KinaseMD: Kinase mutations and drug responses

Parent of:

Lmr, Abl, ALK, Axl, Src, Tec, PDGFR, Csk, DDR, EGFR, Eph, Fer, FGFR, VEGFR, InsR, Jak, Met, Musk, Trk, FAK, CCK4, Ret, Ror, Sev, Ryk, TK-Unique, Syk, Tie, Ack,

Description:

Tyrosine Kinase group. All active members phosphorylate tyrosine residues and are related by sequence similarity. Other dual specificity kinases (those which phosphorylate serine, threonine and tyrosine) are found scattered within other groups, but are not generally referred to as tyrosine kinases. This group is found in metazoans such as fly, worm and human, but not in single celled fungi.