
p.I3966M	TCGA-78-7147	LUAD	TCGA	VSTPVIT	DEG_SCF_FBW7_1	3961:3967	Mutation altering degron motif	0.6507
p.I3966M	TCGA-78-7147	LUAD	TCGA	VITST	DEG_SPOP_SBC_1	3965:3969	Mutation altering degron motif	0.6507
p.I3966M	DO24527	LUAD	ICGC	VSTPVIT	DEG_SCF_FBW7_1	3961:3967	Mutation altering degron motif	0.6507
p.I3966M	DO24527	LUAD	ICGC	VITST	DEG_SPOP_SBC_1	3965:3969	Mutation altering degron motif	0.6507
p.S1495F	TCGA-78-7149	LUAD	TCGA	AVSSS	DEG_SPOP_SBC_1	1491:1495	Mutation altering degron motif	0.7982
p.S1495F	DO23790	LUAD	ICGC	AVSSS	DEG_SPOP_SBC_1	1491:1495	Mutation altering degron motif	0.7982
p.P4086T	TCGA-78-7155	LUAD	TCGA	ASSTT	DEG_SPOP_SBC_1	4079:4083	Mutation rewiring degron network	0.25
p.P4086T	DO23590	LUAD	ICGC	ASSTT	DEG_SPOP_SBC_1	4079:4083	Mutation rewiring degron network	0.25
p.A1616T	TCGA-78-7159	LUAD	TCGA	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.2778
p.A1616T	TCGA-EI-6507	READ	TCGA	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.2778
p.A1616T	TCGA-VP-A87D	PRAD	TCGA	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.2778
p.A1616T	DO23568	LUAD	ICGC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.2778
p.A1616T	DO51385	PRAD	ICGC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.2778
p.A1616T	DO36675	READ	ICGC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.2778
p.I1774T	TCGA-78-7166	LUAD	TCGA	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation altering degron motif	0.5966
p.I1774T	DO25629	LUAD	ICGC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation altering degron motif	0.5966
p.T664N	TCGA-85-8288	LUSC	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.1111
p.T664N	TCGA-85-8288	LUSC	TCGA	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.2778
p.T664N	DO26963	LUSC	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.1111
p.T664N	DO26963	LUSC	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.2778
p.S1410C	TCGA-85-A511	LUSC	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.7541
p.S1410C	DO45509	LUSC	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.7541
p.V660L	TCGA-86-7713	LUAD	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.2222
p.V660L	TCGA-86-7713	LUAD	TCGA	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.1667
p.V660L	DO229052	LICA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.2222
p.V660L	DO229052	LICA	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.1667
p.V660L	DO24712	LUAD	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.2222
p.V660L	DO24712	LUAD	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.1667
p.G1688R	TCGA-86-7954	LUAD	TCGA	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.6457
p.G1688R	DO23660	LUAD	ICGC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.6457
p.P1426H	TCGA-86-8054	LUAD	TCGA	PGTTS	DEG_SPOP_SBC_1	1426:1430	Mutation altering degron motif	0.7694
p.P1426H	DO23923	LUAD	ICGC	PGTTS	DEG_SPOP_SBC_1	1426:1430	Mutation altering degron motif	0.7694
p.D655E	TCGA-90-7769	LUSC	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation altering degron motif	0.5647
p.D655E	DO26822	LUSC	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation altering degron motif	0.5647
p.A3443V	TCGA-91-6831	LUAD	TCGA	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.0833
p.A3443V	TCGA-91-6831	LUAD	TCGA	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.1667
p.A3443V	DO23753	LUAD	ICGC	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.0833
p.A3443V	DO23753	LUAD	ICGC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.1667
p.A1254S	TCGA-92-8063	LUSC	TCGA	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation altering degron motif	0.7588
p.A1254S	DO26941	LUSC	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation altering degron motif	0.7588
p.T1406M	TCGA-93-A4JN	LUAD	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.7423
p.T1406M	TCGA-93-A4JN	LUAD	TCGA	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation altering degron motif	0.7423
p.T1406M	DO218931	LUAD	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.7423
p.T1406M	DO218931	LUAD	ICGC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation altering degron motif	0.7423
p.T1406M	DO27833	MALY	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.7423
p.T1406M	DO27833	MALY	ICGC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation altering degron motif	0.7423
p.S1414T	TCGA-95-7043	LUAD	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.2222
p.S1414T	TCGA-95-7043	LUAD	TCGA	LSATPVDT	DEG_SCF_FBW7_1	1416:1423	Mutation rewiring degron network	0.2778
p.S1414T	TCGA-95-7043	LUAD	TCGA	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1111
p.S1414T	TCGA-95-7043	LUAD	TCGA	VDTST	DEG_SPOP_SBC_1	1421:1425	Mutation rewiring degron network	0.1389
p.S1414T	DO24739	LUAD	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.2222
p.S1414T	DO24739	LUAD	ICGC	LSATPVDT	DEG_SCF_FBW7_1	1416:1423	Mutation rewiring degron network	0.2778
p.S1414T	DO24739	LUAD	ICGC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1111
p.S1414T	DO24739	LUAD	ICGC	VDTST	DEG_SPOP_SBC_1	1421:1425	Mutation rewiring degron network	0.1389
p.C4135S	TCGA-95-7043	LUAD	TCGA	PRTTT	DEG_SPOP_SBC_1	4130:4134	Mutation rewiring degron network	0.3056
p.C4135S	DO24739	LUAD	ICGC	PRTTT	DEG_SPOP_SBC_1	4130:4134	Mutation rewiring degron network	0.3056
p.A1771S	TCGA-95-A4VN	LUAD	TCGA	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation altering degron motif	0.6477
p.A1771S	DO51199	LUAD	ICGC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation altering degron motif	0.6477
p.D1127N	TCGA-97-7547	LUAD	TCGA	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.2222
p.D1127N	TCGA-DA-A1IC	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.2222
p.D1127N	DO23594	LUAD	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.2222
p.D1127N	DO37430	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.2222
p.E4050G	TCGA-98-A538	LUSC	TCGA	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation altering degron motif	0.7199
p.E4050G	DO219177	LUSC	ICGC	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation altering degron motif	0.7199
p.V2881M	TCGA-A3-A8OW	KIRC	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.6097
p.V2881M	DO219233	KIRC	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.6097
p.E704G	TCGA-A4-A57E	KIRP	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	708:715	Mutation rewiring degron network	0.2222
p.E704G	TCGA-A4-A57E	KIRP	TCGA	VDTST	DEG_SPOP_SBC_1	713:717	Mutation rewiring degron network	0.0833
p.E704G	DO44517	KIRP	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	708:715	Mutation rewiring degron network	0.2222
p.E704G	DO44517	KIRP	ICGC	VDTST	DEG_SPOP_SBC_1	713:717	Mutation rewiring degron network	0.0833
p.A300V	TCGA-A5-A0G1	UCEC	TCGA	LSTTPAAT	DEG_SCF_FBW7_1	295:302	Mutation altering degron motif	0.5825
p.A300V	DO42472	UCEC	ICGC	LSTTPAAT	DEG_SCF_FBW7_1	295:302	Mutation altering degron motif	0.5825
p.P463S	TCGA-A5-A0G2	UCEC	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation altering degron motif	0.6752
p.P463S	DO41235	UCEC	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation altering degron motif	0.6752
p.A725V	TCGA-A5-A0G2	UCEC	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	708:715	Mutation rewiring degron network	0.0556
p.A725V	TCGA-A5-A0G2	UCEC	TCGA	VDTST	DEG_SPOP_SBC_1	713:717	Mutation rewiring degron network	0.1111
p.A725V	DO41235	UCEC	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	708:715	Mutation rewiring degron network	0.0556
p.A725V	DO41235	UCEC	ICGC	VDTST	DEG_SPOP_SBC_1	713:717	Mutation rewiring degron network	0.1111
p.A961T	TCGA-A5-A0G2	UCEC	TCGA	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0556
p.A961T	TCGA-A5-A0G2	UCEC	TCGA	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1111
p.A961T	TCGA-A5-A0G2	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.25
p.A961T	DO41235	UCEC	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0556
p.A961T	DO41235	UCEC	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1111
p.A961T	DO41235	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.25
p.P1166H	TCGA-A5-A0G2	UCEC	TCGA	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation altering degron motif	0.7694
p.P1166H	DO41235	UCEC	ICGC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation altering degron motif	0.7694
p.V2069A	TCGA-A5-A0G2	UCEC	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation altering degron motif	0.5825
p.V2069A	DO41235	UCEC	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation altering degron motif	0.5825
p.S3650A	TCGA-A5-A0G2	UCEC	TCGA	PVSTT	DEG_SPOP_SBC_1	3641:3645	Mutation rewiring degron network	0.1944
p.S3650A	DO41235	UCEC	ICGC	PVSTT	DEG_SPOP_SBC_1	3641:3645	Mutation rewiring degron network	0.1944
p.P316L	TCGA-A5-A0GB	UCEC	TCGA	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.1667
p.P316L	DO41434	UCEC	ICGC	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.1667
p.P3135S	TCGA-A5-A1OF	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation altering degron motif	0.6752
p.P3135S	DO11854	GBM	ICGC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation altering degron motif	0.6752
p.P3135S	DO42568	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation altering degron motif	0.6752
p.P1420H	TCGA-A5-A2K5	UCEC	TCGA	LSATPVDT	DEG_SCF_FBW7_1	1416:1423	Mutation altering degron motif	0.7694
p.P1420H	DO41379	UCEC	ICGC	LSATPVDT	DEG_SCF_FBW7_1	1416:1423	Mutation altering degron motif	0.7694
p.P1420H	SIDM00902	Non-Small Cell Lung Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	1416:1423	Mutation altering degron motif	0.7694
p.P1420H	ACH-002337	Lung Cancer	CCLE	LSATPVDT	DEG_SCF_FBW7_1	1416:1423	Mutation altering degron motif	0.7694
p.A2823V	TCGA-A5-A2K7	UCEC	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.1389
p.A2823V	DO41271	UCEC	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.1389
p.V1349A	TCGA-A6-5665	COAD	TCGA	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.1667
p.V1349A	DO9756	COAD	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.1667
p.T3363N	TCGA-A6-5665	COAD	TCGA	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation rewiring degron network	0.1389
p.T3363N	DO9756	COAD	ICGC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation rewiring degron network	0.1389
p.T3199S	TCGA-A6-6649	COAD	TCGA	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.3056
p.T3199S	TCGA-A6-6649	COAD	TCGA	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.2778
p.T3199S	DO9186	COAD	ICGC	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.3056
p.T3199S	DO9186	COAD	ICGC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.2778
p.T4082M	TCGA-A6-6649	COAD	TCGA	ASSTT	DEG_SPOP_SBC_1	4079:4083	Mutation altering degron motif	0.7423
p.T4082M	DO9186	COAD	ICGC	ASSTT	DEG_SPOP_SBC_1	4079:4083	Mutation altering degron motif	0.7423
p.L2535F	TCGA-A6-6781	COAD	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation rewiring degron network	0.1667
p.L2535F	TCGA-A6-6781	COAD	TCGA	PVSTT	DEG_SPOP_SBC_1	2521:2525	Mutation rewiring degron network	0.0556
p.L2535F	DO8447	COAD	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation rewiring degron network	0.1667
p.L2535F	DO8447	COAD	ICGC	PVSTT	DEG_SPOP_SBC_1	2521:2525	Mutation rewiring degron network	0.0556
p.S609L	TCGA-A8-A095	BRCA	TCGA	ASSSS	DEG_SPOP_SBC_1	607:611	Mutation altering degron motif	0.7667
p.S609L	DO3940	BRCA	ICGC	ASSSS	DEG_SPOP_SBC_1	607:611	Mutation altering degron motif	0.7667
p.A1086S	TCGA-AA-3696	COAD	TCGA	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.25
p.A1086S	DO10004	COAD	ICGC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.25
p.S1274T	TCGA-AA-3697	COAD	TCGA	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.3056
p.S1274T	TCGA-AA-3697	COAD	TCGA	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.0556
p.S1274T	DO8424	COAD	ICGC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.3056
p.S1274T	DO8424	COAD	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.0556
p.S1274T	SIDM00831	Head and Neck Carcinoma	GDSC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.3056
p.S1274T	SIDM00831	Head and Neck Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.0556
p.S1274T	ACH-000207	Head and Neck Cancer	CCLE	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.3056
p.S1274T	ACH-000207	Head and Neck Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.0556
p.S1274T	Detroit562	upper aerodigestive tract	COSMIC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.3056
p.S1274T	Detroit562	upper aerodigestive tract	COSMIC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.0556
p.P2467L	TCGA-AA-3715	COAD	TCGA	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.3056
p.P2467L	DO8018	COAD	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.3056
p.T2869A	TCGA-AA-3811	COAD	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.1389
p.T2869A	DO7962	COAD	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.1389
p.R2342C	TCGA-AA-3864	COAD	TCGA	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.2778
p.R2342C	TCGA-G4-6588	COAD	TCGA	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.2778
p.R2342C	DO10140	COAD	ICGC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.2778
p.R2342C	DO8490	COAD	ICGC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.2778
p.G922R	TCGA-AA-3980	COAD	TCGA	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1111
p.G922R	DO8455	COAD	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1111
p.P3233S	TCGA-AA-3984	COAD	TCGA	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.1389
p.P3233S	DO9002	COAD	ICGC	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.1389
p.L3815S	TCGA-AA-A00N	COAD	TCGA	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.1667
p.L3815S	DO9876	COAD	ICGC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.1667
p.R4482Q	TCGA-AA-A010	COAD	TCGA	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation rewiring degron network	0.1667
p.R4482Q	SIDM01126	Small Cell Lung Carcinoma	GDSC	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation rewiring degron network	0.1667
p.R4482Q	SIDM00846	Cervical Carcinoma	GDSC	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation rewiring degron network	0.1667
p.R4482Q	SIDM00633	Breast Carcinoma	GDSC	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation rewiring degron network	0.1667
p.R4482Q	SIDM01588	Endometrial Carcinoma	GDSC	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation rewiring degron network	0.1667
p.T3957I	TCGA-AA-A01I	COAD	TCGA	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.T3957I	TCGA-AA-A01I	COAD	TCGA	VSTPVIT	DEG_SCF_FBW7_1	3961:3967	Mutation rewiring degron network	0.2222
p.T3957I	TCGA-AA-A01I	COAD	TCGA	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation rewiring degron network	0.1111
p.T3957I	TCGA-AA-A01I	COAD	TCGA	VITST	DEG_SPOP_SBC_1	3965:3969	Mutation rewiring degron network	0.1111
p.T3957I	DO10510	COAD	ICGC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.T3957I	DO10510	COAD	ICGC	VSTPVIT	DEG_SCF_FBW7_1	3961:3967	Mutation rewiring degron network	0.2222
p.T3957I	DO10510	COAD	ICGC	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation rewiring degron network	0.1111
p.T3957I	DO10510	COAD	ICGC	VITST	DEG_SPOP_SBC_1	3965:3969	Mutation rewiring degron network	0.1111
p.T1781A	TCGA-AB-2808	LAML	TCGA	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.1944
p.T1781A	DO21487	LAML	ICGC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.1944
p.T1781I	TCGA-AB-2808	LAML	TCGA	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.1944
p.T1781I	DO21487	LAML	ICGC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.1944
p.A4030V	TCGA-AB-2826	LAML	TCGA	PHTST	DEG_SPOP_SBC_1	4034:4038	Mutation rewiring degron network	0.2222
p.A4030V	DO21833	LAML	ICGC	PHTST	DEG_SPOP_SBC_1	4034:4038	Mutation rewiring degron network	0.2222
p.S2558P	TCGA-AB-2828	LAML	TCGA	VVTST	DEG_SPOP_SBC_1	2546:2550	Mutation rewiring degron network	0.1111
p.S2558P	DO21571	LAML	ICGC	VVTST	DEG_SPOP_SBC_1	2546:2550	Mutation rewiring degron network	0.1111
p.I1695M	TCGA-AD-6889	COAD	TCGA	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.6507
p.I1695M	DO8463	COAD	ICGC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.6507
p.I1695M	DO222553	COCA	ICGC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.6507
p.P3233L	TCGA-AD-6895	COAD	TCGA	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.1389
p.P3233L	DO8938	COAD	ICGC	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.1389
p.S2536P	TCGA-AG-3902	READ	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation rewiring degron network	0.1389
p.S2536P	TCGA-AG-3902	READ	TCGA	VVTST	DEG_SPOP_SBC_1	2546:2550	Mutation rewiring degron network	0.0556
p.S2536P	DO36407	READ	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation rewiring degron network	0.1389
p.S2536P	DO36407	READ	ICGC	VVTST	DEG_SPOP_SBC_1	2546:2550	Mutation rewiring degron network	0.0556
p.S545Y	TCGA-AG-A002	READ	TCGA	PVTTS	DEG_SPOP_SBC_1	541:545	Mutation altering degron motif	0.712
p.S545Y	TCGA-BS-A0UV	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	541:545	Mutation altering degron motif	0.712
p.S545Y	DO42793	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	541:545	Mutation altering degron motif	0.712
p.S840Y	TCGA-AG-A002	READ	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.1389
p.S840Y	TCGA-BS-A0UV	UCEC	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.1389
p.S840Y	DO42793	UCEC	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.1389
p.L1279I	TCGA-AG-A002	READ	TCGA	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.1667
p.L1279I	TCGA-AG-A002	READ	TCGA	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.1944
p.P1092L	TCGA-AG-A00Y	READ	TCGA	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.0833
p.P1092L	DO36542	READ	ICGC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.0833
p.T534I	TCGA-AJ-A3EL	UCEC	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation altering degron motif	0.7078
p.T534I	DO41542	UCEC	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation altering degron motif	0.7078
p.S3715P	TCGA-AJ-A3EL	UCEC	TCGA	VTSTPVTT	DEG_SCF_FBW7_1	3720:3727	Mutation rewiring degron network	0.1944
p.S3715P	TCGA-AJ-A3EL	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	3724:3728	Mutation rewiring degron network	0.0833
p.S3715P	DO41542	UCEC	ICGC	VTSTPVTT	DEG_SCF_FBW7_1	3720:3727	Mutation rewiring degron network	0.1944
p.S3715P	DO41542	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	3724:3728	Mutation rewiring degron network	0.0833
p.S3080Y	TCGA-AJ-A5DW	UCEC	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.1389
p.S3080Y	DO50075	UCEC	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.1389
p.T2255I	TCGA-AN-A046	BRCA	TCGA	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255I	TCGA-AN-A046	BRCA	TCGA	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255I	DO1285	BRCA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255I	DO1285	BRCA	ICGC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.P718L	TCGA-AN-A0AM	BRCA	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	708:715	Mutation rewiring degron network	0.25
p.P718L	TCGA-AN-A0AM	BRCA	TCGA	VDTST	DEG_SPOP_SBC_1	713:717	Mutation rewiring degron network	0.3056
p.P718L	DO4191	BRCA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	708:715	Mutation rewiring degron network	0.25
p.P718L	DO4191	BRCA	ICGC	VDTST	DEG_SPOP_SBC_1	713:717	Mutation rewiring degron network	0.3056
p.V2173G	TCGA-AP-A051	UCEC	TCGA	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.2778
p.V2173G	DO42673	UCEC	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.2778
p.V2463F	TCGA-AP-A054	UCEC	TCGA	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation altering degron motif	0.5957
p.V2463F	DO42256	UCEC	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation altering degron motif	0.5957
p.P535T	TCGA-AP-A059	UCEC	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation altering degron motif	0.7031
p.P535T	DO41361	UCEC	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation altering degron motif	0.7031
p.A1433T	TCGA-AP-A059	UCEC	TCGA	LSATPVDT	DEG_SCF_FBW7_1	1416:1423	Mutation rewiring degron network	0.0556
p.A1433T	TCGA-AP-A059	UCEC	TCGA	VDTST	DEG_SPOP_SBC_1	1421:1425	Mutation rewiring degron network	0.1111
p.A1433T	TCGA-AP-A059	UCEC	TCGA	PGTTS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.25
p.A1433T	DO41361	UCEC	ICGC	LSATPVDT	DEG_SCF_FBW7_1	1416:1423	Mutation rewiring degron network	0.0556
p.A1433T	DO41361	UCEC	ICGC	VDTST	DEG_SPOP_SBC_1	1421:1425	Mutation rewiring degron network	0.1111
p.A1433T	DO41361	UCEC	ICGC	PGTTS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.25
p.A673V	TCGA-AP-A0LM	UCEC	TCGA	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.25
p.A673V	TCGA-DU-A5TW	LGG	TCGA	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.25
p.A673V	DO44572	LGG	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.25
p.A673V	DO43306	UCEC	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.25
p.A673V	SIDM00413	B-Cell Non-Hodgkin's Lymphoma	GDSC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.25
p.A673V	WSU-DLCL2	haematopoietic and lymphoid tissue	COSMIC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.25
p.V936I	TCGA-AP-A0LM	UCEC	TCGA	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.1111
p.V936I	TCGA-AP-A0LM	UCEC	TCGA	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.2778
p.V936I	DO43306	UCEC	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.1111
p.V936I	DO43306	UCEC	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.2778
p.D1775G	TCGA-AP-A0LM	UCEC	TCGA	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation altering degron motif	0.6087
p.D1775G	DO43306	UCEC	ICGC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation altering degron motif	0.6087
p.V2232I	TCGA-AP-A1DK	UCEC	TCGA	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.V2232I	DO42033	UCEC	ICGC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.P2339S	TCGA-AP-A1DV	UCEC	TCGA	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1944
p.P2339S	DO43186	UCEC	ICGC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1944
p.P2834H	TCGA-AP-A1DV	UCEC	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation altering degron motif	0.7694
p.P2834H	DO43186	UCEC	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation altering degron motif	0.7694
p.T3138N	TCGA-AP-A1E0	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation altering degron motif	0.7055
p.T3138N	TCGA-CZ-5988	KIRC	TCGA	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation altering degron motif	0.7055
p.T3138N	DO17462	KIRC	ICGC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation altering degron motif	0.7055
p.T3138N	DO43154	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation altering degron motif	0.7055
p.V3293L	TCGA-AR-A1AO	BRCA	TCGA	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.1111
p.V3293L	TCGA-AR-A1AO	BRCA	TCGA	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.2778
p.V3293L	DO4443	BRCA	ICGC	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.1111
p.V3293L	DO4443	BRCA	ICGC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.2778
p.R279T	TCGA-AR-A251	BRCA	TCGA	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation altering degron motif	0.7876
p.R279T	DO5724	BRCA	ICGC	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation altering degron motif	0.7876
p.A319D	TCGA-AX-A06F	UCEC	TCGA	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.0833
p.A319D	DO41752	UCEC	ICGC	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.0833
p.K421T	TCGA-AX-A0J0	UCEC	TCGA	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation substituting flanking lysine	0.25
p.K421T	DO41133	UCEC	ICGC	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation substituting flanking lysine	0.25
p.G675C	TCGA-AX-A0J1	UCEC	TCGA	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.1944
p.G675C	DO41199	UCEC	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.1944
p.S3403N	TCGA-AX-A0J1	UCEC	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.25
p.S3403N	DO41199	UCEC	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.25
p.T1546I	TCGA-AX-A1CE	UCEC	TCGA	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.1944
p.T1546I	TCGA-AX-A1CE	UCEC	TCGA	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.25
p.T1546I	DO42280	UCEC	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.1944
p.T1546I	DO42280	UCEC	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.25
p.S4059F	TCGA-AX-A1CE	UCEC	TCGA	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation rewiring degron network	0.0833
p.S4059F	DO42280	UCEC	ICGC	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation rewiring degron network	0.0833
p.P653H	TCGA-AX-A2HC	UCEC	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation altering degron motif	0.7694
p.P653H	TCGA-DU-6392	LGG	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation altering degron motif	0.7694
p.P653H	DO22237	LGG	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation altering degron motif	0.7694
p.P653H	DO41572	UCEC	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation altering degron motif	0.7694
p.P935T	TCGA-AX-A2HC	UCEC	TCGA	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0833
p.P935T	TCGA-AX-A2HC	UCEC	TCGA	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.3056
p.P935T	TCGA-CV-7245	HNSC	TCGA	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0833
p.P935T	TCGA-CV-7245	HNSC	TCGA	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.3056
p.P935T	DO14322	HNSC	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0833
p.P935T	DO14322	HNSC	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.3056
p.P935T	DO41572	UCEC	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0833
p.P935T	DO41572	UCEC	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.3056
p.P3464H	TCGA-AX-A2HC	UCEC	TCGA	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation altering degron motif	0.7694
p.P3464H	DO41572	UCEC	ICGC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation altering degron motif	0.7694
p.M280T	TCGA-AX-A2HD	UCEC	TCGA	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation altering degron motif	0.6312
p.M280T	DO42608	UCEC	ICGC	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation altering degron motif	0.6312
p.T1536A	TCGA-AY-4070	COAD	TCGA	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.6028
p.T1536A	DO10518	COAD	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.6028
p.S3735Y	TCGA-AZ-4315	COAD	TCGA	AISSS	DEG_SPOP_SBC_1	3731:3735	Mutation altering degron motif	0.712
p.S3735Y	DO8842	COAD	ICGC	AISSS	DEG_SPOP_SBC_1	3731:3735	Mutation altering degron motif	0.712
p.S2165C	TCGA-AZ-4681	COAD	TCGA	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.2778
p.S2165C	DO9306	COAD	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.2778
p.T1684A	TCGA-B0-5098	KIRC	TCGA	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation rewiring degron network	0.2222
p.T1684A	DO18938	KIRC	ICGC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation rewiring degron network	0.2222
p.A3201S	TCGA-B5-A0JY	UCEC	TCGA	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation altering degron motif	0.7588
p.A3201S	DO43041	UCEC	ICGC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation altering degron motif	0.7588
p.S3532P	TCGA-B5-A0JY	UCEC	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation rewiring degron network	0.3056
p.S3532P	TCGA-B5-A0JY	UCEC	TCGA	PVSTT	DEG_SPOP_SBC_1	3523:3527	Mutation rewiring degron network	0.1944
p.S3532P	DO43041	UCEC	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation rewiring degron network	0.3056
p.S3532P	DO43041	UCEC	ICGC	PVSTT	DEG_SPOP_SBC_1	3523:3527	Mutation rewiring degron network	0.1944
p.I4483M	TCGA-B5-A0JY	UCEC	TCGA	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation rewiring degron network	0.1944
p.I4483M	DO43041	UCEC	ICGC	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation rewiring degron network	0.1944
p.P4054L	TCGA-B5-A0JZ	UCEC	TCGA	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation rewiring degron network	0.2222
p.P4054L	DO42761	UCEC	ICGC	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation rewiring degron network	0.2222
p.P4054L	SIDM00429	B-Lymphoblastic Leukemia	GDSC	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation rewiring degron network	0.2222
p.P4054L	ACH-000938	Leukemia	CCLE	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation rewiring degron network	0.2222
p.P4054L	NALM-6	haematopoietic and lymphoid tissue	COSMIC	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation rewiring degron network	0.2222
p.T1634I	TCGA-B5-A0K4	UCEC	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation rewiring degron network	0.2222
p.T1634I	DO42360	UCEC	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation rewiring degron network	0.2222
p.A878T	TCGA-B5-A0K6	UCEC	TCGA	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.1389
p.A878T	DO40808	UCEC	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.1389
p.T874I	TCGA-B5-A11E	UCEC	TCGA	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.25
p.T874I	DO41644	UCEC	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.25
p.P3935L	TCGA-B5-A11E	UCEC	TCGA	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.1667
p.P3935L	TCGA-B5-A11E	UCEC	TCGA	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation rewiring degron network	0.0556
p.P3935L	DO23250	LINC	ICGC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.1667
p.P3935L	DO23250	LINC	ICGC	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation rewiring degron network	0.0556
p.P3935L	DO41644	UCEC	ICGC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.1667
p.P3935L	DO41644	UCEC	ICGC	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation rewiring degron network	0.0556
p.G3653D	TCGA-B5-A11J	UCEC	TCGA	PVSTT	DEG_SPOP_SBC_1	3641:3645	Mutation rewiring degron network	0.1111
p.G3653D	DO43698	UCEC	ICGC	PVSTT	DEG_SPOP_SBC_1	3641:3645	Mutation rewiring degron network	0.1111
p.D2718E	TCGA-B5-A11O	UCEC	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	2712:2719	Mutation altering degron motif	0.5647
p.D2718E	TCGA-B5-A11O	UCEC	TCGA	VDTST	DEG_SPOP_SBC_1	2717:2721	Mutation altering degron motif	0.5647
p.D2718E	DO41650	UCEC	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2712:2719	Mutation altering degron motif	0.5647
p.D2718E	DO41650	UCEC	ICGC	VDTST	DEG_SPOP_SBC_1	2717:2721	Mutation altering degron motif	0.5647
p.S2831L	TCGA-B5-A11R	UCEC	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation altering degron motif	0.6556
p.S2831L	DO43787	UCEC	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation altering degron motif	0.6556
p.T658A	TCGA-B5-A3FA	UCEC	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.2778
p.T658A	TCGA-B5-A3FA	UCEC	TCGA	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.1111
p.T658A	DO52402	UCEC	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.2778
p.T658A	DO52402	UCEC	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.1111
p.P1161L	TCGA-B5-A3FA	UCEC	TCGA	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1944
p.P1161L	TCGA-EO-A22T	UCEC	TCGA	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1944
p.P1161L	TCGA-W3-AA1R	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1944
p.P1161L	DO51275	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1944
p.P1161L	DO42320	UCEC	ICGC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1944
p.P1161L	DO52402	UCEC	ICGC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1944
p.P522L	TCGA-B5-A3FC	UCEC	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation rewiring degron network	0.0833
p.P522L	DO229058	LICA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation rewiring degron network	0.0833
p.P522L	DO41871	UCEC	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation rewiring degron network	0.0833
p.S1081P	TCGA-B5-A3FC	UCEC	TCGA	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation altering degron motif	0.6752
p.S1081P	DO41871	UCEC	ICGC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation altering degron motif	0.6752
p.T2161I	TCGA-B5-A3FC	UCEC	TCGA	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.1667
p.T2161I	DO41871	UCEC	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.1667
p.S1645N	TCGA-B6-A1KN	BRCA	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation altering degron motif	0.7069
p.S1645N	DO3656	BRCA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation altering degron motif	0.7069
p.S854N	TCGA-B6-A40C	BRCA	TCGA	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.0833
p.S854N	DO50045	BRCA	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.0833
p.T1325A	TCGA-B7-5816	STAD	TCGA	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.0556
p.T1325A	DO38599	STAD	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.0556
p.S4012N	TCGA-B7-A5TI	STAD	TCGA	PSTPRTT	DEG_SCF_FBW7_1	4011:4017	Mutation altering degron motif	0.5958
p.S4012N	DO222328	STAD	ICGC	PSTPRTT	DEG_SCF_FBW7_1	4011:4017	Mutation altering degron motif	0.5958
p.T1429S	TCGA-BA-A6DE	HNSC	TCGA	PGTTS	DEG_SPOP_SBC_1	1426:1430	Mutation altering degron motif	0.6005
p.T1429S	DO44438	HNSC	ICGC	PGTTS	DEG_SPOP_SBC_1	1426:1430	Mutation altering degron motif	0.6005
p.E202K	TCGA-BA-A6DJ	HNSC	TCGA	PESTT	DEG_SPOP_SBC_1	201:205	Mutation altering degron motif	0.591
p.E202K	DO52034	HNSC	ICGC	PESTT	DEG_SPOP_SBC_1	201:205	Mutation altering degron motif	0.591
p.M457I	TCGA-BB-8596	HNSC	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation rewiring degron network	0.2778
p.M457I	TCGA-BB-8596	HNSC	TCGA	PVSTT	DEG_SPOP_SBC_1	458:462	Mutation rewiring degron network	0.3056
p.M457I	DO15599	HNSC	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation rewiring degron network	0.2778
p.M457I	DO15599	HNSC	ICGC	PVSTT	DEG_SPOP_SBC_1	458:462	Mutation rewiring degron network	0.3056
p.M457I	DO229036	LICA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation rewiring degron network	0.2778
p.M457I	DO229036	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	458:462	Mutation rewiring degron network	0.3056
p.G3279R	TCGA-BF-A1PV	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.1111
p.G3279R	DO47309	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.1111
p.P152L	TCGA-BF-A3DM	SKCM	TCGA	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation altering degron motif	0.7582
p.P152L	DO48667	SKCM	ICGC	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation altering degron motif	0.7582
p.S3744F	TCGA-BF-AAP0	SKCM	TCGA	AISSS	DEG_SPOP_SBC_1	3731:3735	Mutation rewiring degron network	0.0833
p.S3744F	DO219462	SKCM	ICGC	AISSS	DEG_SPOP_SBC_1	3731:3735	Mutation rewiring degron network	0.0833
p.P830S	TCGA-BF-AAP2	SKCM	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation altering degron motif	0.6752
p.P830S	DO225391	BRCA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation altering degron motif	0.6752
p.P830S	DO219466	SKCM	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation altering degron motif	0.6752
p.A1138T	TCGA-BF-AAP7	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.25
p.A1138T	DO219472	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.25
p.S3045C	TCGA-BH-A0E0	BRCA	TCGA	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.1389
p.S3045C	DO1384	BRCA	ICGC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.1389
p.S3080C	TCGA-BH-A0HK	BRCA	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.1389
p.S3080C	DO5717	BRCA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.1389
p.S1090R	TCGA-BH-A0W5	BRCA	TCGA	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.1389
p.S1090R	DO5528	BRCA	ICGC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.1389
p.S408C	TCGA-BH-A0W7	BRCA	TCGA	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation rewiring degron network	0.2778
p.S408C	DO1272	BRCA	ICGC	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation rewiring degron network	0.2778
p.T3981A	TCGA-BH-A1FC	BRCA	TCGA	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation rewiring degron network	0.2222
p.T3981A	TCGA-BH-A1FC	BRCA	TCGA	PSTSS	DEG_SPOP_SBC_1	3974:3978	Mutation rewiring degron network	0.25
p.T3981A	DO5661	BRCA	ICGC	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation rewiring degron network	0.2222
p.T3981A	DO5661	BRCA	ICGC	PSTSS	DEG_SPOP_SBC_1	3974:3978	Mutation rewiring degron network	0.25
p.S2844C	TCGA-BH-A2L8	BRCA	TCGA	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation altering degron motif	0.7541
p.S2844C	DO44242	BRCA	ICGC	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation altering degron motif	0.7541
p.A1590D	TCGA-BJ-A2P4	THCA	TCGA	LSTTPIDS	DEG_SCF_FBW7_1	1593:1600	Mutation rewiring degron network	0.25
p.A1590D	DO49750	THCA	ICGC	LSTTPIDS	DEG_SCF_FBW7_1	1593:1600	Mutation rewiring degron network	0.25
p.A347V	TCGA-BK-A6W3	UCEC	TCGA	LTSTPAST	DEG_SCF_FBW7_1	336:343	Mutation rewiring degron network	0.2222
p.A347V	TCGA-BK-A6W3	UCEC	TCGA	PLTST	DEG_SPOP_SBC_1	335:339	Mutation rewiring degron network	0.1111
p.A347V	DO50076	UCEC	ICGC	LTSTPAST	DEG_SCF_FBW7_1	336:343	Mutation rewiring degron network	0.2222
p.A347V	DO50076	UCEC	ICGC	PLTST	DEG_SPOP_SBC_1	335:339	Mutation rewiring degron network	0.1111
p.T934M	TCGA-BK-A6W3	UCEC	TCGA	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation altering degron motif	0.7423
p.T934M	TCGA-EO-A3AZ	UCEC	TCGA	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation altering degron motif	0.7423
p.T934M	TCGA-NH-A5IV	COAD	TCGA	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation altering degron motif	0.7423
p.T934M	DO49095	COAD	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation altering degron motif	0.7423
p.T934M	DO50076	UCEC	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation altering degron motif	0.7423
p.T934M	DO50078	UCEC	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation altering degron motif	0.7423
p.T2360K	TCGA-BP-4983	KIRC	TCGA	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation altering degron motif	0.6195
p.T2360K	DO16705	KIRC	ICGC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation altering degron motif	0.6195
p.E2041K	TCGA-BP-5173	KIRC	TCGA	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.0833
p.E2041K	TCGA-FW-A3R5	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.0833
p.E2041K	DO20289	KIRC	ICGC	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.0833
p.E2041K	DO37406	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.0833
p.T715I	TCGA-BR-4184	STAD	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	708:715	Mutation altering degron motif	0.7078
p.T715I	TCGA-BR-4184	STAD	TCGA	VDTST	DEG_SPOP_SBC_1	713:717	Mutation altering degron motif	0.7078
p.T715I	DO38328	STAD	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	708:715	Mutation altering degron motif	0.7078
p.T715I	DO38328	STAD	ICGC	VDTST	DEG_SPOP_SBC_1	713:717	Mutation altering degron motif	0.7078
p.P1538L	TCGA-BR-4253	STAD	TCGA	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.7582
p.P1538L	DO38455	STAD	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.7582
p.S952G	TCGA-BR-4370	STAD	TCGA	VDTST	DEG_SPOP_SBC_1	949:953	Mutation altering degron motif	0.6993
p.S952G	DO38499	STAD	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation altering degron motif	0.6993
p.T1640A	TCGA-BR-6452	STAD	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation altering degron motif	0.6028
p.T1640A	DO38404	STAD	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation altering degron motif	0.6028
p.T3196N	TCGA-BR-6455	STAD	TCGA	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation altering degron motif	0.7055
p.T3196N	DO38703	STAD	ICGC	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation altering degron motif	0.7055
p.S3555N	TCGA-BR-7704	STAD	TCGA	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.25
p.S3555N	DO38360	STAD	ICGC	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.25
p.P1328S	TCGA-BR-7707	STAD	TCGA	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.1389
p.P1328S	DO38487	STAD	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.1389
p.R2042Q	TCGA-BR-7707	STAD	TCGA	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.1111
p.R2042Q	DO38487	STAD	ICGC	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.1111
p.R2042Q	SIDM01665	Colorectal Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.1111
p.R2042Q	ACH-000089	Colon/Colorectal Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.1111
p.A524T	TCGA-BR-7851	STAD	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation rewiring degron network	0.1389
p.A524T	DO38711	STAD	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation rewiring degron network	0.1389
p.P2545L	TCGA-BR-8060	STAD	TCGA	VVTST	DEG_SPOP_SBC_1	2546:2550	Mutation rewiring degron network	0.3056
p.P2545L	DO38205	STAD	ICGC	VVTST	DEG_SPOP_SBC_1	2546:2550	Mutation rewiring degron network	0.3056
p.T2054M	TCGA-BR-8078	STAD	TCGA	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation altering degron motif	0.7423
p.T2054M	DO38288	STAD	ICGC	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation altering degron motif	0.7423
p.A465T	TCGA-BR-8081	STAD	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation altering degron motif	0.6028
p.A465T	DO38795	STAD	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation altering degron motif	0.6028
p.N2062T	TCGA-BR-8589	STAD	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation rewiring degron network	0.2778
p.N2062T	TCGA-BR-8589	STAD	TCGA	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.1111
p.N2062T	DO47813	STAD	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation rewiring degron network	0.2778
p.N2062T	DO47813	STAD	ICGC	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.1111
p.T3292M	TCGA-BR-8591	STAD	TCGA	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.0833
p.T3292M	TCGA-BR-8591	STAD	TCGA	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.3056
p.T3292M	DO47973	STAD	ICGC	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.0833
p.T3292M	DO47973	STAD	ICGC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.3056
p.T3292M	SIDM00449	B-Lymphoblastic Leukemia	GDSC	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.0833
p.T3292M	SIDM00449	B-Lymphoblastic Leukemia	GDSC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.3056
p.T3292M	ACH-000922	Leukemia	CCLE	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.0833
p.T3292M	ACH-000922	Leukemia	CCLE	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.3056
p.T3292M	RCH-ACV	haematopoietic and lymphoid tissue	COSMIC	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.0833
p.T3292M	RCH-ACV	haematopoietic and lymphoid tissue	COSMIC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.3056
p.T3973A	TCGA-BR-8680	STAD	TCGA	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation altering degron motif	0.7139
p.T3973A	DO47769	STAD	ICGC	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation altering degron motif	0.7139
p.D931N	TCGA-BR-A4QI	STAD	TCGA	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation altering degron motif	0.5821
p.D931N	DO38523	STAD	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation altering degron motif	0.5821
p.P1849S	TCGA-BS-A0TJ	UCEC	TCGA	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.3056
p.P1849S	DO42953	UCEC	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.3056
p.S3192N	TCGA-BS-A0UA	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.2778
p.S3192N	TCGA-BS-A0UA	UCEC	TCGA	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.0833
p.S3192N	DO42552	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.2778
p.S3192N	DO42552	UCEC	ICGC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.0833
p.A2886D	TCGA-BS-A0UF	UCEC	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.25
p.A2886D	DO41488	UCEC	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.25
p.S451R	TCGA-BS-A0UV	UCEC	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation rewiring degron network	0.1111
p.S451R	TCGA-BS-A0UV	UCEC	TCGA	PVSTT	DEG_SPOP_SBC_1	458:462	Mutation rewiring degron network	0.1389
p.S451R	DO42793	UCEC	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation rewiring degron network	0.1111
p.S451R	DO42793	UCEC	ICGC	PVSTT	DEG_SPOP_SBC_1	458:462	Mutation rewiring degron network	0.1389
p.S1549Y	TCGA-BS-A0UV	UCEC	TCGA	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.1111
p.S1549Y	TCGA-BS-A0UV	UCEC	TCGA	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.1667
p.S1549Y	DO42793	UCEC	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.1111
p.S1549Y	DO42793	UCEC	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.1667
p.S2235Y	TCGA-BS-A0UV	UCEC	TCGA	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1944
p.S2235Y	DO42793	UCEC	ICGC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1944
p.S3139Y	TCGA-BS-A0UV	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation altering degron motif	0.712
p.S3139Y	DO42793	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation altering degron motif	0.712
p.T3814N	TCGA-BS-A0UV	UCEC	TCGA	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.1944
p.T3814N	DO42793	UCEC	ICGC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.1944
p.F4493L	TCGA-BS-A0UV	UCEC	TCGA	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation rewiring degron network	0.3056
p.F4493L	DO42793	UCEC	ICGC	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation rewiring degron network	0.3056
p.S3149F	TCGA-BT-A2LB	BLCA	TCGA	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.0556
p.S3149F	DO44098	BLCA	ICGC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.0556
p.E1589D	TCGA-BT-A2LD	BLCA	TCGA	LSTTPIDS	DEG_SCF_FBW7_1	1593:1600	Mutation rewiring degron network	0.2222
p.E1589D	DO578	BLCA	ICGC	LSTTPIDS	DEG_SCF_FBW7_1	1593:1600	Mutation rewiring degron network	0.2222
p.E1176K	TCGA-BT-A42F	BLCA	TCGA	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1667
p.E1176K	DO49726	BLCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1667
p.S158L	TCGA-C5-A1BK	CESC	TCGA	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation rewiring degron network	0.25
p.S158L	DO6266	CESC	ICGC	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation rewiring degron network	0.25
p.S1777N	TCGA-C5-A7X5	CESC	TCGA	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.3056
p.S1777N	DO49894	CESC	ICGC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.3056
p.S1734C	TCGA-C5-A901	CESC	TCGA	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.0556
p.S1734C	DO49914	CESC	ICGC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.0556
p.G273V	TCGA-C8-A12K	BRCA	TCGA	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation rewiring degron network	0.1944
p.G273V	DO1258	BRCA	ICGC	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation rewiring degron network	0.1944
p.E940Q	TCGA-C8-A12T	BRCA	TCGA	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.2222
p.E940Q	TCGA-C8-A12T	BRCA	TCGA	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1667
p.E940Q	TCGA-C8-A12T	BRCA	TCGA	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.0833
p.E940Q	DO5507	BRCA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.2222
p.E940Q	DO5507	BRCA	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1667
p.E940Q	DO5507	BRCA	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.0833
p.S2176C	TCGA-C8-A12T	BRCA	TCGA	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.1944
p.S2176C	DO5507	BRCA	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.1944
p.S3555R	TCGA-CA-6717	COAD	TCGA	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.25
p.S3555R	DO8264	COAD	ICGC	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.25
p.G214V	TCGA-CD-8535	STAD	TCGA	PESTT	DEG_SPOP_SBC_1	201:205	Mutation rewiring degron network	0.0833
p.G214V	DO47741	STAD	ICGC	PESTT	DEG_SPOP_SBC_1	201:205	Mutation rewiring degron network	0.0833
p.A4088T	TCGA-CD-A4MG	STAD	TCGA	ASSTT	DEG_SPOP_SBC_1	4079:4083	Mutation rewiring degron network	0.1944
p.A4088T	DO48009	STAD	ICGC	ASSTT	DEG_SPOP_SBC_1	4079:4083	Mutation rewiring degron network	0.1944
p.V1898L	TCGA-CF-A47T	BLCA	TCGA	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.2778
p.V1898L	DO44057	BLCA	ICGC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.2778
p.P417H	TCGA-CK-5916	COAD	TCGA	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation rewiring degron network	0.25
p.P417H	DO8786	COAD	ICGC	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation rewiring degron network	0.25
p.M1091I	TCGA-CK-6746	COAD	TCGA	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.1111
p.M1091I	DO7938	COAD	ICGC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.1111
p.S1895G	TCGA-CM-4743	COAD	TCGA	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation altering degron motif	0.6993
p.S1895G	DO8103	COAD	ICGC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation altering degron motif	0.6993
p.E2885K	TCGA-CN-4723	HNSC	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.2778
p.E2885K	DO14830	HNSC	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.2778
p.E2885K	SIDM01322	Oral Cavity Carcinoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.2778
p.E2885K	ACH-000735	Head and Neck Cancer	CCLE	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.2778
p.S549N	TCGA-CN-A63V	HNSC	TCGA	ASSSS	DEG_SPOP_SBC_1	548:552	Mutation altering degron motif	0.5958
p.S549N	DO44417	HNSC	ICGC	ASSSS	DEG_SPOP_SBC_1	548:552	Mutation altering degron motif	0.5958
p.E1294K	TCGA-CR-5248	HNSC	TCGA	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.1667
p.E1294K	DO14694	HNSC	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.1667
p.T2773I	TCGA-CR-6477	HNSC	TCGA	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation rewiring degron network	0.1111
p.T2773I	DO14216	HNSC	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation rewiring degron network	0.1111
p.V1487I	TCGA-CR-7370	HNSC	TCGA	AVSSS	DEG_SPOP_SBC_1	1491:1495	Mutation rewiring degron network	0.2222
p.V1487I	DO14426	HNSC	ICGC	AVSSS	DEG_SPOP_SBC_1	1491:1495	Mutation rewiring degron network	0.2222
p.P3469L	TCGA-CR-7376	HNSC	TCGA	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.3056
p.P3469L	DO15455	HNSC	ICGC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.3056
p.P3469L	SIDM00451	T-Lymphoblastic Leukemia	GDSC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.3056
p.E645Q	TCGA-CV-6936	HNSC	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.2222
p.E645Q	DO14210	HNSC	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.2222
p.T947S	TCGA-CV-7178	HNSC	TCGA	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation altering degron motif	0.7116
p.T947S	TCGA-RB-AA9M	PAAD	TCGA	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation altering degron motif	0.7116
p.T947S	DO14774	HNSC	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation altering degron motif	0.7116
p.T947S	DO51718	PAAD	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation altering degron motif	0.7116
p.A2847V	TCGA-CV-7568	HNSC	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.A2847V	TCGA-CV-7568	HNSC	TCGA	VDTST	DEG_SPOP_SBC_1	2835:2839	Mutation rewiring degron network	0.1111
p.A2847V	TCGA-CV-7568	HNSC	TCGA	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation rewiring degron network	0.25
p.A2847V	DO14160	HNSC	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.A2847V	DO14160	HNSC	ICGC	VDTST	DEG_SPOP_SBC_1	2835:2839	Mutation rewiring degron network	0.1111
p.A2847V	DO14160	HNSC	ICGC	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation rewiring degron network	0.25
p.G4020D	TCGA-CV-7568	HNSC	TCGA	PSTPRTT	DEG_SCF_FBW7_1	4011:4017	Mutation rewiring degron network	0.25
p.G4020D	TCGA-CV-7568	HNSC	TCGA	PRTTS	DEG_SPOP_SBC_1	4014:4018	Mutation rewiring degron network	0.2778
p.G4020D	DO14160	HNSC	ICGC	PSTPRTT	DEG_SCF_FBW7_1	4011:4017	Mutation rewiring degron network	0.25
p.G4020D	DO14160	HNSC	ICGC	PRTTS	DEG_SPOP_SBC_1	4014:4018	Mutation rewiring degron network	0.2778
p.R279S	TCGA-CV-A45W	HNSC	TCGA	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation altering degron motif	0.7427
p.R279S	DO52060	HNSC	ICGC	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation altering degron motif	0.7427
p.T1541N	TCGA-CV-A45W	HNSC	TCGA	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.7055
p.T1541N	TCGA-CV-A45W	HNSC	TCGA	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.7055
p.T1541N	DO52060	HNSC	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.7055
p.T1541N	DO52060	HNSC	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.7055
p.S467Y	TCGA-D1-A103	UCEC	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation rewiring degron network	0.3056
p.S467Y	TCGA-D1-A103	UCEC	TCGA	PVSTT	DEG_SPOP_SBC_1	458:462	Mutation rewiring degron network	0.1944
p.S467Y	DO42312	UCEC	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation rewiring degron network	0.3056
p.S467Y	DO42312	UCEC	ICGC	PVSTT	DEG_SPOP_SBC_1	458:462	Mutation rewiring degron network	0.1944
p.S1611I	TCGA-D1-A103	UCEC	TCGA	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation altering degron motif	0.623
p.S1611I	DO42312	UCEC	ICGC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation altering degron motif	0.623
p.P3700L	TCGA-D1-A16X	UCEC	TCGA	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation altering degron motif	0.7582
p.P3700L	DO41799	UCEC	ICGC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation altering degron motif	0.7582
p.P2244H	TCGA-D1-A17Q	UCEC	TCGA	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation altering degron motif	0.7694
p.P2244H	DO41903	UCEC	ICGC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation altering degron motif	0.7694
p.T3721I	TCGA-D3-A2J8	SKCM	TCGA	VTSTPVTT	DEG_SCF_FBW7_1	3720:3727	Mutation altering degron motif	0.5966
p.T3721I	DO37778	SKCM	ICGC	VTSTPVTT	DEG_SCF_FBW7_1	3720:3727	Mutation altering degron motif	0.5966
p.E3632K	TCGA-D3-A2JH	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	3641:3645	Mutation rewiring degron network	0.0833
p.E3632K	DO220911	MELA	ICGC	PVSTT	DEG_SPOP_SBC_1	3641:3645	Mutation rewiring degron network	0.0833
p.E3632K	DO47263	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	3641:3645	Mutation rewiring degron network	0.0833
p.S1837N	TCGA-D3-A2JK	SKCM	TCGA	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.S1837N	DO37619	SKCM	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T3225I	TCGA-D3-A51R	SKCM	TCGA	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation altering degron motif	0.5966
p.T3225I	DO47480	SKCM	ICGC	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation altering degron motif	0.5966
p.G4137R	TCGA-D3-A51R	SKCM	TCGA	PRTTT	DEG_SPOP_SBC_1	4130:4134	Mutation rewiring degron network	0.25
p.G4137R	TCGA-E7-A4IJ	BLCA	TCGA	PRTTT	DEG_SPOP_SBC_1	4130:4134	Mutation rewiring degron network	0.25
p.G4137R	DO453	BLCA	ICGC	PRTTT	DEG_SPOP_SBC_1	4130:4134	Mutation rewiring degron network	0.25
p.G4137R	DO47480	SKCM	ICGC	PRTTT	DEG_SPOP_SBC_1	4130:4134	Mutation rewiring degron network	0.25
p.L1534F	TCGA-D3-A8GC	SKCM	TCGA	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.6981
p.L1534F	DO50281	SKCM	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.6981
p.G1335E	TCGA-D3-A8GI	SKCM	TCGA	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.6087
p.G1335E	TCGA-W3-AA1V	SKCM	TCGA	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.6087
p.G1335E	DO50284	SKCM	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.6087
p.G1335E	DO51276	SKCM	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.6087
p.S2890L	TCGA-D3-A8GI	SKCM	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.1389
p.S2890L	DO50284	SKCM	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.1389
p.N3972S	TCGA-D3-A8GI	SKCM	TCGA	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation altering degron motif	0.5958
p.N3972S	DO50284	SKCM	ICGC	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation altering degron motif	0.5958
p.G2100E	TCGA-D3-A8GM	SKCM	TCGA	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.0833
p.G2100E	TCGA-D3-A8GM	SKCM	TCGA	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1111
p.G2100E	DO50288	SKCM	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.0833
p.G2100E	DO50288	SKCM	ICGC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1111
p.E1137K	TCGA-D3-A8GV	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.2778
p.E1137K	TCGA-EE-A3AC	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.2778
p.E1137K	TCGA-GN-A266	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.2778
p.E1137K	DO37631	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.2778
p.E1137K	DO37432	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.2778
p.E1137K	DO219477	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.2778
p.S2101N	TCGA-D6-6516	HNSC	TCGA	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.1111
p.S2101N	TCGA-D6-6516	HNSC	TCGA	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1389
p.S2101N	DO15623	HNSC	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.1111
p.S2101N	DO15623	HNSC	ICGC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1389
p.T3313N	TCGA-D7-5579	STAD	TCGA	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.1944
p.T3313N	TCGA-D7-5579	STAD	TCGA	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation rewiring degron network	0.25
p.T3313N	DO38571	STAD	ICGC	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.1944
p.T3313N	DO38571	STAD	ICGC	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation rewiring degron network	0.25
p.P1760L	TCGA-D7-A4YV	STAD	TCGA	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation altering degron motif	0.7582
p.P1760L	DO47777	STAD	ICGC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation altering degron motif	0.7582
p.P3423H	TCGA-D7-A4YV	STAD	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.0556
p.P3423H	TCGA-D7-A4YV	STAD	TCGA	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.1389
p.P3423H	DO47777	STAD	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.0556
p.P3423H	DO47777	STAD	ICGC	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.1389
p.S3986L	TCGA-D8-A1JA	BRCA	TCGA	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation rewiring degron network	0.0833
p.S3986L	TCGA-D8-A1JA	BRCA	TCGA	PSTSS	DEG_SPOP_SBC_1	3974:3978	Mutation rewiring degron network	0.1111
p.S3986L	TCGA-WE-A8K1	SKCM	TCGA	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation rewiring degron network	0.0833
p.S3986L	TCGA-WE-A8K1	SKCM	TCGA	PSTSS	DEG_SPOP_SBC_1	3974:3978	Mutation rewiring degron network	0.1111
p.S3986L	DO2819	BRCA	ICGC	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation rewiring degron network	0.0833
p.S3986L	DO2819	BRCA	ICGC	PSTSS	DEG_SPOP_SBC_1	3974:3978	Mutation rewiring degron network	0.1111
p.S3986L	DO220891	MELA	ICGC	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation rewiring degron network	0.0833
p.S3986L	DO220891	MELA	ICGC	PSTSS	DEG_SPOP_SBC_1	3974:3978	Mutation rewiring degron network	0.1111
p.S3986L	DO51280	SKCM	ICGC	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation rewiring degron network	0.0833
p.S3986L	DO51280	SKCM	ICGC	PSTSS	DEG_SPOP_SBC_1	3974:3978	Mutation rewiring degron network	0.1111
p.E4087Q	TCGA-D8-A1JA	BRCA	TCGA	ASSTT	DEG_SPOP_SBC_1	4079:4083	Mutation rewiring degron network	0.2222
p.E4087Q	DO2819	BRCA	ICGC	ASSTT	DEG_SPOP_SBC_1	4079:4083	Mutation rewiring degron network	0.2222
p.V2245I	TCGA-D8-A1XQ	BRCA	TCGA	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation altering degron motif	0.5965
p.V2245I	DO3095	BRCA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation altering degron motif	0.5965
p.A2528V	TCGA-D8-A1XQ	BRCA	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation altering degron motif	0.5825
p.A2528V	DO3095	BRCA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation altering degron motif	0.5825
p.L2122F	TCGA-D9-A6EA	SKCM	TCGA	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.1667
p.L2122F	TCGA-D9-A6EA	SKCM	TCGA	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.0556
p.L2122F	DO50290	SKCM	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.1667
p.L2122F	DO50290	SKCM	ICGC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.0556
p.I304F	TCGA-D9-A6EC	SKCM	TCGA	LSTTPAAT	DEG_SCF_FBW7_1	295:302	Mutation rewiring degron network	0.2778
p.I304F	TCGA-D9-A6EC	SKCM	TCGA	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.2778
p.I304F	DO50291	SKCM	ICGC	LSTTPAAT	DEG_SCF_FBW7_1	295:302	Mutation rewiring degron network	0.2778
p.I304F	DO50291	SKCM	ICGC	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.2778
p.T3105A	TCGA-D9-A6EC	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	3111:3115	Mutation rewiring degron network	0.1667
p.T3105A	DO50291	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	3111:3115	Mutation rewiring degron network	0.1667
p.S3709F	TCGA-DA-A1HV	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.1944
p.S3709F	DO37659	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.1944
p.T3214A	TCGA-DA-A1HY	SKCM	TCGA	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.1389
p.T3214A	TCGA-DA-A1HY	SKCM	TCGA	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.0833
p.T3214A	DO37409	SKCM	ICGC	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.1389
p.T3214A	DO37409	SKCM	ICGC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.0833
p.A595T	TCGA-DA-A95V	SKCM	TCGA	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation rewiring degron network	0.2222
p.A595T	TCGA-DA-A95V	SKCM	TCGA	VTTSS	DEG_SPOP_SBC_1	601:605	Mutation rewiring degron network	0.1667
p.A595T	DO219478	SKCM	ICGC	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation rewiring degron network	0.2222
p.A595T	DO219478	SKCM	ICGC	VTTSS	DEG_SPOP_SBC_1	601:605	Mutation rewiring degron network	0.1667
p.T1325S	TCGA-DA-A95Z	SKCM	TCGA	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.0556
p.T1325S	DO219481	SKCM	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.0556
p.E1393K	TCGA-DA-A95Z	SKCM	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.0556
p.E1393K	TCGA-DA-A95Z	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.0833
p.E1393K	TCGA-FR-A8YE	SKCM	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.0556
p.E1393K	TCGA-FR-A8YE	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.0833
p.E1393K	DO229459	SKCA	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.0556
p.E1393K	DO229459	SKCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.0833
p.E1393K	DO50303	SKCM	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.0556
p.E1393K	DO50303	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.0833
p.E1393K	DO219481	SKCM	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.0556
p.E1393K	DO219481	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.0833
p.S3145C	TCGA-DA-A95Z	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.1667
p.S3145C	DO219481	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.1667
p.M2349T	TCGA-DD-AACF	LIHC	TCGA	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.0833
p.M2349T	TCGA-DD-AACF	LIHC	TCGA	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.3056
p.M2349T	DO52201	LIHC	ICGC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.0833
p.M2349T	DO52201	LIHC	ICGC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.3056
p.D3366N	TCGA-DF-A2KN	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation rewiring degron network	0.2222
p.D3366N	DO223282	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation rewiring degron network	0.2222
p.P3974S	TCGA-DF-A2KN	UCEC	TCGA	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation altering degron motif	0.6752
p.P3974S	TCGA-DF-A2KN	UCEC	TCGA	PSTSS	DEG_SPOP_SBC_1	3974:3978	Mutation altering degron motif	0.6752
p.P3974S	DO218840	SKCA	ICGC	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation altering degron motif	0.6752
p.P3974S	DO218840	SKCA	ICGC	PSTSS	DEG_SPOP_SBC_1	3974:3978	Mutation altering degron motif	0.6752
p.P3974S	DO223282	UCEC	ICGC	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation altering degron motif	0.6752
p.P3974S	DO223282	UCEC	ICGC	PSTSS	DEG_SPOP_SBC_1	3974:3978	Mutation altering degron motif	0.6752
p.P679L	TCGA-DF-A2KU	UCEC	TCGA	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.0833
p.P679L	DO222815	BTCA	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.0833
p.P679L	DO223286	UCEC	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.0833
p.P1125H	TCGA-DF-A2KU	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.1667
p.P1125H	DO223286	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.1667
p.S1905G	TCGA-DI-A1BU	UCEC	TCGA	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.0833
p.S1905G	DO42023	UCEC	ICGC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.0833
p.S880Y	TCGA-DK-A2I1	BLCA	TCGA	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.0833
p.S880Y	DO444	BLCA	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.0833
p.V1362A	TCGA-DK-A3IL	BLCA	TCGA	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.1944
p.V1362A	DO555	BLCA	ICGC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.1944
p.S1724C	TCGA-DK-A3IT	BLCA	TCGA	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation altering degron motif	0.7541
p.S1724C	DO779	BLCA	ICGC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation altering degron motif	0.7541
p.S355L	TCGA-DK-A6B2	BLCA	TCGA	VTTST	DEG_SPOP_SBC_1	365:369	Mutation rewiring degron network	0.0556
p.S355L	DO48543	BLCA	ICGC	VTTST	DEG_SPOP_SBC_1	365:369	Mutation rewiring degron network	0.0556
p.T3409M	TCGA-DM-A28K	COAD	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation altering degron motif	0.7423
p.T3409M	TCGA-E9-A1NC	BRCA	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation altering degron motif	0.7423
p.T3409M	DO8167	COAD	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation altering degron motif	0.7423
p.T3409M	SIDM00052	Esophageal Squamous Cell Carcinoma	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation altering degron motif	0.7423
p.T3409M	HCE-4	oesophagus	COSMIC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation altering degron motif	0.7423
p.L3738V	TCGA-DR-A0ZM	CESC	TCGA	PVTTS	DEG_SPOP_SBC_1	3724:3728	Mutation rewiring degron network	0.0556
p.L3738V	TCGA-DR-A0ZM	CESC	TCGA	AISSS	DEG_SPOP_SBC_1	3731:3735	Mutation rewiring degron network	0.25
p.L3738V	DO6254	CESC	ICGC	PVTTS	DEG_SPOP_SBC_1	3724:3728	Mutation rewiring degron network	0.0556
p.L3738V	DO6254	CESC	ICGC	AISSS	DEG_SPOP_SBC_1	3731:3735	Mutation rewiring degron network	0.25
p.P4047S	TCGA-DS-A1OB	CESC	TCGA	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation altering degron motif	0.6752
p.P4047S	DO6323	CESC	ICGC	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation altering degron motif	0.6752
p.E2551K	TCGA-DS-A1OD	CESC	TCGA	VVTST	DEG_SPOP_SBC_1	2546:2550	Mutation rewiring degron network	0.3056
p.E2551K	DO6299	CESC	ICGC	VVTST	DEG_SPOP_SBC_1	2546:2550	Mutation rewiring degron network	0.3056
p.P965S	TCGA-DU-6392	LGG	TCGA	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.1389
p.P965S	TCGA-EE-A29E	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.1389
p.P965S	DO22237	LGG	ICGC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.1389
p.P965S	DO37831	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.1389
p.S2165N	TCGA-DU-6392	LGG	TCGA	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.2778
p.S2165N	DO22237	LGG	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.2778
p.E2531D	TCGA-DU-6392	LGG	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation rewiring degron network	0.2778
p.E2531D	TCGA-DU-6392	LGG	TCGA	PVSTT	DEG_SPOP_SBC_1	2521:2525	Mutation rewiring degron network	0.1667
p.E2531D	DO22237	LGG	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation rewiring degron network	0.2778
p.E2531D	DO22237	LGG	ICGC	PVSTT	DEG_SPOP_SBC_1	2521:2525	Mutation rewiring degron network	0.1667
p.V3406I	TCGA-DU-6392	LGG	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation altering degron motif	0.5965
p.V3406I	DO22237	LGG	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation altering degron motif	0.5965
p.D1716E	TCGA-DU-6396	LGG	TCGA	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.2222
p.D1716E	DO22143	LGG	ICGC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.2222
p.P3047S	TCGA-DU-6407	LGG	TCGA	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.1944
p.P3047S	DO22295	LGG	ICGC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.1944
p.P3106S	TCGA-DU-6407	LGG	TCGA	PVSTT	DEG_SPOP_SBC_1	3111:3115	Mutation rewiring degron network	0.1944
p.P3106S	DO22295	LGG	ICGC	PVSTT	DEG_SPOP_SBC_1	3111:3115	Mutation rewiring degron network	0.1944
p.P1538A	TCGA-DU-7007	LGG	TCGA	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.7503
p.P1538A	DO22400	LGG	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.7503
p.T2456N	TCGA-DX-A3U5	SARC	TCGA	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1667
p.T2456N	DO219972	SARC	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1667
p.L3125F	TCGA-DX-A8BP	SARC	TCGA	PVSTT	DEG_SPOP_SBC_1	3111:3115	Mutation rewiring degron network	0.0556
p.L3125F	TCGA-DX-A8BP	SARC	TCGA	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.0556
p.L3125F	DO220056	SARC	ICGC	PVSTT	DEG_SPOP_SBC_1	3111:3115	Mutation rewiring degron network	0.0556
p.L3125F	DO220056	SARC	ICGC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.0556
p.S1645I	TCGA-DX-A8BT	SARC	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation altering degron motif	0.7341
p.S1645I	DO220063	SARC	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation altering degron motif	0.7341
p.S1645I	SIDM00231	Kidney Carcinoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation altering degron motif	0.7341
p.S1645I	NCC010	kidney	COSMIC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation altering degron motif	0.7341
p.S2116I	TCGA-DX-AB2O	SARC	TCGA	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.7341
p.S2116I	DO220083	SARC	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.7341
p.P866S	TCGA-E6-A1LX	UCEC	TCGA	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation altering degron motif	0.5641
p.P866S	DO41020	UCEC	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation altering degron motif	0.5641
p.A1374S	TCGA-E6-A1LX	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.25
p.A1374S	DO41020	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.25
p.P1773H	TCGA-E6-A1LX	UCEC	TCGA	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation altering degron motif	0.7694
p.P1773H	DO41020	UCEC	ICGC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation altering degron motif	0.7694
p.L1887R	TCGA-E6-A1LX	UCEC	TCGA	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1944
p.L1887R	DO41020	UCEC	ICGC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1944
p.S2078Y	TCGA-E6-A1LX	UCEC	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation rewiring degron network	0.1389
p.S2078Y	DO41020	UCEC	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation rewiring degron network	0.1389
p.S3144P	TCGA-E6-A1LX	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.1944
p.S3144P	DO41020	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.1944
p.L3478F	TCGA-E6-A1LX	UCEC	TCGA	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.0556
p.L3478F	DO41020	UCEC	ICGC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.0556
p.S3949Y	TCGA-E6-A1LX	UCEC	TCGA	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation altering degron motif	0.712
p.S3949Y	DO41020	UCEC	ICGC	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation altering degron motif	0.712
p.P4486H	TCGA-E6-A1LX	UCEC	TCGA	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation rewiring degron network	0.2778
p.P4486H	DO41020	UCEC	ICGC	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation rewiring degron network	0.2778
p.A3059G	TCGA-E7-A4IJ	BLCA	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.1389
p.A3059G	TCGA-E7-A4IJ	BLCA	TCGA	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.25
p.A3059G	DO453	BLCA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.1389
p.A3059G	DO453	BLCA	ICGC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.25
p.S3299G	TCGA-E7-A4IJ	BLCA	TCGA	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.2778
p.S3299G	TCGA-E7-A4IJ	BLCA	TCGA	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.1111
p.S3299G	TCGA-E7-A4IJ	BLCA	TCGA	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation rewiring degron network	0.1389
p.S3299G	DO453	BLCA	ICGC	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.2778
p.S3299G	DO453	BLCA	ICGC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.1111
p.S3299G	DO453	BLCA	ICGC	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation rewiring degron network	0.1389
p.T530A	TCGA-E7-A541	BLCA	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation rewiring degron network	0.3056
p.T530A	TCGA-E7-A541	BLCA	TCGA	VDTST	DEG_SPOP_SBC_1	536:540	Mutation rewiring degron network	0.1667
p.T530A	DO44037	BLCA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation rewiring degron network	0.3056
p.T530A	DO44037	BLCA	ICGC	VDTST	DEG_SPOP_SBC_1	536:540	Mutation rewiring degron network	0.1667
p.E2512K	TCGA-E7-A541	BLCA	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation rewiring degron network	0.0556
p.E2512K	TCGA-E7-A541	BLCA	TCGA	PVSTT	DEG_SPOP_SBC_1	2521:2525	Mutation rewiring degron network	0.0833
p.E2512K	DO44037	BLCA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation rewiring degron network	0.0556
p.E2512K	DO44037	BLCA	ICGC	PVSTT	DEG_SPOP_SBC_1	2521:2525	Mutation rewiring degron network	0.0833
p.S1729L	TCGA-EB-A431	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.1944
p.S1729L	TCGA-FW-A3R5	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.1944
p.S1729L	DO37671	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.1944
p.S1729L	DO37406	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.1944
p.S2849L	TCGA-EB-A4XL	SKCM	TCGA	VDTST	DEG_SPOP_SBC_1	2835:2839	Mutation rewiring degron network	0.0556
p.S2849L	TCGA-EB-A4XL	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation rewiring degron network	0.1944
p.S2849L	DO47401	SKCM	ICGC	VDTST	DEG_SPOP_SBC_1	2835:2839	Mutation rewiring degron network	0.0556
p.S2849L	DO47401	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation rewiring degron network	0.1944
p.S1258F	TCGA-EB-A5UL	SKCM	TCGA	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation altering degron motif	0.7982
p.S1258F	DO222662	MELA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation altering degron motif	0.7982
p.S1258F	DO47601	SKCM	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation altering degron motif	0.7982
p.V582M	TCGA-ED-A7PZ	LIHC	TCGA	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation rewiring degron network	0.1944
p.V582M	DO48532	LIHC	ICGC	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation rewiring degron network	0.1944
p.T3431I	TCGA-ED-A7PZ	LIHC	TCGA	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation altering degron motif	0.5966
p.T3431I	DO48532	LIHC	ICGC	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation altering degron motif	0.5966
p.G1394E	TCGA-EE-A181	SKCM	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.0833
p.G1394E	TCGA-EE-A181	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1111
p.G1394E	TCGA-W3-A825	SKCM	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.0833
p.G1394E	TCGA-W3-A825	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1111
p.G1394E	DO37444	SKCM	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.0833
p.G1394E	DO37444	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1111
p.G1394E	DO51272	SKCM	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.0833
p.G1394E	DO51272	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1111
p.S3734F	TCGA-EE-A182	SKCM	TCGA	AISSS	DEG_SPOP_SBC_1	3731:3735	Mutation altering degron motif	0.7982
p.S3734F	DO37814	SKCM	ICGC	AISSS	DEG_SPOP_SBC_1	3731:3735	Mutation altering degron motif	0.7982
p.D3131N	TCGA-EE-A183	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.2222
p.D3131N	DO37715	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.2222
p.T3967A	TCGA-EE-A20C	SKCM	TCGA	VSTPVIT	DEG_SCF_FBW7_1	3961:3967	Mutation altering degron motif	0.7139
p.T3967A	TCGA-EE-A20C	SKCM	TCGA	VITST	DEG_SPOP_SBC_1	3965:3969	Mutation altering degron motif	0.7139
p.T3967A	DO222775	MELA	ICGC	VSTPVIT	DEG_SCF_FBW7_1	3961:3967	Mutation altering degron motif	0.7139
p.T3967A	DO222775	MELA	ICGC	VITST	DEG_SPOP_SBC_1	3965:3969	Mutation altering degron motif	0.7139
p.T3967A	DO47665	SKCM	ICGC	VSTPVIT	DEG_SCF_FBW7_1	3961:3967	Mutation altering degron motif	0.7139
p.T3967A	DO47665	SKCM	ICGC	VITST	DEG_SPOP_SBC_1	3965:3969	Mutation altering degron motif	0.7139
p.E1255K	TCGA-EE-A29B	SKCM	TCGA	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation altering degron motif	0.591
p.E1255K	DO47255	SKCM	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation altering degron motif	0.591
p.G1629E	TCGA-EE-A29M	SKCM	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation rewiring degron network	0.0833
p.G1629E	DO37404	SKCM	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation rewiring degron network	0.0833
p.A3475T	TCGA-EE-A29M	SKCM	TCGA	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.1389
p.A3475T	DO37404	SKCM	ICGC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.1389
p.E409K	TCGA-EE-A2A0	SKCM	TCGA	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation rewiring degron network	0.3056
p.E409K	DO11854	GBM	ICGC	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation rewiring degron network	0.3056
p.E409K	DO37439	SKCM	ICGC	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation rewiring degron network	0.3056
p.P1637L	TCGA-EE-A2A0	SKCM	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation rewiring degron network	0.3056
p.P1637L	DO37439	SKCM	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation rewiring degron network	0.3056
p.P653S	TCGA-EE-A2A2	SKCM	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation altering degron motif	0.6752
p.P653S	DO37583	SKCM	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation altering degron motif	0.6752
p.S1436F	TCGA-EE-A2GB	SKCM	TCGA	PGTTS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.1667
p.S1436F	DO222683	MELA	ICGC	PGTTS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.1667
p.S1436F	DO37417	SKCM	ICGC	PGTTS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.1667
p.S420F	TCGA-EE-A2GC	SKCM	TCGA	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation rewiring degron network	0.1667
p.S420F	DO37839	SKCM	ICGC	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation rewiring degron network	0.1667
p.P1691S	TCGA-EE-A2GC	SKCM	TCGA	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.5641
p.P1691S	TCGA-QB-AA9O	SKCM	TCGA	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.5641
p.P1691S	DO37839	SKCM	ICGC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.5641
p.P1691S	DO51267	SKCM	ICGC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.5641
p.S1847L	TCGA-EE-A2GI	SKCM	TCGA	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation altering degron motif	0.7667
p.S1847L	TCGA-GN-A8LN	SKCM	TCGA	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation altering degron motif	0.7667
p.S1847L	DO37410	SKCM	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation altering degron motif	0.7667
p.S1847L	DO51262	SKCM	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation altering degron motif	0.7667
p.G2867E	TCGA-EE-A2GI	SKCM	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.0833
p.G2867E	DO37410	SKCM	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.0833
p.P1284L	TCGA-EE-A2GJ	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation altering degron motif	0.7582
p.P1284L	DO37746	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation altering degron motif	0.7582
p.T1252P	TCGA-EE-A2GP	SKCM	TCGA	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.2778
p.T1252P	DO37422	SKCM	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.2778
p.T1252P	ACH-000945	Lung Cancer	CCLE	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.2778
p.T1252P	NCI-H650	lung	COSMIC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.2778
p.P3076L	TCGA-EE-A2GR	SKCM	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.25
p.P3076L	DO37996	SKCM	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.25
p.E4050K	TCGA-EE-A2GR	SKCM	TCGA	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation altering degron motif	0.7022
p.E4050K	DO222662	MELA	ICGC	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation altering degron motif	0.7022
p.E4050K	DO37996	SKCM	ICGC	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation altering degron motif	0.7022
p.E4478K	TCGA-EE-A2M6	SKCM	TCGA	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation rewiring degron network	0.0556
p.E4478K	DO222514	MELA	ICGC	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation rewiring degron network	0.0556
p.E4478K	DO37976	SKCM	ICGC	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation rewiring degron network	0.0556
p.P1161S	TCGA-EE-A2MG	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1944
p.P1161S	DO37421	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1944
p.E606K	TCGA-EE-A2MJ	SKCM	TCGA	VTTSS	DEG_SPOP_SBC_1	601:605	Mutation rewiring degron network	0.3056
p.E606K	TCGA-EE-A2MJ	SKCM	TCGA	ASSSS	DEG_SPOP_SBC_1	607:611	Mutation rewiring degron network	0.3056
p.E606K	DO38099	SKCM	ICGC	VTTSS	DEG_SPOP_SBC_1	601:605	Mutation rewiring degron network	0.3056
p.E606K	DO38099	SKCM	ICGC	ASSSS	DEG_SPOP_SBC_1	607:611	Mutation rewiring degron network	0.3056
p.E143K	TCGA-EE-A2MR	SKCM	TCGA	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation rewiring degron network	0.1944
p.E143K	DO37819	SKCM	ICGC	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation rewiring degron network	0.1944
p.T661I	TCGA-EE-A2MR	SKCM	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.1944
p.T661I	TCGA-EE-A2MR	SKCM	TCGA	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.1944
p.T661I	DO37819	SKCM	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.1944
p.T661I	DO37819	SKCM	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.1944
p.P2045S	TCGA-EE-A2MR	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.1944
p.P2045S	DO37819	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.1944
p.T2475I	TCGA-EE-A2MR	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.0833
p.T2475I	DO37819	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.0833
p.E3811K	TCGA-EE-A2MR	SKCM	TCGA	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.2778
p.E3811K	TCGA-FR-A7U9	SKCM	TCGA	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.2778
p.E3811K	DO222632	MELA	ICGC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.2778
p.E3811K	DO222702	MELA	ICGC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.2778
p.E3811K	DO48546	SKCM	ICGC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.2778
p.E3811K	DO37819	SKCM	ICGC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.2778
p.S1081L	TCGA-EE-A2MS	SKCM	TCGA	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation altering degron motif	0.7667
p.S1081L	DO37567	SKCM	ICGC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation altering degron motif	0.7667
p.G3220E	TCGA-EE-A2MS	SKCM	TCGA	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.3056
p.G3220E	DO37567	SKCM	ICGC	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.3056
p.E645K	TCGA-EE-A3AE	SKCM	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.2222
p.E645K	DO37802	SKCM	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.2222
p.E645K	SIDM00562	Breast Carcinoma	GDSC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.2222
p.E645K	ACH-002163	Breast Cancer	CCLE	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.2222
p.E645K	MRK-nu-1	breast	COSMIC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.2222
p.P2834L	TCGA-EE-A3AE	SKCM	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation altering degron motif	0.7582
p.P2834L	DO37802	SKCM	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation altering degron motif	0.7582
p.P2244S	TCGA-EE-A3AF	SKCM	TCGA	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation altering degron motif	0.6752
p.P2244S	DO37911	SKCM	ICGC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation altering degron motif	0.6752
p.P4123L	TCGA-EE-A3AF	SKCM	TCGA	PRTTT	DEG_SPOP_SBC_1	4130:4134	Mutation rewiring degron network	0.1389
p.P4123L	DO37911	SKCM	ICGC	PRTTT	DEG_SPOP_SBC_1	4130:4134	Mutation rewiring degron network	0.1389
p.G1747E	TCGA-EE-A3AG	SKCM	TCGA	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation rewiring degron network	0.0833
p.G1747E	TCGA-EE-A3AG	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.1111
p.G1747E	DO37471	SKCM	ICGC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation rewiring degron network	0.0833
p.G1747E	DO37471	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.1111
p.D3072Y	TCGA-EE-A3AH	SKCM	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation altering degron motif	0.6214
p.D3072Y	DO222635	MELA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation altering degron motif	0.6214
p.D3072Y	DO37443	SKCM	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation altering degron motif	0.6214
p.P3464L	TCGA-EE-A3J4	SKCM	TCGA	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation altering degron motif	0.7582
p.P3464L	DO48604	SKCM	ICGC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation altering degron motif	0.7582
p.P2339L	TCGA-EE-A3J5	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1944
p.P2339L	DO222644	MELA	ICGC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1944
p.P2339L	DO47331	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1944
p.S2110I	TCGA-EE-A3JD	SKCM	TCGA	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.623
p.S2110I	TCGA-EE-A3JD	SKCM	TCGA	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation altering degron motif	0.7341
p.S2110I	DO50299	SKCM	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.623
p.S2110I	DO50299	SKCM	ICGC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation altering degron motif	0.7341
p.S2110R	TCGA-EE-A3JD	SKCM	TCGA	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.6316
p.S2110R	TCGA-EE-A3JD	SKCM	TCGA	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation altering degron motif	0.7427
p.S2110R	TCGA-L9-A743	LUAD	TCGA	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.6316
p.S2110R	TCGA-L9-A743	LUAD	TCGA	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation altering degron motif	0.7427
p.S2110R	DO49874	LUAD	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.6316
p.S2110R	DO49874	LUAD	ICGC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation altering degron motif	0.7427
p.S2110R	DO50299	SKCM	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.6316
p.S2110R	DO50299	SKCM	ICGC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation altering degron motif	0.7427
p.A1263V	TCGA-EJ-7218	PRAD	TCGA	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1944
p.A1263V	TCGA-EJ-7218	PRAD	TCGA	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.1667
p.A1263V	DO51310	PRAD	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1944
p.A1263V	DO51310	PRAD	ICGC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.1667
p.T3539I	TCGA-EJ-7782	PRAD	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation rewiring degron network	0.1111
p.T3539I	TCGA-EJ-7782	PRAD	TCGA	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.0833
p.T3539I	DO36256	PRAD	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation rewiring degron network	0.1111
p.T3539I	DO36256	PRAD	ICGC	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.0833
p.T3539I	SIDM00660	Colorectal Carcinoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation rewiring degron network	0.1111
p.T3539I	SIDM00660	Colorectal Carcinoma	GDSC	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.0833
p.T3539I	ACH-000985	Colon/Colorectal Cancer	CCLE	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation rewiring degron network	0.1111
p.T3539I	ACH-000985	Colon/Colorectal Cancer	CCLE	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.0833
p.T3539I	LS-411N	large intestine	COSMIC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation rewiring degron network	0.1111
p.T3539I	LS-411N	large intestine	COSMIC	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.0833
p.A1703T	TCGA-EM-A22O	THCA	TCGA	VRTTPVAS	DEG_SCF_FBW7_1	1697:1704	Mutation altering degron motif	0.6028
p.A1703T	DO38911	THCA	ICGC	VRTTPVAS	DEG_SCF_FBW7_1	1697:1704	Mutation altering degron motif	0.6028
p.I1774V	TCGA-EM-A22Q	THCA	TCGA	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation altering degron motif	0.5965
p.I1774V	DO40141	THCA	ICGC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation altering degron motif	0.5965
p.N303S	TCGA-EM-A2P0	THCA	TCGA	LSTTPAAT	DEG_SCF_FBW7_1	295:302	Mutation rewiring degron network	0.3056
p.N303S	TCGA-EM-A2P0	THCA	TCGA	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.25
p.N303S	DO39622	THCA	ICGC	LSTTPAAT	DEG_SCF_FBW7_1	295:302	Mutation rewiring degron network	0.3056
p.N303S	DO39622	THCA	ICGC	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.25
p.S1129I	TCGA-EO-A22R	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.2778
p.S1129I	DO42713	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.2778
p.T4143M	TCGA-EO-A22R	UCEC	TCGA	PRTTT	DEG_SPOP_SBC_1	4130:4134	Mutation rewiring degron network	0.0833
p.T4143M	DO42713	UCEC	ICGC	PRTTT	DEG_SPOP_SBC_1	4130:4134	Mutation rewiring degron network	0.0833
p.A1606T	TCGA-EO-A22U	UCEC	TCGA	LSTTPIDS	DEG_SCF_FBW7_1	1593:1600	Mutation rewiring degron network	0.1667
p.A1606T	TCGA-EO-A22U	UCEC	TCGA	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.2222
p.A1606T	DO43755	UCEC	ICGC	LSTTPIDS	DEG_SCF_FBW7_1	1593:1600	Mutation rewiring degron network	0.1667
p.A1606T	DO43755	UCEC	ICGC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.2222
p.L2181F	TCGA-EO-A22U	UCEC	TCGA	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.0556
p.L2181F	DO43755	UCEC	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.0556
p.L2181F	SIDM00797	Melanoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.0556
p.L2181F	ACH-000788	Skin Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.0556
p.L2181F	A2058	skin	COSMIC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.0556
p.P1701Q	TCGA-EO-A22X	UCEC	TCGA	VRTTPVAS	DEG_SCF_FBW7_1	1697:1704	Mutation altering degron motif	0.7035
p.P1701Q	DO43907	UCEC	ICGC	VRTTPVAS	DEG_SCF_FBW7_1	1697:1704	Mutation altering degron motif	0.7035
p.P1897H	TCGA-EO-A22X	UCEC	TCGA	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.3056
p.P1897H	DO43907	UCEC	ICGC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.3056
p.M2166T	TCGA-EO-A22X	UCEC	TCGA	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.3056
p.M2166T	DO43907	UCEC	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.3056
p.T1372I	TCGA-EO-A3AY	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.3056
p.T1372I	DO43202	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.3056
p.S703Y	TCGA-EO-A3B0	UCEC	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	708:715	Mutation rewiring degron network	0.1944
p.S703Y	TCGA-EO-A3B0	UCEC	TCGA	VDTST	DEG_SPOP_SBC_1	713:717	Mutation rewiring degron network	0.0556
p.S703Y	DO219773	UCEC	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	708:715	Mutation rewiring degron network	0.1944
p.S703Y	DO219773	UCEC	ICGC	VDTST	DEG_SPOP_SBC_1	713:717	Mutation rewiring degron network	0.0556
p.T853A	TCGA-EO-A3B0	UCEC	TCGA	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.0556
p.T853A	DO219773	UCEC	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.0556
p.T1085A	TCGA-EO-A3B0	UCEC	TCGA	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.2778
p.T1085A	DO219773	UCEC	ICGC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.2778
p.T1337P	TCGA-EO-A3B0	UCEC	TCGA	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.5919
p.T1337P	DO219773	UCEC	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.5919
p.P3070H	TCGA-EO-A3B0	UCEC	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation altering degron motif	0.7694
p.P3070H	DO219773	UCEC	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation altering degron motif	0.7694
p.S3733L	TCGA-ER-A195	SKCM	TCGA	AISSS	DEG_SPOP_SBC_1	3731:3735	Mutation altering degron motif	0.7667
p.S3733L	DO47712	SKCM	ICGC	AISSS	DEG_SPOP_SBC_1	3731:3735	Mutation altering degron motif	0.7667
p.E2453K	TCGA-ER-A19A	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.0833
p.E2453K	TCGA-ER-A19K	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.0833
p.E2453K	DO222702	MELA	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.0833
p.E2453K	DO218850	SKCA	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.0833
p.E2453K	DO47425	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.0833
p.E2453K	DO47672	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.0833
p.P1681S	TCGA-ER-A19G	SKCM	TCGA	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation rewiring degron network	0.1389
p.P1681S	DO47284	SKCM	ICGC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation rewiring degron network	0.1389
p.L1593F	TCGA-ER-A2NC	SKCM	TCGA	LSTTPIDS	DEG_SCF_FBW7_1	1593:1600	Mutation altering degron motif	0.6981
p.L1593F	DO47318	SKCM	ICGC	LSTTPIDS	DEG_SCF_FBW7_1	1593:1600	Mutation altering degron motif	0.6981
p.G1088D	TCGA-ER-A3PL	SKCM	TCGA	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.1944
p.G1088D	DO37495	SKCM	ICGC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.1944
p.G1088D	SIDM00189	Melanoma	GDSC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.1944
p.G1088D	ACH-002098	Skin Cancer	CCLE	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.1944
p.G1088D	CP67-MEL	skin	COSMIC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.1944
p.T599N	TCGA-EY-A1G8	UCEC	TCGA	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation rewiring degron network	0.1111
p.T599N	TCGA-EY-A1G8	UCEC	TCGA	VTTSS	DEG_SPOP_SBC_1	601:605	Mutation rewiring degron network	0.2778
p.T599N	TCGA-EY-A1G8	UCEC	TCGA	ASSSS	DEG_SPOP_SBC_1	607:611	Mutation rewiring degron network	0.1111
p.T599N	DO43578	UCEC	ICGC	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation rewiring degron network	0.1111
p.T599N	DO43578	UCEC	ICGC	VTTSS	DEG_SPOP_SBC_1	601:605	Mutation rewiring degron network	0.2778
p.T599N	DO43578	UCEC	ICGC	ASSSS	DEG_SPOP_SBC_1	607:611	Mutation rewiring degron network	0.1111
p.S3149Y	TCGA-EY-A1G8	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.0556
p.S3149Y	DO43578	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.0556
p.R279I	TCGA-EY-A1GI	UCEC	TCGA	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation altering degron motif	0.8102
p.R279I	DO41211	UCEC	ICGC	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation altering degron motif	0.8102
p.S3447I	TCGA-EY-A215	UCEC	TCGA	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.2778
p.S3447I	DO42665	UCEC	ICGC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.2778
p.P3724H	TCGA-EY-A549	UCEC	TCGA	VTSTPVTT	DEG_SCF_FBW7_1	3720:3727	Mutation altering degron motif	0.7694
p.P3724H	TCGA-EY-A549	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	3724:3728	Mutation altering degron motif	0.7694
p.P3724H	DO48174	UCEC	ICGC	VTSTPVTT	DEG_SCF_FBW7_1	3720:3727	Mutation altering degron motif	0.7694
p.P3724H	DO48174	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	3724:3728	Mutation altering degron motif	0.7694
p.T1945A	TCGA-F5-6814	READ	TCGA	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation blocking phosphorylation signal	0.5278
p.T1945A	DO36556	READ	ICGC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation blocking phosphorylation signal	0.5278
p.T186A	TCGA-F7-A624	HNSC	TCGA	MSTPLTT	DEG_SCF_FBW7_1	184:190	Mutation altering degron motif	0.7139
p.T186A	DO44440	HNSC	ICGC	MSTPLTT	DEG_SCF_FBW7_1	184:190	Mutation altering degron motif	0.7139
p.E2531Q	TCGA-FD-A3B3	BLCA	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation rewiring degron network	0.2778
p.E2531Q	TCGA-FD-A3B3	BLCA	TCGA	PVSTT	DEG_SPOP_SBC_1	2521:2525	Mutation rewiring degron network	0.1667
p.E2531Q	DO749	BLCA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation rewiring degron network	0.2778
p.E2531Q	DO749	BLCA	ICGC	PVSTT	DEG_SPOP_SBC_1	2521:2525	Mutation rewiring degron network	0.1667
p.E586D	TCGA-FD-A43P	BLCA	TCGA	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation rewiring degron network	0.3056
p.E586D	DO44049	BLCA	ICGC	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation rewiring degron network	0.3056
p.E586D	DO229018	LICA	ICGC	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation rewiring degron network	0.3056
p.L2103V	TCGA-FD-A5C1	BLCA	TCGA	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.1667
p.L2103V	TCGA-FD-A5C1	BLCA	TCGA	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.L2103V	DO44043	BLCA	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.1667
p.L2103V	DO44043	BLCA	ICGC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.E2885Q	TCGA-FD-A6TC	BLCA	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.2778
p.E2885Q	DO49755	BLCA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.2778
p.P1249L	TCGA-FI-A2D5	UCEC	TCGA	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1944
p.P1249L	DO41331	UCEC	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1944
p.S1542G	TCGA-FI-A2D5	UCEC	TCGA	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.6993
p.S1542G	DO41331	UCEC	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.6993
p.V2822M	TCGA-FI-A2D5	UCEC	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.1111
p.V2822M	DO41331	UCEC	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.1111
p.M3404V	TCGA-FI-A2D5	UCEC	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.2778
p.M3404V	DO41331	UCEC	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.2778
p.S3407N	TCGA-FI-A2D5	UCEC	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation altering degron motif	0.5958
p.S3407N	DO41331	UCEC	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation altering degron motif	0.5958
p.R4019I	TCGA-FI-A2D5	UCEC	TCGA	PSTPRTT	DEG_SCF_FBW7_1	4011:4017	Mutation rewiring degron network	0.2778
p.R4019I	TCGA-FI-A2D5	UCEC	TCGA	PRTTS	DEG_SPOP_SBC_1	4014:4018	Mutation rewiring degron network	0.3056
p.R4019I	DO41331	UCEC	ICGC	PSTPRTT	DEG_SCF_FBW7_1	4011:4017	Mutation rewiring degron network	0.2778
p.R4019I	DO41331	UCEC	ICGC	PRTTS	DEG_SPOP_SBC_1	4014:4018	Mutation rewiring degron network	0.3056
p.T302A	TCGA-FI-A2F4	UCEC	TCGA	LSTTPAAT	DEG_SCF_FBW7_1	295:302	Mutation altering degron motif	0.7139
p.T302A	DO43434	UCEC	ICGC	LSTTPAAT	DEG_SCF_FBW7_1	295:302	Mutation altering degron motif	0.7139
p.S3378N	TCGA-FI-A2F4	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation rewiring degron network	0.2222
p.S3378N	DO43434	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation rewiring degron network	0.2222
p.P476S	TCGA-FR-A726	SKCM	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation rewiring degron network	0.0556
p.P476S	DO48665	SKCM	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation rewiring degron network	0.0556
p.S3361F	TCGA-FR-A726	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation rewiring degron network	0.0833
p.S3361F	DO48665	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation rewiring degron network	0.0833
p.G3692E	TCGA-FR-A726	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.1111
p.G3692E	DO48665	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.1111
p.L1946F	TCGA-FR-A729	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.0556
p.L1946F	DO48618	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.0556
p.L1946F	SIDM00810	Non-Small Cell Lung Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.0556
p.L1946F	ACH-000757	Lung Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.0556
p.L1946F	A427	lung	COSMIC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.0556
p.S283N	TCGA-FR-A7U9	SKCM	TCGA	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation altering degron motif	0.5958
p.S283N	DO48546	SKCM	ICGC	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation altering degron motif	0.5958
p.G1335R	TCGA-FR-A7U9	SKCM	TCGA	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.6457
p.G1335R	DO48546	SKCM	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.6457
p.G1335R	SIDM01059	Melanoma	GDSC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.6457
p.G1335R	ACH-000915	Skin Cancer	CCLE	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.6457
p.G1335R	IPC-298	skin	COSMIC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.6457
p.S3144L	TCGA-FS-A1Z3	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.1944
p.S3144L	DO37635	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.1944
p.S3144L	SIDM01483	Melanoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.1944
p.S3144L	ACH-000582	Skin Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.1944
p.S3144L	COLO-741	large intestine	COSMIC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.1944
p.E3710K	TCGA-FS-A1ZW	SKCM	TCGA	VTSTPVTT	DEG_SCF_FBW7_1	3720:3727	Mutation rewiring degron network	0.0556
p.E3710K	TCGA-FS-A1ZW	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.1667
p.E3710K	DO37519	SKCM	ICGC	VTSTPVTT	DEG_SCF_FBW7_1	3720:3727	Mutation rewiring degron network	0.0556
p.E3710K	DO37519	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.1667
p.P2113S	TCGA-FS-A1ZZ	SKCM	TCGA	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.6752
p.P2113S	DO37412	SKCM	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.6752
p.G1276E	TCGA-FS-A4F8	SKCM	TCGA	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.25
p.G1276E	TCGA-FS-A4F8	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.1111
p.G1276E	DO38117	SKCM	ICGC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.25
p.G1276E	DO38117	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.1111
p.P3129H	TCGA-FU-A40J	CESC	TCGA	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.1667
p.P3129H	DO44314	CESC	ICGC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.1667
p.P187S	TCGA-FW-A3R5	SKCM	TCGA	MSTPLTT	DEG_SCF_FBW7_1	184:190	Mutation altering degron motif	0.6752
p.P187S	TCGA-FW-A3R5	SKCM	TCGA	PLTTS	DEG_SPOP_SBC_1	187:191	Mutation altering degron motif	0.6752
p.P187S	DO37406	SKCM	ICGC	MSTPLTT	DEG_SCF_FBW7_1	184:190	Mutation altering degron motif	0.6752
p.P187S	DO37406	SKCM	ICGC	PLTTS	DEG_SPOP_SBC_1	187:191	Mutation altering degron motif	0.6752
p.E862K	TCGA-FW-A3R5	SKCM	TCGA	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.3056
p.E862K	TCGA-YD-A9TA	SKCM	TCGA	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.3056
p.E862K	DO37406	SKCM	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.3056
p.E862K	DO219503	SKCM	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.3056
p.E862K	SIDM00841	Colorectal Carcinoma	GDSC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.3056
p.E862K	ACH-000651	Colon/Colorectal Cancer	CCLE	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.3056
p.E862K	SW620	large intestine	COSMIC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.3056
p.A1648T	TCGA-FW-A3R5	SKCM	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation rewiring degron network	0.25
p.A1648T	DO37406	SKCM	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation rewiring degron network	0.25
p.P3558S	TCGA-FW-A3R5	SKCM	TCGA	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.1667
p.P3558S	DO37406	SKCM	ICGC	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.1667
p.P3558L	TCGA-FW-A3R5	SKCM	TCGA	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.1667
p.P3558L	DO37406	SKCM	ICGC	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.1667
p.T4033S	TCGA-FW-A3R5	SKCM	TCGA	PHTST	DEG_SPOP_SBC_1	4034:4038	Mutation rewiring degron network	0.3056
p.T4033S	DO37406	SKCM	ICGC	PHTST	DEG_SPOP_SBC_1	4034:4038	Mutation rewiring degron network	0.3056
p.T4033I	TCGA-FW-A3R5	SKCM	TCGA	PHTST	DEG_SPOP_SBC_1	4034:4038	Mutation rewiring degron network	0.3056
p.T4033I	DO37406	SKCM	ICGC	PHTST	DEG_SPOP_SBC_1	4034:4038	Mutation rewiring degron network	0.3056
p.T1340R	TCGA-G2-A2ES	BLCA	TCGA	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.6765
p.T1340R	DO785	BLCA	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.6765
p.S1376L	TCGA-G2-A3IE	BLCA	TCGA	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.1944
p.S1376L	DO767	BLCA	ICGC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.1944
p.V1761I	TCGA-G4-6586	COAD	TCGA	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation altering degron motif	0.5965
p.V1761I	DO9698	COAD	ICGC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation altering degron motif	0.5965
p.P3695S	TCGA-GF-A6C8	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.1944
p.P3695S	DO48765	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.1944
p.S159L	TCGA-GF-A6C9	SKCM	TCGA	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation rewiring degron network	0.2222
p.S159L	DO51254	SKCM	ICGC	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation rewiring degron network	0.2222
p.E2826K	TCGA-GF-A6C9	SKCM	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.2222
p.E2826K	TCGA-GF-A6C9	SKCM	TCGA	VDTST	DEG_SPOP_SBC_1	2835:2839	Mutation rewiring degron network	0.0833
p.E2826K	DO51254	SKCM	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.2222
p.E2826K	DO51254	SKCM	ICGC	VDTST	DEG_SPOP_SBC_1	2835:2839	Mutation rewiring degron network	0.0833
p.D3425N	TCGA-GN-A263	SKCM	TCGA	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.1944
p.D3425N	DO37766	SKCM	ICGC	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.1944
p.E2472G	TCGA-GN-A266	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1667
p.E2472G	DO37432	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1667
p.S2825Y	TCGA-GN-A266	SKCM	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.1944
p.S2825Y	TCGA-GN-A266	SKCM	TCGA	VDTST	DEG_SPOP_SBC_1	2835:2839	Mutation rewiring degron network	0.0556
p.S2825Y	DO37432	SKCM	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.1944
p.S2825Y	DO37432	SKCM	ICGC	VDTST	DEG_SPOP_SBC_1	2835:2839	Mutation rewiring degron network	0.0556
p.T4093N	TCGA-GN-A266	SKCM	TCGA	ASSTT	DEG_SPOP_SBC_1	4079:4083	Mutation rewiring degron network	0.0556
p.T4093N	DO37432	SKCM	ICGC	ASSTT	DEG_SPOP_SBC_1	4079:4083	Mutation rewiring degron network	0.0556
p.S2259L	TCGA-GN-A26C	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.1944
p.S2259L	DO37782	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.1944
p.S3438L	TCGA-GN-A26C	SKCM	TCGA	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.2222
p.S3438L	DO37782	SKCM	ICGC	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.2222
p.P3440S	TCGA-GN-A26C	SKCM	TCGA	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.1667
p.P3440S	TCGA-GN-A26C	SKCM	TCGA	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.0833
p.P3440S	DO37782	SKCM	ICGC	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.1667
p.P3440S	DO37782	SKCM	ICGC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.0833
p.T3140I	TCGA-GN-A8LK	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.3056
p.T3140I	DO51259	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.3056
p.E1765D	TCGA-HT-8106	LGG	TCGA	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation rewiring degron network	0.2778
p.E1765D	TCGA-HT-8106	LGG	TCGA	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.2222
p.E1765D	TCGA-HT-8106	LGG	TCGA	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.1667
p.E1765D	DO22711	LGG	ICGC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation rewiring degron network	0.2778
p.E1765D	DO22711	LGG	ICGC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.2222
p.E1765D	DO22711	LGG	ICGC	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.1667
p.T3468M	TCGA-HU-8249	STAD	TCGA	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation altering degron motif	0.7423
p.T3468M	DO47845	STAD	ICGC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation altering degron motif	0.7423
p.V719M	TCGA-HU-A4G8	STAD	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	708:715	Mutation rewiring degron network	0.2222
p.V719M	TCGA-HU-A4G8	STAD	TCGA	VDTST	DEG_SPOP_SBC_1	713:717	Mutation rewiring degron network	0.2778
p.V719M	DO47819	STAD	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	708:715	Mutation rewiring degron network	0.2222
p.V719M	DO47819	STAD	ICGC	VDTST	DEG_SPOP_SBC_1	713:717	Mutation rewiring degron network	0.2778
p.D3307N	TCGA-HU-A4G8	STAD	TCGA	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation altering degron motif	0.5821
p.D3307N	TCGA-HU-A4G8	STAD	TCGA	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation altering degron motif	0.5821
p.D3307N	DO47819	STAD	ICGC	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation altering degron motif	0.5821
p.D3307N	DO47819	STAD	ICGC	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation altering degron motif	0.5821
p.S2106R	TCGA-HU-A4GH	STAD	TCGA	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.25
p.S2106R	TCGA-HU-A4GH	STAD	TCGA	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.2778
p.S2106R	DO47743	STAD	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.25
p.S2106R	DO47743	STAD	ICGC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.2778
p.V1702A	TCGA-HU-A4GQ	STAD	TCGA	VRTTPVAS	DEG_SCF_FBW7_1	1697:1704	Mutation altering degron motif	0.5825
p.V1702A	DO47767	STAD	ICGC	VRTTPVAS	DEG_SCF_FBW7_1	1697:1704	Mutation altering degron motif	0.5825
p.R4043C	TCGA-IQ-7630	HNSC	TCGA	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation rewiring degron network	0.3056
p.R4043C	TCGA-IQ-7630	HNSC	TCGA	PHTST	DEG_SPOP_SBC_1	4034:4038	Mutation rewiring degron network	0.1944
p.R4043C	DO14654	HNSC	ICGC	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation rewiring degron network	0.3056
p.R4043C	DO14654	HNSC	ICGC	PHTST	DEG_SPOP_SBC_1	4034:4038	Mutation rewiring degron network	0.1944
p.R4043C	SIDM01086	B-Lymphoblastic Leukemia	GDSC	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation rewiring degron network	0.3056
p.R4043C	SIDM01086	B-Lymphoblastic Leukemia	GDSC	PHTST	DEG_SPOP_SBC_1	4034:4038	Mutation rewiring degron network	0.1944
p.R4043C	RS4-11	haematopoietic and lymphoid tissue	COSMIC	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation rewiring degron network	0.3056
p.R4043C	RS4-11	haematopoietic and lymphoid tissue	COSMIC	PHTST	DEG_SPOP_SBC_1	4034:4038	Mutation rewiring degron network	0.1944
p.S2071F	TCGA-J4-A67K	PRAD	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation altering degron motif	0.7982
p.S2071F	DO49828	PRAD	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation altering degron motif	0.7982
p.S1077C	TCGA-JX-A3Q0	CESC	TCGA	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.2778
p.S1077C	DO51607	CESC	ICGC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.2778
p.V937L	TCGA-L5-A4OJ	ESCA	TCGA	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.1389
p.V937L	TCGA-L5-A4OJ	ESCA	TCGA	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.25
p.N598K	TCGA-L5-A8NN	ESCA	TCGA	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation rewiring degron network	0.1389
p.N598K	TCGA-L5-A8NN	ESCA	TCGA	VTTSS	DEG_SPOP_SBC_1	601:605	Mutation rewiring degron network	0.25
p.N598K	TCGA-L5-A8NN	ESCA	TCGA	ASSSS	DEG_SPOP_SBC_1	607:611	Mutation rewiring degron network	0.0833
p.E1334K	TCGA-L5-A8NQ	ESCA	TCGA	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.3056
p.A2115D	TCGA-LN-A5U6	ESCA	TCGA	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.6682
p.S3285T	TCGA-LN-A7HV	ESCA	TCGA	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.2778
p.E1589Q	TCGA-LP-A5U2	CESC	TCGA	LSTTPIDS	DEG_SCF_FBW7_1	1593:1600	Mutation rewiring degron network	0.2222
p.E1589Q	DO51610	CESC	ICGC	LSTTPIDS	DEG_SCF_FBW7_1	1593:1600	Mutation rewiring degron network	0.2222
p.P2457A	TCGA-LT-A5Z6	BLCA	TCGA	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1944
p.P2457A	DO44029	BLCA	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1944
p.T2525M	TCGA-MA-AA3Y	CESC	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation altering degron motif	0.7423
p.T2525M	TCGA-MA-AA3Y	CESC	TCGA	PVSTT	DEG_SPOP_SBC_1	2521:2525	Mutation altering degron motif	0.7423
p.T2525M	TCGA-MP-A4T7	LUAD	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation altering degron motif	0.7423
p.T2525M	TCGA-MP-A4T7	LUAD	TCGA	PVSTT	DEG_SPOP_SBC_1	2521:2525	Mutation altering degron motif	0.7423
p.T2525M	DO219721	CESC	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation altering degron motif	0.7423
p.T2525M	DO219721	CESC	ICGC	PVSTT	DEG_SPOP_SBC_1	2521:2525	Mutation altering degron motif	0.7423
p.T2525M	DO234413	ESAD	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation altering degron motif	0.7423
p.T2525M	DO234413	ESAD	ICGC	PVSTT	DEG_SPOP_SBC_1	2521:2525	Mutation altering degron motif	0.7423
p.T2525M	DO48221	ESCA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation altering degron motif	0.7423
p.T2525M	DO48221	ESCA	ICGC	PVSTT	DEG_SPOP_SBC_1	2521:2525	Mutation altering degron motif	0.7423
p.T2525M	DO45370	LUAD	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation altering degron motif	0.7423
p.T2525M	DO45370	LUAD	ICGC	PVSTT	DEG_SPOP_SBC_1	2521:2525	Mutation altering degron motif	0.7423
p.E3043D	TCGA-MI-A75I	LIHC	TCGA	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.0833
p.E3043D	DO49712	LIHC	ICGC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.0833
p.T2347I	TCGA-MN-A4N4	LUAD	TCGA	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation altering degron motif	0.7078
p.T2347I	DO26250	LUAD	ICGC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation altering degron motif	0.7078
p.S1619N	TCGA-NC-A5HD	LUSC	TCGA	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.1944
p.S1619N	DO219184	LUSC	ICGC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.1944
p.T1524S	TCGA-NC-A5HJ	LUSC	TCGA	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.0556
p.T1524S	DO219189	LUSC	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.0556
p.T3398S	TCGA-NC-A5HJ	LUSC	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.1111
p.T3398S	DO219189	LUSC	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.1111
p.S313I	TCGA-NC-A5HR	LUSC	TCGA	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.25
p.S313I	DO219203	LUSC	ICGC	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.25
p.A2705D	TCGA-NK-A5CR	LUSC	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	2712:2719	Mutation rewiring degron network	0.1389
p.A2705D	DO219207	LUSC	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2712:2719	Mutation rewiring degron network	0.1389
p.R2160K	TCGA-OL-A66P	BRCA	TCGA	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.1389
p.R2160K	DO44182	BRCA	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.1389
p.E1765K	TCGA-PJ-A8JU	KIRP	TCGA	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation rewiring degron network	0.2778
p.E1765K	TCGA-PJ-A8JU	KIRP	TCGA	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.2222
p.E1765K	TCGA-PJ-A8JU	KIRP	TCGA	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.1667
p.E1765K	DO48523	KIRP	ICGC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation rewiring degron network	0.2778
p.E1765K	DO48523	KIRP	ICGC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.2222
p.E1765K	DO48523	KIRP	ICGC	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.1667
p.L581P	TCGA-PL-A8LV	BRCA	TCGA	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation rewiring degron network	0.1667
p.L581P	DO51215	BRCA	ICGC	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation rewiring degron network	0.1667
p.E379K	TCGA-Q1-A73O	CESC	TCGA	VTTST	DEG_SPOP_SBC_1	365:369	Mutation rewiring degron network	0.0556
p.E379K	DO51612	CESC	ICGC	VTTST	DEG_SPOP_SBC_1	365:369	Mutation rewiring degron network	0.0556
p.E3811Q	TCGA-Q1-A73O	CESC	TCGA	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.2778
p.E3811Q	DO51612	CESC	ICGC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.2778
p.S3451A	TCGA-Q9-A6FW	ESCA	TCGA	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation altering degron motif	0.7588
p.G3220R	TCGA-QB-A6FS	SKCM	TCGA	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.3056
p.G3220R	DO48654	SKCM	ICGC	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.3056
p.T4090I	TCGA-QB-AA9O	SKCM	TCGA	ASSTT	DEG_SPOP_SBC_1	4079:4083	Mutation rewiring degron network	0.1389
p.T4090I	DO51267	SKCM	ICGC	ASSTT	DEG_SPOP_SBC_1	4079:4083	Mutation rewiring degron network	0.1389
p.R2160I	TCGA-QF-A5YS	UCEC	TCGA	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.1389
p.R2160I	DO52426	UCEC	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.1389
p.V1172L	TCGA-QG-A5Z1	COAD	TCGA	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.2778
p.V1172L	DO51731	COAD	ICGC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.2778
p.E547K	TCGA-QQ-A5VD	SARC	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation rewiring degron network	0.0833
p.E547K	TCGA-QQ-A5VD	SARC	TCGA	VDTST	DEG_SPOP_SBC_1	536:540	Mutation rewiring degron network	0.1389
p.E547K	TCGA-QQ-A5VD	SARC	TCGA	PVTTS	DEG_SPOP_SBC_1	541:545	Mutation rewiring degron network	0.2778
p.E547K	TCGA-QQ-A5VD	SARC	TCGA	ASSSS	DEG_SPOP_SBC_1	548:552	Mutation rewiring degron network	0.3056
p.E547K	DO222662	MELA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation rewiring degron network	0.0833
p.E547K	DO222662	MELA	ICGC	VDTST	DEG_SPOP_SBC_1	536:540	Mutation rewiring degron network	0.1389
p.E547K	DO222662	MELA	ICGC	PVTTS	DEG_SPOP_SBC_1	541:545	Mutation rewiring degron network	0.2778
p.E547K	DO222662	MELA	ICGC	ASSSS	DEG_SPOP_SBC_1	548:552	Mutation rewiring degron network	0.3056
p.E547K	DO220252	SARC	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation rewiring degron network	0.0833
p.E547K	DO220252	SARC	ICGC	VDTST	DEG_SPOP_SBC_1	536:540	Mutation rewiring degron network	0.1389
p.E547K	DO220252	SARC	ICGC	PVTTS	DEG_SPOP_SBC_1	541:545	Mutation rewiring degron network	0.2778
p.E547K	DO220252	SARC	ICGC	ASSSS	DEG_SPOP_SBC_1	548:552	Mutation rewiring degron network	0.3056
p.S3718Y	TCGA-QS-A5YQ	UCEC	TCGA	VTSTPVTT	DEG_SCF_FBW7_1	3720:3727	Mutation rewiring degron network	0.2778
p.S3718Y	TCGA-QS-A5YQ	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	3724:3728	Mutation rewiring degron network	0.1667
p.S3718Y	DO49073	UCEC	ICGC	VTSTPVTT	DEG_SCF_FBW7_1	3720:3727	Mutation rewiring degron network	0.2778
p.S3718Y	DO49073	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	3724:3728	Mutation rewiring degron network	0.1667
p.S420T	TCGA-RD-A8NB	STAD	TCGA	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation rewiring degron network	0.1667
p.S420T	DO50142	STAD	ICGC	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation rewiring degron network	0.1667
p.L1632V	TCGA-SW-A7EA	STAD	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation rewiring degron network	0.1667
p.L1632V	DO51749	STAD	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation rewiring degron network	0.1667
p.S2868C	TCGA-SX-A7SP	KIRP	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.1111
p.S2868C	DO49790	KIRP	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.1111
p.P3717H	TCGA-UB-A7MB	LIHC	TCGA	VTSTPVTT	DEG_SCF_FBW7_1	3720:3727	Mutation rewiring degron network	0.25
p.P3717H	TCGA-UB-A7MB	LIHC	TCGA	PVTTS	DEG_SPOP_SBC_1	3724:3728	Mutation rewiring degron network	0.1389
p.P3717H	DO52318	LIHC	ICGC	VTSTPVTT	DEG_SCF_FBW7_1	3720:3727	Mutation rewiring degron network	0.25
p.P3717H	DO52318	LIHC	ICGC	PVTTS	DEG_SPOP_SBC_1	3724:3728	Mutation rewiring degron network	0.1389
p.P1367H	TCGA-UF-A71D	HNSC	TCGA	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation altering degron motif	0.7694
p.P1367H	DO52109	HNSC	ICGC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation altering degron motif	0.7694
p.S532P	TCGA-UF-A7J9	HNSC	TCGA	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation altering degron motif	0.5641
p.S532P	DO52111	HNSC	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation altering degron motif	0.5641
p.T853S	TCGA-UY-A78K	BLCA	TCGA	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.0556
p.T853S	DO219031	BLCA	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.0556
p.V1368E	TCGA-UY-A78K	BLCA	TCGA	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation altering degron motif	0.6582
p.V1368E	DO219031	BLCA	ICGC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation altering degron motif	0.6582
p.S3438T	TCGA-UY-A78K	BLCA	TCGA	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.2222
p.S3438T	DO219031	BLCA	ICGC	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.2222
p.S958F	TCGA-UY-A8OD	BLCA	TCGA	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation altering degron motif	0.9093
p.S958F	DO219039	BLCA	ICGC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation altering degron motif	0.9093
p.S2254F	TCGA-UY-A8OD	BLCA	TCGA	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation altering degron motif	0.7982
p.S2254F	DO219039	BLCA	ICGC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation altering degron motif	0.7982
p.P3057L	TCGA-UY-A9PB	BLCA	TCGA	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.0833
p.P3057L	TCGA-UY-A9PB	BLCA	TCGA	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.3056
p.P3057L	DO219041	BLCA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.0833
p.P3057L	DO219041	BLCA	ICGC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.3056
p.T1266S	TCGA-V1-A8WW	PRAD	TCGA	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1111
p.T1266S	TCGA-V1-A8WW	PRAD	TCGA	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.25
p.T1266S	DO219365	PRAD	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1111
p.T1266S	DO219365	PRAD	ICGC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.25
p.R4485M	TCGA-VQ-A8P2	STAD	TCGA	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation rewiring degron network	0.25
p.R4485M	DO51761	STAD	ICGC	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation rewiring degron network	0.25
p.T3937A	TCGA-VQ-A8PX	STAD	TCGA	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.2222
p.T3937A	TCGA-VQ-A8PX	STAD	TCGA	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation rewiring degron network	0.1111
p.T3937A	DO51778	STAD	ICGC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.2222
p.T3937A	DO51778	STAD	ICGC	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation rewiring degron network	0.1111
p.S195R	TCGA-VQ-A94R	STAD	TCGA	MSTPLTT	DEG_SCF_FBW7_1	184:190	Mutation rewiring degron network	0.1944
p.S195R	TCGA-VQ-A94R	STAD	TCGA	PLTTS	DEG_SPOP_SBC_1	187:191	Mutation rewiring degron network	0.2222
p.S195R	TCGA-VQ-A94R	STAD	TCGA	PESTT	DEG_SPOP_SBC_1	201:205	Mutation rewiring degron network	0.1667
p.S195R	DO222372	STAD	ICGC	MSTPLTT	DEG_SCF_FBW7_1	184:190	Mutation rewiring degron network	0.1944
p.S195R	DO222372	STAD	ICGC	PLTTS	DEG_SPOP_SBC_1	187:191	Mutation rewiring degron network	0.2222
p.S195R	DO222372	STAD	ICGC	PESTT	DEG_SPOP_SBC_1	201:205	Mutation rewiring degron network	0.1667
p.T2852K	TCGA-VQ-AA6A	STAD	TCGA	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation rewiring degron network	0.1111
p.T2852K	DO222387	STAD	ICGC	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation rewiring degron network	0.1111
p.A2257D	TCGA-VS-A9UA	CESC	TCGA	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.0556
p.A2257D	TCGA-VS-A9UA	CESC	TCGA	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.25
p.A2257D	DO219730	CESC	ICGC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.0556
p.A2257D	DO219730	CESC	ICGC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.25
p.P2126A	TCGA-VS-A9UH	CESC	TCGA	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.0556
p.P2126A	DO51642	CESC	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.0556
p.G1158E	TCGA-W3-A825	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1111
p.G1158E	DO51272	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1111
p.P1926L	TCGA-W3-A825	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.1667
p.P1926L	DO51272	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.1667
p.P4044L	TCGA-W3-AA1R	SKCM	TCGA	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation altering degron motif	0.6471
p.P4044L	DO51275	SKCM	ICGC	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation altering degron motif	0.6471
p.P965L	TCGA-W3-AA1V	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.1389
p.P965L	DO51276	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.1389
p.P1496S	TCGA-W3-AA1V	SKCM	TCGA	AVSSS	DEG_SPOP_SBC_1	1491:1495	Mutation rewiring degron network	0.3056
p.P1496S	DO51276	SKCM	ICGC	AVSSS	DEG_SPOP_SBC_1	1491:1495	Mutation rewiring degron network	0.3056
p.G3103E	TCGA-W3-AA1W	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	3111:3115	Mutation rewiring degron network	0.1111
p.G3103E	DO229446	SKCA	ICGC	PVSTT	DEG_SPOP_SBC_1	3111:3115	Mutation rewiring degron network	0.1111
p.G3103E	DO51277	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	3111:3115	Mutation rewiring degron network	0.1111
p.T3421I	TCGA-WN-A9G9	KIRP	TCGA	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.1111
p.T3421I	TCGA-WN-A9G9	KIRP	TCGA	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.0833
p.T3421I	DO51569	KIRP	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.1111
p.T3421I	DO51569	KIRP	ICGC	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.0833
p.E4087D	TCGA-X6-A7WB	SARC	TCGA	ASSTT	DEG_SPOP_SBC_1	4079:4083	Mutation rewiring degron network	0.2222
p.E4087D	DO220314	SARC	ICGC	ASSTT	DEG_SPOP_SBC_1	4079:4083	Mutation rewiring degron network	0.2222
p.T2247I	TCGA-XF-A8HD	BLCA	TCGA	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation altering degron motif	0.7078
p.T2247I	DO49795	BLCA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation altering degron motif	0.7078
p.T3539K	TCGA-XF-A8HF	BLCA	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation rewiring degron network	0.1111
p.T3539K	TCGA-XF-A8HF	BLCA	TCGA	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.0833
p.T3539K	DO49800	BLCA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation rewiring degron network	0.1111
p.T3539K	DO49800	BLCA	ICGC	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.0833
p.E586Q	TCGA-XF-A9T8	BLCA	TCGA	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation rewiring degron network	0.3056
p.E586Q	DO51927	BLCA	ICGC	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation rewiring degron network	0.3056
p.T3638S	TCGA-XF-AAMR	BLCA	TCGA	PVSTT	DEG_SPOP_SBC_1	3641:3645	Mutation rewiring degron network	0.25
p.T3638S	DO51935	BLCA	ICGC	PVSTT	DEG_SPOP_SBC_1	3641:3645	Mutation rewiring degron network	0.25
p.R3705C	TCGA-XK-AAIW	PRAD	TCGA	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.3056
p.R3705C	DO223416	CLLE	ICGC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.3056
p.R3705C	DO51407	PRAD	ICGC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.3056
p.R3705C	SIDM01016	T-Lymphoblastic Leukemia	GDSC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.3056
p.R3705C	SIDM01263	T-Lymphoblastic Leukemia	GDSC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.3056
p.R3705C	SIDM01434	Hepatocellular Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.3056
p.R3705C	ACH-000316	Liver Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.3056
p.R3705C	ACH-000995	Leukemia	CCLE	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.3056
p.R3705C	Jurkat	haematopoietic and lymphoid tissue	COSMIC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.3056
p.S1645T	TCGA-XQ-A8TA	PRAD	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation altering degron motif	0.6005
p.S1645T	DO223662	PRAD	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation altering degron motif	0.6005
p.G2336E	TCGA-YD-A9TA	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1111
p.G2336E	DO219503	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1111
p.P3047L	TCGA-YD-A9TA	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.1944
p.P3047L	DO219503	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.1944
p.S1718N	TCGA-YG-AA3N	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.2778
p.S1718N	DO51298	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.2778
p.S1552N	TCGA-YZ-A982	UVM	TCGA	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0833
p.A162V	TCGA-Z2-A8RT	SKCM	TCGA	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation rewiring degron network	0.1389
p.A162V	DO51301	SKCM	ICGC	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation rewiring degron network	0.1389
p.L178F	TCGA-Z2-A8RT	SKCM	TCGA	MSTPLTT	DEG_SCF_FBW7_1	184:190	Mutation rewiring degron network	0.1667
p.L178F	TCGA-Z2-A8RT	SKCM	TCGA	PLTTS	DEG_SPOP_SBC_1	187:191	Mutation rewiring degron network	0.0833
p.L178F	DO51301	SKCM	ICGC	MSTPLTT	DEG_SCF_FBW7_1	184:190	Mutation rewiring degron network	0.1667
p.L178F	DO51301	SKCM	ICGC	PLTTS	DEG_SPOP_SBC_1	187:191	Mutation rewiring degron network	0.0833
p.S3532C	TCGA-Z6-AAPN	ESCA	TCGA	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation rewiring degron network	0.3056
p.S3532C	TCGA-Z6-AAPN	ESCA	TCGA	PVSTT	DEG_SPOP_SBC_1	3523:3527	Mutation rewiring degron network	0.1944
p.T2784I	DO48362	BLCA	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation altering degron motif	0.7078
p.E3082K	DO48372	BLCA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.0833
p.S2346N	DO48371	BLCA	ICGC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation altering degron motif	0.7069
p.E2551Q	DO48371	BLCA	ICGC	VVTST	DEG_SPOP_SBC_1	2546:2550	Mutation rewiring degron network	0.3056
p.T339M	DO882	BOCA	ICGC	LTSTPAST	DEG_SCF_FBW7_1	336:343	Mutation altering degron motif	0.7423
p.T339M	DO882	BOCA	ICGC	PLTST	DEG_SPOP_SBC_1	335:339	Mutation altering degron motif	0.7423
p.T339M	DO229016	COCA	ICGC	LTSTPAST	DEG_SCF_FBW7_1	336:343	Mutation altering degron motif	0.7423
p.T339M	DO229016	COCA	ICGC	PLTST	DEG_SPOP_SBC_1	335:339	Mutation altering degron motif	0.7423
p.T339M	DO230659	LAML	ICGC	LTSTPAST	DEG_SCF_FBW7_1	336:343	Mutation altering degron motif	0.7423
p.T339M	DO230659	LAML	ICGC	PLTST	DEG_SPOP_SBC_1	335:339	Mutation altering degron motif	0.7423
p.T339M	DO231140	LAML	ICGC	LTSTPAST	DEG_SCF_FBW7_1	336:343	Mutation altering degron motif	0.7423
p.T339M	DO231140	LAML	ICGC	PLTST	DEG_SPOP_SBC_1	335:339	Mutation altering degron motif	0.7423
p.T339M	DO228941	LICA	ICGC	LTSTPAST	DEG_SCF_FBW7_1	336:343	Mutation altering degron motif	0.7423
p.T339M	DO228941	LICA	ICGC	PLTST	DEG_SPOP_SBC_1	335:339	Mutation altering degron motif	0.7423
p.T339M	DO228947	LICA	ICGC	LTSTPAST	DEG_SCF_FBW7_1	336:343	Mutation altering degron motif	0.7423
p.T339M	DO228947	LICA	ICGC	PLTST	DEG_SPOP_SBC_1	335:339	Mutation altering degron motif	0.7423
p.P2875L	DO52611	BOCA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.3056
p.T1713I	DO233964	BPLL	ICGC	VRTTPVAS	DEG_SCF_FBW7_1	1697:1704	Mutation rewiring degron network	0.0833
p.T1713I	DO233964	BPLL	ICGC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.1389
p.P712S	DO217844	BRCA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	708:715	Mutation altering degron motif	0.6752
p.P712S	DO220893	MELA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	708:715	Mutation altering degron motif	0.6752
p.T1748I	DO225007	BRCA	ICGC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation rewiring degron network	0.1111
p.T1748I	DO225007	BRCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.1389
p.S4039F	DO225046	BRCA	ICGC	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation rewiring degron network	0.1944
p.S4039F	DO225046	BRCA	ICGC	PHTST	DEG_SPOP_SBC_1	4034:4038	Mutation rewiring degron network	0.3056
p.E3435K	DO225391	BRCA	ICGC	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.3056
p.S191F	DO224920	BRCA	ICGC	PLTTS	DEG_SPOP_SBC_1	187:191	Mutation altering degron motif	0.7982
p.S3447T	DO228483	BRCA	ICGC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.2778
p.S3447T	SIDM00377	Other Sarcomas	GDSC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.2778
p.S3447T	SIDM00568	Gastric Carcinoma	GDSC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.2778
p.S3447T	SIDM00556	Neuroblastoma	GDSC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.2778
p.S3447T	SIDM00817	Kidney Carcinoma	GDSC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.2778
p.S3447T	SIDM01180	Hepatocellular Carcinoma	GDSC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.2778
p.S3447T	SKN	soft tissue	COSMIC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.2778
p.S3447T	OCUM-1	stomach	COSMIC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.2778
p.S3447T	SNU-387	liver	COSMIC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.2778
p.S3447T	KP-N-YN	autonomic ganglia	COSMIC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.2778
p.A312T	DO228483	BRCA	ICGC	LSTTPAAT	DEG_SCF_FBW7_1	295:302	Mutation rewiring degron network	0.0556
p.A312T	DO228483	BRCA	ICGC	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.2778
p.T3540S	DO1110	BRCA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation rewiring degron network	0.0833
p.T3540S	DO1110	BRCA	ICGC	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.1111
p.Q2374E	DO1156	BRCA	ICGC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.0833
p.S2078F	DO223000	BTCA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation rewiring degron network	0.1389
p.S2078F	DO222843	MELA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation rewiring degron network	0.1389
p.V1839G	DO222388	BTCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1944
p.P1260R	DO222414	BTCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.2778
p.P1260R	DO222414	BTCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.0833
p.T3056M	DO222530	BTCA	ICGC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation altering degron motif	0.7423
p.T3056M	DO229016	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation altering degron motif	0.7423
p.T3056M	DO230659	LAML	ICGC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation altering degron motif	0.7423
p.T3056M	DO231140	LAML	ICGC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation altering degron motif	0.7423
p.T3056M	DO228941	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation altering degron motif	0.7423
p.T3056M	DO228947	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation altering degron motif	0.7423
p.T3056M	DO229047	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation altering degron motif	0.7423
p.T3526N	DO222907	BTCA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation altering degron motif	0.5944
p.T3526N	DO222907	BTCA	ICGC	PVSTT	DEG_SPOP_SBC_1	3523:3527	Mutation altering degron motif	0.7055
p.L2109V	DO229376	BTCA	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.5654
p.L2109V	DO229376	BTCA	ICGC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation altering degron motif	0.5654
p.P2821S	DO8264	COAD	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0833
p.A1353T	DO230311	COCA	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.0556
p.S451N	DO230326	COCA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation rewiring degron network	0.1111
p.S451N	DO230326	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	458:462	Mutation rewiring degron network	0.1389
p.E940V	DO227976	COCA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.2222
p.E940V	DO227976	COCA	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1667
p.E940V	DO227976	COCA	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.0833
p.S153N	DO227984	COCA	ICGC	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation altering degron motif	0.5958
p.T1614A	DO227987	COCA	ICGC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation altering degron motif	0.7139
p.S2785A	DO227999	COCA	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation altering degron motif	0.7588
p.S2785A	DO229016	COCA	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation altering degron motif	0.7588
p.S2785A	DO230659	LAML	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation altering degron motif	0.7588
p.S2785A	DO231140	LAML	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation altering degron motif	0.7588
p.S2785A	DO228941	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation altering degron motif	0.7588
p.S2785A	DO228947	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation altering degron motif	0.7588
p.S2785A	DO229047	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation altering degron motif	0.7588
p.T1246N	DO224661	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1111
p.T1246N	DO224731	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1111
p.T1246N	DO222553	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1111
p.T1246N	DO229013	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1111
p.T1246N	DO229016	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1111
p.T1246S	DO224661	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1111
p.T1246S	DO224731	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1111
p.T1246S	DO222553	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1111
p.T1246S	DO222737	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1111
p.T1246S	DO229013	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1111
p.T1246S	DO229016	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1111
p.A1858P	DO224685	COCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.0556
p.A1858P	DO224731	COCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.0556
p.A1858P	DO229016	COCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.0556
p.A2459T	DO224775	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.25
p.A2459T	DO228611	GACA	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.25
p.V2771L	DO224786	COCA	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation rewiring degron network	0.0556
p.T667S	DO224701	COCA	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation altering degron motif	0.6005
p.T667S	DO228960	LICA	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation altering degron motif	0.6005
p.T667S	DO229030	LICA	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation altering degron motif	0.6005
p.T667S	DO229052	LICA	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation altering degron motif	0.6005
p.T1291S	DO224708	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.25
p.T1291S	DO224812	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.25
p.T1291S	DO222553	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.25
p.T1291S	DO229013	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.25
p.T1291S	DO229016	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.25
p.T1291S	DO51009	LAML	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.25
p.T1291S	DO52361	LUSC	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.25
p.T1291S	DO52359	LUSC	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.25
p.G2474S	DO224716	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1111
p.G2474S	DO228915	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1111
p.G2474S	DO229053	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1111
p.S1549P	DO224726	COCA	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.1111
p.S1549P	DO224726	COCA	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.1667
p.S1549P	DO224731	COCA	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.1111
p.S1549P	DO224731	COCA	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.1667
p.T1541P	DO224731	COCA	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.7031
p.T1541P	DO224731	COCA	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.7031
p.T1541P	DO224754	COCA	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.7031
p.T1541P	DO224754	COCA	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.7031
p.T1541P	DO222718	COCA	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.7031
p.T1541P	DO222718	COCA	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.7031
p.T1541P	DO228390	LICA	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.7031
p.T1541P	DO228390	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.7031
p.T1541P	DO228531	LICA	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.7031
p.T1541P	DO228531	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.7031
p.T1541P	DO52361	LUSC	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.7031
p.T1541P	DO52361	LUSC	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.7031
p.T1541P	DO52357	LUSC	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.7031
p.T1541P	DO52357	LUSC	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.7031
p.V2172L	DO224731	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.3056
p.V2172L	DO228926	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.3056
p.V2172L	DO228941	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.3056
p.V2172L	DO228947	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.3056
p.V2172L	DO228974	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.3056
p.I1857M	DO224731	COCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.0833
p.I1857M	DO222560	COCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.0833
p.I1857M	DO229016	COCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.0833
p.I1943T	DO224731	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.1389
p.A1499T	DO224731	COCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1491:1495	Mutation rewiring degron network	0.2222
p.I1931M	DO224731	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.3056
p.I1931M	DO48940	PBCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.3056
p.P1496L	DO224731	COCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1491:1495	Mutation rewiring degron network	0.3056
p.T1945S	DO224731	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation blocking phosphorylation signal	0.5278
p.T1886S	DO224731	COCA	ICGC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1667
p.T1886S	DO224754	COCA	ICGC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1667
p.T1886S	TMK-1	stomach	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1667
p.T1262S	DO224735	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.2222
p.T1262S	DO224735	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.1389
p.T1262S	DO222553	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.2222
p.T1262S	DO222553	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.1389
p.T1262S	DO222737	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.2222
p.T1262S	DO222737	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.1389
p.T1262S	DO229013	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.2222
p.T1262S	DO229013	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.1389
p.T1262S	DO229016	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.2222
p.T1262S	DO229016	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.1389
p.S3299N	DO224754	COCA	ICGC	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.2778
p.S3299N	DO224754	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.1111
p.S3299N	DO224754	COCA	ICGC	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation rewiring degron network	0.1389
p.S3299N	DO229013	COCA	ICGC	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.2778
p.S3299N	DO229013	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.1111
p.S3299N	DO229013	COCA	ICGC	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation rewiring degron network	0.1389
p.S3299N	DO229016	COCA	ICGC	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.2778
p.S3299N	DO229016	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.1111
p.S3299N	DO229016	COCA	ICGC	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation rewiring degron network	0.1389
p.S3299N	DO52365	LUSC	ICGC	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.2778
p.S3299N	DO52365	LUSC	ICGC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.1111
p.S3299N	DO52365	LUSC	ICGC	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation rewiring degron network	0.1389
p.T3300S	DO224754	COCA	ICGC	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.3056
p.T3300S	DO224754	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.0833
p.T3300S	DO224754	COCA	ICGC	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation rewiring degron network	0.1667
p.A1852T	DO224754	COCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.2222
p.A1852T	DO229016	COCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.2222
p.A1852T	DO218898	SKCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.2222
p.V3227I	DO222480	COCA	ICGC	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.3056
p.V3227I	DO222588	COCA	ICGC	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.3056
p.V3227I	DO229004	LICA	ICGC	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.3056
p.S611P	DO222507	COCA	ICGC	ASSSS	DEG_SPOP_SBC_1	607:611	Mutation altering degron motif	0.6752
p.G920R	DO222519	COCA	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.0556
p.G920R	DO229013	COCA	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.0556
p.G920R	DO229016	COCA	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.0556
p.T1288K	DO222553	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation altering degron motif	0.7306
p.T1288K	DO222835	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation altering degron motif	0.7306
p.T1288K	DO229013	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation altering degron motif	0.7306
p.T1288K	DO229016	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation altering degron motif	0.7306
p.T1288K	DO51020	LAML	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation altering degron motif	0.7306
p.T1288K	DO51011	LAML	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation altering degron motif	0.7306
p.T1288K	DO51009	LAML	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation altering degron motif	0.7306
p.T1288K	DO52359	LUSC	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation altering degron motif	0.7306
p.T1288K	DO218859	SKCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation altering degron motif	0.7306
p.G863E	DO222553	COCA	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation altering degron motif	0.6087
p.G863E	DO229016	COCA	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation altering degron motif	0.6087
p.G863E	DO52365	LUSC	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation altering degron motif	0.6087
p.G1688E	DO222553	COCA	ICGC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.6087
p.G1688E	DO52365	LUSC	ICGC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.6087
p.G1688E	DO218859	SKCA	ICGC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.6087
p.S1277I	DO222553	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.2222
p.S1277I	DO222553	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.1389
p.S1277I	DO229013	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.2222
p.S1277I	DO229013	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.1389
p.S1277I	DO229016	COCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.2222
p.S1277I	DO229016	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.1389
p.S1277I	DO52365	LUSC	ICGC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.2222
p.S1277I	DO52365	LUSC	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.1389
p.P1249A	DO222553	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1944
p.P1249A	DO222874	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1944
p.P1249A	DO229013	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1944
p.P1249A	DO229016	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1944
p.P1249A	DO228941	LICA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1944
p.P1249A	DO228947	LICA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.1944
p.S861T	DO222553	COCA	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.2778
p.S861T	DO229013	COCA	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.2778
p.S861T	DO229016	COCA	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.2778
p.S861T	DO50851	LIRI	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.2778
p.S861T	DO230556	LUSC	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.2778
p.S861T	DO52357	LUSC	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.2778
p.T1696P	DO222553	COCA	ICGC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.5919
p.T959A	DO222755	COCA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.1111
p.T959A	DO222755	COCA	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1667
p.T959A	DO222755	COCA	ICGC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.3056
p.T959A	DO222869	COCA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.1111
p.T959A	DO222869	COCA	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1667
p.T959A	DO222869	COCA	ICGC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.3056
p.T959A	DO229013	COCA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.1111
p.T959A	DO229013	COCA	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1667
p.T959A	DO229013	COCA	ICGC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.3056
p.T959A	DO229016	COCA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.1111
p.T959A	DO229016	COCA	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1667
p.T959A	DO229016	COCA	ICGC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.3056
p.T959A	DO52365	LUSC	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.1111
p.T959A	DO52365	LUSC	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1667
p.T959A	DO52365	LUSC	ICGC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.3056
p.T959A	DO52357	LUSC	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.1111
p.T959A	DO52357	LUSC	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1667
p.T959A	DO52357	LUSC	ICGC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.3056
p.A465S	DO222755	COCA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation altering degron motif	0.6477
p.A465S	DO229015	LICA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation altering degron motif	0.6477
p.V1540D	DO222718	COCA	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.6674
p.V1540D	DO222718	COCA	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.6674
p.V1540D	DO228390	LICA	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.6674
p.V1540D	DO228390	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.6674
p.V1540D	DO228531	LICA	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.6674
p.V1540D	DO228531	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.6674
p.V1540D	DO228950	LICA	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.6674
p.V1540D	DO228950	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.6674
p.V1540D	DO228967	LICA	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.6674
p.V1540D	DO228967	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.6674
p.V1540D	DO229030	LICA	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.6674
p.V1540D	DO229030	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.6674
p.V1540D	DO229057	LICA	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.6674
p.V1540D	DO229057	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.6674
p.V1540D	DO52361	LUSC	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.6674
p.V1540D	DO52361	LUSC	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.6674
p.V1540D	DO52357	LUSC	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation altering degron motif	0.6674
p.V1540D	DO52357	LUSC	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.6674
p.P1161Q	DO222884	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1944
p.T422N	DO222884	COCA	ICGC	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation rewiring degron network	0.1111
p.P866T	DO52481	COCA	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation altering degron motif	0.5919
p.P2880L	DO52481	COCA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.7582
p.P2880L	DO229346	LAML	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.7582
p.P2880L	DO229052	LICA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.7582
p.P2880L	SIDM00234	Other Solid Cancers	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.7582
p.P2880L	SIDM00377	Other Sarcomas	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.7582
p.P2880L	SIDM00655	Other Solid Cancers	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.7582
p.P2880L	SIDM01033	Bladder Carcinoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.7582
p.P2880L	SKN	soft tissue	COSMIC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.7582
p.P2880L	KU-19-19	urinary tract	COSMIC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.7582
p.P2880L	TC-YIK	cervix	COSMIC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.7582
p.P2880L	NCCIT	testis	COSMIC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.7582
p.T3549S	DO222800	COCA	ICGC	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation altering degron motif	0.6005
p.A941V	DO222849	COCA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.25
p.A941V	DO222849	COCA	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1389
p.A941V	DO222849	COCA	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1111
p.A941V	DO229013	COCA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.25
p.A941V	DO229013	COCA	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1389
p.A941V	DO229013	COCA	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1111
p.A941V	DO229016	COCA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.25
p.A941V	DO229016	COCA	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1389
p.A941V	DO229016	COCA	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1111
p.I1130T	DO229010	COCA	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.3056
p.I1130T	DO229013	COCA	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.3056
p.I1130T	DO229016	COCA	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.3056
p.I1130T	DO229003	COCA	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.3056
p.I1130T	DO229005	COCA	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.3056
p.R2159G	DO229013	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.1111
p.R2159G	DO229016	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.1111
p.R2159G	DO228941	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.1111
p.R2159G	DO228947	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.1111
p.C1375R	DO229013	COCA	ICGC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.2222
p.C1375R	DO229016	COCA	ICGC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.2222
p.C1375R	DO228941	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.2222
p.C1375R	DO228947	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.2222
p.S1083P	DO229013	COCA	ICGC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation altering degron motif	0.6752
p.S1083P	DO229016	COCA	ICGC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation altering degron motif	0.6752
p.G272E	DO229013	COCA	ICGC	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation rewiring degron network	0.1667
p.G272E	DO229016	COCA	ICGC	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation rewiring degron network	0.1667
p.G272E	DO229052	LICA	ICGC	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation rewiring degron network	0.1667
p.G272E	DO230550	LUSC	ICGC	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation rewiring degron network	0.1667
p.G272E	DO52365	LUSC	ICGC	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation rewiring degron network	0.1667
p.S3285G	DO229013	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.2778
p.S3285G	DO229016	COCA	ICGC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.2778
p.S3285G	DO52365	LUSC	ICGC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.2778
p.T1686S	DO229013	COCA	ICGC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation rewiring degron network	0.2778
p.T1686S	DO229016	COCA	ICGC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation rewiring degron network	0.2778
p.T1093A	DO229013	COCA	ICGC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.0556
p.T1093A	DO229016	COCA	ICGC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.0556
p.A2081D	DO229013	COCA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation rewiring degron network	0.0556
p.A2081D	DO229016	COCA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation rewiring degron network	0.0556
p.A2081D	DO234205	ESAD	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation rewiring degron network	0.0556
p.A2081D	DO52365	LUSC	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation rewiring degron network	0.0556
p.L1348P	DO229013	COCA	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.1944
p.L1348P	DO229016	COCA	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.1944
p.L1348P	DO228941	LICA	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.1944
p.L1348P	DO228947	LICA	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.1944
p.R942S	DO229013	COCA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.2778
p.R942S	DO229013	COCA	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1111
p.R942S	DO229013	COCA	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1389
p.R942S	DO229016	COCA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.2778
p.R942S	DO229016	COCA	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1111
p.R942S	DO229016	COCA	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1389
p.R942S	DO52365	LUSC	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.2778
p.R942S	DO52365	LUSC	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1111
p.R942S	DO52365	LUSC	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1389
p.T879S	DO229013	COCA	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.1111
p.T879S	DO229016	COCA	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.1111
p.T879S	DO228390	LICA	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.1111
p.T879S	DO228531	LICA	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.1111
p.T879S	DO228012	SKCA	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.1111
p.E940G	DO229013	COCA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.2222
p.E940G	DO229013	COCA	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1667
p.E940G	DO229013	COCA	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.0833
p.E940G	DO229016	COCA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.2222
p.E940G	DO229016	COCA	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1667
p.E940G	DO229016	COCA	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.0833
p.T1256I	DO229016	COCA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation altering degron motif	0.7078
p.T1256I	DO230659	LAML	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation altering degron motif	0.7078
p.T1256I	DO231140	LAML	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation altering degron motif	0.7078
p.T1256I	DO228941	LICA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation altering degron motif	0.7078
p.T1256I	DO228947	LICA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation altering degron motif	0.7078
p.T1256I	DO229047	LICA	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation altering degron motif	0.7078
p.E1853D	DO229016	COCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1944
p.E1853D	DO46877	RECA	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1944
p.T1855S	DO229016	COCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	RERF-LC-Sq1	lung	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	ECC10	stomach	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	8505C	thyroid	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	PL-21	haematopoietic and lymphoid tissue	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	KMRC-1	kidney	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	BFTC-909	kidney	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	MKN28	stomach	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	LK-2	lung	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	KMS-12-BM	haematopoietic and lymphoid tissue	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	SNU-61	large intestine	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	TE-12	oesophagus	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	SBC-1	lung	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	NY	bone	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	RH-18	soft tissue	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	P12-ICHIKAWA	haematopoietic and lymphoid tissue	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	KP-4	pancreas	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	RCC-ER	kidney	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	JHH-6	liver	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	TMK-1	stomach	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	NCI-SNU-16	stomach	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	KYSE-140	oesophagus	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	MOLM-16	haematopoietic and lymphoid tissue	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	KY821	haematopoietic and lymphoid tissue	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	HGC-27	stomach	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	AM-38	central nervous system	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	YH-13	central nervous system	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	IM-95	stomach	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	SNU-423	liver	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	CML-T1	haematopoietic and lymphoid tissue	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	HCC1419	breast	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	SNU-283	large intestine	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	SNU-C5	large intestine	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855S	KINGS-1	central nervous system	COSMIC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.A1844E	DO229016	COCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation altering degron motif	0.7701
p.I2780T	DO229016	COCA	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation rewiring degron network	0.3056
p.I2780T	DO229053	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation rewiring degron network	0.3056
p.I2780T	DO229057	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation rewiring degron network	0.3056
p.S1846T	DO229016	COCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation altering degron motif	0.6005
p.P1851T	DO229016	COCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.25
p.P1851T	DO45151	LIRI	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.25
p.T838I	DO229016	COCA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.1944
p.T838I	DO229348	LAML	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.1944
p.T838I	DO228941	LICA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.1944
p.T838I	DO228943	LICA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.1944
p.T838I	DO228947	LICA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.1944
p.T838I	DO228950	LICA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.1944
p.T838I	DO224626	LUSC	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.1944
p.T838I	DO222494	MELA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.1944
p.G144D	DO229016	COCA	ICGC	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation rewiring degron network	0.2222
p.G144D	DO230659	LAML	ICGC	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation rewiring degron network	0.2222
p.G144D	DO231140	LAML	ICGC	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation rewiring degron network	0.2222
p.G144D	DO228941	LICA	ICGC	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation rewiring degron network	0.2222
p.G144D	DO228947	LICA	ICGC	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation rewiring degron network	0.2222
p.G144D	DO229047	LICA	ICGC	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation rewiring degron network	0.2222
p.V1845G	DO229016	COCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation altering degron motif	0.6421
p.T589P	DO229016	COCA	ICGC	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation altering degron motif	0.7031
p.P1849L	DO229016	COCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.3056
p.T2786A	DO229016	COCA	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation rewiring degron network	0.3056
p.G3932R	DO229003	COCA	ICGC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	DO229005	COCA	ICGC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	DO229480	LAML	ICGC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	DO231075	LUSC	ICGC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00450	Acute Myeloid Leukemia	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00608	Plasma Cell Myeloma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00437	Acute Myeloid Leukemia	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01034	B-Lymphoblastic Leukemia	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00586	Hepatocellular Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00435	Acute Myeloid Leukemia	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00545	Melanoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00234	Other Solid Cancers	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00232	Kidney Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00611	Kidney Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00075	Non-Cancerous	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01197	Colorectal Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00781	Colorectal Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00367	Small Cell Lung Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00291	Melanoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00370	T-Lymphoblastic Leukemia	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00315	Glioblastoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00308	Chronic Myelogenous Leukemia	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00362	Burkitt's Lymphoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00231	Kidney Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01259	B-Lymphoblastic Leukemia	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00193	Colorectal Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00573	Glioblastoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00592	Oral Cavity Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00598	Squamous Cell Lung Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00354	Squamous Cell Lung Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00355	Non-Small Cell Lung Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00350	Head and Neck Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01181	Hepatocellular Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00364	B-Lymphoblastic Leukemia	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00238	Ovarian Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00568	Gastric Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00282	Colorectal Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00195	Ewing's Sarcoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00596	Endometrial Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00384	B-Cell Non-Hodgkin's Lymphoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01045	Endometrial Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00375	Head and Neck Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00489	Oral Cavity Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00292	Small Cell Lung Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00294	Small Cell Lung Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00250	Esophageal Squamous Cell Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00252	Biliary Tract Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00237	Non-Small Cell Lung Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00276	Biliary Tract Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00298	Squamous Cell Lung Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00502	B-Lymphoblastic Leukemia	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00567	Other Solid Cancers	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00247	Gastric Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01653	Non-Cancerous	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00357	Small Cell Lung Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00347	Esophageal Squamous Cell Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01210	Glioblastoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00207	Glioblastoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00549	B-Lymphoblastic Leukemia	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00561	Other Blood Cancers	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00249	Esophageal Squamous Cell Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01217	Other Blood Cancers	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00271	Gastric Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00368	Small Cell Lung Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00566	Oral Cavity Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00217	Colorectal Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00380	Acute Myeloid Leukemia	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00289	B-Lymphoblastic Leukemia	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00363	Acute Myeloid Leukemia	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01025	Esophageal Squamous Cell Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00448	B-Cell Non-Hodgkin's Lymphoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00316	Glioblastoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00274	Gastric Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00603	Head and Neck Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00273	Glioblastoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00359	Colorectal Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00531	Pancreatic Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01439	Hepatocellular Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00192	Colorectal Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01728	Endometrial Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01612	Endometrial Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01617	Endometrial Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01570	Ovarian Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01577	Plasma Cell Myeloma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00169	Head and Neck Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00158	Glioblastoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01472	Hepatocellular Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01573	Plasma Cell Myeloma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00780	Colorectal Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01446	Glioblastoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01447	Glioblastoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01691	Chronic Myelogenous Leukemia	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01450	Gastric Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01448	Head and Neck Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01454	Kidney Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01321	Pancreatic Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01378	Ovarian Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01782	Oral Cavity Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01685	B-Lymphoblastic Leukemia	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01694	B-Lymphoblastic Leukemia	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01764	Non-Small Cell Lung Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00016	Neuroblastoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM01442	Glioma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00162	Biliary Tract Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00015	Esophageal Squamous Cell Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	SIDM00159	Biliary Tract Carcinoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932R	Mewo	skin	COSMIC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.A2775P	DO227427	EOPC	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation rewiring degron network	0.1667
p.A2775P	DO228920	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation rewiring degron network	0.1667
p.A2775P	DO228960	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation rewiring degron network	0.1667
p.I2520M	DO227427	EOPC	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation rewiring degron network	0.2778
p.I2520M	DO227427	EOPC	ICGC	PVSTT	DEG_SPOP_SBC_1	2521:2525	Mutation rewiring degron network	0.3056
p.S1757G	DO50452	ESAD	ICGC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation altering degron motif	0.5882
p.S1757G	DO50452	ESAD	ICGC	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation altering degron motif	0.6993
p.S466R	DO50407	ESAD	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation altering degron motif	0.7427
p.R3705H	DO50362	ESAD	ICGC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.3056
p.T2538P	DO234212	ESAD	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation rewiring degron network	0.0833
p.T2538P	DO234212	ESAD	ICGC	VVTST	DEG_SPOP_SBC_1	2546:2550	Mutation rewiring degron network	0.1111
p.R580G	DO234230	ESAD	ICGC	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation rewiring degron network	0.1389
p.P2108S	DO234237	ESAD	ICGC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation altering degron motif	0.6752
p.I3639N	DO234270	ESAD	ICGC	PVSTT	DEG_SPOP_SBC_1	3641:3645	Mutation rewiring degron network	0.2778
p.P345L	DO10858	ESAD	ICGC	LTSTPAST	DEG_SCF_FBW7_1	336:343	Mutation rewiring degron network	0.2778
p.P345L	DO10858	ESAD	ICGC	PLTST	DEG_SPOP_SBC_1	335:339	Mutation rewiring degron network	0.1667
p.T199I	DO234321	ESAD	ICGC	MSTPLTT	DEG_SCF_FBW7_1	184:190	Mutation rewiring degron network	0.0833
p.T199I	DO234321	ESAD	ICGC	PLTTS	DEG_SPOP_SBC_1	187:191	Mutation rewiring degron network	0.1111
p.T199I	DO234321	ESAD	ICGC	PESTT	DEG_SPOP_SBC_1	201:205	Mutation rewiring degron network	0.2778
p.G450V	DO234369	ESAD	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation rewiring degron network	0.0833
p.G450V	DO234369	ESAD	ICGC	PVSTT	DEG_SPOP_SBC_1	458:462	Mutation rewiring degron network	0.1111
p.T1640N	DO234284	ESAD	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation altering degron motif	0.5944
p.S928G	DO234281	ESAD	ICGC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.2778
p.T1699I	DO48308	ESCA	ICGC	VRTTPVAS	DEG_SCF_FBW7_1	1697:1704	Mutation altering degron motif	0.5966
p.T3458A	DO223009	ESCA	ICGC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.1944
p.T3458A	DO223009	ESCA	ICGC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.1667
p.S643N	DO223140	ESCA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.1667
p.T3809M	DO222570	ESCA	ICGC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation altering degron motif	0.7423
p.T3809M	SIDM01709	Melanoma	GDSC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation altering degron motif	0.7423
p.T3809M	ACH-000275	Non-Cancerous	CCLE	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation altering degron motif	0.7423
p.S1495C	DO222754	ESCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1491:1495	Mutation altering degron motif	0.7541
p.T3115K	DO228515	GACA	ICGC	PVSTT	DEG_SPOP_SBC_1	3111:3115	Mutation altering degron motif	0.7306
p.A2473S	DO228615	GACA	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1389
p.T3938A	DO228732	GACA	ICGC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.25
p.T3938A	DO228732	GACA	ICGC	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation rewiring degron network	0.1389
p.T3938A	DO42673	UCEC	ICGC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.25
p.T3938A	DO42673	UCEC	ICGC	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation rewiring degron network	0.1389
p.P2716A	DO228761	GACA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2712:2719	Mutation altering degron motif	0.7503
p.S656T	DO228791	GACA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation altering degron motif	0.6005
p.S656T	DO227496	LAML	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation altering degron motif	0.6005
p.S656T	DO228905	LICA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation altering degron motif	0.6005
p.S656T	DO228926	LICA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation altering degron motif	0.6005
p.S656T	DO228941	LICA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation altering degron motif	0.6005
p.S656T	DO228950	LICA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation altering degron motif	0.6005
p.T4056A	DO233170	GACA	ICGC	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation rewiring degron network	0.1667
p.T3694A	DO233652	GACA	ICGC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.1667
p.P2108H	DO233624	GACA	ICGC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation altering degron motif	0.7694
p.T1331S	DO233702	GACA	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.2222
p.V3946I	DO233731	GACA	ICGC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation altering degron motif	0.5965
p.V3946I	DO233731	GACA	ICGC	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation altering degron motif	0.5965
p.P458L	DO233882	GACA	ICGC	PVSTT	DEG_SPOP_SBC_1	458:462	Mutation altering degron motif	0.7582
p.V3965L	DO233828	GACA	ICGC	VSTPVIT	DEG_SCF_FBW7_1	3961:3967	Mutation altering degron motif	0.5654
p.V3965L	DO233828	GACA	ICGC	VITST	DEG_SPOP_SBC_1	3965:3969	Mutation altering degron motif	0.6765
p.S702I	DO233857	GACA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	708:715	Mutation rewiring degron network	0.1667
p.R4043H	DO233935	GACA	ICGC	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation rewiring degron network	0.3056
p.R4043H	DO233935	GACA	ICGC	PHTST	DEG_SPOP_SBC_1	4034:4038	Mutation rewiring degron network	0.1944
p.A378T	DO11854	GBM	ICGC	VTTST	DEG_SPOP_SBC_1	365:369	Mutation rewiring degron network	0.0833
p.R1728C	DO14232	HNSC	ICGC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.2222
p.T1159I	DO230659	LAML	ICGC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1389
p.T1159I	DO231140	LAML	ICGC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1389
p.T1159I	DO228941	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1389
p.T1159I	DO228947	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1389
p.A3186T	DO227501	LAML	ICGC	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.1111
p.H3143N	DO227496	LAML	ICGC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.2222
p.H3143N	DO229060	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.2222
p.G2828S	DO227496	LAML	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.2778
p.G2828S	DO227496	LAML	ICGC	VDTST	DEG_SPOP_SBC_1	2835:2839	Mutation rewiring degron network	0.1389
p.G2828S	DO228946	LICA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.2778
p.G2828S	DO228946	LICA	ICGC	VDTST	DEG_SPOP_SBC_1	2835:2839	Mutation rewiring degron network	0.1389
p.G2828S	DO228960	LICA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.2778
p.G2828S	DO228960	LICA	ICGC	VDTST	DEG_SPOP_SBC_1	2835:2839	Mutation rewiring degron network	0.1389
p.G2828S	DO229029	LICA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.2778
p.G2828S	DO229029	LICA	ICGC	VDTST	DEG_SPOP_SBC_1	2835:2839	Mutation rewiring degron network	0.1389
p.G2828S	DO229051	LICA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.2778
p.G2828S	DO229051	LICA	ICGC	VDTST	DEG_SPOP_SBC_1	2835:2839	Mutation rewiring degron network	0.1389
p.G2828S	DO229053	LICA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.2778
p.G2828S	DO229053	LICA	ICGC	VDTST	DEG_SPOP_SBC_1	2835:2839	Mutation rewiring degron network	0.1389
p.G2828S	DO229056	LICA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.2778
p.G2828S	DO229056	LICA	ICGC	VDTST	DEG_SPOP_SBC_1	2835:2839	Mutation rewiring degron network	0.1389
p.G2828S	DO45251	LIRI	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.2778
p.G2828S	DO45251	LIRI	ICGC	VDTST	DEG_SPOP_SBC_1	2835:2839	Mutation rewiring degron network	0.1389
p.G2828S	DO232656	PBCA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.2778
p.G2828S	DO232656	PBCA	ICGC	VDTST	DEG_SPOP_SBC_1	2835:2839	Mutation rewiring degron network	0.1389
p.A2257V	DO49675	LIAD	ICGC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.0556
p.A2257V	DO49675	LIAD	ICGC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.25
p.A2257V	DO22802	LICA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.0556
p.A2257V	DO22802	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.25
p.E1393D	DO228299	LICA	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.0556
p.E1393D	DO228299	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.0833
p.S3064R	DO228264	LICA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.2778
p.S3064R	DO228264	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.1111
p.T3382K	DO228508	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation rewiring degron network	0.1111
p.T1899A	DO228531	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.25
p.T1899A	DO228650	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.25
p.T1899I	DO228531	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.25
p.T1899I	DO228650	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.25
p.V1904A	DO228828	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1111
p.R1922S	DO228828	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.0556
p.R1922S	DO228291	MALY	ICGC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.0556
p.N657S	DO228905	LICA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.3056
p.N657S	DO228905	LICA	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.0833
p.N657S	DO228926	LICA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.3056
p.N657S	DO228926	LICA	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.0833
p.N657S	DO228338	MALY	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.3056
p.N657S	DO228338	MALY	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.0833
p.V2469A	DO228934	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.25
p.V2469A	DO228937	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.25
p.V2469A	DO229030	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.25
p.S2471P	DO228937	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1944
p.P1343T	DO228941	LICA	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.5919
p.S1381A	DO228943	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.0556
p.A946T	DO228943	LICA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation altering degron motif	0.6028
p.A946T	DO229004	LICA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation altering degron motif	0.6028
p.T962S	DO228943	LICA	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.0833
p.T962S	DO228943	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.2222
p.T962S	DO228948	LICA	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.0833
p.T962S	DO228948	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.2222
p.T962S	DO229030	LICA	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.0833
p.T962S	DO229030	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.2222
p.T962S	DO229053	LICA	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.0833
p.T962S	DO229053	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.2222
p.V2547I	DO228945	LICA	ICGC	VVTST	DEG_SPOP_SBC_1	2546:2550	Mutation altering degron motif	0.5965
p.V3416A	DO228944	LICA	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.25
p.L3429P	DO228944	LICA	ICGC	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.3056
p.N3417S	DO228944	LICA	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.2222
p.S2873I	DO228948	LICA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.25
p.S3472I	DO228948	LICA	ICGC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.2222
p.A3559S	DO228948	LICA	ICGC	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.1389
p.T2455S	DO228950	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1389
p.T2455S	DO229030	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1389
p.I307T	DO228950	LICA	ICGC	VITST	DEG_SPOP_SBC_1	306:310	Mutation altering degron motif	0.5966
p.T658S	DO228950	LICA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.2778
p.T658S	DO228950	LICA	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.1111
p.P1498T	DO228950	LICA	ICGC	AVSSS	DEG_SPOP_SBC_1	1491:1495	Mutation rewiring degron network	0.25
p.P1498T	DO229057	LICA	ICGC	AVSSS	DEG_SPOP_SBC_1	1491:1495	Mutation rewiring degron network	0.25
p.P3717T	DO228950	LICA	ICGC	VTSTPVTT	DEG_SCF_FBW7_1	3720:3727	Mutation rewiring degron network	0.25
p.P3717T	DO228950	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	3724:3728	Mutation rewiring degron network	0.1389
p.I1754M	DO228950	LICA	ICGC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation rewiring degron network	0.2778
p.I1754M	DO228950	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.3056
p.I1754M	DO229030	LICA	ICGC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation rewiring degron network	0.2778
p.I1754M	DO229030	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.3056
p.N1364T	DO228950	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.25
p.N1364T	DO229052	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.25
p.N1364T	DO229057	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.25
p.A3471V	DO228950	LICA	ICGC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.25
p.V3542A	DO228848	LICA	ICGC	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.1667
p.S1090C	DO228863	LICA	ICGC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.1389
p.S1734A	DO228862	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.0556
p.M3404I	DO228967	LICA	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.2778
p.M3404I	DO229052	LICA	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.2778
p.M3404I	DO229061	LICA	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.2778
p.S549T	DO228967	LICA	ICGC	ASSSS	DEG_SPOP_SBC_1	548:552	Mutation altering degron motif	0.6005
p.L1171P	DO228967	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.3056
p.R2160S	DO228960	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.1389
p.R2160S	DO229030	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.1389
p.S546T	DO228960	LICA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation rewiring degron network	0.1111
p.S546T	DO228960	LICA	ICGC	VDTST	DEG_SPOP_SBC_1	536:540	Mutation rewiring degron network	0.1667
p.S546T	DO228960	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	541:545	Mutation rewiring degron network	0.3056
p.S546T	DO228960	LICA	ICGC	ASSSS	DEG_SPOP_SBC_1	548:552	Mutation rewiring degron network	0.2778
p.S546T	DO229055	LICA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation rewiring degron network	0.1111
p.S546T	DO229055	LICA	ICGC	VDTST	DEG_SPOP_SBC_1	536:540	Mutation rewiring degron network	0.1667
p.S546T	DO229055	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	541:545	Mutation rewiring degron network	0.3056
p.S546T	DO229055	LICA	ICGC	ASSSS	DEG_SPOP_SBC_1	548:552	Mutation rewiring degron network	0.2778
p.T1748S	DO228960	LICA	ICGC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation rewiring degron network	0.1111
p.T1748S	DO228960	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.1389
p.T2258S	DO228960	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.2222
p.T2258S	DO228998	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.2222
p.T2258S	DO229056	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.2222
p.S1139T	DO228960	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.2222
p.P2117S	DO228960	LICA	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.3056
p.P2117S	DO228960	LICA	ICGC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.S2884P	DO228960	LICA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.3056
p.S2884P	SIDM02064	Colorectal Carcinoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.3056
p.V3130A	DO228960	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.1944
p.V1368L	DO228974	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation altering degron motif	0.5654
p.A1138S	DO228978	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.25
p.A607S	DO228971	LICA	ICGC	ASSSS	DEG_SPOP_SBC_1	607:611	Mutation altering degron motif	0.7588
p.S2544I	DO229018	LICA	ICGC	VVTST	DEG_SPOP_SBC_1	2546:2550	Mutation rewiring degron network	0.2778
p.A2847S	DO229018	LICA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.A2847S	DO229018	LICA	ICGC	VDTST	DEG_SPOP_SBC_1	2835:2839	Mutation rewiring degron network	0.1111
p.A2847S	DO229018	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation rewiring degron network	0.25
p.A642S	DO229019	LICA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.1389
p.A1902S	DO229015	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1667
p.L3816F	DO229029	LICA	ICGC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.1389
p.S4032I	DO229028	LICA	ICGC	PHTST	DEG_SPOP_SBC_1	4034:4038	Mutation rewiring degron network	0.2778
p.T4027M	DO229022	LICA	ICGC	PSTPRTT	DEG_SCF_FBW7_1	4011:4017	Mutation rewiring degron network	0.0556
p.T4027M	DO229022	LICA	ICGC	PRTTS	DEG_SPOP_SBC_1	4014:4018	Mutation rewiring degron network	0.0833
p.T4027M	DO229022	LICA	ICGC	PHTST	DEG_SPOP_SBC_1	4034:4038	Mutation rewiring degron network	0.1389
p.S3466I	DO229025	LICA	ICGC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation altering degron motif	0.7341
p.S1619I	DO229027	LICA	ICGC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.1944
p.D3952Y	DO229027	LICA	ICGC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.2222
p.D3952Y	DO229027	LICA	ICGC	VSTPVIT	DEG_SCF_FBW7_1	3961:3967	Mutation rewiring degron network	0.0833
p.D3952Y	DO229027	LICA	ICGC	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation rewiring degron network	0.25
p.A4144S	DO229026	LICA	ICGC	PRTTT	DEG_SPOP_SBC_1	4130:4134	Mutation rewiring degron network	0.0556
p.S670P	DO229030	LICA	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation altering degron motif	0.6752
p.I1636M	DO229030	LICA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation rewiring degron network	0.2778
p.N1717T	DO229030	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.25
p.N1717T	DO229053	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.25
p.N1717T	DO229057	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.25
p.T3202S	DO229030	LICA	ICGC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation altering degron motif	0.6005
p.I3212M	DO229030	LICA	ICGC	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation rewiring degron network	0.0833
p.I3212M	DO229030	LICA	ICGC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.1389
p.N471T	DO229030	LICA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation rewiring degron network	0.1944
p.N471T	DO229030	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	458:462	Mutation rewiring degron network	0.0833
p.V1173A	DO229030	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.25
p.V1173A	DO228349	MALY	ICGC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.25
p.V1173A	ACH-000091	Ovarian Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.25
p.V1173A	OV-56	ovary	COSMIC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.25
p.R2342S	DO229030	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.2778
p.G3109S	DO229030	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	3111:3115	Mutation rewiring degron network	0.2778
p.G3109S	DO229061	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	3111:3115	Mutation rewiring degron network	0.2778
p.S2169I	DO229034	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation altering degron motif	0.7341
p.A2736S	DO229034	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	2722:2726	Mutation rewiring degron network	0.0556
p.M3806I	DO229036	LICA	ICGC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation altering degron motif	0.6507
p.M3806I	SIDM01126	Small Cell Lung Carcinoma	GDSC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation altering degron motif	0.6507
p.M3806I	SIDM00846	Cervical Carcinoma	GDSC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation altering degron motif	0.6507
p.M3806I	SIDM00633	Breast Carcinoma	GDSC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation altering degron motif	0.6507
p.G3692V	DO229035	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.1111
p.S3978I	DO229038	LICA	ICGC	PSTSS	DEG_SPOP_SBC_1	3974:3978	Mutation altering degron motif	0.7341
p.S313T	DO229050	LICA	ICGC	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.25
p.A2882V	DO229050	LICA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.5825
p.R1336S	DO229052	LICA	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.7427
p.I1342M	DO229052	LICA	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.6507
p.C1375S	DO229052	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.2222
p.T1622P	DO229052	LICA	ICGC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.1111
p.P1701L	DO229052	LICA	ICGC	VRTTPVAS	DEG_SCF_FBW7_1	1697:1704	Mutation altering degron motif	0.7582
p.P1701L	DO22860	LIHC	ICGC	VRTTPVAS	DEG_SCF_FBW7_1	1697:1704	Mutation altering degron motif	0.7582
p.A1771T	DO229052	LICA	ICGC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation altering degron motif	0.6028
p.S3045T	DO229052	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.1389
p.I1623T	DO229052	LICA	ICGC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.0833
p.I3051M	DO229052	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.3056
p.I3051M	ACH-002272	Lymphoma	CCLE	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.3056
p.I3051M	MHH-PREB-1	haematopoietic and lymphoid tissue	COSMIC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.3056
p.L3379S	DO229052	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation rewiring degron network	0.1944
p.M521T	DO229051	LICA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation rewiring degron network	0.0556
p.I560M	DO229053	LICA	ICGC	ASSSS	DEG_SPOP_SBC_1	548:552	Mutation rewiring degron network	0.1111
p.I560M	DO229055	LICA	ICGC	ASSSS	DEG_SPOP_SBC_1	548:552	Mutation rewiring degron network	0.1111
p.A968S	DO229058	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.0556
p.T1372S	DO229058	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.3056
p.I1636V	DO229058	LICA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation rewiring degron network	0.2778
p.T1395S	DO229057	LICA	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.1111
p.T1395S	DO229057	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1389
p.T1395S	SIDM01180	Hepatocellular Carcinoma	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.1111
p.T1395S	SIDM01180	Hepatocellular Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1389
p.T1395S	SNU-387	liver	COSMIC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.1111
p.T1395S	SNU-387	liver	COSMIC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.1389
p.I3060S	DO229057	LICA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.1667
p.I3060S	DO229057	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation rewiring degron network	0.2222
p.G3513S	DO229057	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	3523:3527	Mutation rewiring degron network	0.0556
p.N1178S	DO229057	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1111
p.N1178S	DO229060	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1111
p.N1178S	DO228375	MALY	ICGC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.1111
p.V288A	DO229057	LICA	ICGC	TRMPLSVML	DEG_APCC_DBOX_1	278:286	Mutation rewiring degron network	0.2778
p.V288A	DO229057	LICA	ICGC	LSTTPAAT	DEG_SCF_FBW7_1	295:302	Mutation rewiring degron network	0.1389
p.S1619T	DO229057	LICA	ICGC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.1944
p.L2870P	DO229061	LICA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.1667
p.T2124A	DO229060	LICA	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.1111
p.H3143R	DO229060	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.2222
p.M3522I	DO229060	LICA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation rewiring degron network	0.2778
p.M3522I	DO229060	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	3523:3527	Mutation rewiring degron network	0.3056
p.T2367I	DO229062	LICA	ICGC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.2778
p.P3528L	DO229062	LICA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation altering degron motif	0.7582
p.P3528L	SIDM00510	Small Cell Lung Carcinoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation altering degron motif	0.7582
p.P3528L	SIDM01110	Hepatocellular Carcinoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation altering degron motif	0.7582
p.P3528L	SIDM00265	Ewing's Sarcoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation altering degron motif	0.7582
p.P3528L	SIDM00939	Non-Small Cell Lung Carcinoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation altering degron motif	0.7582
p.A2119S	DO229009	LICA	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.25
p.A2119S	DO229009	LICA	ICGC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1389
p.T1543A	DO44676	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation altering degron motif	0.7139
p.P305L	DO231909	LINC	ICGC	LSTTPAAT	DEG_SCF_FBW7_1	295:302	Mutation rewiring degron network	0.25
p.P305L	DO231909	LINC	ICGC	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.3056
p.D1245V	DO23498	LINC	ICGC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.0833
p.D596Y	DO23396	LINC	ICGC	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation rewiring degron network	0.1944
p.D596Y	DO23396	LINC	ICGC	VTTSS	DEG_SPOP_SBC_1	601:605	Mutation rewiring degron network	0.1944
p.G3515R	DO45237	LIRI	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation rewiring degron network	0.0833
p.G3515R	DO45237	LIRI	ICGC	PVSTT	DEG_SPOP_SBC_1	3523:3527	Mutation rewiring degron network	0.1111
p.S2352C	DO48715	LIRI	ICGC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.1667
p.S2352C	DO48715	LIRI	ICGC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.2222
p.N657D	DO48701	LIRI	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	649:656	Mutation rewiring degron network	0.3056
p.N657D	DO48701	LIRI	ICGC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.0833
p.T2105A	DO51576	LUSC	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.2222
p.T2105A	DO51576	LUSC	ICGC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.25
p.E2118V	DO230530	LUSC	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.2778
p.E2118V	DO230530	LUSC	ICGC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1667
p.T2355K	DO230968	LUSC	ICGC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.25
p.T2355K	DO230968	LUSC	ICGC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1389
p.T2355K	DO224621	LUSC	ICGC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.25
p.T2355K	DO224621	LUSC	ICGC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1389
p.A465V	DO230990	LUSC	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation altering degron motif	0.5825
p.A465V	DO224554	LUSC	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation altering degron motif	0.5825
p.T317I	DO224566	LUSC	ICGC	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.1389
p.T317I	DO231007	LUSC	ICGC	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.1389
p.A4088D	DO224610	LUSC	ICGC	ASSTT	DEG_SPOP_SBC_1	4079:4083	Mutation rewiring degron network	0.1944
p.T1696A	DO231072	LUSC	ICGC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.6028
p.A3318G	DO231075	LUSC	ICGC	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.0556
p.A3318G	DO231075	LUSC	ICGC	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation rewiring degron network	0.1111
p.E1942K	DO231075	LUSC	ICGC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.1667
p.P2851L	DO231104	LUSC	ICGC	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation rewiring degron network	0.1389
p.E1294Q	DO231132	LUSC	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.1667
p.E2060K	DO231207	LUSC	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation rewiring degron network	0.2222
p.E2060K	DO231207	LUSC	ICGC	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.1667
p.P2068T	DO231209	LUSC	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation altering degron motif	0.7031
p.A4030P	DO231204	LUSC	ICGC	PHTST	DEG_SPOP_SBC_1	4034:4038	Mutation rewiring degron network	0.2222
p.S2720C	DO27484	LUSC	ICGC	VDTST	DEG_SPOP_SBC_1	2717:2721	Mutation altering degron motif	0.7541
p.T2820M	DO27833	MALY	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM00926	Non-Small Cell Lung Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM00773	Non-Cancerous	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM01116	Non-Small Cell Lung Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM00967	Ovarian Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM00454	Rhabdomyosarcoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM00656	Burkitt's Lymphoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM00690	Head and Neck Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM01112	Osteosarcoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM00529	Breast Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM00844	Burkitt's Lymphoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM01133	Other Solid Cancers	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM01072	Squamous Cell Lung Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM00431	T-Lymphoblastic Leukemia	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM00863	Burkitt's Lymphoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM00721	Small Cell Lung Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM00118	Colorectal Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM00774	Breast Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM00257	Neuroblastoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM00673	Breast Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM00641	Burkitt's Lymphoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM01664	Prostate Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM01605	Non-Small Cell Lung Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM01710	Squamous Cell Lung Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.T2820M	SIDM01752	Pancreatic Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.0556
p.S3555I	DO228326	MALY	ICGC	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.25
p.A2727T	DO228349	MALY	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	2712:2719	Mutation rewiring degron network	0.1111
p.A2727T	DO228349	MALY	ICGC	VDTST	DEG_SPOP_SBC_1	2717:2721	Mutation rewiring degron network	0.1667
p.A2727T	DO228349	MALY	ICGC	PVTTS	DEG_SPOP_SBC_1	2722:2726	Mutation rewiring degron network	0.3056
p.A2727T	SK-UT-1	soft tissue	COSMIC	LSTTPVDT	DEG_SCF_FBW7_1	2712:2719	Mutation rewiring degron network	0.1111
p.A2727T	SK-UT-1	soft tissue	COSMIC	VDTST	DEG_SPOP_SBC_1	2717:2721	Mutation rewiring degron network	0.1667
p.A2727T	SK-UT-1	soft tissue	COSMIC	PVTTS	DEG_SPOP_SBC_1	2722:2726	Mutation rewiring degron network	0.3056
p.T1749P	DO228584	MALY	ICGC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation rewiring degron network	0.1389
p.T1749P	DO228584	MALY	ICGC	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.1667
p.A878P	DO220879	MELA	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.1389
p.E1432K	DO220875	MELA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	1416:1423	Mutation rewiring degron network	0.0833
p.E1432K	DO220875	MELA	ICGC	VDTST	DEG_SPOP_SBC_1	1421:1425	Mutation rewiring degron network	0.1389
p.E1432K	DO220875	MELA	ICGC	PGTTS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.2778
p.S526F	DO220877	MELA	ICGC	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation rewiring degron network	0.1944
p.S526F	DO220877	MELA	ICGC	VDTST	DEG_SPOP_SBC_1	536:540	Mutation rewiring degron network	0.0556
p.S196L	DO220877	MELA	ICGC	MSTPLTT	DEG_SCF_FBW7_1	184:190	Mutation rewiring degron network	0.1667
p.S196L	DO220877	MELA	ICGC	PLTTS	DEG_SPOP_SBC_1	187:191	Mutation rewiring degron network	0.1944
p.S196L	DO220877	MELA	ICGC	PESTT	DEG_SPOP_SBC_1	201:205	Mutation rewiring degron network	0.1944
p.P1338S	DO220882	MELA	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.5641
p.L295F	DO220886	MELA	ICGC	LSTTPAAT	DEG_SCF_FBW7_1	295:302	Mutation altering degron motif	0.6981
p.T2258I	DO220891	MELA	ICGC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.2222
p.S373L	DO220891	MELA	ICGC	VTTST	DEG_SPOP_SBC_1	365:369	Mutation rewiring degron network	0.2222
p.S373L	DO222837	MELA	ICGC	VTTST	DEG_SPOP_SBC_1	365:369	Mutation rewiring degron network	0.2222
p.P2102L	DO220907	MELA	ICGC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.1389
p.P2102L	DO220907	MELA	ICGC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1667
p.P325S	DO220907	MELA	ICGC	PLTST	DEG_SPOP_SBC_1	335:339	Mutation rewiring degron network	0.0556
p.S203N	DO220911	MELA	ICGC	PESTT	DEG_SPOP_SBC_1	201:205	Mutation altering degron motif	0.7069
p.P1498L	DO222395	MELA	ICGC	AVSSS	DEG_SPOP_SBC_1	1491:1495	Mutation rewiring degron network	0.25
p.E3970K	DO222494	MELA	ICGC	VSTPVIT	DEG_SCF_FBW7_1	3961:3967	Mutation rewiring degron network	0.25
p.E3970K	DO222494	MELA	ICGC	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation rewiring degron network	0.3056
p.E3970K	DO222494	MELA	ICGC	VITST	DEG_SPOP_SBC_1	3965:3969	Mutation rewiring degron network	0.3056
p.E3970K	DO222494	MELA	ICGC	PSTSS	DEG_SPOP_SBC_1	3974:3978	Mutation rewiring degron network	0.2222
p.T3814I	DO222402	MELA	ICGC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.1944
p.P3459L	DO222521	MELA	ICGC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.1667
p.P3459L	DO222521	MELA	ICGC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.1944
p.S545F	DO222527	MELA	ICGC	PVTTS	DEG_SPOP_SBC_1	541:545	Mutation altering degron motif	0.7982
p.T2773K	DO222527	MELA	ICGC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation rewiring degron network	0.1111
p.S3420L	DO222653	MELA	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.1389
p.S3420L	DO222653	MELA	ICGC	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.0556
p.S550L	DO222662	MELA	ICGC	ASSSS	DEG_SPOP_SBC_1	548:552	Mutation altering degron motif	0.7667
p.S550L	DO229453	SKCA	ICGC	ASSSS	DEG_SPOP_SBC_1	548:552	Mutation altering degron motif	0.7667
p.E1530K	DO222749	MELA	ICGC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.2222
p.E1530K	DO222749	MELA	ICGC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0833
p.V2540I	DO222714	MELA	ICGC	VVTST	DEG_SPOP_SBC_1	2546:2550	Mutation rewiring degron network	0.1667
p.G2867R	DO222868	MELA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.0833
p.S1122F	DO222875	MELA	ICGC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.0833
p.T1596I	DO222880	MELA	ICGC	LSTTPIDS	DEG_SCF_FBW7_1	1593:1600	Mutation altering degron motif	0.7078
p.S212N	DO222837	MELA	ICGC	PESTT	DEG_SPOP_SBC_1	201:205	Mutation blocking phosphorylation signal	0.5833
p.P1701S	DO222837	MELA	ICGC	VRTTPVAS	DEG_SCF_FBW7_1	1697:1704	Mutation altering degron motif	0.6752
p.A587T	DO222837	MELA	ICGC	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation altering degron motif	0.7139
p.S3414Y	DO46588	OV	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.3056
p.S3309N	DO49185	PACA	ICGC	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation altering degron motif	0.7069
p.S3309N	DO232761	PBCA	ICGC	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation altering degron motif	0.7069
p.V3077L	DO49185	PACA	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.2222
p.D3190E	DO32908	PACA	ICGC	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.2222
p.R864S	DO49451	PACA	ICGC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation altering degron motif	0.7427
p.A2264V	DO232761	PBCA	ICGC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.0556
p.T1069P	DO232823	PBCA	ICGC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.0556
p.P1338T	DO232224	PBCA	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.5919
p.S3538L	DO51050	PRAD	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation rewiring degron network	0.1389
p.S3538L	DO51050	PRAD	ICGC	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.0556
p.T3797A	DO36556	READ	ICGC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.1111
p.P2875S	DO47243	RECA	ICGC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.3056
p.P187L	DO47174	RECA	ICGC	MSTPLTT	DEG_SCF_FBW7_1	184:190	Mutation altering degron motif	0.7582
p.P187L	DO47174	RECA	ICGC	PLTTS	DEG_SPOP_SBC_1	187:191	Mutation altering degron motif	0.7582
p.E2551G	DO46909	RECA	ICGC	VVTST	DEG_SPOP_SBC_1	2546:2550	Mutation rewiring degron network	0.3056
p.M1327I	DO46980	RECA	ICGC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.1111
p.S3320L	DO219879	SKCA	ICGC	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation rewiring degron network	0.0556
p.S1082F	DO229459	SKCA	ICGC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation altering degron motif	0.7982
p.G4137E	DO229456	SKCA	ICGC	PRTTT	DEG_SPOP_SBC_1	4130:4134	Mutation rewiring degron network	0.25
p.E1275K	DO229456	SKCA	ICGC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.2778
p.E1275K	DO229456	SKCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.0833
p.V949I	DO229462	SKCA	ICGC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation altering degron motif	0.5965
p.V949I	DO229462	SKCA	ICGC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation altering degron motif	0.7076
p.G1924E	DO218912	SKCA	ICGC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.1111
p.L1762V	DO218868	SKCA	ICGC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation altering degron motif	0.5654
p.T2455I	DO218863	SKCA	ICGC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1389
p.P1485L	DO218856	SKCA	ICGC	AVSSS	DEG_SPOP_SBC_1	1491:1495	Mutation rewiring degron network	0.1667
p.T1733A	DO218847	SKCA	ICGC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.0833
p.P3423S	DO218847	SKCA	ICGC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.0556
p.P3423S	DO218847	SKCA	ICGC	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.1389
p.V3083I	DO37659	SKCM	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation rewiring degron network	0.0556
p.F4136L	DO229224	THCA	ICGC	PRTTT	DEG_SPOP_SBC_1	4130:4134	Mutation rewiring degron network	0.2778
p.I416T	DO231475	THCA	ICGC	ASTTS	DEG_SPOP_SBC_1	410:414	Mutation rewiring degron network	0.2778
p.L826I	DO42673	UCEC	ICGC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation altering degron motif	0.6063
p.M678T	SIDM02050	Colorectal Carcinoma	GDSC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.1111
p.S1156N	SIDM01314	Colorectal Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.0556
p.P2113L	SIDM01308	Esophageal Carcinoma	GDSC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.7582
p.P2113L	SIDM00344	Non-Small Cell Lung Carcinoma	GDSC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.7582
p.P2113L	LCLC-97TM1	lung	COSMIC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation altering degron motif	0.7582
p.S1482C	SIDM02014	Esophageal Carcinoma	GDSC	AVSSS	DEG_SPOP_SBC_1	1491:1495	Mutation rewiring degron network	0.0833
p.S1724F	SIDM01163	Non-Small Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation altering degron motif	0.7982
p.S1724F	ACH-000677	Lung Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation altering degron motif	0.7982
p.S1724F	SW1573	lung	COSMIC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation altering degron motif	0.7982
p.A300T	SIDM00578	Neuroblastoma	GDSC	LSTTPAAT	DEG_SCF_FBW7_1	295:302	Mutation altering degron motif	0.6028
p.A300T	ACH-000804	Neuroblastoma	CCLE	LSTTPAAT	DEG_SCF_FBW7_1	295:302	Mutation altering degron motif	0.6028
p.T3373N	SIDM01068	Non-Small Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00074	Burkitt's Lymphoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM01123	Prostate Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00521	Small Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM01058	B-Cell Non-Hodgkin's Lymphoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM01004	Chronic Myelogenous Leukemia	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM01020	Plasma Cell Myeloma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00884	Breast Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00962	Chronic Myelogenous Leukemia	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00113	Kidney Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00495	B-Cell Non-Hodgkin's Lymphoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00602	Gastric Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM01199	Hepatocellular Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00099	Mesothelioma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00660	Colorectal Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00328	Esophageal Squamous Cell Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00040	Gastric Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00194	Colorectal Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00260	Gastric Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00687	Gastric Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00694	Other Solid Cancers	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00047	Non-Small Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00963	Breast Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00421	T-Cell Non-Hodgkin's Lymphoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00910	Neuroblastoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00888	Other Solid Cancers	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00651	Non-Small Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00775	Non-Small Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00883	Non-Cancerous	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00958	Chronic Myelogenous Leukemia	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00837	Colorectal Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00280	Gastric Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00397	Acute Myeloid Leukemia	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00097	Breast Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00428	Acute Myeloid Leukemia	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00956	Esophageal Squamous Cell Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00261	Ewing's Sarcoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00628	Breast Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM01609	Endometrial Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM01624	Bladder Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM01608	Endometrial Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM01780	B-Cell Non-Hodgkin's Lymphoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM01578	Bladder Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM01689	B-Lymphoblastic Leukemia	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00008	Ovarian Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM00170	Head and Neck Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM01409	Bladder Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM01776	Plasma Cell Myeloma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM01758	B-Cell Non-Hodgkin's Lymphoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM01435	Hepatocellular Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM01690	Plasma Cell Myeloma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM01696	Mesothelioma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM01677	Non-Small Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T3373N	SIDM01254	Burkitt's Lymphoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7055
p.T2255A	SIDM00435	Acute Myeloid Leukemia	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00435	Acute Myeloid Leukemia	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM00434	Plasma Cell Myeloma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00434	Plasma Cell Myeloma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM00373	Endometrial Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00373	Endometrial Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM00611	Kidney Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00611	Kidney Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM01175	Other Sarcomas	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM01175	Other Sarcomas	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM00993	Plasma Cell Myeloma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00993	Plasma Cell Myeloma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM01036	Plasma Cell Myeloma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM01036	Plasma Cell Myeloma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM01005	Acute Myeloid Leukemia	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM01005	Acute Myeloid Leukemia	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM00569	Osteosarcoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00569	Osteosarcoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM00354	Squamous Cell Lung Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00354	Squamous Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM00350	Head and Neck Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00350	Head and Neck Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM00955	Melanoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00955	Melanoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM00391	Plasma Cell Myeloma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00391	Plasma Cell Myeloma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM00259	Neuroblastoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00259	Neuroblastoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM00085	Glioma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00085	Glioma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM01068	Non-Small Cell Lung Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM01068	Non-Small Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM00276	Biliary Tract Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00276	Biliary Tract Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM00672	Hepatocellular Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00672	Hepatocellular Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM00049	Colorectal Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00049	Colorectal Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM00476	Ovarian Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00476	Ovarian Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM00997	Thyroid Gland Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00997	Thyroid Gland Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM00794	Other Solid Cancers	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00794	Other Solid Cancers	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM00574	Glioblastoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00574	Glioblastoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM01191	Osteosarcoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM01191	Osteosarcoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM01074	Glioblastoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM01074	Glioblastoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM00273	Glioblastoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM00273	Glioblastoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM01628	Non-Small Cell Lung Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM01628	Non-Small Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM01598	Non-Small Cell Lung Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM01598	Non-Small Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM01510	Non-Small Cell Lung Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM01510	Non-Small Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.T2255A	SIDM01690	Plasma Cell Myeloma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.1111
p.T2255A	SIDM01690	Plasma Cell Myeloma	GDSC	PVTTS	DEG_SPOP_SBC_1	2250:2254	Mutation rewiring degron network	0.3056
p.P2117L	SIDM00321	Ovarian Carcinoma	GDSC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.3056
p.P2117L	SIDM00321	Ovarian Carcinoma	GDSC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.P2117L	SIDM00315	Glioblastoma	GDSC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.3056
p.P2117L	SIDM00315	Glioblastoma	GDSC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.P2117L	SIDM00296	Small Cell Lung Carcinoma	GDSC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.3056
p.P2117L	SIDM00296	Small Cell Lung Carcinoma	GDSC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.P2117L	SIDM00360	Other Solid Cancers	GDSC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.3056
p.P2117L	SIDM00360	Other Solid Cancers	GDSC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.P2117L	SIDM00249	Esophageal Squamous Cell Carcinoma	GDSC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.3056
p.P2117L	SIDM00249	Esophageal Squamous Cell Carcinoma	GDSC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.P2117L	SIDM01027	Esophageal Squamous Cell Carcinoma	GDSC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.3056
p.P2117L	SIDM01027	Esophageal Squamous Cell Carcinoma	GDSC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.P2117L	SIDM00380	Acute Myeloid Leukemia	GDSC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.3056
p.P2117L	SIDM00380	Acute Myeloid Leukemia	GDSC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.P2117L	SIDM00877	Breast Carcinoma	GDSC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.3056
p.P2117L	SIDM00877	Breast Carcinoma	GDSC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.P2117L	SIDM01335	Kidney Carcinoma	GDSC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.3056
p.P2117L	SIDM01335	Kidney Carcinoma	GDSC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.P2117L	SIDM01526	Mesothelioma	GDSC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.3056
p.P2117L	SIDM01526	Mesothelioma	GDSC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.P2117L	TYK-nu	ovary	COSMIC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.3056
p.P2117L	TYK-nu	ovary	COSMIC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.P2117L	QGP-1	pancreas	COSMIC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.3056
p.P2117L	QGP-1	pancreas	COSMIC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.P2117L	YKG-1	central nervous system	COSMIC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.3056
p.P2117L	YKG-1	central nervous system	COSMIC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.P2117L	TE-15	oesophagus	COSMIC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.3056
p.P2117L	TE-15	oesophagus	COSMIC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.P2117L	HCC1599	breast	COSMIC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.3056
p.P2117L	HCC1599	breast	COSMIC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.P2117L	KYSE-450	oesophagus	COSMIC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.3056
p.P2117L	KYSE-450	oesophagus	COSMIC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.P2117L	LU-134-A	lung	COSMIC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.3056
p.P2117L	LU-134-A	lung	COSMIC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.P2117L	SKM-1	haematopoietic and lymphoid tissue	COSMIC	LSTTPVAS	DEG_SCF_FBW7_1	2109:2116	Mutation rewiring degron network	0.3056
p.P2117L	SKM-1	haematopoietic and lymphoid tissue	COSMIC	PLSTT	DEG_SPOP_SBC_1	2108:2112	Mutation rewiring degron network	0.1944
p.T1782I	SIDM00407	B-Cell Non-Hodgkin's Lymphoma	GDSC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.1667
p.T1782I	ACH-000611	Lymphoma	CCLE	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.1667
p.P3052S	SIDM00608	Plasma Cell Myeloma	GDSC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation altering degron motif	0.6752
p.P3052S	ACH-000714	Myeloma	CCLE	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation altering degron motif	0.6752
p.P3052S	KMS-11	haematopoietic and lymphoid tissue	COSMIC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation altering degron motif	0.6752
p.T590S	SIDM00403	T-Lymphoblastic Leukemia	GDSC	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation altering degron motif	0.6005
p.T590S	RPMI-8402	haematopoietic and lymphoid tissue	COSMIC	ASTTS	DEG_SPOP_SBC_1	587:591	Mutation altering degron motif	0.6005
p.E2472D	SIDM01156	Small Cell Lung Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1667
p.E2472D	ACH-000890	Lung Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1667
p.E2472D	SW1271	lung	COSMIC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1667
p.A1431T	SIDM00884	Breast Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	1416:1423	Mutation rewiring degron network	0.1111
p.A1431T	SIDM00884	Breast Carcinoma	GDSC	VDTST	DEG_SPOP_SBC_1	1421:1425	Mutation rewiring degron network	0.1667
p.A1431T	SIDM00884	Breast Carcinoma	GDSC	PGTTS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.3056
p.R1925M	SIDM00216	Colorectal Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.1389
p.R1925M	ACH-000989	Colon/Colorectal Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.1389
p.R1925M	SNU-175	large intestine	COSMIC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.1389
p.T2355I	SIDM00762	Non-Small Cell Lung Carcinoma	GDSC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.25
p.T2355I	SIDM00762	Non-Small Cell Lung Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1389
p.T2355I	SIDM01652	Non-Cancerous	GDSC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.25
p.T2355I	SIDM01652	Non-Cancerous	GDSC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1389
p.T2355I	SIDM00266	Ewing's Sarcoma	GDSC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.25
p.T2355I	SIDM00266	Ewing's Sarcoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1389
p.T2355I	SIDM01161	Other Sarcomas	GDSC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.25
p.T2355I	SIDM01161	Other Sarcomas	GDSC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1389
p.T2355I	SIDM00899	Pancreatic Carcinoma	GDSC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.25
p.T2355I	SIDM00899	Pancreatic Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1389
p.T2355I	SIDM00223	Small Cell Lung Carcinoma	GDSC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.25
p.T2355I	SIDM00223	Small Cell Lung Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1389
p.T2355I	SIDM00853	Other Sarcomas	GDSC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.25
p.T2355I	SIDM00853	Other Sarcomas	GDSC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1389
p.T2355I	SIDM00836	Colorectal Carcinoma	GDSC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.25
p.T2355I	SIDM00836	Colorectal Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1389
p.T2355I	SIDM00063	Melanoma	GDSC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.25
p.T2355I	SIDM00063	Melanoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1389
p.T2355I	SIDM01107	Melanoma	GDSC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.25
p.T2355I	SIDM01107	Melanoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1389
p.T2355I	SIDM01193	Glioma	GDSC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.25
p.T2355I	SIDM01193	Glioma	GDSC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1389
p.T2355I	SIDM01757	Bladder Carcinoma	GDSC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.25
p.T2355I	SIDM01757	Bladder Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1389
p.T2355I	SIDM01775	B-Cell Non-Hodgkin's Lymphoma	GDSC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.25
p.T2355I	SIDM01775	B-Cell Non-Hodgkin's Lymphoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1389
p.T2355I	SIDM01566	Hodgkin's Lymphoma	GDSC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.25
p.T2355I	SIDM01566	Hodgkin's Lymphoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.1389
p.S1070G	SIDM00961	Ewing's Sarcoma	GDSC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.0833
p.S1070G	ACH-000210	Bone Cancer	CCLE	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.0833
p.S1070G	CADO-ES1	bone	COSMIC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.0833
p.T4003A	SIDM00499	Prostate Carcinoma	GDSC	PSTPRTT	DEG_SCF_FBW7_1	4011:4017	Mutation rewiring degron network	0.1111
p.T4003A	ACH-000956	Prostate Cancer	CCLE	PSTPRTT	DEG_SCF_FBW7_1	4011:4017	Mutation rewiring degron network	0.1111
p.T4003A	22RV1	prostate	COSMIC	PSTPRTT	DEG_SCF_FBW7_1	4011:4017	Mutation rewiring degron network	0.1111
p.V1403D	SIDM00884	Breast Carcinoma	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.7785
p.V1403D	SIDM00884	Breast Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation altering degron motif	0.6674
p.V1403D	SIDM01180	Hepatocellular Carcinoma	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.7785
p.V1403D	SIDM01180	Hepatocellular Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation altering degron motif	0.6674
p.V1403D	SIDM01318	Hepatocellular Carcinoma	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.7785
p.V1403D	SIDM01318	Hepatocellular Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation altering degron motif	0.6674
p.V1403D	SIDM01624	Bladder Carcinoma	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.7785
p.V1403D	SIDM01624	Bladder Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation altering degron motif	0.6674
p.V1403D	SIDM01689	B-Lymphoblastic Leukemia	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.7785
p.V1403D	SIDM01689	B-Lymphoblastic Leukemia	GDSC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation altering degron motif	0.6674
p.V1403D	SIDM01598	Non-Small Cell Lung Carcinoma	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.7785
p.V1403D	SIDM01598	Non-Small Cell Lung Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation altering degron motif	0.6674
p.V1403D	SIDM01758	B-Cell Non-Hodgkin's Lymphoma	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.7785
p.V1403D	SIDM01758	B-Cell Non-Hodgkin's Lymphoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation altering degron motif	0.6674
p.V1403D	SIDM01677	Non-Small Cell Lung Carcinoma	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.7785
p.V1403D	SIDM01677	Non-Small Cell Lung Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation altering degron motif	0.6674
p.T1170M	SIDM00958	Chronic Myelogenous Leukemia	GDSC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation altering degron motif	0.7423
p.T1170M	SIDM00982	Glioblastoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation altering degron motif	0.7423
p.T1170M	SIDM00901	Endometrial Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation altering degron motif	0.7423
p.L1692S	SIDM00608	Plasma Cell Myeloma	GDSC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.7667
p.L1692S	ACH-000714	Myeloma	CCLE	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.7667
p.L1692S	KMS-11	haematopoietic and lymphoid tissue	COSMIC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.7667
p.T3191N	SIDM01119	Other Solid Cancers	GDSC	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.25
p.T3191N	SIDM01119	Other Solid Cancers	GDSC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.0556
p.T3191N	ACH-000775	Lung Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.25
p.T3191N	ACH-000775	Lung Cancer	CCLE	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.0556
p.T3191N	NCI-H727	lung	COSMIC	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.25
p.T3191N	NCI-H727	lung	COSMIC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.0556
p.S3192R	SIDM01119	Other Solid Cancers	GDSC	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.2778
p.S3192R	SIDM01119	Other Solid Cancers	GDSC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.0833
p.S3192R	ACH-000775	Lung Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.2778
p.S3192R	ACH-000775	Lung Cancer	CCLE	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.0833
p.S3192R	NCI-H727	lung	COSMIC	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.2778
p.S3192R	NCI-H727	lung	COSMIC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.0833
p.G3932E	SIDM00545	Melanoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932E	ACH-000987	Skin Cancer	CCLE	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.G3932E	Mewo	skin	COSMIC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.0833
p.T1855I	SIDM00253	Neuroblastoma	GDSC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855I	SIDM01179	Other Sarcomas	GDSC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855I	SIDM00756	Non-Small Cell Lung Carcinoma	GDSC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.T1855I	SIDM00736	Non-Cancerous	GDSC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation rewiring degron network	0.1389
p.V1715I	SIDM00186	Kidney Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.1944
p.V1715I	SIDM00445	Esophageal Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.1944
p.V1715I	SIDM00003	Melanoma	GDSC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.1944
p.V1715I	SIDM01651	Non-Cancerous	GDSC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.1944
p.V1715I	SIDM01135	Pancreatic Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.1944
p.V1715I	SIDM00727	Non-Small Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	1720:1724	Mutation rewiring degron network	0.1944
p.S2824T	SIDM00186	Kidney Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.1667
p.S2824T	SIDM01651	Non-Cancerous	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.1667
p.S2824T	ACH-002353	Non-Cancerous	CCLE	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.1667
p.T3934I	SIDM00845	Burkitt's Lymphoma	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.1389
p.T3934I	SIDM00493	Other Solid Cancers	GDSC	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.1389
p.E3278D	SIDM01116	Non-Small Cell Lung Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.0833
p.E3278D	ACH-000789	Lung Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.0833
p.E3278D	NCI-H810	lung	COSMIC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.0833
p.V3470L	SIDM01116	Non-Small Cell Lung Carcinoma	GDSC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.2778
p.V3470L	ACH-000789	Lung Cancer	CCLE	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.2778
p.V3470L	NCI-H810	lung	COSMIC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.2778
p.E3691K	SIDM00336	Melanoma	GDSC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.0833
p.E3691K	ACH-000881	Skin Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.0833
p.E3691K	MEL-JUSO	skin	COSMIC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.0833
p.P1631L	SIDM00967	Ovarian Carcinoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation rewiring degron network	0.1389
p.P1631L	SIDM00721	Small Cell Lung Carcinoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation rewiring degron network	0.1389
p.P935L	SIDM00454	Rhabdomyosarcoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0833
p.P935L	SIDM00454	Rhabdomyosarcoma	GDSC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.3056
p.P935L	SIDM00746	Non-Small Cell Lung Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0833
p.P935L	SIDM00746	Non-Small Cell Lung Carcinoma	GDSC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.3056
p.P935L	SIDM00928	Breast Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0833
p.P935L	SIDM00928	Breast Carcinoma	GDSC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.3056
p.P935L	SIDM00814	Other Solid Cancers	GDSC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0833
p.P935L	SIDM00814	Other Solid Cancers	GDSC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.3056
p.P935L	SIDM00943	Pancreatic Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0833
p.P935L	SIDM00943	Pancreatic Carcinoma	GDSC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.3056
p.P935L	SIDM00956	Esophageal Squamous Cell Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0833
p.P935L	SIDM00956	Esophageal Squamous Cell Carcinoma	GDSC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.3056
p.P935L	SIDM00808	Burkitt's Lymphoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0833
p.P935L	SIDM00808	Burkitt's Lymphoma	GDSC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.3056
p.P935L	SIDM01254	Burkitt's Lymphoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.0833
p.P935L	SIDM01254	Burkitt's Lymphoma	GDSC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.3056
p.A3475V	SIDM00113	Kidney Carcinoma	GDSC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.1389
p.A3475V	ACH-001208	Kidney Cancer	CCLE	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.1389
p.A3475V	TK10	kidney	COSMIC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.1389
p.S313N	SIDM00565	Oral Cavity Carcinoma	GDSC	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.25
p.S313N	ACH-001626	Head and Neck Cancer	CCLE	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.25
p.S313N	OSC-20	upper aerodigestive tract	COSMIC	VITST	DEG_SPOP_SBC_1	306:310	Mutation rewiring degron network	0.25
p.L374F	SIDM00678	Bladder Carcinoma	GDSC	VTTST	DEG_SPOP_SBC_1	365:369	Mutation rewiring degron network	0.1944
p.L374F	SIDM01397	Melanoma	GDSC	VTTST	DEG_SPOP_SBC_1	365:369	Mutation rewiring degron network	0.1944
p.S2071Y	SIDM00025	Head and Neck Carcinoma	GDSC	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation altering degron motif	0.712
p.S2071Y	ACH-002391	Head and Neck Cancer	CCLE	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation altering degron motif	0.712
p.S2071Y	UDSCC2	upper aerodigestive tract	COSMIC	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation altering degron motif	0.712
p.M1583R	SIDM01199	Hepatocellular Carcinoma	GDSC	LSTTPIDS	DEG_SCF_FBW7_1	1593:1600	Mutation rewiring degron network	0.0556
p.M1583R	SIDM01677	Non-Small Cell Lung Carcinoma	GDSC	LSTTPIDS	DEG_SCF_FBW7_1	1593:1600	Mutation rewiring degron network	0.0556
p.S1753R	SIDM01126	Small Cell Lung Carcinoma	GDSC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation rewiring degron network	0.25
p.S1753R	SIDM01126	Small Cell Lung Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.2778
p.S1753R	ACH-001599	Lung Cancer	CCLE	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation rewiring degron network	0.25
p.S1753R	ACH-001599	Lung Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.2778
p.S1753R	NCI-H64	lung	COSMIC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation rewiring degron network	0.25
p.S1753R	NCI-H64	lung	COSMIC	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.2778
p.T2702K	SIDM01126	Small Cell Lung Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2712:2719	Mutation rewiring degron network	0.0556
p.T2702K	SIDM01147	Gastric Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2712:2719	Mutation rewiring degron network	0.0556
p.T3453S	SIDM01126	Small Cell Lung Carcinoma	GDSC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation altering degron motif	0.6005
p.T3453S	SIDM01147	Gastric Carcinoma	GDSC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation altering degron motif	0.6005
p.T4143S	SIDM01126	Small Cell Lung Carcinoma	GDSC	PRTTT	DEG_SPOP_SBC_1	4130:4134	Mutation rewiring degron network	0.0833
p.T4143S	SIDM01147	Gastric Carcinoma	GDSC	PRTTT	DEG_SPOP_SBC_1	4130:4134	Mutation rewiring degron network	0.0833
p.E4050A	SIDM01069	Non-Small Cell Lung Carcinoma	GDSC	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation altering degron motif	0.7701
p.E4050A	ACH-000667	Lung Cancer	CCLE	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation altering degron motif	0.7701
p.E4050A	HCC-44	lung	COSMIC	PVTPSSE	DEG_SCF_FBW7_2	4044:4050	Mutation altering degron motif	0.7701
p.P620T	SIDM00120	Prostate Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	607:611	Mutation rewiring degron network	0.0833
p.P620T	ACH-000979	Prostate Cancer	CCLE	ASSSS	DEG_SPOP_SBC_1	607:611	Mutation rewiring degron network	0.0833
p.P620T	DU-145	prostate	COSMIC	ASSSS	DEG_SPOP_SBC_1	607:611	Mutation rewiring degron network	0.0833
p.P1485T	SIDM00120	Prostate Carcinoma	GDSC	AVSSS	DEG_SPOP_SBC_1	1491:1495	Mutation rewiring degron network	0.1667
p.P1485T	ACH-000979	Prostate Cancer	CCLE	AVSSS	DEG_SPOP_SBC_1	1491:1495	Mutation rewiring degron network	0.1667
p.P1485T	DU-145	prostate	COSMIC	AVSSS	DEG_SPOP_SBC_1	1491:1495	Mutation rewiring degron network	0.1667
p.V3312G	SIDM00120	Prostate Carcinoma	GDSC	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.2222
p.V3312G	SIDM00120	Prostate Carcinoma	GDSC	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation rewiring degron network	0.2778
p.V3312G	ACH-000979	Prostate Cancer	CCLE	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.2222
p.V3312G	ACH-000979	Prostate Cancer	CCLE	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation rewiring degron network	0.2778
p.V3312G	DU-145	prostate	COSMIC	LSTTPADT	DEG_SCF_FBW7_1	3301:3308	Mutation rewiring degron network	0.2222
p.V3312G	DU-145	prostate	COSMIC	ADTST	DEG_SPOP_SBC_1	3306:3310	Mutation rewiring degron network	0.2778
p.A1786G	SIDM00496	Thyroid Gland Carcinoma	GDSC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.0556
p.A1786G	SIDM01005	Acute Myeloid Leukemia	GDSC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.0556
p.A1786G	SIDM00002	Neuroblastoma	GDSC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.0556
p.A1786G	SIDM00530	Esophageal Carcinoma	GDSC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.0556
p.A1786G	SIDM00585	Hepatocellular Carcinoma	GDSC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.0556
p.A1786G	SIDM00587	Biliary Tract Carcinoma	GDSC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.0556
p.A1786G	SIDM01024	Esophageal Squamous Cell Carcinoma	GDSC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.0556
p.A1786G	SIDM00324	Neuroblastoma	GDSC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.0556
p.A1786G	SIDM00326	Esophageal Squamous Cell Carcinoma	GDSC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.0556
p.A1786G	SIDM01660	Kidney Carcinoma	GDSC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.0556
p.A1786G	TE-8	oesophagus	COSMIC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.0556
p.A1786G	HuH-7	liver	COSMIC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.0556
p.A1786G	HuCCT1	biliary tract	COSMIC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.0556
p.A1786G	KASUMI-1	haematopoietic and lymphoid tissue	COSMIC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.0556
p.A1786G	KYSE-70	oesophagus	COSMIC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.0556
p.A1786G	NBsusSR	autonomic ganglia	COSMIC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.0556
p.A1786G	KYAE-1	oesophagus	COSMIC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.0556
p.A1786G	HTC-C3	thyroid	COSMIC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.0556
p.A1786G	TGW	autonomic ganglia	COSMIC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.0556
p.S3728F	SIDM01175	Other Sarcomas	GDSC	PVTTS	DEG_SPOP_SBC_1	3724:3728	Mutation altering degron motif	0.7982
p.S3728F	ACH-002309	Sarcoma	CCLE	PVTTS	DEG_SPOP_SBC_1	3724:3728	Mutation altering degron motif	0.7982
p.S3728F	SW684	soft tissue	COSMIC	PVTTS	DEG_SPOP_SBC_1	3724:3728	Mutation altering degron motif	0.7982
p.H3143Y	SIDM00216	Colorectal Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.2222
p.H3143Y	SNU-175	large intestine	COSMIC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.2222
p.L2358I	SIDM00594	Acute Myeloid Leukemia	GDSC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation altering degron motif	0.6063
p.L2358I	SIDM00263	Ewing's Sarcoma	GDSC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation altering degron motif	0.6063
p.L2358I	SIDM01780	B-Cell Non-Hodgkin's Lymphoma	GDSC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation altering degron motif	0.6063
p.P2050H	SIDM00291	Melanoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation altering degron motif	0.7694
p.P2050H	ACH-002040	Skin Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation altering degron motif	0.7694
p.P2050H	HMV-II	skin	COSMIC	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation altering degron motif	0.7694
p.P1544T	SIDM00656	Burkitt's Lymphoma	GDSC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.25
p.P1544T	SIDM00656	Burkitt's Lymphoma	GDSC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.3056
p.P1544T	ACH-000944	Lymphoma	CCLE	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.25
p.P1544T	ACH-000944	Lymphoma	CCLE	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.3056
p.P1544T	NAMALWA	haematopoietic and lymphoid tissue	COSMIC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.25
p.P1544T	NAMALWA	haematopoietic and lymphoid tissue	COSMIC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.3056
p.A194E	SIDM00506	Small Cell Lung Carcinoma	GDSC	MSTPLTT	DEG_SCF_FBW7_1	184:190	Mutation rewiring degron network	0.2222
p.A194E	SIDM00506	Small Cell Lung Carcinoma	GDSC	PLTTS	DEG_SPOP_SBC_1	187:191	Mutation rewiring degron network	0.25
p.A194E	SIDM00506	Small Cell Lung Carcinoma	GDSC	PESTT	DEG_SPOP_SBC_1	201:205	Mutation rewiring degron network	0.1389
p.A194E	COR-L88	lung	COSMIC	MSTPLTT	DEG_SCF_FBW7_1	184:190	Mutation rewiring degron network	0.2222
p.A194E	COR-L88	lung	COSMIC	PLTTS	DEG_SPOP_SBC_1	187:191	Mutation rewiring degron network	0.25
p.A194E	COR-L88	lung	COSMIC	PESTT	DEG_SPOP_SBC_1	201:205	Mutation rewiring degron network	0.1389
p.T3527I	SIDM00553	Acute Myeloid Leukemia	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation altering degron motif	0.7078
p.T3527I	SIDM00553	Acute Myeloid Leukemia	GDSC	PVSTT	DEG_SPOP_SBC_1	3523:3527	Mutation altering degron motif	0.7078
p.T3527I	SIDM01653	Non-Cancerous	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation altering degron motif	0.7078
p.T3527I	SIDM01653	Non-Cancerous	GDSC	PVSTT	DEG_SPOP_SBC_1	3523:3527	Mutation altering degron motif	0.7078
p.T3527I	SIDM00207	Glioblastoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation altering degron motif	0.7078
p.T3527I	SIDM00207	Glioblastoma	GDSC	PVSTT	DEG_SPOP_SBC_1	3523:3527	Mutation altering degron motif	0.7078
p.T3527I	SIDM01511	Gastric Carcinoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation altering degron motif	0.7078
p.T3527I	SIDM01511	Gastric Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	3523:3527	Mutation altering degron motif	0.7078
p.G1088C	SIDM00087	Plasma Cell Myeloma	GDSC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.1944
p.G1088C	SIDM00694	Other Solid Cancers	GDSC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.1944
p.G1088C	SIDM00032	Bladder Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.1944
p.G1088C	SIDM01409	Bladder Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.1944
p.G1088C	SCaBER	urinary tract	COSMIC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.1944
p.G1088C	HUTU-80	small intestine	COSMIC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.1944
p.G1088C	201T	lung	COSMIC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.1944
p.G1088C	RPMI-8226	haematopoietic and lymphoid tissue	COSMIC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.1944
p.S1267R	SIDM00087	Plasma Cell Myeloma	GDSC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.0833
p.S1267R	SIDM00087	Plasma Cell Myeloma	GDSC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.2778
p.S1267R	SIDM00694	Other Solid Cancers	GDSC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.0833
p.S1267R	SIDM00694	Other Solid Cancers	GDSC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.2778
p.S1267R	SIDM01409	Bladder Carcinoma	GDSC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.0833
p.S1267R	SIDM01409	Bladder Carcinoma	GDSC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.2778
p.C1375Y	SIDM00087	Plasma Cell Myeloma	GDSC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.2222
p.C1375Y	SIDM00694	Other Solid Cancers	GDSC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.2222
p.C1375Y	SIDM01409	Bladder Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.2222
p.G1618D	SIDM00087	Plasma Cell Myeloma	GDSC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.2222
p.G1618D	SIDM00694	Other Solid Cancers	GDSC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.2222
p.G1618D	SIDM00032	Bladder Carcinoma	GDSC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.2222
p.G1618D	SIDM01409	Bladder Carcinoma	GDSC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation rewiring degron network	0.2222
p.R1922G	SIDM00919	Ovarian Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.0556
p.R1922G	ACH-000713	Ovarian Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.0556
p.R1922G	Caov-3	ovary	COSMIC	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.0556
p.T3055A	SIDM01638	Non-Cancerous	GDSC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation altering degron motif	0.7139
p.T3055A	SIDM00172	Head and Neck Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation altering degron motif	0.7139
p.T3055A	ACH-002212	Head and Neck Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation altering degron motif	0.7139
p.T3055A	ACH-002342	Non-Cancerous	CCLE	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation altering degron motif	0.7139
p.D950N	SIDM00477	Esophageal Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation altering degron motif	0.5821
p.D950N	SIDM00477	Esophageal Carcinoma	GDSC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation altering degron motif	0.5821
p.D950N	ACH-000383	Esophageal Cancer	CCLE	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation altering degron motif	0.5821
p.D950N	ACH-000383	Esophageal Cancer	CCLE	VDTST	DEG_SPOP_SBC_1	949:953	Mutation altering degron motif	0.5821
p.D950N	OE33	oesophagus	COSMIC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation altering degron motif	0.5821
p.D950N	OE33	oesophagus	COSMIC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation altering degron motif	0.5821
p.H3143Q	SIDM00555	Glioblastoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.2222
p.H3143Q	ACH-000631	Brain Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.2222
p.H3143Q	KS-1	central nervous system	COSMIC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.2222
p.T3801N	SIDM00555	Glioblastoma	GDSC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.2222
p.T3801N	SIDM00301	Pancreatic Carcinoma	GDSC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.2222
p.T3801N	ACH-000265	Pancreatic Cancer	CCLE	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.2222
p.T3801N	ACH-000631	Brain Cancer	CCLE	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.2222
p.G2048R	SIDM01071	Small Cell Lung Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.2778
p.S3457N	SIDM00654	Small Cell Lung Carcinoma	GDSC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.2222
p.S3457N	SIDM00654	Small Cell Lung Carcinoma	GDSC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.1389
p.S1077F	SIDM01259	B-Lymphoblastic Leukemia	GDSC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.2778
p.P1284H	SIDM01078	Small Cell Lung Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation altering degron motif	0.7694
p.P1284H	ACH-000790	Lung Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation altering degron motif	0.7694
p.P1284H	SHP-77	lung	COSMIC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation altering degron motif	0.7694
p.N2077S	SIDM01028	Esophageal Squamous Cell Carcinoma	GDSC	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation rewiring degron network	0.1667
p.N2077S	ACH-000809	Esophageal Cancer	CCLE	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation rewiring degron network	0.1667
p.N2077S	KYSE-410	oesophagus	COSMIC	LSTTPVDS	DEG_SCF_FBW7_1	2064:2071	Mutation rewiring degron network	0.1667
p.A1551T	SIDM00669	Pancreatic Carcinoma	GDSC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.0556
p.A1551T	SIDM00669	Pancreatic Carcinoma	GDSC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.1111
p.A1551T	HPAF-II	pancreas	COSMIC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.0556
p.A1551T	HPAF-II	pancreas	COSMIC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.1111
p.S1341N	SIDM00660	Colorectal Carcinoma	GDSC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.5958
p.S1341N	SIDM00808	Burkitt's Lymphoma	GDSC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.5958
p.S1694N	SIDM00660	Colorectal Carcinoma	GDSC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.5958
p.S1694N	SIDM00808	Burkitt's Lymphoma	GDSC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.5958
p.S1694N	SIDM01173	Rhabdomyosarcoma	GDSC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.5958
p.S1694N	SIDM01254	Burkitt's Lymphoma	GDSC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation altering degron motif	0.5958
p.P2880S	SIDM00660	Colorectal Carcinoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.6752
p.P2880S	ACH-000985	Colon/Colorectal Cancer	CCLE	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.6752
p.P2880S	LS-411N	large intestine	COSMIC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation altering degron motif	0.6752
p.S3203L	SIDM00746	Non-Small Cell Lung Carcinoma	GDSC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation altering degron motif	0.7667
p.S3203L	NCI-H1648	lung	COSMIC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation altering degron motif	0.7667
p.S1174N	SIDM00190	Melanoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.2222
p.S1174N	ACH-002097	Skin Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.2222
p.S1174N	CP66-MEL	skin	COSMIC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.2222
p.T3193I	SIDM00442	Thyroid Gland Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.3056
p.T3193I	SIDM00442	Thyroid Gland Carcinoma	GDSC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.1111
p.T3193I	ML-1	thyroid	COSMIC	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.3056
p.T3193I	ML-1	thyroid	COSMIC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.1111
p.S362C	SIDM00744	Non-Small Cell Lung Carcinoma	GDSC	VTTST	DEG_SPOP_SBC_1	365:369	Mutation rewiring degron network	0.25
p.S362C	ACH-000893	Lung Cancer	CCLE	VTTST	DEG_SPOP_SBC_1	365:369	Mutation rewiring degron network	0.25
p.S362C	NCI-H1651	lung	COSMIC	VTTST	DEG_SPOP_SBC_1	365:369	Mutation rewiring degron network	0.25
p.V2173L	SIDM00700	Non-Small Cell Lung Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.2778
p.V2173L	ACH-001363	Lung Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.2778
p.V2173L	NCI-H2135	lung	COSMIC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.2778
p.P2457Q	SIDM00690	Head and Neck Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1944
p.P2457Q	ACH-002251	Head and Neck Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1944
p.P2457Q	JHU-029	upper aerodigestive tract	COSMIC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.1944
p.T1678I	SIDM01047	Chronic Myelogenous Leukemia	GDSC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation rewiring degron network	0.0556
p.T1678I	ACH-000295	Leukemia	CCLE	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation rewiring degron network	0.0556
p.T1678I	EM-2	haematopoietic and lymphoid tissue	COSMIC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation rewiring degron network	0.0556
p.P2851S	SIDM00354	Squamous Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation rewiring degron network	0.1389
p.P2851S	SIDM00195	Ewing's Sarcoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation rewiring degron network	0.1389
p.P2851S	SIDM00237	Non-Small Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation rewiring degron network	0.1389
p.P2851S	SIDM00380	Acute Myeloid Leukemia	GDSC	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation rewiring degron network	0.1389
p.P2851S	SIDM00316	Glioblastoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation rewiring degron network	0.1389
p.P2851S	SIDM01321	Pancreatic Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation rewiring degron network	0.1389
p.V937I	SIDM01122	Non-Small Cell Lung Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.1389
p.V937I	SIDM01122	Non-Small Cell Lung Carcinoma	GDSC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.25
p.V937I	ACH-000853	Lung Cancer	CCLE	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.1389
p.V937I	ACH-000853	Lung Cancer	CCLE	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.25
p.V937I	NCI-H661	lung	COSMIC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.1389
p.V937I	NCI-H661	lung	COSMIC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.25
p.S156N	SIDM01099	Neuroblastoma	GDSC	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation rewiring degron network	0.3056
p.T1778N	SIDM01099	Neuroblastoma	GDSC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.2778
p.S1846I	SIDM01099	Neuroblastoma	GDSC	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation altering degron motif	0.7341
p.S1846I	ACH-000341	Neuroblastoma	CCLE	AVSSS	DEG_SPOP_SBC_1	1844:1848	Mutation altering degron motif	0.7341
p.S1905I	SIDM01099	Neuroblastoma	GDSC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.0833
p.S1905I	SK-N-FI	autonomic ganglia	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.0833
p.Q3553P	SIDM01099	Neuroblastoma	GDSC	VTSSS	DEG_SPOP_SBC_1	3548:3552	Mutation rewiring degron network	0.3056
p.T3206A	SIDM00529	Breast Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.1111
p.T3206A	SIDM00529	Breast Carcinoma	GDSC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.3056
p.T3206A	SIDM00203	Ewing's Sarcoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.1111
p.T3206A	SIDM00203	Ewing's Sarcoma	GDSC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.3056
p.T3206A	SIDM00879	Breast Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.1111
p.T3206A	SIDM00879	Breast Carcinoma	GDSC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.3056
p.T3206A	SIDM00052	Esophageal Squamous Cell Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.1111
p.T3206A	SIDM00052	Esophageal Squamous Cell Carcinoma	GDSC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.3056
p.T3206A	SIDM00032	Bladder Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.1111
p.T3206A	SIDM00032	Bladder Carcinoma	GDSC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.3056
p.T3206A	SIDM00068	Colorectal Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.1111
p.T3206A	SIDM00068	Colorectal Carcinoma	GDSC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.3056
p.T3206A	SIDM01710	Squamous Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3194:3198	Mutation rewiring degron network	0.1111
p.T3206A	SIDM01710	Squamous Cell Lung Carcinoma	GDSC	ATSST	DEG_SPOP_SBC_1	3201:3205	Mutation rewiring degron network	0.3056
p.P856A	SIDM00998	Glioblastoma	GDSC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.1389
p.P856A	ACH-000137	Brain Cancer	CCLE	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.1389
p.P856A	8-MG-BA	central nervous system	COSMIC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.1389
p.P2244L	SIDM00763	Non-Small Cell Lung Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation altering degron motif	0.7582
p.P2244L	ACH-000434	Lung Cancer	CCLE	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation altering degron motif	0.7582
p.P2244L	NCI-H1915	lung	COSMIC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation altering degron motif	0.7582
p.T1179I	SIDM00260	Gastric Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.0833
p.T1179I	SIDM00248	Gastric Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.0833
p.T1179I	ACH-000758	Gastric Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.0833
p.T1179I	ACH-002161	Gastric Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.0833
p.T1179I	MKN28	stomach	COSMIC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.0833
p.P375T	SIDM00364	B-Lymphoblastic Leukemia	GDSC	VTTST	DEG_SPOP_SBC_1	365:369	Mutation rewiring degron network	0.1667
p.P375T	ACH-002059	Leukemia	CCLE	VTTST	DEG_SPOP_SBC_1	365:369	Mutation rewiring degron network	0.1667
p.P375T	P30-OHK	haematopoietic and lymphoid tissue	COSMIC	VTTST	DEG_SPOP_SBC_1	365:369	Mutation rewiring degron network	0.1667
p.D832N	SIDM00995	Other Solid Cancers	GDSC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation altering degron motif	0.5821
p.D832N	ACH-001328	Skin Cancer	CCLE	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation altering degron motif	0.5821
p.D832N	A431	skin	COSMIC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation altering degron motif	0.5821
p.S1168R	SIDM00965	Small Cell Lung Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation altering degron motif	0.7427
p.S1168R	ACH-000800	Lung Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation altering degron motif	0.7427
p.S1168R	NCI-H446	lung	COSMIC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation altering degron motif	0.7427
p.P3410L	SIDM01113	Other Sarcomas	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation altering degron motif	0.7582
p.P3410L	SIDM00900	Non-Cancerous	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation altering degron motif	0.7582
p.P3410L	SIDM01608	Endometrial Carcinoma	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation altering degron motif	0.7582
p.P3410L	SIDM01316	Ewing's Sarcoma	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation altering degron motif	0.7582
p.S4121G	SIDM00094	Kidney Carcinoma	GDSC	PRTTT	DEG_SPOP_SBC_1	4130:4134	Mutation rewiring degron network	0.0833
p.S4121G	ACH-002199	Kidney Cancer	CCLE	PRTTT	DEG_SPOP_SBC_1	4130:4134	Mutation rewiring degron network	0.0833
p.S4121G	SN12C	kidney	COSMIC	PRTTT	DEG_SPOP_SBC_1	4130:4134	Mutation rewiring degron network	0.0833
p.T1297N	SIDM01110	Hepatocellular Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.0833
p.T1297N	ACH-000361	Liver Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.0833
p.T1297N	SK-HEP-1	liver	COSMIC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.0833
p.T868I	SIDM00391	Plasma Cell Myeloma	GDSC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation altering degron motif	0.5966
p.T868I	ACH-000363	Myeloma	CCLE	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation altering degron motif	0.5966
p.T868I	SK-MM-2	haematopoietic and lymphoid tissue	COSMIC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation altering degron motif	0.5966
p.M161V	SIDM00014	Colorectal Carcinoma	GDSC	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation rewiring degron network	0.1667
p.M161V	LIM1215	large intestine	COSMIC	PMSTPSEE	DEG_SCF_FBW7_2	148:155	Mutation rewiring degron network	0.1667
p.P3129T	SIDM00983	Bladder Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.1667
p.P3129T	647-V	urinary tract	COSMIC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.1667
p.S1767N	SIDM00963	Breast Carcinoma	GDSC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation rewiring degron network	0.2222
p.S1767N	SIDM00963	Breast Carcinoma	GDSC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.2778
p.S1767N	SIDM00963	Breast Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.1111
p.M678K	SIDM00841	Colorectal Carcinoma	GDSC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.1111
p.M678K	ACH-000651	Colon/Colorectal Cancer	CCLE	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.1111
p.M678K	ACH-000842	Colon/Colorectal Cancer	CCLE	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.1111
p.M678K	SW620	large intestine	COSMIC	ATSSS	DEG_SPOP_SBC_1	666:670	Mutation rewiring degron network	0.1111
p.I1401M	SIDM01180	Hepatocellular Carcinoma	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.2778
p.I1401M	SIDM01180	Hepatocellular Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.3056
p.I1401M	SIDM01598	Non-Small Cell Lung Carcinoma	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.2778
p.I1401M	SIDM01598	Non-Small Cell Lung Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.3056
p.I1401M	SNU-387	liver	COSMIC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation rewiring degron network	0.2778
p.I1401M	SNU-387	liver	COSMIC	PVSTT	DEG_SPOP_SBC_1	1402:1406	Mutation rewiring degron network	0.3056
p.T1884S	SIDM00532	Glioma	GDSC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1111
p.T1884S	ACH-001125	Brain Cancer	CCLE	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1111
p.T1884S	MOG-G-CCM	central nervous system	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1111
p.V1697A	SIDM01003	T-Lymphoblastic Leukemia	GDSC	VRTTPVAS	DEG_SCF_FBW7_1	1697:1704	Mutation altering degron motif	0.6936
p.V1697A	ACH-000101	Leukemia	CCLE	VRTTPVAS	DEG_SCF_FBW7_1	1697:1704	Mutation altering degron motif	0.6936
p.V1697A	KE-37	haematopoietic and lymphoid tissue	COSMIC	VRTTPVAS	DEG_SCF_FBW7_1	1697:1704	Mutation altering degron motif	0.6936
p.T3441A	SIDM00290	Gastric Carcinoma	GDSC	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.1389
p.T3441A	SIDM00290	Gastric Carcinoma	GDSC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.1111
p.T3441A	ACH-000847	Gastric Cancer	CCLE	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.1389
p.T3441A	ACH-000847	Gastric Cancer	CCLE	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.1111
p.T3441A	HGC-27	stomach	COSMIC	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.1389
p.T3441A	HGC-27	stomach	COSMIC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.1111
p.P3695L	SIDM00290	Gastric Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.1944
p.P3695L	SIDM00214	Colorectal Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.1944
p.P3695L	SIDM00494	Non-Small Cell Lung Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.1944
p.P3695L	SIDM01463	Endometrial Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.1944
p.P3695L	SNU-407	large intestine	COSMIC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.1944
p.P3370H	SIDM00939	Non-Small Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7694
p.P3370H	ACH-000826	Lung Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7694
p.P3370H	CAL-12T	lung	COSMIC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.7694
p.S964Y	SIDM00505	Pancreatic Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.1667
p.S964Y	ACH-000601	Pancreatic Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.1667
p.S964Y	MIA-PaCa-2	pancreas	COSMIC	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.1667
p.T3284I	SIDM00221	Melanoma	GDSC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.25
p.S1282C	SIDM00653	Small Cell Lung Carcinoma	GDSC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.0833
p.S1282C	SIDM00653	Small Cell Lung Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.2778
p.S1282C	NCI-H1092	lung	COSMIC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.0833
p.S1282C	NCI-H1092	lung	COSMIC	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.2778
p.L2703V	SIDM01124	Non-Small Cell Lung Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2712:2719	Mutation rewiring degron network	0.0833
p.L2703V	ACH-000945	Lung Cancer	CCLE	LSTTPVDT	DEG_SCF_FBW7_1	2712:2719	Mutation rewiring degron network	0.0833
p.L2703V	NCI-H650	lung	COSMIC	LSTTPVDT	DEG_SCF_FBW7_1	2712:2719	Mutation rewiring degron network	0.0833
p.A941D	SIDM00148	Breast Carcinoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.25
p.A941D	SIDM00148	Breast Carcinoma	GDSC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1389
p.A941D	SIDM00148	Breast Carcinoma	GDSC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1111
p.A941D	MCF7	breast	COSMIC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation rewiring degron network	0.25
p.A941D	MCF7	breast	COSMIC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1389
p.A941D	MCF7	breast	COSMIC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation rewiring degron network	0.1111
p.S1639N	SIDM00237	Non-Small Cell Lung Carcinoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation altering degron motif	0.5958
p.S1639N	ACH-000030	Lung Cancer	CCLE	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation altering degron motif	0.5958
p.S1639N	ACH-000779	Lung Cancer	CCLE	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation altering degron motif	0.5958
p.S1639N	PC-14	lung	COSMIC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation altering degron motif	0.5958
p.T4027A	SIDM00498	Colorectal Carcinoma	GDSC	PSTPRTT	DEG_SCF_FBW7_1	4011:4017	Mutation rewiring degron network	0.0556
p.T4027A	SIDM00498	Colorectal Carcinoma	GDSC	PRTTS	DEG_SPOP_SBC_1	4014:4018	Mutation rewiring degron network	0.0833
p.T4027A	SIDM00498	Colorectal Carcinoma	GDSC	PHTST	DEG_SPOP_SBC_1	4034:4038	Mutation rewiring degron network	0.1389
p.T4027A	ACH-000970	Colon/Colorectal Cancer	CCLE	PSTPRTT	DEG_SCF_FBW7_1	4011:4017	Mutation rewiring degron network	0.0556
p.T4027A	ACH-000970	Colon/Colorectal Cancer	CCLE	PRTTS	DEG_SPOP_SBC_1	4014:4018	Mutation rewiring degron network	0.0833
p.T4027A	ACH-000970	Colon/Colorectal Cancer	CCLE	PHTST	DEG_SPOP_SBC_1	4034:4038	Mutation rewiring degron network	0.1389
p.T4027A	SNU-C5	large intestine	COSMIC	PSTPRTT	DEG_SCF_FBW7_1	4011:4017	Mutation rewiring degron network	0.0556
p.T4027A	SNU-C5	large intestine	COSMIC	PRTTS	DEG_SPOP_SBC_1	4014:4018	Mutation rewiring degron network	0.0833
p.T4027A	SNU-C5	large intestine	COSMIC	PHTST	DEG_SPOP_SBC_1	4034:4038	Mutation rewiring degron network	0.1389
p.S2824R	SIDM00410	Other Blood Cancers	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.1667
p.S2824R	ACH-002317	Leukemia	CCLE	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.1667
p.S2824R	YT	haematopoietic and lymphoid tissue	COSMIC	LSTTPVDT	DEG_SCF_FBW7_1	2830:2837	Mutation rewiring degron network	0.1667
p.M521I	SIDM00670	Pancreatic Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation rewiring degron network	0.0556
p.M521I	SIDM00749	Non-Small Cell Lung Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation rewiring degron network	0.0556
p.M521I	ACH-000916	Lung Cancer	CCLE	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation rewiring degron network	0.0556
p.M521I	HPAC	pancreas	COSMIC	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation rewiring degron network	0.0556
p.M521I	NCI-H1573	lung	COSMIC	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation rewiring degron network	0.0556
p.S3473C	SIDM00892	Breast Carcinoma	GDSC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.1944
p.S3473C	ACH-000818	Breast Cancer	CCLE	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.1944
p.S3473C	BT-483	breast	COSMIC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.1944
p.P925R	SIDM00032	Bladder Carcinoma	GDSC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.1944
p.L926F	SIDM00032	Bladder Carcinoma	GDSC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation rewiring degron network	0.2222
p.S1333T	SIDM00032	Bladder Carcinoma	GDSC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.2778
p.M3286V	SIDM01182	Bladder Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.3056
p.M3286V	ACH-000522	Bladder Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.3056
p.M3286V	UM-UC-3	urinary tract	COSMIC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.3056
p.S2529I	SIDM01190	Bladder Carcinoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation altering degron motif	0.7341
p.S2529I	ACH-000720	Bladder Cancer	CCLE	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation altering degron motif	0.7341
p.S2529I	TCCSUP	urinary tract	COSMIC	VSTTPVAS	DEG_SCF_FBW7_1	2522:2529	Mutation altering degron motif	0.7341
p.E556A	SIDM00126	Melanoma	GDSC	ASSSS	DEG_SPOP_SBC_1	548:552	Mutation rewiring degron network	0.2222
p.E556A	ACH-002147	Skin Cancer	CCLE	ASSSS	DEG_SPOP_SBC_1	548:552	Mutation rewiring degron network	0.2222
p.E556A	K2	skin	COSMIC	ASSSS	DEG_SPOP_SBC_1	548:552	Mutation rewiring degron network	0.2222
p.P3459A	SIDM00325	Esophageal Squamous Cell Carcinoma	GDSC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.1667
p.P3459A	SIDM00325	Esophageal Squamous Cell Carcinoma	GDSC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.1944
p.P3459A	ACH-000694	Esophageal Cancer	CCLE	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.1667
p.P3459A	ACH-000694	Esophageal Cancer	CCLE	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.1944
p.P3459A	TE-9	oesophagus	COSMIC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.1667
p.P3459A	TE-9	oesophagus	COSMIC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.1944
p.S3461L	SIDM00325	Esophageal Squamous Cell Carcinoma	GDSC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.1111
p.S3461L	SIDM00325	Esophageal Squamous Cell Carcinoma	GDSC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.25
p.S3461L	ACH-000694	Esophageal Cancer	CCLE	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.1111
p.S3461L	ACH-000694	Esophageal Cancer	CCLE	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.25
p.S3461L	TE-9	oesophagus	COSMIC	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.1111
p.S3461L	TE-9	oesophagus	COSMIC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.25
p.L3798V	SIDM00325	Esophageal Squamous Cell Carcinoma	GDSC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.1389
p.L3798V	ACH-000694	Esophageal Cancer	CCLE	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.1389
p.L3798V	TE-9	oesophagus	COSMIC	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation rewiring degron network	0.1389
p.P1125A	SIDM00070	B-Cell Non-Hodgkin's Lymphoma	GDSC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.1667
p.P1125A	CRO-AP3	NS	COSMIC	PVTTS	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.1667
p.V2771I	SIDM00400	B-Cell Non-Hodgkin's Lymphoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation rewiring degron network	0.0556
p.V2771I	ACH-002392	Lymphoma	CCLE	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation rewiring degron network	0.0556
p.V2771I	SC-1	haematopoietic and lymphoid tissue	COSMIC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation rewiring degron network	0.0556
p.T1379A	SIDM00574	Glioblastoma	GDSC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.1111
p.T1379A	ACH-001605	Brain Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.1111
p.T1379A	no-10	central nervous system	COSMIC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.1111
p.A2736V	SIDM00373	Endometrial Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2722:2726	Mutation rewiring degron network	0.0556
p.A2736V	ACH-000974	Endometrial/Uterine Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	2722:2726	Mutation rewiring degron network	0.0556
p.A2736V	SNG-M	endometrium	COSMIC	PVTTS	DEG_SPOP_SBC_1	2722:2726	Mutation rewiring degron network	0.0556
p.S1783Y	SIDM00344	Non-Small Cell Lung Carcinoma	GDSC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.1389
p.S1783Y	ACH-000596	Lung Cancer	CCLE	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.1389
p.S1783Y	LCLC-97TM1	lung	COSMIC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.1389
p.L1268F	SIDM00665	Gastric Carcinoma	GDSC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.0556
p.L1268F	SIDM00665	Gastric Carcinoma	GDSC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.3056
p.L1268F	ACH-000616	Gastric Cancer	CCLE	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.0556
p.L1268F	ACH-000616	Gastric Cancer	CCLE	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.3056
p.L1268F	Hs746T	stomach	COSMIC	AETSS	DEG_SPOP_SBC_1	1254:1258	Mutation rewiring degron network	0.0556
p.L1268F	Hs746T	stomach	COSMIC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.3056
p.P1361L	SIDM00918	Ovarian Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.1667
p.P1361L	ACH-000103	Ovarian Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.1667
p.P1361L	Caov-4	ovary	COSMIC	PVTTS	DEG_SPOP_SBC_1	1367:1371	Mutation rewiring degron network	0.1667
p.P2716S	SIDM00920	Breast Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	2712:2719	Mutation altering degron motif	0.6752
p.S3277I	SIDM00097	Breast Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.0556
p.S3277I	ACH-000147	Breast Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.0556
p.S3277I	T47D	breast	COSMIC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation rewiring degron network	0.0556
p.S3693I	SIDM00368	Small Cell Lung Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.1389
p.S3693I	ACH-000670	Lung Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.1389
p.V3529E	SIDM00749	Non-Small Cell Lung Carcinoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation altering degron motif	0.6582
p.V3529E	ACH-000916	Lung Cancer	CCLE	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation altering degron motif	0.6582
p.V3529E	NCI-H1573	lung	COSMIC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation altering degron motif	0.6582
p.P1269A	SIDM00217	Colorectal Carcinoma	GDSC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation altering degron motif	0.6392
p.P1269A	ACH-000999	Colon/Colorectal Cancer	CCLE	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation altering degron motif	0.6392
p.P1269A	SNU-1040	large intestine	COSMIC	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation altering degron motif	0.6392
p.P2893H	SIDM00217	Colorectal Carcinoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.0556
p.P2893H	ACH-000999	Colon/Colorectal Cancer	CCLE	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.0556
p.P2893H	SNU-1040	large intestine	COSMIC	VSTTPVAS	DEG_SCF_FBW7_1	2876:2883	Mutation rewiring degron network	0.0556
p.V3288A	SIDM00217	Colorectal Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation altering degron motif	0.5825
p.V3288A	SNU-1040	large intestine	COSMIC	PVSTT	DEG_SPOP_SBC_1	3287:3291	Mutation altering degron motif	0.5825
p.A1610D	SIDM00726	Non-Small Cell Lung Carcinoma	GDSC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation altering degron motif	0.7793
p.A1610D	NCI-H2347	lung	COSMIC	ASSST	DEG_SPOP_SBC_1	1610:1614	Mutation altering degron motif	0.7793
p.S1767I	SIDM00306	Non-Small Cell Lung Carcinoma	GDSC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation rewiring degron network	0.2222
p.S1767I	SIDM00306	Non-Small Cell Lung Carcinoma	GDSC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.2778
p.S1767I	SIDM00306	Non-Small Cell Lung Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.1111
p.S1767I	ACH-000672	Lung Cancer	CCLE	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation rewiring degron network	0.2222
p.S1767I	ACH-000672	Lung Cancer	CCLE	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.2778
p.S1767I	ACH-000672	Lung Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.1111
p.S1767I	IA-LM	lung	COSMIC	VSTTPVLS	DEG_SCF_FBW7_1	1756:1763	Mutation rewiring degron network	0.2222
p.S1767I	IA-LM	lung	COSMIC	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.2778
p.S1767I	IA-LM	lung	COSMIC	PVSTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.1111
p.T3973P	SIDM00721	Small Cell Lung Carcinoma	GDSC	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation altering degron motif	0.7031
p.T3973P	ACH-002171	Lung Cancer	CCLE	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation altering degron motif	0.7031
p.T3973P	NCI-H250	lung	COSMIC	LNTPSTS	DEG_SCF_FBW7_1	3971:3977	Mutation altering degron motif	0.7031
p.V3416D	SIDM00870	Breast Carcinoma	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.25
p.V3416D	ACH-000725	Breast Cancer	CCLE	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.25
p.V3416D	HCC202	breast	COSMIC	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.25
p.A194T	SIDM00118	Colorectal Carcinoma	GDSC	MSTPLTT	DEG_SCF_FBW7_1	184:190	Mutation rewiring degron network	0.2222
p.A194T	SIDM00118	Colorectal Carcinoma	GDSC	PLTTS	DEG_SPOP_SBC_1	187:191	Mutation rewiring degron network	0.25
p.A194T	SIDM00118	Colorectal Carcinoma	GDSC	PESTT	DEG_SPOP_SBC_1	201:205	Mutation rewiring degron network	0.1389
p.A194T	ACH-001081	Colon/Colorectal Cancer	CCLE	MSTPLTT	DEG_SCF_FBW7_1	184:190	Mutation rewiring degron network	0.2222
p.A194T	ACH-001081	Colon/Colorectal Cancer	CCLE	PLTTS	DEG_SPOP_SBC_1	187:191	Mutation rewiring degron network	0.25
p.A194T	ACH-001081	Colon/Colorectal Cancer	CCLE	PESTT	DEG_SPOP_SBC_1	201:205	Mutation rewiring degron network	0.1389
p.A194T	HCC2998	large intestine	COSMIC	MSTPLTT	DEG_SCF_FBW7_1	184:190	Mutation rewiring degron network	0.2222
p.A194T	HCC2998	large intestine	COSMIC	PLTTS	DEG_SPOP_SBC_1	187:191	Mutation rewiring degron network	0.25
p.A194T	HCC2998	large intestine	COSMIC	PESTT	DEG_SPOP_SBC_1	201:205	Mutation rewiring degron network	0.1389
p.P1544H	SIDM00274	Gastric Carcinoma	GDSC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.25
p.P1544H	SIDM00274	Gastric Carcinoma	GDSC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.3056
p.P1544H	ACH-000047	Gastric Cancer	CCLE	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.25
p.P1544H	ACH-000047	Gastric Cancer	CCLE	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.3056
p.P1544H	GCIY	stomach	COSMIC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.25
p.P1544H	GCIY	stomach	COSMIC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.3056
p.P821L	SIDM00150	Colorectal Carcinoma	GDSC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.1944
p.P821L	ACH-000969	Colon/Colorectal Cancer	CCLE	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.1944
p.P821L	KM12	large intestine	COSMIC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.1944
p.P3381H	SIDM00150	Colorectal Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation rewiring degron network	0.1389
p.P3381H	ACH-000969	Colon/Colorectal Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation rewiring degron network	0.1389
p.P3381H	KM12	large intestine	COSMIC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation rewiring degron network	0.1389
p.P3116Q	SIDM01131	Small Cell Lung Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	3111:3115	Mutation rewiring degron network	0.3056
p.P3116Q	ACH-000355	Lung Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	3111:3115	Mutation rewiring degron network	0.3056
p.P3116Q	NCI-H82	lung	COSMIC	PVSTT	DEG_SPOP_SBC_1	3111:3115	Mutation rewiring degron network	0.3056
p.S1529Y	SIDM00975	Melanoma	GDSC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.1944
p.S1529Y	SIDM00975	Melanoma	GDSC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.S1529Y	ACH-002206	Skin Cancer	CCLE	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.1944
p.S1529Y	ACH-002206	Skin Cancer	CCLE	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.S1529Y	WM278	skin	COSMIC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.1944
p.S1529Y	WM278	skin	COSMIC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.0556
p.T1329S	SIDM00808	Burkitt's Lymphoma	GDSC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.1667
p.T1329S	SIDM01254	Burkitt's Lymphoma	GDSC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.1667
p.T1329S	JiyoyeP-2003	haematopoietic and lymphoid tissue	COSMIC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation rewiring degron network	0.1667
p.T1682S	SIDM00808	Burkitt's Lymphoma	GDSC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation rewiring degron network	0.1667
p.T1682S	SIDM01254	Burkitt's Lymphoma	GDSC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation rewiring degron network	0.1667
p.T1682S	JiyoyeP-2003	haematopoietic and lymphoid tissue	COSMIC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation rewiring degron network	0.1667
p.T2843I	SIDM00755	Non-Small Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation altering degron motif	0.7078
p.T2843I	ACH-000888	Lung Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation altering degron motif	0.7078
p.T2843I	NCI-H1793	lung	COSMIC	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation altering degron motif	0.7078
p.T2164I	SIDM01372	Pancreatic Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.25
p.T2164I	ACH-000266	Pancreatic Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.25
p.T874N	SIDM01503	Small Cell Lung Carcinoma	GDSC	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.25
p.T874N	ACH-000844	Lung Cancer	CCLE	GRTPLTSMP	DEG_APCC_DBOX_1	863:871	Mutation rewiring degron network	0.25
p.P2344T	SIDM01318	Hepatocellular Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation altering degron motif	0.7031
p.P2344T	ACH-001318	Liver Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation altering degron motif	0.7031
p.A3655P	SIDM01551	Gastric Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	3641:3645	Mutation rewiring degron network	0.0556
p.A3655P	ACH-000485	Gastric Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	3641:3645	Mutation rewiring degron network	0.0556
p.P3469S	SIDM01608	Endometrial Carcinoma	GDSC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.3056
p.P3469S	ACH-000990	Endometrial/Uterine Cancer	CCLE	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.3056
p.P3469S	ACH-002287	Colon/Colorectal Cancer	CCLE	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.3056
p.P3469S	NCI-H630	large intestine	COSMIC	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.3056
p.G3959A	SIDM01449	Pancreatic Carcinoma	GDSC	VSTPVIT	DEG_SCF_FBW7_1	3961:3967	Mutation rewiring degron network	0.2778
p.G3959A	SIDM01449	Pancreatic Carcinoma	GDSC	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation rewiring degron network	0.0556
p.G3959A	SIDM01449	Pancreatic Carcinoma	GDSC	VITST	DEG_SPOP_SBC_1	3965:3969	Mutation rewiring degron network	0.1667
p.G3959A	ACH-000517	Pancreatic Cancer	CCLE	VSTPVIT	DEG_SCF_FBW7_1	3961:3967	Mutation rewiring degron network	0.2778
p.G3959A	ACH-000517	Pancreatic Cancer	CCLE	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation rewiring degron network	0.0556
p.G3959A	ACH-000517	Pancreatic Cancer	CCLE	VITST	DEG_SPOP_SBC_1	3965:3969	Mutation rewiring degron network	0.1667
p.T2180I	SIDM01613	Colorectal Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2167:2171	Mutation rewiring degron network	0.0833
p.T4490A	SIDM01617	Endometrial Carcinoma	GDSC	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation altering degron motif	0.7139
p.T4490A	ACH-000994	Endometrial/Uterine Cancer	CCLE	VMTTS	DEG_SPOP_SBC_1	4488:4492	Mutation altering degron motif	0.7139
p.T3127S	SIDM00017	Squamous Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.1111
p.T3127S	ACH-000912	Lung Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.1111
p.Q1903P	SIDM01511	Gastric Carcinoma	GDSC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	SIDM01776	Plasma Cell Myeloma	GDSC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	AM-38	central nervous system	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	GB-1	central nervous system	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	CML-T1	haematopoietic and lymphoid tissue	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	RERF-LC-Sq1	lung	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	GAK	skin	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	NMC-G1	central nervous system	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	RH-18	soft tissue	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	BFTC-909	kidney	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	TE-11	oesophagus	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	TMK-1	stomach	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	RCC-ER	kidney	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	YH-13	central nervous system	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	KMS-12-BM	haematopoietic and lymphoid tissue	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	SCaBER	urinary tract	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	LK-2	lung	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	201T	lung	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	NY	bone	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	JHH-6	liver	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	CAL-85-1	breast	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	KS-1	central nervous system	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	KYSE-140	oesophagus	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	HTC-C3	thyroid	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	KY821	haematopoietic and lymphoid tissue	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	IM-95	stomach	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	ECC10	stomach	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	SNU-61	large intestine	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	CCK-81	large intestine	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	OVISE	ovary	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903P	TE-12	oesophagus	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.T2842A	SIDM01739	Small Cell Lung Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	2840:2844	Mutation altering degron motif	0.7139
p.P1437T	SIDM00228	Thyroid Gland Carcinoma	GDSC	PGTTS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.1389
p.P1437T	ACH-000897	Thyroid Cancer	CCLE	PGTTS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.1389
p.V601E	SIDM01628	Non-Small Cell Lung Carcinoma	GDSC	VTTSS	DEG_SPOP_SBC_1	601:605	Mutation altering degron motif	0.7693
p.V601E	ACH-000851	Lung Cancer	CCLE	VTTSS	DEG_SPOP_SBC_1	601:605	Mutation altering degron motif	0.7693
p.E449K	SIDM01611	Endometrial Carcinoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation rewiring degron network	0.0556
p.E449K	SIDM01611	Endometrial Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	458:462	Mutation rewiring degron network	0.0833
p.E449K	ACH-000996	Endometrial/Uterine Cancer	CCLE	VSTTPVAS	DEG_SCF_FBW7_1	459:466	Mutation rewiring degron network	0.0556
p.E449K	ACH-000996	Endometrial/Uterine Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	458:462	Mutation rewiring degron network	0.0833
p.T3428N	SIDM01611	Endometrial Carcinoma	GDSC	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.2778
p.T3428N	ACH-000996	Endometrial/Uterine Cancer	CCLE	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.2778
p.S3728Y	SIDM01611	Endometrial Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3724:3728	Mutation altering degron motif	0.712
p.S3728Y	ACH-000996	Endometrial/Uterine Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	3724:3728	Mutation altering degron motif	0.712
p.T1682I	SIDM01776	Plasma Cell Myeloma	GDSC	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation rewiring degron network	0.1667
p.T1682I	ACH-001162	Myeloma	CCLE	GRTPLTSIT	DEG_APCC_DBOX_1	1688:1696	Mutation rewiring degron network	0.1667
p.S3104R	SIDM01776	Plasma Cell Myeloma	GDSC	PVSTT	DEG_SPOP_SBC_1	3111:3115	Mutation rewiring degron network	0.1389
p.S3113R	SIDM01776	Plasma Cell Myeloma	GDSC	PVSTT	DEG_SPOP_SBC_1	3111:3115	Mutation altering degron motif	0.7427
p.S2772A	SIDM00784	Glioma	GDSC	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation rewiring degron network	0.0833
p.S2772A	ACH-000126	Brain Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	2781:2785	Mutation rewiring degron network	0.0833
p.S1410N	SIDM00161	Biliary Tract Carcinoma	GDSC	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.7069
p.S1410N	ACH-000141	Gallbladder Cancer	CCLE	VSTTPVVS	DEG_SCF_FBW7_1	1403:1410	Mutation altering degron motif	0.7069
p.A3530V	SIDM01435	Hepatocellular Carcinoma	GDSC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation altering degron motif	0.5825
p.V2350G	SIDM00500	Colorectal Carcinoma	GDSC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.1111
p.V2350G	SIDM00500	Colorectal Carcinoma	GDSC	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.2778
p.V2350G	ACH-000959	Colon/Colorectal Cancer	CCLE	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation rewiring degron network	0.1111
p.V2350G	ACH-000959	Colon/Colorectal Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	2344:2348	Mutation rewiring degron network	0.2778
p.T723N	SIDM01520	Oral Cavity Carcinoma	GDSC	LSTTPVDT	DEG_SCF_FBW7_1	708:715	Mutation rewiring degron network	0.1111
p.T723N	SIDM01520	Oral Cavity Carcinoma	GDSC	VDTST	DEG_SPOP_SBC_1	713:717	Mutation rewiring degron network	0.1667
p.I1342V	SIDM01774	Pancreatic Carcinoma	GDSC	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.5965
p.I1342V	ACH-000205	Pancreatic Cancer	CCLE	GRTPLTSIP	DEG_APCC_DBOX_1	1335:1343	Mutation altering degron motif	0.5965
p.S3374Y	SIDM01588	Endometrial Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.712
p.S3374Y	ACH-000993	Endometrial/Uterine Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	3370:3374	Mutation altering degron motif	0.712
p.A2237V	SIDM01254	Burkitt's Lymphoma	GDSC	LSATPVDT	DEG_SCF_FBW7_1	2240:2247	Mutation rewiring degron network	0.25
p.T2365S	SIDM01215	Ovarian Carcinoma	GDSC	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation altering degron motif	0.6005
p.T2365S	ACH-000542	Ovarian Cancer	CCLE	LSTTPADT	DEG_SCF_FBW7_1	2358:2365	Mutation altering degron motif	0.6005
p.G2048D	ACH-000160	Rhabdoid	CCLE	PVSTT	DEG_SPOP_SBC_1	2050:2054	Mutation rewiring degron network	0.2778
p.S1077P	ACH-000430	Ovarian Cancer	CCLE	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.2778
p.S1077P	TYK-nu	ovary	COSMIC	ASSSS	DEG_SPOP_SBC_1	1079:1083	Mutation rewiring degron network	0.2778
p.T3526P	ACH-000679	Esophageal Cancer	CCLE	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation altering degron motif	0.5919
p.T3526P	ACH-000679	Esophageal Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	3523:3527	Mutation altering degron motif	0.7031
p.T3526P	OE19	oesophagus	COSMIC	VSTTPVAS	DEG_SCF_FBW7_1	3524:3531	Mutation altering degron motif	0.5919
p.T3526P	OE19	oesophagus	COSMIC	PVSTT	DEG_SPOP_SBC_1	3523:3527	Mutation altering degron motif	0.7031
p.V1697F	ACH-000791	Lung Cancer	CCLE	VRTTPVAS	DEG_SCF_FBW7_1	1697:1704	Mutation altering degron motif	0.7068
p.T1709I	ACH-000974	Endometrial/Uterine Cancer	CCLE	VRTTPVAS	DEG_SCF_FBW7_1	1697:1704	Mutation rewiring degron network	0.1944
p.T1709I	SNG-M	endometrium	COSMIC	VRTTPVAS	DEG_SCF_FBW7_1	1697:1704	Mutation rewiring degron network	0.1944
p.P3111S	ACH-000999	Colon/Colorectal Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	3111:3115	Mutation altering degron motif	0.6752
p.P3111S	SNU-1040	large intestine	COSMIC	PVSTT	DEG_SPOP_SBC_1	3111:3115	Mutation altering degron motif	0.6752
p.T943K	ACH-001321	Thyroid Cancer	CCLE	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation blocking phosphorylation signal	0.75
p.T943K	ACH-001321	Thyroid Cancer	CCLE	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation blocking phosphorylation signal	0.5278
p.T943K	ACH-001321	Thyroid Cancer	CCLE	VDTST	DEG_SPOP_SBC_1	949:953	Mutation blocking phosphorylation signal	0.6111
p.T943K	TT	thyroid	COSMIC	LSATPVDT	DEG_SCF_FBW7_1	944:951	Mutation blocking phosphorylation signal	0.75
p.T943K	TT	thyroid	COSMIC	PDSTT	DEG_SPOP_SBC_1	930:934	Mutation blocking phosphorylation signal	0.5278
p.T943K	TT	thyroid	COSMIC	VDTST	DEG_SPOP_SBC_1	949:953	Mutation blocking phosphorylation signal	0.6111
p.P954S	ACH-001380	Pancreatic Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	954:958	Mutation altering degron motif	0.6752
p.S1777G	ACH-001613	Leukemia	CCLE	LSATPIDT	DEG_SCF_FBW7_1	1769:1776	Mutation rewiring degron network	0.3056
p.P3052H	ACH-001623	Brain Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	3052:3056	Mutation altering degron motif	0.7694
p.T3132A	ACH-001664	Gastric Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	3135:3139	Mutation rewiring degron network	0.25
p.D3425G	ACH-001664	Gastric Cancer	CCLE	VTTST	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.1944
p.S3712I	ACH-001685	Lymphoma	CCLE	VTSTPVTT	DEG_SCF_FBW7_1	3720:3727	Mutation rewiring degron network	0.1111
p.S3712I	ACH-001685	Lymphoma	CCLE	PVSTT	DEG_SPOP_SBC_1	3700:3704	Mutation rewiring degron network	0.1111
p.T377I	ACH-001719	Ovarian Cancer	CCLE	VTTST	DEG_SPOP_SBC_1	365:369	Mutation rewiring degron network	0.1111
p.A3951V	ACH-001786	Colon/Colorectal Cancer	CCLE	IPSTPVTS	DEG_SCF_FBW7_1	3941:3948	Mutation rewiring degron network	0.25
p.A3951V	ACH-001786	Colon/Colorectal Cancer	CCLE	VSTPVIT	DEG_SCF_FBW7_1	3961:3967	Mutation rewiring degron network	0.0556
p.A3951V	ACH-001786	Colon/Colorectal Cancer	CCLE	PVTSS	DEG_SPOP_SBC_1	3945:3949	Mutation rewiring degron network	0.2778
p.S1930R	ACH-001796	Liposarcoma	CCLE	PVSTT	DEG_SPOP_SBC_1	1932:1936	Mutation rewiring degron network	0.2778
p.T369S	ACH-001853	Bile Duct Cancer	CCLE	VTTST	DEG_SPOP_SBC_1	365:369	Mutation altering degron motif	0.6005
p.P371A	ACH-001853	Bile Duct Cancer	CCLE	VTTST	DEG_SPOP_SBC_1	365:369	Mutation rewiring degron network	0.2778
p.T533I	ACH-001853	Bile Duct Cancer	CCLE	LSTTPVDT	DEG_SCF_FBW7_1	531:538	Mutation altering degron motif	0.5966
p.P541L	ACH-001853	Bile Duct Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	541:545	Mutation altering degron motif	0.7582
p.S709L	ACH-001973	Metastasis	CCLE	LSTTPVDT	DEG_SCF_FBW7_1	708:715	Mutation altering degron motif	0.6556
p.E3396K	ACH-001973	Metastasis	CCLE	VSTTPVVS	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.0556
p.G3456E	ACH-001982	Metastasis	CCLE	PTSTT	DEG_SPOP_SBC_1	3449:3453	Mutation rewiring degron network	0.25
p.G3456E	ACH-001982	Metastasis	CCLE	PLSTT	DEG_SPOP_SBC_1	3464:3468	Mutation rewiring degron network	0.1111
p.P3223L	ACH-002005	Skin Cancer	CCLE	MTPLTS	DEG_SCF_FBW7_1	3221:3226	Mutation altering degron motif	0.7582
p.G1276R	ACH-002061	Leukemia	CCLE	PTSTT	DEG_SPOP_SBC_1	1269:1273	Mutation rewiring degron network	0.25
p.G1276R	ACH-002061	Leukemia	CCLE	PVSTT	DEG_SPOP_SBC_1	1284:1288	Mutation rewiring degron network	0.1111
p.P817L	ACH-002256	Leukemia	CCLE	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.0833
p.P817L	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	LSTTPVDS	DEG_SCF_FBW7_1	826:833	Mutation rewiring degron network	0.0833
p.S3807L	ACH-002710	Sarcoma	CCLE	PMSTT	DEG_SPOP_SBC_1	3805:3809	Mutation altering degron motif	0.7667
p.D3072V	MKN7	stomach	COSMIC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation altering degron motif	0.6674
p.D3072V	KON	upper aerodigestive tract	COSMIC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation altering degron motif	0.6674
p.D3072V	HSC-3	upper aerodigestive tract	COSMIC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation altering degron motif	0.6674
p.D3072V	SNU-C5	large intestine	COSMIC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation altering degron motif	0.6674
p.D3072V	P31-FUJ	haematopoietic and lymphoid tissue	COSMIC	LSTTPVDS	DEG_SCF_FBW7_1	3066:3073	Mutation altering degron motif	0.6674
p.T2557I	Sarc9371	bone	COSMIC	VVTST	DEG_SPOP_SBC_1	2546:2550	Mutation rewiring degron network	0.1389
p.M2461I	MDA-MB-361	breast	COSMIC	PVSTT	DEG_SPOP_SBC_1	2462:2466	Mutation rewiring degron network	0.3056
p.Q1903E	BFTC-909	kidney	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903E	CAL-85-1	breast	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903E	YH-13	central nervous system	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903E	SNU-61	large intestine	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903E	KMS-12-BM	haematopoietic and lymphoid tissue	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903E	RH-18	soft tissue	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903E	RERF-LC-Sq1	lung	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903E	TMK-1	stomach	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903E	IM-95	stomach	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903E	LK-2	lung	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903E	RCC-ER	kidney	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903E	TE-11	oesophagus	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903E	GB-1	central nervous system	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903E	ECC10	stomach	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.Q1903E	JHH-6	liver	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1389
p.T1884I	SW982	soft tissue	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.1111
p.E1883D	Sarc9371	bone	COSMIC	AVTST	DEG_SPOP_SBC_1	1892:1896	Mutation rewiring degron network	0.0833
p.A1551V	SW982	soft tissue	COSMIC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.0556
p.A1551V	SW982	soft tissue	COSMIC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.1111
p.S1549A	SW982	soft tissue	COSMIC	LSTTPAVT	DEG_SCF_FBW7_1	1534:1541	Mutation rewiring degron network	0.1111
p.S1549A	SW982	soft tissue	COSMIC	AVTST	DEG_SPOP_SBC_1	1539:1543	Mutation rewiring degron network	0.1667
p.M1165V	AMO-1	haematopoietic and lymphoid tissue	COSMIC	PVSTT	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.3056
p.V1638L	AM-38	central nervous system	COSMIC	VSTTPVAS	DEG_SCF_FBW7_1	1638:1645	Mutation altering degron motif	0.5654

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MUC17

UniProt ID: Q685J3

Entrez ID: 140453

Protein name: Mucin-17 (MUC-17) (Small intestinal mucin-3) (MUC-3)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MUC17 in