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Dataset Description
  • Dataset Name: 15816859
  • Species: Human
  • Method: Microarray
  • No. of Genes: 103
  • Tissue: Prefrontal cortex and nucleus accumbens
  • Phenotype: Alcohol dependence (AD)/Alcohol abuse/Alcoholism
  • Publication: Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
  • Dataset Summary: Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test.

    Gene list of this dataset (103 genes)
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    7295TXNthioredoxin9q31AA150817 
    3551IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta8p11.2BQ014475 
    56287GKN1gastrokine 12p14AA099387 
    945CD33CD33 molecule19q13.3BI910568 
    8556CDC14ACDC14 cell division cycle 14 homolog A (S. cerevisiae)1p21AA002016 
    83667SESN2sestrin 21p35.3H51912 
    9252RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 514q31-q32.1AW968068 
    664BNIP3BCL2/adenovirus E1B 19kDa interacting protein 310q26.3BQ002402 
    7078TIMP3TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory)22q12.1-q13.2|22q12.3BQ044940 
    4192MDKmidkine (neurite growth-promoting factor 2)11p11.2W19684 
    273AMPHamphiphysin7p14-p13W01422 
    6383SDC2syndecan 28q22-q23BM971009 
    8936WASF1WAS protein family, member 16q21-q22N95702 
    4137MAPTmicrotubule-associated protein tau17q21.1BM725941 
    347APODapolipoprotein D3q26.2-qterAA131720 
    6696SPP1secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)4q21-q25R97904 
    5376PMP22peripheral myelin protein 2217p12-p11.2AA128253 
    10008KCNE3potassium voltage-gated channel, Isk-related family, member 311q13-q14AA127801 
    64924SLC30A5solute carrier family 30 (zinc transporter), member 55q12.1AA134752 
    1183CLCN4chloride channel 4Xp22.3AA071201 
    2550GABBR1gamma-aminobutyric acid (GABA) B receptor, 16p21.31W07715 
    6507SLC1A3solute carrier family 1 (glial high affinity glutamate transporter), member 35p13R59684 
        R85247 
    57326PBXIP1pre-B-cell leukemia homeobox interacting protein 11q21.3W07077 
    3706ITPKAinositol 1,4,5-trisphosphate 3-kinase A15q14-q21N48505 
    25939SAMHD1SAM domain and HD domain 120pter-q12BG536068 
        BM782955 
        BE874451 
        AV711588 
        BM794983 
        AV751900 
        BE873873 
        BM888296 
    26515FXC1fracture callus 1 homolog (rat)11p15.5-p15.3R92073 
    2108ETFAelectron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II)15q23-q25AA130253 
    4719NDUFS1NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)2q33-q34BM468661 
    729020hCG_2024410-10q24.33AL711113 
        N42285 
    134526ACOT12acyl-CoA thioesterase 125q14.1AA002136 
    48ACO1aconitase 1, soluble9p22-q32|9p21.1AA114871 
    51268PIPOXpipecolic acid oxidase17q11.2H66019 
        N78351 
    283209PGM2L1phosphoglucomutase 2-like 111q13.4N79332 
    13AADACarylacetamide deacetylase (esterase)3q21.3-q25.2N99791 
    130ADH6alcohol dehydrogenase 6 (class V)4q23W92014 
    7389URODuroporphyrinogen decarboxylase1p34BQ064110 
    7378UPP1uridine phosphorylase 17p12.3BQ017463 
    5690PSMB2proteasome (prosome, macropain) subunit, beta type, 21p34.2BQ050102 
    10772FUSIP1FUS interacting protein (serine/arginine-rich) 11p36.11BM014323 
    6235RPS29ribosomal protein S2914qBQ028504 
    56342PPANpeter pan homolog (Drosophila)19p13BQ051603 
    6146RPL22ribosomal protein L221p36.3-p36.2W15194 
    54925ZNF434zinc finger protein 43416p13.3H93281 
    1054CEBPGCCAAT/enhancer binding protein (C/EBP), gamma19q13.11AA055333 
    166793ZNF509zinc finger protein 5094p16.2N53915 
    7572ZNF24zinc finger protein 2418q12AA134770 
    7342UBP1upstream binding protein 1 (LBP-1a)3p22.3H63585 
    27107ZBTB11zinc finger and BTB domain containing 113q12.3N53706 
    5425POLD2polymerase (DNA directed), delta 2, regulatory subunit 50kDa7p13W01850 
    5371PMLpromyelocytic leukemia15q22W38850 
    10320IKZF1IKAROS family zinc finger 1 (Ikaros)7p13-p11.1W01226 
    80198MUS81MUS81 endonuclease homolog (S. cerevisiae)11q13N99229 
    29946SERTAD3SERTA domain containing 319q13.2N32669 
    6387CXCL12chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)10q11.1W02528 
    9404LPXNleupaxin11q12.1W00660 
    3123HLA-DRB1major histocompatibility complex, class II, DR beta 16p21.3H50622 
    10464PIBF1progesterone immunomodulatory binding factor 113q22.1AA099685 
        AA026536 
    5888RAD51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)15q15.1N72527 
    10745PHTF1putative homeodomain transcription factor 11p13N92222 
    55779WDR52WD repeat domain 523q13.2BM968725 
    9705ST18suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)8q11.23N47518 
    5694PSMB6proteasome (prosome, macropain) subunit, beta type, 617p13BQ052212 
    79048SECISBP2SECIS binding protein 29q22.2W58640 
    7336UBE2V2ubiquitin-conjugating enzyme E2 variant 28q11.21BI856490 
    51ACOX1acyl-Coenzyme A oxidase 1, palmitoyl17q24-q25|17q25.1H63016 
    5105PCK1phosphoenolpyruvate carboxykinase 1 (soluble)20q13.31R86197 
    23175LPIN1lipin 12p25.1N45520 
    54704PPM2Cprotein phosphatase 2C, magnesium-dependent, catalytic subunit8q22.1N47861 
    2181ACSL3acyl-CoA synthetase long-chain family member 32q34-q35N76698 
    4124MAN2A1mannosidase, alpha, class 2A, member 15q21-q22AA115560 
    2683B4GALT1UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 19p13W58426 
    760CA2carbonic anhydrase II8q22H23302 
        BE874451 
    22836RHOBTB3Rho-related BTB domain containing 35q15BM907252 
    2012EMP1epithelial membrane protein 112p12.3T75112 
    8573CASKcalcium/calmodulin-dependent serine protein kinase (MAGUK family)Xp11.4N92643 
    7533YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide22q12.3AA127798 
    65125WNK1WNK lysine deficient protein kinase 112p13.3H89618 
    1124CHN2chimerin (chimaerin) 27p15.3BG563170 
    6520SLC3A2solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 211q13BM771973 
    2907GRINAglutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)8q24.3R73412 
    26047CNTNAP2contactin associated protein-like 27q35-q36N53741 
    5376PMP22peripheral myelin protein 2217p12-p11.2AA128253 
    285958C7orf40chromosome 7 open reading frame 407p13N40823 
    4137MAPTmicrotubule-associated protein tau17q21.1BM725941 
    1282COL4A1collagen, type IV, alpha 113q34AA150402 
    3655ITGA6integrin, alpha 62q31.1H16046 
    26548ITGB1BP2integrin beta 1 binding protein (melusin) 2Xq12-q13.1AA134808 
    51148CERCAMcerebral endothelial cell adhesion molecule9q34.11AA137135 
    7077TIMP2TIMP metallopeptidase inhibitor 217q25BG542006 
    4815NINJ2ninjurin 212p13H91351 
    117178SSX2IPsynovial sarcoma, X breakpoint 2 interacting protein1p22.3H20898 
    7277TUBA4Atubulin, alpha 4a2q35W33064 
    6695SPOCK1sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 15q31AL566877 
    760CA2carbonic anhydrase II8q22H23302 
    9638FEZ1fasciculation and elongation protein zeta 1 (zygin I)11q24.2AA131602 
        BI916651 
    29970SCHIP1schwannomin interacting protein 13q25.33R35596 
    351APPamyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)21q21.2|21q21.3BM841483 
    9559VPS26Avacuolar protein sorting 26 homolog A (S. pombe)10q21.1T94596 
    3920LAMP2lysosomal-associated membrane protein 2Xq24R13247 
    6857SYT1synaptotagmin I12cen-q21N92197 
        N92095 
    5199CFPcomplement factor properdinXp11.3-p11.23H52352 
    10019SH2B3SH2B adaptor protein 312q24H77460 
    3554IL1R1interleukin 1 receptor, type I2q12W03241 
    7074TIAM1T-cell lymphoma invasion and metastasis 121q22.1|21q22.11AL533992 
    725C4BPBcomplement component 4 binding protein, beta1q32H78141